CER - Centralni Repozitorijum IHTM-a
Institut za hemiju, tehnologiju i metalurgiju
    • English
    • Српски
    • Српски (Serbia)
  • Srpski (latinica) 
    • Engleski
    • Srpski (ćirilica)
    • Srpski (latinica)
  • Prijava
Pregled zapisa 
  •   CER
  • IHTM
  • Radovi istraživača / Researchers' publications
  • Pregled zapisa
  •   CER
  • IHTM
  • Radovi istraživača / Researchers' publications
  • Pregled zapisa
JavaScript is disabled for your browser. Some features of this site may not work without it.

Advances in mathematical modelling of the hypothalamic-pituitary-adrenal (HPA) axis dynamics and the neuroendocrine response to stress

Samo za registrovane korisnike
2018
Autori
Stanojevic, Ana
Marković, Vladimir M.
Čupić, Željko
Kolar-Anić, Ljiljana
Vukojevic, Vladana
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentu
Apstrakt
Stress is a physiological reaction of an organism to a demand for change that is imposed by external factors or is coming from within by way of physiological strains or self-perceived mental and/or emotional threats (internal factors). It manifests itself through the sudden release of a flood of hormones, including corticosteroids, into the blood, which rouse the body for action. Normally, stress is beneficial, but when lasting or being very strong, it causes major damage to our mind and body. Despite intense research, we still do not understand fully how the stress response axis, whose main function is to respond to challenges while maintaining the normal physiological balance, loses under prolonged exposure to stressors its capacity to maintain homeostasis. Recent applications of mathematical modelling and dynamical systems theory have enabled us to emulate complex neurochemical transformations that underlie the stress response, and help us to acquire deeper understanding of this dyn...amical regulatory network.

Izvor:
Current Opinion in Chemical Engineering, 2018, 21, 84-95
Izdavač:
  • Elsevier Sci Ltd, Oxford
Finansiranje / projekti:
  • Swedish Research Council - VR 2016-01922
  • Rajko and Maj Dermanovic Fund
  • CMST COST Action Emergence and Evolution of Complex Chemical Systems - CM1304
  • Dinamika nelinearnih fizičkohemijskih i biohemijskih sistema sa modeliranjem i predviđanjem njihovih ponašanja pod neravnotežnim uslovima (RS-172015)
  • Nanostrukturni funkcionalni i kompozitni materijali u katalitičkim i sorpcionim procesima (RS-45001)

DOI: 10.1016/j.coche.2018.04.003

ISSN: 2211-3398

WoS: 000452899100012

Scopus: 2-s2.0-85046127842
[ Google Scholar ]
8
9
URI
https://cer.ihtm.bg.ac.rs/handle/123456789/2365
Kolekcije
  • Radovi istraživača / Researchers' publications
Institucija/grupa
IHTM
TY  - JOUR
AU  - Stanojevic, Ana
AU  - Marković, Vladimir M.
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
AU  - Vukojevic, Vladana
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2365
AB  - Stress is a physiological reaction of an organism to a demand for change that is imposed by external factors or is coming from within by way of physiological strains or self-perceived mental and/or emotional threats (internal factors). It manifests itself through the sudden release of a flood of hormones, including corticosteroids, into the blood, which rouse the body for action. Normally, stress is beneficial, but when lasting or being very strong, it causes major damage to our mind and body. Despite intense research, we still do not understand fully how the stress response axis, whose main function is to respond to challenges while maintaining the normal physiological balance, loses under prolonged exposure to stressors its capacity to maintain homeostasis. Recent applications of mathematical modelling and dynamical systems theory have enabled us to emulate complex neurochemical transformations that underlie the stress response, and help us to acquire deeper understanding of this dynamical regulatory network.
PB  - Elsevier Sci Ltd, Oxford
T2  - Current Opinion in Chemical Engineering
T1  - Advances in mathematical modelling of the hypothalamic-pituitary-adrenal (HPA) axis dynamics and the neuroendocrine response to stress
VL  - 21
SP  - 84
EP  - 95
DO  - 10.1016/j.coche.2018.04.003
ER  - 
@article{
author = "Stanojevic, Ana and Marković, Vladimir M. and Čupić, Željko and Kolar-Anić, Ljiljana and Vukojevic, Vladana",
year = "2018",
abstract = "Stress is a physiological reaction of an organism to a demand for change that is imposed by external factors or is coming from within by way of physiological strains or self-perceived mental and/or emotional threats (internal factors). It manifests itself through the sudden release of a flood of hormones, including corticosteroids, into the blood, which rouse the body for action. Normally, stress is beneficial, but when lasting or being very strong, it causes major damage to our mind and body. Despite intense research, we still do not understand fully how the stress response axis, whose main function is to respond to challenges while maintaining the normal physiological balance, loses under prolonged exposure to stressors its capacity to maintain homeostasis. Recent applications of mathematical modelling and dynamical systems theory have enabled us to emulate complex neurochemical transformations that underlie the stress response, and help us to acquire deeper understanding of this dynamical regulatory network.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Current Opinion in Chemical Engineering",
title = "Advances in mathematical modelling of the hypothalamic-pituitary-adrenal (HPA) axis dynamics and the neuroendocrine response to stress",
volume = "21",
pages = "84-95",
doi = "10.1016/j.coche.2018.04.003"
}
Stanojevic, A., Marković, V. M., Čupić, Ž., Kolar-Anić, L.,& Vukojevic, V.. (2018). Advances in mathematical modelling of the hypothalamic-pituitary-adrenal (HPA) axis dynamics and the neuroendocrine response to stress. in Current Opinion in Chemical Engineering
Elsevier Sci Ltd, Oxford., 21, 84-95.
https://doi.org/10.1016/j.coche.2018.04.003
Stanojevic A, Marković VM, Čupić Ž, Kolar-Anić L, Vukojevic V. Advances in mathematical modelling of the hypothalamic-pituitary-adrenal (HPA) axis dynamics and the neuroendocrine response to stress. in Current Opinion in Chemical Engineering. 2018;21:84-95.
doi:10.1016/j.coche.2018.04.003 .
Stanojevic, Ana, Marković, Vladimir M., Čupić, Željko, Kolar-Anić, Ljiljana, Vukojevic, Vladana, "Advances in mathematical modelling of the hypothalamic-pituitary-adrenal (HPA) axis dynamics and the neuroendocrine response to stress" in Current Opinion in Chemical Engineering, 21 (2018):84-95,
https://doi.org/10.1016/j.coche.2018.04.003 . .

DSpace software copyright © 2002-2015  DuraSpace
O Centralnom repozitorijumu (CeR) | Pošaljite zapažanja

re3dataOpenAIRERCUB
 

 

Kompletan repozitorijumInstitucije/grupeAutoriNasloviTemeOva institucijaAutoriNasloviTeme

Statistika

Pregled statistika

DSpace software copyright © 2002-2015  DuraSpace
O Centralnom repozitorijumu (CeR) | Pošaljite zapažanja

re3dataOpenAIRERCUB