Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.
TY - JOUR
AU - Božić, Aleksandra R.
AU - Filipovic, Nenad R.
AU - Novaković, Irena
AU - Bjelogrlić, Snežana K.
AU - Nikolić, Jasmina B.
AU - Drmanić, Saša Ž.
AU - Marinković, Aleksandar D.
PY - 2017
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2130
AB - Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.
PB - Serbian Chemical Society
T2 - Journal of the Serbian Chemical Society
T1 - Synthesis, antioxidant and antimicrobial activity of carbohydrazones
VL - 82
IS - 5
SP - 495
EP - 508
DO - 10.2298/JSC161220045B
ER -
@article{
author = "Božić, Aleksandra R. and Filipovic, Nenad R. and Novaković, Irena and Bjelogrlić, Snežana K. and Nikolić, Jasmina B. and Drmanić, Saša Ž. and Marinković, Aleksandar D.",
year = "2017",
abstract = "Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis, antioxidant and antimicrobial activity of carbohydrazones",
volume = "82",
number = "5",
pages = "495-508",
doi = "10.2298/JSC161220045B"
}
Božić, A. R., Filipovic, N. R., Novaković, I., Bjelogrlić, S. K., Nikolić, J. B., Drmanić, S. Ž.,& Marinković, A. D.. (2017). Synthesis, antioxidant and antimicrobial activity of carbohydrazones. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 82(5), 495-508.
https://doi.org/10.2298/JSC161220045B
Božić AR, Filipovic NR, Novaković I, Bjelogrlić SK, Nikolić JB, Drmanić SŽ, Marinković AD. Synthesis, antioxidant and antimicrobial activity of carbohydrazones. in Journal of the Serbian Chemical Society. 2017;82(5):495-508.
doi:10.2298/JSC161220045B .
Božić, Aleksandra R., Filipovic, Nenad R., Novaković, Irena, Bjelogrlić, Snežana K., Nikolić, Jasmina B., Drmanić, Saša Ž., Marinković, Aleksandar D., "Synthesis, antioxidant and antimicrobial activity of carbohydrazones" in Journal of the Serbian Chemical Society, 82, no. 5 (2017):495-508,
https://doi.org/10.2298/JSC161220045B . .
