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dc.creatorPejić, Nataša
dc.creatorBlagojević, Slavica
dc.creatorSarap, Natasa B.
dc.creatorMaksimović, Jelena
dc.creatorAnić, Slobodan
dc.creatorČupić, Željko
dc.creatorKolar-Anić, Ljiljana
dc.date.accessioned2019-01-30T17:41:44Z
dc.date.available2019-01-30T17:41:44Z
dc.date.issued2014
dc.identifier.issn0018-019X
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1539
dc.description.abstractPerturbation of the BrayLiebhafsky non-oscillating subsystem (mixture of KIO3 and H2SO4), i.e., Dushman reaction (DR), by piroxicam (PX), was observed in an open reactor, i.e., in the continuously fed well-stirred tank reactor (CSTR). Monitoring the response of DR to perturbations by different concentrations of PX allows developing a simple procedure for quantitative determination of this analyte in both bulk drug and pharmaceutical preparation (injection). A tentative perturbation mechanism of PX action on the DR matrix, based on a kinetic scheme that was suggested by Agreda etal., is proposed. The PX reactivity in DR has been generally related to the reaction of PX with hypoiodous acid (HIO) present in the matrix.en
dc.publisherWiley-V C H Verlag Gmbh, Weinheim
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172015/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43009/RS//
dc.rightsrestrictedAccess
dc.sourceHelvetica Chimica Acta
dc.subjectDushman reactionen
dc.subjectKinetic methodsen
dc.subjectPerturbationsen
dc.subjectPiroxicamen
dc.titlePerturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculationsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЧупић, Жељко; Aниц, Слободан Р.; Пејиц, Натаса Д.; Максимовиц, Јелена П.; Сарап, Натаса Б.; Колар-Aниц, Љиљана З.; Благојевиц, Славица М.;
dc.citation.volume97
dc.citation.issue1
dc.citation.spage47
dc.citation.epage55
dc.citation.other97(1): 47-55
dc.citation.rankM23
dc.identifier.doi10.1002/hlca.201300109
dc.identifier.rcubConv_3112
dc.identifier.scopus2-s2.0-84892760651
dc.identifier.wos000330865900004
dc.type.versionpublishedVersion


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