Diarylheptanoids from Green Alder Bark and Their Potential for DNA Protection
dc.creator | Novaković, Miroslav | |
dc.creator | Stanković, Miroslava | |
dc.creator | Vučković, Ivan | |
dc.creator | Todorović, Nina | |
dc.creator | Trifunović, Snežana | |
dc.creator | Apostolovic, Danijela | |
dc.creator | Mandić, Boris | |
dc.creator | Veljić, Milan | |
dc.creator | Marin, Petar D. | |
dc.creator | Tešević, Vele | |
dc.creator | Vajs, Vlatka | |
dc.creator | Milosavljević, Slobodan | |
dc.date.accessioned | 2019-01-30T17:42:57Z | |
dc.date.available | 2019-01-30T17:42:57Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1612-1872 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/1596 | |
dc.description.abstract | Nine diarylheptanoids, 1-9, catechin (11), and a phenolic glucoside, 10, were isolated from the bark of green alder (Alnus viridis). Four of the isolated compounds, i.e., 2, 5, 8, 10, are new. The structures of 1-11 were determined on the basis of spectroscopic data. All isolated compounds were evaluated for their in vitro protective effects on chromosome aberrations in peripheral human lymphocytes using cytokinesis-block micronucleus (CBMN) assay. Almost all of them exerted a pronounced effect of decreasing DNA damage of human lymphocytes, acting stronger than the known synthetic protector amifostine. | en |
dc.publisher | Wiley-V C H Verlag Gmbh, Weinheim | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS// | |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/256716/EU// | |
dc.rights | restrictedAccess | |
dc.source | Chemistry & Biodiversity | |
dc.title | Diarylheptanoids from Green Alder Bark and Their Potential for DNA Protection | en |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.volume | 11 | |
dc.citation.issue | 6 | |
dc.citation.spage | 872 | |
dc.citation.epage | 885 | |
dc.citation.other | 11(6): 872-885 | |
dc.citation.rank | M22 | |
dc.identifier.pmid | 24934673 | |
dc.identifier.doi | 10.1002/cbdv.201300277 | |
dc.identifier.scopus | 2-s2.0-84902822329 | |
dc.identifier.wos | 000337726800003 | |
dc.type.version | publishedVersion |