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Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa
dc.creator | Bukvicki, Danka | |
dc.creator | Ciric, Ana | |
dc.creator | Soković, Marina | |
dc.creator | Vannini, Lucia | |
dc.creator | Nissen, Lorenzo | |
dc.creator | Novaković, Miroslav | |
dc.creator | Vujisić, Ljubodrag V. | |
dc.creator | Asakawa, Yoshinori | |
dc.creator | Marin, Petar D. | |
dc.date.accessioned | 2019-01-30T17:49:26Z | |
dc.date.available | 2019-01-30T17:49:26Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1934-578X | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/1906 | |
dc.description.abstract | The chemical composition, antimicrobial and antiquorum sensing activity of the essential oil of Micromeria thymifolia (Scop.) Fritsch were investigated. Limonene, piperitone epoxide and piperitenone epoxide were found as the main constituents using a gas chromatography-mass spectrometry technique. In vitro antimicrobial activity of the oil was tested against six bacterial and seven fungal strains and high antimicrobial potential was noticed. Minimum inhibitory concentration varied from 0.031 mg/mL to 0.5 mg/mL for bacterial and 0.062 mg/mL to 0.5 mg/mL for fungal strains. The antiquorum properties of the essential oil were evaluated on Pseudomonas aeruginosa PAO1. The oil was tested at subMiC concentrations for anti-quorum sensing activity. The analyses on quorum-sensing functions have been carried out by evaluating twitching and swarming of bacterial cultures and the total amount of pyocyanin production produced by P. aeruginosa. This study showed that M thymifolia essential oil exhibited antiquorum sensing activity and may be used as an antipathogenic drug. | en |
dc.publisher | Natural Products Inc, Westerville | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173029/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173032/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS// | |
dc.relation | Department of Agricultural and Food Sciences, University of Bologna, Italy | |
dc.rights | openAccess | |
dc.source | Natural Product Communications | |
dc.subject | Micromeria thymifolia | en |
dc.subject | Essential oil | en |
dc.subject | Antimicrobial activity | en |
dc.subject | Antiquorum effect | en |
dc.subject | GC-MS | en |
dc.title | Micromeria thymifolia Essential Oil Suppresses Quorum-sensing Signaling in Pseudomonas aeruginosa | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Ваннини, Луциа; Буквицки, Данка; Цириц, Aна; Соковиц, Марина; Новаковић, Мирослав; Вујисиц, Љубодраг; Ниссен, Лорензо; Aсакаwа, Yосхинори; Марин, Петар Д.; | |
dc.citation.volume | 11 | |
dc.citation.issue | 12 | |
dc.citation.spage | 1903 | |
dc.citation.epage | 1906 | |
dc.citation.other | 11(12): 1903-1906 | |
dc.citation.rank | M23 | |
dc.identifier.pmid | 30508362 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_cherry_2374 | |
dc.identifier.fulltext | https://cer.ihtm.bg.ac.rs/bitstream/id/14700/1934578x1601101232.pdf | |
dc.identifier.wos | 000390975600032 | |
dc.type.version | publishedVersion |