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dc.creatorMladenović, Aleksandar R.
dc.creatorMijin, Dušan
dc.creatorDrmanić, Saša Ž.
dc.creatorVajs, Vlatka
dc.creatorJovanović, Vladislava M.
dc.creatorPetrović, Slobodan D.
dc.creatorAvramov Ivić, Milka
dc.date.accessioned2019-01-30T17:42:34Z
dc.date.available2019-01-30T17:42:34Z
dc.date.issued2014
dc.identifier.issn1040-0397
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1577
dc.description.abstractThe oxidative ability of donepezil, a frequently prescribed drug for the treatment of Alzheimer's disease is reported for the first time at a gold electrode. It was oxidized by cyclic voltammetry and determined by square wave voltammetry in phosphate buffer electrolyte. Electrochemical degradation of donepezil was carried out by long term potential cycling. The identification and characterization of the major product, isolated by preparative high performance liquid chromatography, was performed by high resolution mass spectrometry and 1D and 2D nuclear magnetic resonance spectroscopy. Donepezil hydroxy derivative was identified as the major electrochemical oxidation product from donepezil.en
dc.publisherWiley-Blackwell, Malden
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172013/RS//
dc.rightsrestrictedAccess
dc.sourceElectroanalysis
dc.subjectCyclic voltammetryen
dc.subjectDonepezilen
dc.subjectGold electrodeen
dc.subjectOxidationen
dc.subjectSquare wave voltammetryen
dc.titleElectrochemical Oxidation of Donepezil and Its Voltammetric Determination at Gold Electrodeen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЈовановић, Владислава; Петровић, Слободан Д.; Aврамов Ивић, Милка; Вајс, Влатка Е.; Мијин, Дусан З.; Младеновиц, Aлександар Р.; Дрманиц, Саса З.;
dc.citation.volume26
dc.citation.issue5
dc.citation.spage893
dc.citation.epage897
dc.citation.other26(5): 893-897
dc.citation.rankM22
dc.identifier.doi10.1002/elan.201400034
dc.identifier.rcubConv_3150
dc.identifier.scopus2-s2.0-84900331905
dc.identifier.wos000335997600001
dc.type.versionpublishedVersion


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