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dc.creatorBjelaković, Mira
dc.creatorKop, Tatjana
dc.creatorVajic, Marina
dc.creatorDordevic, Jelena
dc.creatorMilić, Dragana
dc.date.accessioned2019-01-30T17:40:16Z
dc.date.available2019-01-30T17:40:16Z
dc.date.issued2014
dc.identifier.issn0040-4020
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1471
dc.description.abstractThe present study reports the synthesis, spectral characterization, self-assembly properties, and preliminary in vitro study of antioxidant capacity of two triple covalent hybrids consisting of fullerene C-60, peptide, and steroidal moiety. Previously synthesized fulleropyrrolidinic acid and pregnenolone were connected by peptide linker using a multistep DCC/DMAP and/or EDC/HOBT esterification/amidation procedure. The hybrids were characterized by comparative analysis of spectroscopic data obtained from FUR, UV-vis, HRMS, and extensive NMR experiments (H-1, C-13, COSY, HSQC, and HMBC). The self-assembling properties and morphology of triads samples prepared by drop-drying method were examined by scanning electron microscopy (SEM). Preliminary in vitro antioxidant activity was studied by Ferrous ion Oxidation-Xylenol orange (FOX) method.en
dc.publisherPergamon-Elsevier Science Ltd, Oxford
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172002/RS//
dc.rightsrestrictedAccess
dc.sourceTetrahedron
dc.subjectFullerene-peptide-steroid hybridsen
dc.subjectDCC/DMAPen
dc.subjectEDC/HOBTen
dc.subjectSEMen
dc.subjectAntioxidant activityen
dc.titleDesign, synthesis, and characterization of fullerene-peptide-steroid covalent hybridsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractДордевиц, Јелена; Бјелаковић, Мира; Вајиц, Марина; Коп, Татјана; Милиц, Драгана Р;
dc.citation.volume70
dc.citation.issue45
dc.citation.spage8564
dc.citation.epage8570
dc.citation.other70(45): 8564-8570
dc.citation.rankM22
dc.identifier.doi10.1016/j.tet.2014.09.070
dc.identifier.rcubConv_3256
dc.identifier.scopus2-s2.0-84907971389
dc.identifier.wos000345815100015
dc.type.versionpublishedVersion


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