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Određivanje derivata amfetamina i primena u analizi humanog urina na elektrodi od zlata

dc.creatorNevescanin, Marina M.
dc.creatorAvramov Ivić, Milka
dc.creatorPetrović, Slobodan D.
dc.creatorMijin, Dušan
dc.creatorStevic, Sonja N. Banovic
dc.creatorJovanović, Vladislava M.
dc.date.accessioned2019-01-30T17:35:42Z
dc.date.available2019-01-30T17:35:42Z
dc.date.issued2013
dc.identifier.issn0352-5139
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/1252
dc.description.abstractThe catalytic abilities of a gold electrode were tested for the quantitative determination of amphetamine (A) and 3,4-methylenedioxy-N-methylamphetamine (MDMA) standards by their oxidation using cyclic voltammetry (CV). The values of the oxidative currents of A and MDMA standards at 0.80 V vs. SCE in 0.05 M NaHCO3 at a scan rate of 50 mV s-1 were linear functions of the concentration in range of 110.9-258.9 μM and 38.7-229.2 μM, respectively. Square wave voltammetry (SWV) revealed a linear increase of current with the concentration of MDMA (range 30.9-91.6 μM), which enabled the quantitative determination of amphetamine derivates. SWV analysis was also successfully performed in spiked urine samples. A and MDMA in the presence of sucrose and as a content in illegally produced tablets were also determined. The voltammetric determinations of A and MDMA derivatives using CV and SWV at gold a electrode are rapid, selective and simple procedures and their accuracy was confirmed with a reference method, high performance liquid chromatography (HPLC). The analysis of spiked urine samples offers an additional possibility for the rapid detection of A and MDMA in human urine.en
dc.description.abstractKatalitička svojstva elektrode od zlata su testirana za kvantitativno određivanje amfetamina (A) i 3,4-metilendioksi-N-metilamfetamina (MDMA) standarda. Elektroksidacija A i MDMA je praćena cikličnom voltametrijom (CV). Vrednost oksidativnog pika A i MDMA standarda je linearna funkcija koncentracija u opsegu 110,9-258,9 μM (A) i 38,7-229,2 μM (MDMA). Voltametrija sa pravougaonim impulsima (SWV) je pokazala linearnu zavisnost struja od koncentracija za MDMA standard (u opsegu: 30,9-91,6 μM) kao i u spajkovanim uzorcima humanog urina. Uspešno je analiziran i sadržaj A i MDMA u ilegalno proizvedenim tabletama. Voltametrijsko određivanje A i MDMA derivata uz pomoć CV i SWV na elektrodi od zlata je brza, selektivna i jednostavna procedura. Analiza spajkovanih uzoraka urina nudi dodatnu mogućnost za brzu detekciju A i MDMA u humanom urinu.sr
dc.publisherSerbian Chemical Society
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172013/RS//
dc.rightsopenAccess
dc.sourceJournal of the Serbian Chemical Society
dc.subjectamphetamine derivativesen
dc.subjectcyclic voltammetryen
dc.subjectsquare wave voltammetryen
dc.subjectspiked urine samplesen
dc.titleThe use of a gold electrode for the determination of amphetamine derivatives and application to their analysis in human urineen
dc.titleOdređivanje derivata amfetamina i primena u analizi humanog urina na elektrodi od zlatasr
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractНевесцанин, Марина М.; Стевиц, Соња Н. Бановиц; Мијин, Дусан З.; Јовановић, Владислава; Aврамов Ивић, Милка; Петровић, Слободан Д.; Одређивање деривата амфетамина и примена у анализи хуманог урина на електроди од злата; Одређивање деривата амфетамина и примена у анализи хуманог урина на електроди од злата;
dc.citation.volume78
dc.citation.issue9
dc.citation.spage1373
dc.citation.epage1385
dc.citation.other78(9): 1373-1385
dc.citation.rankM23
dc.identifier.doi10.2298/JSC121228032N
dc.identifier.rcubConv_3055
dc.identifier.fulltexthttp://cer.ihtm.bg.ac.rs//bitstream/id/7762/1250.pdf
dc.identifier.scopus2-s2.0-84885100340
dc.identifier.wos000326199200009
dc.type.versionpublishedVersion


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