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dc.creatorKaraman, M.
dc.creatorJanjušević, L.
dc.creatorJakovljević, Dragica
dc.creatorŠibul, F.
dc.creatorPejin, Boris
dc.date.accessioned2019-01-30T17:55:47Z
dc.date.available2019-01-30T17:55:47Z
dc.date.issued2017
dc.identifier.issn1478-6419
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/2214
dc.description.abstractThis study outlines antioxidant and anti-AChE activities of the polysaccharide (PSH) extract from the mushroom species Amanita strobiliformis. Both the presence of α and ß glucans within the aforementioned extract was recorded. PSH extract displayed a profound scavenging activity of OH radicals (IC50 value, 11.86 ± 0.59 μg/mL) and high potential for reduction of Fe3+ ions (174.11 ± 8.70 mg eq. AA/g d.w.) being almost 48- and 5-fold more effective than mannitol and butylated hydroxytoluene used as a positive control, respectively. Compared with galanthamine (0.001 μg), the same extract exhibited a moderate anti-AChE activity (10 μg) in solid. Since purified PSH extract exhibited higher bioactivity (IC50 value 7.27 ± 0.31 μg/mL, 197.68 ± 9.47 mg eq. AA/g d.w. and 0.1 μg, respectively), it can be predominantly ascribed to the polysaccharide compounds. A. strobiliformis PSH extract may be considered as a promising resource of potent bioactive polysaccharides of natural origin successfully addressing both oxidative stress and lack of acetylcholine.en
dc.publisherTaylor and Francis Ltd.
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43002/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43004/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//
dc.rightsrestrictedAccess
dc.sourceNatural Product Research
dc.subjectAmanitaceaeen
dc.subjectbiological activityen
dc.subjectMushroomsen
dc.subjectpolar extracten
dc.titleAnti-hydroxyl radical activity, redox potential and anti-AChE activity of Amanita strobiliformis polysaccharide extracten
dc.typearticle
dc.rights.licenseARR
dcterms.abstractШибул, Ф.; Јаковљевић, Драгица; Караман, М.; Пејин, Б.; Јањушевић, Л.;
dc.citation.spage1
dc.citation.epage5
dc.citation.other: 1-5
dc.citation.rankM22
dc.identifier.doi10.1080/14786419.2017.1422183
dc.identifier.rcubConv_4438
dc.identifier.scopus2-s2.0-85039854192
dc.identifier.wos000469243700024
dc.type.versionpublishedVersion


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