Претраживање
Приказ резултата 1-3 од 3
Cholic acid derivatives as 1,2,4,5-tetraoxane carriers: Structure and antimalarial and antiproliferative activity
(American Chemical Society (ACS), 2000)
Cholic acid-derived 1,2,4,5-tetraoxanes were synthesized in order to explore the influence of steroid carrier on its antimalarial and antiproliferative activity in vitro. Starting with chiral ketones, cis and trans series ...
Tetraoxane antimalarials and their reaction with Fe(II)
(American Chemical Society (ACS), 2006)
Mixed tetraoxanes 5a and 13 synthesized from cholic acid and 4-oxocyclohexanecarboxylic acid were as active as artemisinin against chloroquine-susceptible, chloroquine-resistant, and multidrug-resistant Plasmodium falciparum ...
Mixed steroidal 1,2,4,5-tetraoxanes: Antimalarial and antimycobacterial activity
(American Chemical Society (ACS), 2002)
Mixed 1,2,4,5-tetraoxanes possessing simple spirocycloalkane and spirocholic acid-derived substituents were prepared and shown to have significantly higher in vitro antimalarial activity than bis-substituted tetraoxanes. ...