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Novel multitarget tacrine derivatives: design and structure activity relationship
(European Federation for Medicinal chemistry and Chemical biology (EFMC), 2022)
Alzheimer's disease (AD) is a serious, neurodegenerative disease, characterized with a progressive loss of cognitive and behavioral functions leading to fatal outcome. Tacrine belongs to a class of cholinesterase ...
Structure-activity relationship, docking analysis and ADME properties of newly designed, potent serotonin 5HT1a receptor ligands
(European Federation for Medicinal chemistry and Chemical biology (EFMC), 2022)
Serotonin 5HT1a receptors belongs to a class G-protein coupled receptors and it is widely recognized as one of the targets for treating neurological disorders such depression and schizophrenia. N-arylpiperazine structural ...