CER - Central Repository
Institute of Chemistry, Technology and Metallurgy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   CER
  • IHTM
  • Radovi istraživača / Researchers' publications
  • View Item
  •   CER
  • IHTM
  • Radovi istraživača / Researchers' publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Antibacterial Activity of the Essential Oil of Heracleum sibiricum

Authorized Users Only
2013
Authors
Miladinovic, Dragoljub L.
Ilic, Budimir S.
Mihajilov-Krstev, Tatjana M.
Nikolic, Dejan M.
Cvetković, Olga
Marković, Marija S.
Miladinovic, Ljiljana C.
Article (Published version)
Metadata
Show full item record
Abstract
The composition and antimicrobial activity of the essential oil of Heracleum sibiricum L. (Apiaceae) was studied. The aerial part of plant was hydro-distilled and chemical composition of the essential oil was analyzed by GC and GC-MS. Forty-six compounds, corresponding to 95.12% of the total oil, were identified. Esters represented the major chemical class (69.55%) while the main constituents were octyl butanoate (36.82%), hexyl butanoate (16.08%), 1-octanol (13.62%) and octyl hexanoate (8.10%). Antibacterial activity of the essential oil and reference antibiotics against nine bacterial strains was tested by the broth microdilution method. The results of the bioassays showed that essential oil had slight antimicrobial activities against all tested microorganisms (MIC and MBC values were in the range of 2431.2 to 9724.8 mu g/mL). Reference antibiotics were active in concentrations between 0.5 and 16.0 mu g/mL. The results confirm that Gram-positive bacteria were more susceptible to the ...essential oil of H. sibiricum, in comparison with Gram-negative bacteria.

Keywords:
Heracleum sibiricum / Essential oil / Antibacterial activity
Source:
Natural Product Communications, 2013, 8, 9, 1309-1311
Publisher:
  • Natural Product Incorporation
Funding / projects:
  • The electrical breakdown of gases, surface processes and applications (RS-171025)
  • Geochemical investigations of sedimentary rocks - fossil fuels and environmental pollutants (RS-176006)

ISSN: 1934-578X

PubMed: 24273873

WoS: 000326858000031

Scopus: 2-s2.0-84886810474
[ Google Scholar ]
14
10
Handle
https://hdl.handle.net/21.15107/rcub_cer_1265
URI
https://cer.ihtm.bg.ac.rs/handle/123456789/1265
Collections
  • Radovi istraživača / Researchers' publications
Institution/Community
IHTM
TY  - JOUR
AU  - Miladinovic, Dragoljub L.
AU  - Ilic, Budimir S.
AU  - Mihajilov-Krstev, Tatjana M.
AU  - Nikolic, Dejan M.
AU  - Cvetković, Olga
AU  - Marković, Marija S.
AU  - Miladinovic, Ljiljana C.
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1265
AB  - The composition and antimicrobial activity of the essential oil of Heracleum sibiricum L. (Apiaceae) was studied. The aerial part of plant was hydro-distilled and chemical composition of the essential oil was analyzed by GC and GC-MS. Forty-six compounds, corresponding to 95.12% of the total oil, were identified. Esters represented the major chemical class (69.55%) while the main constituents were octyl butanoate (36.82%), hexyl butanoate (16.08%), 1-octanol (13.62%) and octyl hexanoate (8.10%). Antibacterial activity of the essential oil and reference antibiotics against nine bacterial strains was tested by the broth microdilution method. The results of the bioassays showed that essential oil had slight antimicrobial activities against all tested microorganisms (MIC and MBC values were in the range of 2431.2 to 9724.8 mu g/mL). Reference antibiotics were active in concentrations between 0.5 and 16.0 mu g/mL. The results confirm that Gram-positive bacteria were more susceptible to the essential oil of H. sibiricum, in comparison with Gram-negative bacteria.
PB  - Natural Product Incorporation
T2  - Natural Product Communications
T1  - Antibacterial Activity of the Essential Oil of Heracleum sibiricum
VL  - 8
IS  - 9
SP  - 1309
EP  - 1311
UR  - https://hdl.handle.net/21.15107/rcub_cer_1265
ER  - 
@article{
author = "Miladinovic, Dragoljub L. and Ilic, Budimir S. and Mihajilov-Krstev, Tatjana M. and Nikolic, Dejan M. and Cvetković, Olga and Marković, Marija S. and Miladinovic, Ljiljana C.",
year = "2013",
abstract = "The composition and antimicrobial activity of the essential oil of Heracleum sibiricum L. (Apiaceae) was studied. The aerial part of plant was hydro-distilled and chemical composition of the essential oil was analyzed by GC and GC-MS. Forty-six compounds, corresponding to 95.12% of the total oil, were identified. Esters represented the major chemical class (69.55%) while the main constituents were octyl butanoate (36.82%), hexyl butanoate (16.08%), 1-octanol (13.62%) and octyl hexanoate (8.10%). Antibacterial activity of the essential oil and reference antibiotics against nine bacterial strains was tested by the broth microdilution method. The results of the bioassays showed that essential oil had slight antimicrobial activities against all tested microorganisms (MIC and MBC values were in the range of 2431.2 to 9724.8 mu g/mL). Reference antibiotics were active in concentrations between 0.5 and 16.0 mu g/mL. The results confirm that Gram-positive bacteria were more susceptible to the essential oil of H. sibiricum, in comparison with Gram-negative bacteria.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Antibacterial Activity of the Essential Oil of Heracleum sibiricum",
volume = "8",
number = "9",
pages = "1309-1311",
url = "https://hdl.handle.net/21.15107/rcub_cer_1265"
}
Miladinovic, D. L., Ilic, B. S., Mihajilov-Krstev, T. M., Nikolic, D. M., Cvetković, O., Marković, M. S.,& Miladinovic, L. C.. (2013). Antibacterial Activity of the Essential Oil of Heracleum sibiricum. in Natural Product Communications
Natural Product Incorporation., 8(9), 1309-1311.
https://hdl.handle.net/21.15107/rcub_cer_1265
Miladinovic DL, Ilic BS, Mihajilov-Krstev TM, Nikolic DM, Cvetković O, Marković MS, Miladinovic LC. Antibacterial Activity of the Essential Oil of Heracleum sibiricum. in Natural Product Communications. 2013;8(9):1309-1311.
https://hdl.handle.net/21.15107/rcub_cer_1265 .
Miladinovic, Dragoljub L., Ilic, Budimir S., Mihajilov-Krstev, Tatjana M., Nikolic, Dejan M., Cvetković, Olga, Marković, Marija S., Miladinovic, Ljiljana C., "Antibacterial Activity of the Essential Oil of Heracleum sibiricum" in Natural Product Communications, 8, no. 9 (2013):1309-1311,
https://hdl.handle.net/21.15107/rcub_cer_1265 .

DSpace software copyright © 2002-2015  DuraSpace
About CeR – Central Repository | Send Feedback

re3dataOpenAIRERCUB
 

 

All of DSpaceInstitutions/communitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About CeR – Central Repository | Send Feedback

re3dataOpenAIRERCUB