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dc.creatorKonstantinović, Sandra S.
dc.creatorZlatkovic, Milica Z.
dc.creatorCiric, Jovan T.
dc.creatorIlić, Slavica B.
dc.creatorGojgić-Cvijović, Gordana
dc.creatorVeljković, Vlada B.
dc.date.accessioned2019-01-30T17:53:30Z
dc.date.available2019-01-30T17:53:30Z
dc.date.issued2017
dc.identifier.issn0367-598X
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/2102
dc.description.abstractIn the present work, four derivatives of salicylaldehyde (salicylaldehyde-hydrazone, phenylhydrazone, semicarbazone and thiosemicarbazone) were synthesized using both conventional (95% ethanol) and green (crude glycerol from biodiesel production) solvents. The obtained compounds were identified by elemental microanalysis, as well as FTIR, UV/Vis and H-1-NMR spectroscopic methods. Yields of 93-98% of the compounds in crude glycerol were achieved within 10-25 min. The derivatives of salicylaldehyde and crude glycerol were used as a nitrogen and carbon source, respectively, in the medium for antibiotic (hexaene H-85 and azalomycine B) production by Streptomyces hygroscopicus CH-7. The highest concentrations of hexaene H-85 and azalomycine B were achieved in the medium containing salicylaldehyde-thiosemicarbazone (198 and 69 mu g/cm(3), respectively). Derivatives of salicylaldehyde also impacted the strain morphology. In the media with salicylaldehyde- phenylhydrazone and salicylaldehyde-thiosemicarbazone, S. hygroscopicus CH-7 grew like large dispersive pellets with long twisted filaments that produced the highest yield of the antibiotics.en
dc.publisherAssociation of Chemical Engineers of Serbia
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/45001/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceHemijska industrija
dc.subjectglycerolen
dc.subjectsalicylaldehydeen
dc.subjectStreptomycesen
dc.subjectantibioticen
dc.subjectmorphologyen
dc.titleThe use of salicylaldehyde derivatives as a nitrogen source for antibiotic production by Streptomyces hygroscopicus CH-7en
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractВељковиц, Влада Б.; Златковиц, Милица З.; Цириц, Јован Т.; Илиц, Славица Б.; Константиновиц, Сандра С.; Гојгић Цвијовић, Гордана;
dc.citation.volume71
dc.citation.issue6
dc.citation.spage487
dc.citation.epage494
dc.citation.other71(6): 487-494
dc.citation.rankM23
dc.identifier.doi10.2298/HEMIND170124011K
dc.identifier.rcubConv_3859
dc.identifier.fulltexthttps://cer.ihtm.bg.ac.rs//bitstream/id/8530/2100.pdf
dc.identifier.scopus2-s2.0-85044395363
dc.identifier.wos000419973400004
dc.type.versionpublishedVersion


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