Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
Keywords:
Angelica / Staphylococcus aureus / Escherichia coli / MIC / MBC
TY - JOUR
AU - Aćimović, Milica
AU - Pavlovic, Snezana D.
AU - Varga, Ana
AU - Filipović, Vladimir M.
AU - Cvetković, Mirjana
AU - Stanković, Jovana
AU - Čabarkapa, Ivana
PY - 2017
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/2192
AB - Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
PB - Natural Product Incorporation
T2 - Natural Product Communications
T1 - Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil
VL - 12
IS - 2
SP - 205
EP - 206
ER -
@article{
author = "Aćimović, Milica and Pavlovic, Snezana D. and Varga, Ana and Filipović, Vladimir M. and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2017",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/2192",
abstract = "Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil",
volume = "12",
number = "2",
pages = "205-206"
}
Aćimović, M., Pavlovic, S. D., Varga, A., Filipović, V. M., Cvetković, M., Stanković, J.,& Čabarkapa, I. (2017). Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil.
Natural Product Communications
Natural Product Incorporation., 12(2), 205-206.
Aćimović M, Pavlovic SD, Varga A, Filipović VM, Cvetković M, Stanković J, Čabarkapa I. Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. Natural Product Communications. 2017;12(2):205-206
Aćimović Milica, Pavlovic Snezana D., Varga Ana, Filipović Vladimir M., Cvetković Mirjana, Stanković Jovana, Čabarkapa Ivana, "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil" Natural Product Communications, 12, no. 2 (2017):205-206
