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Synthesis and pharmacological evaluation of novel tacrine derivatives as potential acetylcholinesterase inhibitors
(The Société de Chimie Thérapeutique (SCT) / French Medicinal Chemistry Society, 2021)
Alzheimer's disease (AD) is a progressive, neurodegenerative disorder characterized by deterioration of
cognitive skills and it is the most abundant form of dementia according to the World Health Organization
(WHO).1 ...
Novel multitarget tacrine derivatives: design and structure activity relationship
(European Federation for Medicinal chemistry and Chemical biology (EFMC), 2022)
Alzheimer's disease (AD) is a serious, neurodegenerative disease, characterized with a progressive loss of cognitive and behavioral functions leading to fatal outcome. Tacrine belongs to a class of cholinesterase ...