Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
Keywords:
Angelica / Staphylococcus aureus / Escherichia coli / MIC / MBC
TY - JOUR
AU - Aćimović, Milica
AU - Pavlovic, Snezana D.
AU - Varga, Ana O.
AU - Filipović, Vladimir M.
AU - Cvetković, Mirjana
AU - Stanković, Jovana
AU - Čabarkapa, Ivana
PY - 2017
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/2192
AB - Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.
PB - Natural Product Incorporation
T2 - Natural Product Communications
T1 - Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil
VL - 12
IS - 2
SP - 205
EP - 206
ER -
@article{
author = "Aćimović, Milica and Pavlovic, Snezana D. and Varga, Ana O. and Filipović, Vladimir M. and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2017",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/2192",
abstract = "Roots of wild growing Angelica archangelica L. from Mt. Ozren (Serbia) were subjected to hydrodistillation and GC-MS analysis. The roots contained 0.10% of essential oil with alpha-pinene (29.7%), delta-3-carene (14.2%), and a mixture of beta-phellandrene and limonene (13.2%) as main compounds. The modified resazurin microtiter-plate assay was used to evaluate the antibacterial activity of the essential oil against Staphylococcus aureus and Escherichia coli. The minimum inhibitory concentration (MIC) values were 14.2 mu L/mL for S. aureus and 28.4 mu L/mL for E. coli, while the minimum bactericidal concentrations (MBC) were 56.8 mu L/mL and 113.6 mu L/mL, respectively. According to the obtained results, the angelica root essential oil can be applied as a natural preservative in food and as a natural antibiotic for the treatment of several infectious diseases caused by these two bacteria.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil",
volume = "12",
number = "2",
pages = "205-206"
}
Aćimović M, Pavlovic SD, Varga AO, Filipović VM, Cvetković M, Stanković J, Čabarkapa I. Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil. Natural Product Communications. 2017;12(2):205-206
Aćimović, M., Pavlovic, S. D., Varga, A. O., Filipović, V. M., Cvetković, M., Stanković, J.,& Čabarkapa, I. (2017). Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil.
Natural Product CommunicationsNatural Product Incorporation., 12(2), 205-206.
Aćimović Milica, Pavlovic Snezana D., Varga Ana O., Filipović Vladimir M., Cvetković Mirjana, Stanković Jovana, Čabarkapa Ivana, "Chemical Composition and Antibacterial Activity of Angelica archangelica Root Essential Oil" 12, no. 2 (2017):205-206
