We present a simple mathematical model of adsorbed mass fluctuations in microcantilever sensors operating in liquids, taking into account the effects of the transfer process of analyte molecules from a solution to the sensor surface. Using the derived expressions the analysis is performed in order to estimate the influence of mass transfer on the equilibrium fluctuations of the measured signal. The results show that mass transfer significantly influences the spectrum of fluctuations. The theory is useful for determination of limiting performances of cantilever sensors and for characterization of molecular binding-unbinding interactions using measured fluctuations in the sensor's signal.
Keywords:
Microcantilever sensor / Adsorption process / Adsorbed mass fluctuations / Liquid-phase detection
TY - JOUR
AU - Jokić, Ivana
AU - Đurić, Zoran G.
AU - Frantlović, Miloš
AU - Radulović, Katarina
AU - Krstajić, Predrag
PY - 2012
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/1132
AB - We present a simple mathematical model of adsorbed mass fluctuations in microcantilever sensors operating in liquids, taking into account the effects of the transfer process of analyte molecules from a solution to the sensor surface. Using the derived expressions the analysis is performed in order to estimate the influence of mass transfer on the equilibrium fluctuations of the measured signal. The results show that mass transfer significantly influences the spectrum of fluctuations. The theory is useful for determination of limiting performances of cantilever sensors and for characterization of molecular binding-unbinding interactions using measured fluctuations in the sensor's signal.
PB - Elsevier Science Bv, Amsterdam
T2 - Microelectronic Engineering
T1 - Fluctuations of the mass adsorbed on microcantilever sensor surface in liquid-phase chemical and biochemical detection
VL - 97
SP - 396
EP - 399
DO - 10.1016/j.mee.2012.03.038
ER -
@article{
author = "Jokić, Ivana and Đurić, Zoran G. and Frantlović, Miloš and Radulović, Katarina and Krstajić, Predrag",
year = "2012",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/1132",
abstract = "We present a simple mathematical model of adsorbed mass fluctuations in microcantilever sensors operating in liquids, taking into account the effects of the transfer process of analyte molecules from a solution to the sensor surface. Using the derived expressions the analysis is performed in order to estimate the influence of mass transfer on the equilibrium fluctuations of the measured signal. The results show that mass transfer significantly influences the spectrum of fluctuations. The theory is useful for determination of limiting performances of cantilever sensors and for characterization of molecular binding-unbinding interactions using measured fluctuations in the sensor's signal.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Microelectronic Engineering",
title = "Fluctuations of the mass adsorbed on microcantilever sensor surface in liquid-phase chemical and biochemical detection",
volume = "97",
pages = "396-399",
doi = "10.1016/j.mee.2012.03.038"
}
Jokić, I., Đurić, Z. G., Frantlović, M., Radulović, K.,& Krstajić, P. (2012). Fluctuations of the mass adsorbed on microcantilever sensor surface in liquid-phase chemical and biochemical detection.
Microelectronic Engineering
Elsevier Science Bv, Amsterdam., 97, 396-399.
https://doi.org/10.1016/j.mee.2012.03.038
Jokić I, Đurić ZG, Frantlović M, Radulović K, Krstajić P. Fluctuations of the mass adsorbed on microcantilever sensor surface in liquid-phase chemical and biochemical detection. Microelectronic Engineering. 2012;97:396-399
Jokić Ivana, Đurić Zoran G., Frantlović Miloš, Radulović Katarina, Krstajić Predrag, "Fluctuations of the mass adsorbed on microcantilever sensor surface in liquid-phase chemical and biochemical detection" Microelectronic Engineering, 97 (2012):396-399,
https://doi.org/10.1016/j.mee.2012.03.038 .
