Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives

2014
Authors
Šekularac, Gavrilo
Nikolić, Jasmina B.

Petrović, Predrag
Bugarski, Branko

Durovic, Boban
Drmanić, Saša Ž.
Article (Published version)
Metadata
Show full item recordAbstract
The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods. Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungus. The antioxidative activity of the synthesized compounds was also determined. Some of the compounds showed significant activity against the selected strains of microorganisms and antioxidative activity.
Keywords:
isatin derivatives / Schiff bases / antimicrobial activity / antioxidative activitySource:
Journal of the Serbian Chemical Society, 2014, 79, 11, 1347-1354Publisher:
- Serbian Chemical Society
Funding / projects:
- Study of the Synthesis, Structure and Activity of Natural and Synthetic Organic Compounds (RS-172013)
- Novel encapsulation and enzyme technologies for designing of new biocatalysts and biologically active compounds targeting enhancement of food quality, safety and competitiveness (RS-46010)
DOI: 10.2298/JSC140709084S
ISSN: 0352-5139
WoS: 000346879000002
Scopus: 2-s2.0-84986882191
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IHTMTY - JOUR AU - Šekularac, Gavrilo AU - Nikolić, Jasmina B. AU - Petrović, Predrag AU - Bugarski, Branko AU - Durovic, Boban AU - Drmanić, Saša Ž. PY - 2014 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/1477 AB - The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods. Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungus. The antioxidative activity of the synthesized compounds was also determined. Some of the compounds showed significant activity against the selected strains of microorganisms and antioxidative activity. PB - Serbian Chemical Society T2 - Journal of the Serbian Chemical Society T1 - Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives VL - 79 IS - 11 SP - 1347 EP - 1354 DO - 10.2298/JSC140709084S ER -
@article{ author = "Šekularac, Gavrilo and Nikolić, Jasmina B. and Petrović, Predrag and Bugarski, Branko and Durovic, Boban and Drmanić, Saša Ž.", year = "2014", abstract = "The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods. Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungus. The antioxidative activity of the synthesized compounds was also determined. Some of the compounds showed significant activity against the selected strains of microorganisms and antioxidative activity.", publisher = "Serbian Chemical Society", journal = "Journal of the Serbian Chemical Society", title = "Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives", volume = "79", number = "11", pages = "1347-1354", doi = "10.2298/JSC140709084S" }
Šekularac, G., Nikolić, J. B., Petrović, P., Bugarski, B., Durovic, B.,& Drmanić, S. Ž.. (2014). Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives. in Journal of the Serbian Chemical Society Serbian Chemical Society., 79(11), 1347-1354. https://doi.org/10.2298/JSC140709084S
Šekularac G, Nikolić JB, Petrović P, Bugarski B, Durovic B, Drmanić SŽ. Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives. in Journal of the Serbian Chemical Society. 2014;79(11):1347-1354. doi:10.2298/JSC140709084S .
Šekularac, Gavrilo, Nikolić, Jasmina B., Petrović, Predrag, Bugarski, Branko, Durovic, Boban, Drmanić, Saša Ž., "Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives" in Journal of the Serbian Chemical Society, 79, no. 11 (2014):1347-1354, https://doi.org/10.2298/JSC140709084S . .