Zinc concentrations in human milk and infant serum during the first six months of lactation
Authorized Users Only
2017
Authors
Đurović, DijanaMilisavljevic, Branka
Mugosa, Boban
Lugonja, Nikoleta

Miletić, Srđan

Spasić, Snežana

Vrvić, Miroslav

Article (Published version)

Metadata
Show full item recordAbstract
Normal supply of zinc to the newborn via milk is essential for normal development. Using ICP-OES, we analyzed changes in the level of Zn in milk and infant serum in the neonatal period (Day 1 and Day 28 post partum) and at 6 months after delivery, in the cohort of 60 mothers and exclusively breastfed babies. Zn level in the serum showed increase (significant at 6 months) during this period (mg/mL): Day 1: 0.52 +/- 0.12; Day 28; 0.59 +/- 0.19; 6 months: 0.68 +/- 0.28. The concentration of Zn in the milk showed an opposite (decreasing) trend during the follow up: Day 1: 4.70 +/- 1.74 mg/L; Day 28: 2.65 +/- 1.06; 6 months: 0.46 +/- 0.36. A significant negative correlation was established between serum and milk [Zn] at day 28 (R = -0.338; p = 0.008), whereas a positive correlation was found at 6 months between these parameters (R = 0.306; p = 0.018). There was no significant correlation between [Zn] in the milk and serum and infants' body mass, mothers' age and mass at delivery. The level ...of Zn in the milk at 6 months of lactation is not sufficient to meet the recommended values. This implies that in Serbian population, Zn supplementation might be needed in the later phase of lactation.
Keywords:
Zinc / Human milk / Serum / Lactation / ICP-OES / NeonateSource:
Journal of Trace Elements in Medicine and Biology, 2017, 41, 75-78Publisher:
- Elsevier Gmbh, Urban & Fischer Verlag, Jena
Funding / projects:
DOI: 10.1016/j.jtemb.2017.02.012
ISSN: 0946-672X
PubMed: 28347466
WoS: 000399856500011
Scopus: 2-s2.0-85013765624
Collections
Institution/Community
IHTMTY - JOUR AU - Đurović, Dijana AU - Milisavljevic, Branka AU - Mugosa, Boban AU - Lugonja, Nikoleta AU - Miletić, Srđan AU - Spasić, Snežana AU - Vrvić, Miroslav PY - 2017 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2257 AB - Normal supply of zinc to the newborn via milk is essential for normal development. Using ICP-OES, we analyzed changes in the level of Zn in milk and infant serum in the neonatal period (Day 1 and Day 28 post partum) and at 6 months after delivery, in the cohort of 60 mothers and exclusively breastfed babies. Zn level in the serum showed increase (significant at 6 months) during this period (mg/mL): Day 1: 0.52 +/- 0.12; Day 28; 0.59 +/- 0.19; 6 months: 0.68 +/- 0.28. The concentration of Zn in the milk showed an opposite (decreasing) trend during the follow up: Day 1: 4.70 +/- 1.74 mg/L; Day 28: 2.65 +/- 1.06; 6 months: 0.46 +/- 0.36. A significant negative correlation was established between serum and milk [Zn] at day 28 (R = -0.338; p = 0.008), whereas a positive correlation was found at 6 months between these parameters (R = 0.306; p = 0.018). There was no significant correlation between [Zn] in the milk and serum and infants' body mass, mothers' age and mass at delivery. The level of Zn in the milk at 6 months of lactation is not sufficient to meet the recommended values. This implies that in Serbian population, Zn supplementation might be needed in the later phase of lactation. PB - Elsevier Gmbh, Urban & Fischer Verlag, Jena T2 - Journal of Trace Elements in Medicine and Biology T1 - Zinc concentrations in human milk and infant serum during the first six months of lactation VL - 41 SP - 75 EP - 78 DO - 10.1016/j.jtemb.2017.02.012 ER -
@article{ author = "Đurović, Dijana and Milisavljevic, Branka and Mugosa, Boban and Lugonja, Nikoleta and Miletić, Srđan and Spasić, Snežana and Vrvić, Miroslav", year = "2017", abstract = "Normal supply of zinc to the newborn via milk is essential for normal development. Using ICP-OES, we analyzed changes in the level of Zn in milk and infant serum in the neonatal period (Day 1 and Day 28 post partum) and at 6 months after delivery, in the cohort of 60 mothers and exclusively breastfed babies. Zn level in the serum showed increase (significant at 6 months) during this period (mg/mL): Day 1: 0.52 +/- 0.12; Day 28; 0.59 +/- 0.19; 6 months: 0.68 +/- 0.28. The concentration of Zn in the milk showed an opposite (decreasing) trend during the follow up: Day 1: 4.70 +/- 1.74 mg/L; Day 28: 2.65 +/- 1.06; 6 months: 0.46 +/- 0.36. A significant negative correlation was established between serum and milk [Zn] at day 28 (R = -0.338; p = 0.008), whereas a positive correlation was found at 6 months between these parameters (R = 0.306; p = 0.018). There was no significant correlation between [Zn] in the milk and serum and infants' body mass, mothers' age and mass at delivery. The level of Zn in the milk at 6 months of lactation is not sufficient to meet the recommended values. This implies that in Serbian population, Zn supplementation might be needed in the later phase of lactation.", publisher = "Elsevier Gmbh, Urban & Fischer Verlag, Jena", journal = "Journal of Trace Elements in Medicine and Biology", title = "Zinc concentrations in human milk and infant serum during the first six months of lactation", volume = "41", pages = "75-78", doi = "10.1016/j.jtemb.2017.02.012" }
Đurović, D., Milisavljevic, B., Mugosa, B., Lugonja, N., Miletić, S., Spasić, S.,& Vrvić, M.. (2017). Zinc concentrations in human milk and infant serum during the first six months of lactation. in Journal of Trace Elements in Medicine and Biology Elsevier Gmbh, Urban & Fischer Verlag, Jena., 41, 75-78. https://doi.org/10.1016/j.jtemb.2017.02.012
Đurović D, Milisavljevic B, Mugosa B, Lugonja N, Miletić S, Spasić S, Vrvić M. Zinc concentrations in human milk and infant serum during the first six months of lactation. in Journal of Trace Elements in Medicine and Biology. 2017;41:75-78. doi:10.1016/j.jtemb.2017.02.012 .
Đurović, Dijana, Milisavljevic, Branka, Mugosa, Boban, Lugonja, Nikoleta, Miletić, Srđan, Spasić, Snežana, Vrvić, Miroslav, "Zinc concentrations in human milk and infant serum during the first six months of lactation" in Journal of Trace Elements in Medicine and Biology, 41 (2017):75-78, https://doi.org/10.1016/j.jtemb.2017.02.012 . .