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dc.creatorSvirčev, Zorica
dc.creatorDrobac, Damjana
dc.creatorTokodi, Nada
dc.creatorVidović, Milka
dc.creatorSimeunovic, Jelica
dc.creatorMiladinov-Mikov, Marica
dc.creatorBaltic, Vladimir
dc.date.accessioned2019-01-30T17:34:35Z
dc.date.available2019-01-30T17:34:35Z
dc.date.issued2013
dc.identifier.issn1059-0501
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/1197
dc.description.abstractToday, the occurrence of harmful cyanobacterial blooms is a common phenomenon and a potential global health problem. Cyanobacteria can produce metabolites highly toxic to humans. More than 80% of reservoirs used for water supply in Central Serbia have bloomed over the past 80years. A 10-year epidemiological study showed a significant increase in the incidence of primary liver cancer (PLC) in the regions where water from the blooming reservoirs was used for human consumption. At the same time, no correlation was found between the incidence of PLC and other risk factors, such as cirrhosis and hepatitis viruses. Given the strong association with PLC induction and various known possible mechanisms of carcinogenic action, it is highly possible that, cyanotoxinsacting as initiator and promotermay be the major risk factor that acts synergistically with other risk factors to cause increased incidence of PLC. However, at present, it is still not certain whether cyanotoxins alone were sufficient to induce PLC. Therefore, additional assessment of the health risks that may arise from human exposure to cyanotoxins is advisable.en
dc.publisherTaylor & Francis Inc, Philadelphia
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/176020/RS//
dc.relationCOST Action - ES1105
dc.rightsrestrictedAccess
dc.sourceJournal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology
dc.subjectcyanotoxinsen
dc.subjectepidemiologyen
dc.subjectprimary liver cancer (PLC)en
dc.subjectcirrhosisen
dc.subjectHepatistis C virus (HCV)en
dc.subjectHepatitis B virus (HBV)en
dc.subjectSerbiaen
dc.titleEpidemiology of Primary Liver Cancer in Serbia and Possible Connection With Cyanobacterial Bloomsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractБалтиц, Владимир; Дробац, Дамјана; Токоди, Нада; Видовић, Милка; Миладинов-Миков, Марица; Симеуновиц, Јелица; Свирцев, Зорица;
dc.citation.volume31
dc.citation.issue3
dc.citation.spage181
dc.citation.epage200
dc.citation.other31(3): 181-200
dc.citation.rankM22
dc.identifier.pmid24024518
dc.identifier.doi10.1080/10590501.2013.824187
dc.identifier.scopus2-s2.0-84884579527
dc.identifier.wos000324360000001
dc.type.versionpublishedVersion


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