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Fast profiling of protease specificity reveals similar substrate specificities for cathepsins K, L and S
(Wiley-Blackwell, Hoboken, 2015)
Proteases are important effectors of numerous physiological and pathological processes. Reliable determination of a protease's specificity is crucial to understand protease function and to develop activity-based probes and ...
Study of Simultaneous Radionuclide Sorption by Mixture Design Methodology
(American Chemical Society (ACS), 2015)
The problem of simultaneous removal of Co2+, Sr2+, and Cs+ ions from aqueous solutions was addressed using oxide, phosphate, and aluminosilicate materials from economical and abundant sources. Competition between cations ...
Rh catalyzed multicomponent tandem and one-pot reactions under hydroformylation conditions
(Elsevier, 2015)
The hydroformylation reaction represents one of the most important metal catalyzed bulk chemical manufacturing processes today. However, tremendous progress towards more complex molecules using tandem hydroformylation has ...
Biocompatible microemulsions of a model NSAID for skin delivery: A decisive role of surfactants in skin penetration/irritation profiles and pharmacokinetic performance
(Elsevier, 2015)
To elaborate the decisive role of surfactants in promotion of aceclofenac' skin absorption, potentially avoiding irritation, we developed non-ionic microemulsions varying natural or synthetic surfactants: sucrose esters ...
Parenteral nanoemulsions as promising carriers for brain delivery of risperidone: Design, characterization and in vivo pharmacokinetic evaluation
(Elsevier, 2015)
This paper describes design and evaluation of parenteral lecithin-based nanoemulsions intended for brain delivery of risperidone, a poorly water-soluble psychopharmacological drug. The nanoemulsions were prepared through ...
5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII
(Oxford : Pergamon-Elsevier Science Ltd, 2015)
Inhibitory activity of a congeneric set of 23 phenyl-substituted 5-phenyl-pyrazole-3-carboxylic acids toward human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms I, II, IX and XII was evaluated by a stopped-flow CO2 hydrase ...
Nonlinear frequency response analysis of forced periodic operation of non-isothermal CSTR with simultaneous modulation of inlet concentration and inlet temperature
(Oxford : Pergamon-Elsevier Science Ltd, 2015)
The nonlinear frequency response (NFR) method is applied for evaluation of possible improvement through simultaneous periodic modulation of two inputs of a non-isothermal continuously stirred tank reactor (CSTR) in which ...
Strong in Vitro Cytotoxic Potential of New Ruthenium-Cymene Complexes
(American Chemical Society (ACS), 2015)
Two p-cymenerutheniumchlorido complexes with thiourea derivative of 7-chloroquinoline (C1) and pyridine-3-imidazole (C2) were synthesized starting from [(eta(6)-p-cymene)RuCl2](2) and corresponding ligands. The structures ...
Analogy between momentum and heat transfer in liquid-solid fluidized beds
(Elsevier, 2015)
Wall-to-bed heat transfer in particulate fluidized beds of spherical particles was studied. Experiments were performed using spherical glass particles of 0.80-2.98 mm in diameter with water in a 25.4 mm I.D. copper tube ...
Visible light absorption of surface modified TiO2 powders with bidentate benzene derivatives
(Elsevier, 2015)
TiO2 powders with different specific surface area were prepared using reproducible, sol gel synthetic route and their ability to form hybrids with catechol and 5-amino salicylic acid was compared with the commercially ...