Show simple item record

dc.creatorBondžić, Aleksandra M.
dc.creatorLazarević-Pašti, Tamara D.
dc.creatorBondžić, Bojan
dc.creatorČolović, Mirjana B.
dc.creatorJadranin, Milka
dc.creatorVasić, Vesna M.
dc.date.accessioned2019-01-30T17:36:38Z
dc.date.available2019-01-30T17:36:38Z
dc.date.issued2013
dc.identifier.issn1144-0546
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1293
dc.description.abstractThe aim of the present paper was to investigate the reaction of quercetin, the flavonol very often used as a dietary supplement, with [AuCl4](-) ions. The reaction was studied spectrophotometrically using the equimolar solutions in 1 : 1 water-methanol at pH similar to 2. The spectrophotometric data indicated the formation of the products with an absorption maximum at 295 nm in all cases, characteristic of the oxidized forms of quercetin. HPLC coupled with DAD and LC-MS analysis of the reaction products suggested that the oxidation of quercetin resulted in the generation of similar metabolites including quinone and various oxidized quercetin-solvent adducts. In addition, cyclic voltammetric measurements confirmed that under applied experimental conditions, the reduction of Au(III) to Au(0) took place. The reduction species in the reaction mixture were Au(III) ions, while Au(I) disproportionates back to Au(III) and Au(0). The newly generated Au(III) ions further oxidized 3'-4'-dihydroxy groups of quercetin adducts obtained after first 2e(-) oxidation, giving the final reaction products. Based on the identification of reaction products, the reaction mechanism for the oxidation of quercetin in the presence of Au(III) which involves two 2e(-) transfer processes was proposed.en
dc.publisherRoyal Soc Chemistry, Cambridge
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172023/RS//
dc.rightsrestrictedAccess
dc.sourceNew Journal of Chemistry
dc.titleInvestigation of reaction between quercetin and Au(III) in acidic media: mechanism and identification of reaction productsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractВасиц, Весна М.; Лазаревиц-Пасти, Тамара Д.; Бондзиц, Aлександра М.; Бонджић, Бојан; Цоловиц, Мирјана Б.; Јадранин, Милка;
dc.citation.volume37
dc.citation.issue4
dc.citation.spage901
dc.citation.epage908
dc.citation.other37(4): 901-908
dc.citation.rankM21
dc.identifier.doi10.1039/c2nj40742f
dc.identifier.rcubConv_2942
dc.identifier.scopus2-s2.0-84878039502
dc.identifier.wos000316225300008
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record