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Synthesis and Biological Activity of new 5-O-Benzyl-7-thiazolyl Isosteres of goniofufurone and 7-epi-goniofufurone
(Wiley, 2012)
Herein we report a total synthesis of two novel goniofufurone and 7-epi-goniofufurone isosteres bearing a 2-thiazolyl-4-amide moiety instead of the phenyl group at C-7, as well as O-benzyl instead of hydroxyl group at C-5.