Antibacterial and antifungal properties of guanylhydrazones
2017
Autori
Ajdačić, VladimirLazić, Jelena
Mojicevic, Marija
Šegan, Sandra
Nikodinović-Runić, Jasmina
Opsenica, Igor
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
A series of novel guanylhydrazones were designed, synthesized and characterized. All the compounds were screened for their antibacterial and antifungal activity. Compounds 26 and 27 showed excellent antibacterial activities against Staphylococcus aureus ATCC 25923 and Micrococcus luteus ATCC 379 with minimal inhibitory concentrations of 4 ae g mL(-1), and good antifungal activity against Candida parapsilosis ATCC 22019. These results suggested that the selected guanylhydrazones could serve as promising leads for improved antimicrobial development.
Ključne reči:
guanylhydrazones / iminoguanidines / antibacterial activity / antifungal activity / Candida spp.Izvor:
Journal of the Serbian Chemical Society, 2017, 82, 6, 641-649Izdavač:
- Serbian Chemical Soc, Belgrade
Finansiranje / projekti:
- Sinteza aminohinolina i njihovih derivata kao antimalarika i inhibitora botulinum neurotoksina A (RS-MESTD-Basic Research (BR or ON)-172008)
- Izučavanje mikrobiološkog diverziteta i karakterizacija korisnih sredinskih mikroorganizama (RS-MESTD-Basic Research (BR or ON)-173048)
- Serbian Academy of Sciences and Arts
DOI: 10.2298/JSC170213033A
ISSN: 0352-5139
WoS: 000408085700003
Scopus: 2-s2.0-85026736401
Institucija/grupa
IHTMTY - JOUR AU - Ajdačić, Vladimir AU - Lazić, Jelena AU - Mojicevic, Marija AU - Šegan, Sandra AU - Nikodinović-Runić, Jasmina AU - Opsenica, Igor PY - 2017 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2138 AB - A series of novel guanylhydrazones were designed, synthesized and characterized. All the compounds were screened for their antibacterial and antifungal activity. Compounds 26 and 27 showed excellent antibacterial activities against Staphylococcus aureus ATCC 25923 and Micrococcus luteus ATCC 379 with minimal inhibitory concentrations of 4 ae g mL(-1), and good antifungal activity against Candida parapsilosis ATCC 22019. These results suggested that the selected guanylhydrazones could serve as promising leads for improved antimicrobial development. PB - Serbian Chemical Soc, Belgrade T2 - Journal of the Serbian Chemical Society T1 - Antibacterial and antifungal properties of guanylhydrazones VL - 82 IS - 6 SP - 641 EP - 649 DO - 10.2298/JSC170213033A ER -
@article{ author = "Ajdačić, Vladimir and Lazić, Jelena and Mojicevic, Marija and Šegan, Sandra and Nikodinović-Runić, Jasmina and Opsenica, Igor", year = "2017", abstract = "A series of novel guanylhydrazones were designed, synthesized and characterized. All the compounds were screened for their antibacterial and antifungal activity. Compounds 26 and 27 showed excellent antibacterial activities against Staphylococcus aureus ATCC 25923 and Micrococcus luteus ATCC 379 with minimal inhibitory concentrations of 4 ae g mL(-1), and good antifungal activity against Candida parapsilosis ATCC 22019. These results suggested that the selected guanylhydrazones could serve as promising leads for improved antimicrobial development.", publisher = "Serbian Chemical Soc, Belgrade", journal = "Journal of the Serbian Chemical Society", title = "Antibacterial and antifungal properties of guanylhydrazones", volume = "82", number = "6", pages = "641-649", doi = "10.2298/JSC170213033A" }
Ajdačić, V., Lazić, J., Mojicevic, M., Šegan, S., Nikodinović-Runić, J.,& Opsenica, I.. (2017). Antibacterial and antifungal properties of guanylhydrazones. in Journal of the Serbian Chemical Society Serbian Chemical Soc, Belgrade., 82(6), 641-649. https://doi.org/10.2298/JSC170213033A
Ajdačić V, Lazić J, Mojicevic M, Šegan S, Nikodinović-Runić J, Opsenica I. Antibacterial and antifungal properties of guanylhydrazones. in Journal of the Serbian Chemical Society. 2017;82(6):641-649. doi:10.2298/JSC170213033A .
Ajdačić, Vladimir, Lazić, Jelena, Mojicevic, Marija, Šegan, Sandra, Nikodinović-Runić, Jasmina, Opsenica, Igor, "Antibacterial and antifungal properties of guanylhydrazones" in Journal of the Serbian Chemical Society, 82, no. 6 (2017):641-649, https://doi.org/10.2298/JSC170213033A . .