Приказ основних података о документу
Synthesis and antimicrobial activity of azepine and thiepine derivatives
dc.creator | Bozinovic, Nina | |
dc.creator | Novaković, Irena | |
dc.creator | Kostić Rajačić, Slađana | |
dc.creator | Opsenica, Igor | |
dc.creator | Šolaja, Bogdan | |
dc.date.accessioned | 2019-01-30T17:45:08Z | |
dc.date.available | 2019-01-30T17:45:08Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 0352-5139 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/1702 | |
dc.description.abstract | A series of new pyridobenzazepine and pyridobenzothiepine derivatives was synthesized by Pd-catalyzed formation of C-N and C-S bonds. All synthesized compounds were tested for their in vitro antimicrobial activity. The pyridobenzazepine derivatives showed better antibacterial and antifungal activity than the corresponding dipyridoazepine analogue. Among the synthesized azepines, derivative 8 displayed potent activity against the tested bacteria (MIC ranged 39-78 mu g mL(-1)), while azepine 12 showed promising antifungal activity (MIC ranged 156-313 mu g mL(-1)). The synthesized thiepine derivatives exhibited weak antibacterial activity, but showed pronounced antifungal activity. | en |
dc.publisher | Serbian Chemical Soc, Belgrade | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172008/RS// | |
dc.relation | Serbian Academy of Sciences and Arts | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Journal of the Serbian Chemical Society | |
dc.subject | azepines | en |
dc.subject | thiepines | en |
dc.subject | heterocycles | en |
dc.subject | palladium | en |
dc.subject | antibacterials | en |
dc.subject | antifungal | en |
dc.title | Synthesis and antimicrobial activity of azepine and thiepine derivatives | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Опсеница, Игор М; Солаја, Богдан A; Новаковић, Ирена; Бозиновиц, Нина; Костић Рајачић, Слађана; | |
dc.citation.volume | 80 | |
dc.citation.issue | 7 | |
dc.citation.spage | 839 | |
dc.citation.epage | 852 | |
dc.citation.other | 80(7): 839-852 | |
dc.citation.rank | M23 | |
dc.identifier.doi | 10.2298/JSC150116013B | |
dc.identifier.fulltext | https://cer.ihtm.bg.ac.rs//bitstream/id/8153/1700.pdf | |
dc.identifier.scopus | 2-s2.0-84938924652 | |
dc.identifier.wos | 000359326100001 | |
dc.type.version | publishedVersion |