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dc.creatorAntonijevic-Nikolic, Mirjana
dc.creatorAntić Stanković, Jelena
dc.creatorTanasković, Slađana B.
dc.creatorKorabik, Maria J.
dc.creatorGojgić-Cvijović, Gordana
dc.creatorVuckovic, Gordana
dc.date.accessioned2019-01-30T17:35:52Z
dc.date.available2019-01-30T17:35:52Z
dc.date.issued2013
dc.identifier.issn0022-2860
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1259
dc.description.abstractNew cationic Cu(II) complexes with N, N', N '', N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and aliphatic dicarboxylic acids: pentanedioic (glutaric acid = glutH(2)), hexanedioic acid (adipic acid = adipH(2)) and decanedioic acid (sebacic acid = sebH(2)) of general formula [Cu-4(L)(tpmc)(2)] (ClO4)(6)center dot xH(2)O, L = glut, x = 2; L = adip, x = 7; L = seb, x = 6 were isolated. Their composition and charges are proposed based on elemental analyses and molar conductivity measurements. By the comparison of their UV-Vis, reflectance, FTIR and EPR spectral data, CV and SQUID magnetic measurements, with those for the complex with butanedioic acid (succinic acid = succH(2)) of known molecular structure and analysis of LC/MS spectra, geometry with two [Cu(2)tpmc](4) units bridged by dicarboxylate dianion engaging all oxygens is proposed. Within units, Cu(II) ions are also bridged with -N- portion of cyclam ring. All four complexes were screened to in vitro antimicrobial and cytotoxic activity along with free primary and secondary ligands, Cu(II) salt and solvent controls. Detected antibacterial and cytotoxic activity for the complexes was enhanced in most cases than the corresponding controls.en
dc.publisherElsevier
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172014/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175011/RS//
dc.relationPolish National Science Centre - NN204 198240
dc.rightsrestrictedAccess
dc.sourceJournal of Molecular Structure
dc.subjectCopper(II) complexesen
dc.subjectOctaazamacrocycleen
dc.subjectAliphatic dicarboxylatesen
dc.subjectantibacterial and cytotoxic activityen
dc.subjectMagnetic propertiesen
dc.titlePreparation, characterisation and study of in vitro biologically active azamacrocyclic Cu(II) dicarboxylate complexesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractВуцковиц, Гордана; Корабик, Мариа Ј.; Гојгић Цвијовић, Гордана; Танасковић, Слађана Б.; Aнтиц-Станковиц, Јелена; Aнтонијевиц-Николиц, Мирјана;
dc.citation.volume1054
dc.citation.spage297
dc.citation.epage306
dc.citation.other1054: 297-306
dc.citation.rankM23
dc.identifier.doi10.1016/j.molstruc.2013.10.006
dc.identifier.rcubConv_3078
dc.identifier.scopus2-s2.0-84886104454
dc.identifier.wos000327921100039
dc.type.versionpublishedVersion


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