Stochastic Time Response of Adsorption-based Micro/Nanobiosensors with a Fluidic Reaction Chamber: the Influence of Mass Transfer
Abstract
An approximate model for efficient analysis of stochastic time response of microfluidic biosensors is presented, that considers a random AD process coupled with mass transfer (convection and diffusion) of target substance particles. The deterministic model of sensor response is also reviewed. We perform the analysis of the mass transfer influence on the kinetics and the steady-state value of the response calculated according to the two models (deterministic and stochastic). The results are presented for the sensors with different micro/nanoscale active surfaces. The comparison of the responses obtained by using the two models can be utilized to distinguish the cases in which the application of the deterministic model is justified from those in which the stochastic model is necessary. The presented findings enable more accurate interpretation of measurement results obtained by using micro/nanobiosensors.
Source:
Proceedings of the International Conference on Microelectronics, ICM, 2017, 127-130Publisher:
- Institute of Electrical and Electronics Engineers Inc.
Funding / projects:
- Micro- Nanosystems and Sensors for Electric Power and Process Industry and Environmental Protection (RS-32008)
- Serbian Academy of Sciences and Arts, Project F-150
DOI: 10.1109/MIEL.2017.8190084
ISSN: 2159-1660
WoS: 000427499000025
Scopus: 2-s2.0-85043596742
Collections
Institution/Community
IHTMTY - CONF AU - Jokić, Ivana AU - Đurić, Zoran G. AU - Radulović, Katarina AU - Frantlović, Miloš PY - 2017 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2101 AB - An approximate model for efficient analysis of stochastic time response of microfluidic biosensors is presented, that considers a random AD process coupled with mass transfer (convection and diffusion) of target substance particles. The deterministic model of sensor response is also reviewed. We perform the analysis of the mass transfer influence on the kinetics and the steady-state value of the response calculated according to the two models (deterministic and stochastic). The results are presented for the sensors with different micro/nanoscale active surfaces. The comparison of the responses obtained by using the two models can be utilized to distinguish the cases in which the application of the deterministic model is justified from those in which the stochastic model is necessary. The presented findings enable more accurate interpretation of measurement results obtained by using micro/nanobiosensors. PB - Institute of Electrical and Electronics Engineers Inc. C3 - Proceedings of the International Conference on Microelectronics, ICM T1 - Stochastic Time Response of Adsorption-based Micro/Nanobiosensors with a Fluidic Reaction Chamber: the Influence of Mass Transfer SP - 127 EP - 130 DO - 10.1109/MIEL.2017.8190084 ER -
@conference{ author = "Jokić, Ivana and Đurić, Zoran G. and Radulović, Katarina and Frantlović, Miloš", year = "2017", abstract = "An approximate model for efficient analysis of stochastic time response of microfluidic biosensors is presented, that considers a random AD process coupled with mass transfer (convection and diffusion) of target substance particles. The deterministic model of sensor response is also reviewed. We perform the analysis of the mass transfer influence on the kinetics and the steady-state value of the response calculated according to the two models (deterministic and stochastic). The results are presented for the sensors with different micro/nanoscale active surfaces. The comparison of the responses obtained by using the two models can be utilized to distinguish the cases in which the application of the deterministic model is justified from those in which the stochastic model is necessary. The presented findings enable more accurate interpretation of measurement results obtained by using micro/nanobiosensors.", publisher = "Institute of Electrical and Electronics Engineers Inc.", journal = "Proceedings of the International Conference on Microelectronics, ICM", title = "Stochastic Time Response of Adsorption-based Micro/Nanobiosensors with a Fluidic Reaction Chamber: the Influence of Mass Transfer", pages = "127-130", doi = "10.1109/MIEL.2017.8190084" }
Jokić, I., Đurić, Z. G., Radulović, K.,& Frantlović, M.. (2017). Stochastic Time Response of Adsorption-based Micro/Nanobiosensors with a Fluidic Reaction Chamber: the Influence of Mass Transfer. in Proceedings of the International Conference on Microelectronics, ICM Institute of Electrical and Electronics Engineers Inc.., 127-130. https://doi.org/10.1109/MIEL.2017.8190084
Jokić I, Đurić ZG, Radulović K, Frantlović M. Stochastic Time Response of Adsorption-based Micro/Nanobiosensors with a Fluidic Reaction Chamber: the Influence of Mass Transfer. in Proceedings of the International Conference on Microelectronics, ICM. 2017;:127-130. doi:10.1109/MIEL.2017.8190084 .
Jokić, Ivana, Đurić, Zoran G., Radulović, Katarina, Frantlović, Miloš, "Stochastic Time Response of Adsorption-based Micro/Nanobiosensors with a Fluidic Reaction Chamber: the Influence of Mass Transfer" in Proceedings of the International Conference on Microelectronics, ICM (2017):127-130, https://doi.org/10.1109/MIEL.2017.8190084 . .