Show simple item record

dc.creatorMiladinovic, Dragoljub L.
dc.creatorIlic, Budimir S.
dc.creatorMihajilov-Krstev, Tatjana M.
dc.creatorNikolic, Dejan M.
dc.creatorCvetković, Olga
dc.creatorMarković, Marija S.
dc.creatorMiladinovic, Ljiljana C.
dc.date.accessioned2019-01-30T17:36:00Z
dc.date.available2019-01-30T17:36:00Z
dc.date.issued2013
dc.identifier.issn1934-578X
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1265
dc.description.abstractThe composition and antimicrobial activity of the essential oil of Heracleum sibiricum L. (Apiaceae) was studied. The aerial part of plant was hydro-distilled and chemical composition of the essential oil was analyzed by GC and GC-MS. Forty-six compounds, corresponding to 95.12% of the total oil, were identified. Esters represented the major chemical class (69.55%) while the main constituents were octyl butanoate (36.82%), hexyl butanoate (16.08%), 1-octanol (13.62%) and octyl hexanoate (8.10%). Antibacterial activity of the essential oil and reference antibiotics against nine bacterial strains was tested by the broth microdilution method. The results of the bioassays showed that essential oil had slight antimicrobial activities against all tested microorganisms (MIC and MBC values were in the range of 2431.2 to 9724.8 mu g/mL). Reference antibiotics were active in concentrations between 0.5 and 16.0 mu g/mL. The results confirm that Gram-positive bacteria were more susceptible to the essential oil of H. sibiricum, in comparison with Gram-negative bacteria.en
dc.publisherNatural Product Incorporation
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/171025/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/176006/RS//
dc.rightsrestrictedAccess
dc.sourceNatural Product Communications
dc.subjectHeracleum sibiricumen
dc.subjectEssential oilen
dc.subjectAntibacterial activityen
dc.titleAntibacterial Activity of the Essential Oil of Heracleum sibiricumen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМихајилов-Крстев, Татјана М.; Цветковић, Олга; Марковиц, Марија С.; Николиц, Дејан М.; Миладиновиц, Љиљана Ц.; Илиц, Будимир С.; Миладиновиц, Драгољуб Л.;
dc.citation.volume8
dc.citation.issue9
dc.citation.spage1309
dc.citation.epage1311
dc.citation.other8(9): 1309-1311
dc.citation.rankM23
dc.identifier.pmid24273873
dc.identifier.rcubConv_3069
dc.identifier.scopus2-s2.0-84886810474
dc.identifier.wos000326858000031
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record