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dc.creatorBolic, Bojana
dc.creatorMijuskovic, Ana
dc.creatorPopovic-Bijelic, Ana
dc.creatorNikolić-Kokić, Aleksandra
dc.creatorSpasić, Snežana
dc.creatorBlagojevic, Dusko
dc.creatorSpasic, Mihajlo B
dc.creatorSpasojević, Ivan
dc.date.accessioned2019-01-30T17:47:00Z
dc.date.available2019-01-30T17:47:00Z
dc.date.issued2015
dc.identifier.issn1089-8603
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1787
dc.description.abstractInteractions of hydrogen sulfide (HS-/H2S), a reducing signaling species, with superoxide dimutases (SOD) are poorly understood. We applied low-T EPR spectroscopy to examine the effects of HS-/H2S and superoxide radical anion (O-2(-)) on metallocenters of FeSOD, MnSOD, and CuZnSOD. HS-/H2S did not affect FeSOD, whereas active centers of MnSOD and CuZnSOD were open to this agent. Cu2+ was reduced to Cu1+, while manganese appears to be released from MnSOD active center. Untreated and O-2(-) treated FeSOD and MnSOD predominantly show 5 d-electron systems, i.e. Fe3+ and Mn2+. Our study provides new details on the mechanisms of (patho)physiological effects of HS-/H2S.en
dc.publisherAcademic Press Inc Elsevier Science, San Diego
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173014/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41005/RS//
dc.rightsrestrictedAccess
dc.sourceNitric Oxide-Biology and Chemistry
dc.subjectSuperoxide dismutaseen
dc.subjectEPRen
dc.subjectH2Sen
dc.subjectIronen
dc.subjectManganeseen
dc.subjectCopperen
dc.titleReactions of superoxide dismutases with HS-/H2S and superoxide radical anion: An in vitro EPR studyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСпасић, Снежана; Николиц-Кокиц, Aлександра; Благојевиц, Дуско; Спасојевиц, Иван; Болиц, Бојана; Мијусковиц, Aна; Поповиц-Бијелиц, Aна; Спасиц, Михајло Б;
dc.citation.volume51
dc.citation.spage19
dc.citation.epage23
dc.citation.other51: 19-23
dc.citation.rankM22
dc.description.otherAccepted version: [http://cer.ihtm.bg.ac.rs/handle/123456789/3187]
dc.identifier.pmid26436856
dc.identifier.doi10.1016/j.niox.2015.09.008
dc.identifier.rcubConv_3454
dc.identifier.scopus2-s2.0-84944719548
dc.identifier.wos000366065100003
dc.type.versionpublishedVersion


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