Show simple item record

dc.creatorAvramov Ivić, Milka
dc.creatorPetrović, Slobodan D.
dc.creatorMijin, Dušan
dc.creatorŽivković, Predrag M.
dc.creatorKosovic, IM
dc.creatorDrjevic, KM
dc.creatorJovanović, Mica B.
dc.date.accessioned2019-01-30T17:13:58Z
dc.date.available2019-01-30T17:13:58Z
dc.date.issued2006
dc.identifier.issn0013-4686
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/237
dc.description.abstractThe aim of the present study was to examine the oxidative properties and an assay of azithromycin and Hemomycin (R) at a gold electrode in neutral electrolyte using cyclic linear sweep voltammetry. The maximum value of the current of the oxidation peak of pure azithromycin and azithromycin from Hemomycin (R) at 0.6 V versus SCE in 0.05 M NaHCO3 and in a mixture methanol -0.05 M NaHCO3 (1:1) at a scan rate of 50 mV s(-1) is a linear function of the concentration in the range of 0.235-0.588 mg/cm(3). HPLC analysis of the bulk of electrolyte confirmed the data obtained by analysis of the values of the current peak concerning the concentration of antibiotic in the investigated concentration range. The role of methanol, when present, is discussed. In the case of azithromycin, the presence of methanol leads to higher current peak values. However, in the case of Hemonlycin (R), methanol should be avoided because of its inhibiting influence on the qualitative and quantitative determination of azithromycin and on the azithromycin/lactose, separation.en
dc.publisherOxford : Pergamon-Elsevier Science Ltd
dc.rightsrestrictedAccess
dc.sourceElectrochimica Acta
dc.subjectazithromycinen
dc.subjectHemomycin (R)en
dc.subjectcyclic voltammetryen
dc.subjectgold electrodeen
dc.subjectelectrochemical oxidationen
dc.titleStudies on electrochemical oxidation of azithromycin and Hemomycin (R) at gold electrode in neutral electrolyteen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКосовиц, ИМ; Дрјевиц, КМ; Петровић, Слободан Д.; Зивковиц, ПМ; Јовановиц, МБ; Мијин, ДЗ; Aврамов Ивић, Милка;
dc.citation.volume51
dc.citation.issue12
dc.citation.spage2407
dc.citation.epage2416
dc.citation.other51(12): 2407-2416
dc.citation.rankM21
dc.identifier.doi10.1016/j.electacta.2005.07.032
dc.identifier.scopus2-s2.0-32644452760
dc.identifier.wos000236019600003
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record