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Analysis of human exhaled breath in a population of young volunteers

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2014
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Autori
Zarić, Božidarka
Petrović, Srđan
Bjekic, Milan
Rajic, Ivana
Popović, Aleksandar R.
Đorđević, Dragana
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentu
Apstrakt
Analysis of volatile organic compounds (VOCs) in human breath can provide information about the current physiological state of an individual, such as clinical conditions and exposure to exogenous pollutants. The blood-borne VOCs present in exhaled breath offer the possibility of exploring physiological and pathological processes in a noninvasive way. However, the field of exhaled breath analysis is still in its infancy. We undertook this study in order to define inter-individual variation and common compounds in breath VOCs of 48 young human volunteers. Alveolar breath samples were analyzed by automated thermal desorption, gas chromatography with flame ionization detector (FID) and electron capture detector (ECD) using SUPELCO standards with 66 compounds. Predominant compounds in the alveolar breath of analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene, 1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects). Isopropyl alcohol, propylene, acetone, ethanol ...were found as well. We detected substituted compounds in exhaled breath.

Ključne reči:
alveolar breath / volatile organic compounds / exhaled breath condensate / gas chromatography
Izvor:
Archives of Biological Sciences, 2014, 66, 4, 1529-1538
Izdavač:
  • Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd
Finansiranje / projekti:
  • Proučavanje fizičkohemijskih i biohemijskih procesa u životnoj sredini koji utiču na zagađenje i istraživanje mogućnosti za minimiziranje posledica (RS-172001)

DOI: 10.2298/ABS1404529Z

ISSN: 0354-4664

WoS: 000346477900027

Scopus: 2-s2.0-84921629917
[ Google Scholar ]
4
4
URI
https://cer.ihtm.bg.ac.rs/handle/123456789/1475
Kolekcije
  • Radovi istraživača / Researchers' publications
Institucija/grupa
IHTM
TY  - JOUR
AU  - Zarić, Božidarka
AU  - Petrović, Srđan
AU  - Bjekic, Milan
AU  - Rajic, Ivana
AU  - Popović, Aleksandar R.
AU  - Đorđević, Dragana
PY  - 2014
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1475
AB  - Analysis of volatile organic compounds (VOCs) in human breath can provide information about the current physiological state of an individual, such as clinical conditions and exposure to exogenous pollutants. The blood-borne VOCs present in exhaled breath offer the possibility of exploring physiological and pathological processes in a noninvasive way. However, the field of exhaled breath analysis is still in its infancy. We undertook this study in order to define inter-individual variation and common compounds in breath VOCs of 48 young human volunteers. Alveolar breath samples were analyzed by automated thermal desorption, gas chromatography with flame ionization detector (FID) and electron capture detector (ECD) using SUPELCO standards with 66 compounds. Predominant compounds in the alveolar breath of analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene, 1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects). Isopropyl alcohol, propylene, acetone, ethanol were found as well. We detected substituted compounds in exhaled breath.
PB  - Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd
T2  - Archives of Biological Sciences
T1  - Analysis of human exhaled breath in a population of young volunteers
VL  - 66
IS  - 4
SP  - 1529
EP  - 1538
DO  - 10.2298/ABS1404529Z
ER  - 
@article{
author = "Zarić, Božidarka and Petrović, Srđan and Bjekic, Milan and Rajic, Ivana and Popović, Aleksandar R. and Đorđević, Dragana",
year = "2014",
abstract = "Analysis of volatile organic compounds (VOCs) in human breath can provide information about the current physiological state of an individual, such as clinical conditions and exposure to exogenous pollutants. The blood-borne VOCs present in exhaled breath offer the possibility of exploring physiological and pathological processes in a noninvasive way. However, the field of exhaled breath analysis is still in its infancy. We undertook this study in order to define inter-individual variation and common compounds in breath VOCs of 48 young human volunteers. Alveolar breath samples were analyzed by automated thermal desorption, gas chromatography with flame ionization detector (FID) and electron capture detector (ECD) using SUPELCO standards with 66 compounds. Predominant compounds in the alveolar breath of analyzed subjects are ethylbenzene, 1-ethyl-4-methylbenzene, 1,2,4-trimethylbenzene and 1,3,5-trimethylbenzene (over 50% of the subjects). Isopropyl alcohol, propylene, acetone, ethanol were found as well. We detected substituted compounds in exhaled breath.",
publisher = "Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd",
journal = "Archives of Biological Sciences",
title = "Analysis of human exhaled breath in a population of young volunteers",
volume = "66",
number = "4",
pages = "1529-1538",
doi = "10.2298/ABS1404529Z"
}
Zarić, B., Petrović, S., Bjekic, M., Rajic, I., Popović, A. R.,& Đorđević, D.. (2014). Analysis of human exhaled breath in a population of young volunteers. in Archives of Biological Sciences
Inst Bioloska Istrazivanja Sinisa Stankovic, Beograd., 66(4), 1529-1538.
https://doi.org/10.2298/ABS1404529Z
Zarić B, Petrović S, Bjekic M, Rajic I, Popović AR, Đorđević D. Analysis of human exhaled breath in a population of young volunteers. in Archives of Biological Sciences. 2014;66(4):1529-1538.
doi:10.2298/ABS1404529Z .
Zarić, Božidarka, Petrović, Srđan, Bjekic, Milan, Rajic, Ivana, Popović, Aleksandar R., Đorđević, Dragana, "Analysis of human exhaled breath in a population of young volunteers" in Archives of Biological Sciences, 66, no. 4 (2014):1529-1538,
https://doi.org/10.2298/ABS1404529Z . .

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