Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.
TY - JOUR
AU - Lović, Jelena
AU - Trišović, Nemanja
AU - Antanasijevic, Jelena
AU - Avramov Ivić, Milka
PY - 2018
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/2313
AB - Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.
PB - International Association of Physical Chemists (IAPC)
T2 - Journal of Electrochemical Science and Engineering
T1 - Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution
VL - 8
IS - 2
SP - 163
EP - 170
DO - 10.5599/jese.481
ER -
@article{
author = "Lović, Jelena and Trišović, Nemanja and Antanasijevic, Jelena and Avramov Ivić, Milka",
year = "2018",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/2313",
abstract = "Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.",
publisher = "International Association of Physical Chemists (IAPC)",
journal = "Journal of Electrochemical Science and Engineering",
title = "Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution",
volume = "8",
number = "2",
pages = "163-170",
doi = "10.5599/jese.481"
}
Lović, J., Trišović, N., Antanasijevic, J.,& Avramov Ivić, M. (2018). Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution.
Journal of Electrochemical Science and Engineering
International Association of Physical Chemists (IAPC)., 8(2), 163-170.
https://doi.org/10.5599/jese.481
Lović J, Trišović N, Antanasijevic J, Avramov Ivić M. Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution. Journal of Electrochemical Science and Engineering. 2018;8(2):163-170
Lović Jelena, Trišović Nemanja, Antanasijevic Jelena, Avramov Ivić Milka, "Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution" Journal of Electrochemical Science and Engineering, 8, no. 2 (2018):163-170,
https://doi.org/10.5599/jese.481 .
