Synthesis of vinyldihydropyran by cooperative catalysis
Abstract
Delta(5)-Unsaturated aldehydes with a suitably positioned allylic halide, or phosphate, leaving group undergo doubly-catalyzed cyclization to give dihydropyran derivatives. The cyclization proceeds under the synergetic action of diazabicycloundecene and Pd(PPh3)(4). This type of transformation was also accomplished with an aryl ketone.
Keywords:
dihydropyran / cooperative catalysis / cyclization / organopalladium reagentsSource:
Journal of the Serbian Chemical Society, 2016, 81, 12, 1335-1343Publisher:
- Serbian Chemical Soc, Belgrade
Projects:
DOI: 10.2298/JSC161102103V
ISSN: 0352-5139