Two sets of new peptides incorporating fulleropyrrolidine units Fp-GABAn-Glym-OtBu have been designed, synthesized and completely characterized. In the first series the chain contained only GABA (?-aminobutyric) residues, whereas in the second one glycine moieties were also inserted as well as GABA. Most of the target compounds were prepared by DCC/DMAP-assisted coupling of previously synthesized GABA-containing fulleropyrrolidinic acid and corresponding C-protected small peptides, although for two fulleropeptides [3+2] cycloadditions of azomethine ylides to C60 were employed. All new compounds were characterized by standard spectroscopic methods. Complete assignments of peptide spin systems were achieved by extensive NMR analysis (1H, 13C, H,H-COSY, HSQC, HMBC and TOCSY).
TY - JOUR
AU - Bjelaković, Mira
AU - Todorović, Nina
AU - Milić, Dragana
PY - 2012
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/1106
AB - Two sets of new peptides incorporating fulleropyrrolidine units Fp-GABAn-Glym-OtBu have been designed, synthesized and completely characterized. In the first series the chain contained only GABA (?-aminobutyric) residues, whereas in the second one glycine moieties were also inserted as well as GABA. Most of the target compounds were prepared by DCC/DMAP-assisted coupling of previously synthesized GABA-containing fulleropyrrolidinic acid and corresponding C-protected small peptides, although for two fulleropeptides [3+2] cycloadditions of azomethine ylides to C60 were employed. All new compounds were characterized by standard spectroscopic methods. Complete assignments of peptide spin systems were achieved by extensive NMR analysis (1H, 13C, H,H-COSY, HSQC, HMBC and TOCSY).
PB - Wiley-V C H Verlag Gmbh, Weinheim
T2 - European Journal of Organic Chemistry
T1 - An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides
IS - 27
SP - 5291
EP - 5300
DO - 10.1002/ejoc.201200274
ER -
@article{
author = "Bjelaković, Mira and Todorović, Nina and Milić, Dragana",
year = "2012",
abstract = "Two sets of new peptides incorporating fulleropyrrolidine units Fp-GABAn-Glym-OtBu have been designed, synthesized and completely characterized. In the first series the chain contained only GABA (?-aminobutyric) residues, whereas in the second one glycine moieties were also inserted as well as GABA. Most of the target compounds were prepared by DCC/DMAP-assisted coupling of previously synthesized GABA-containing fulleropyrrolidinic acid and corresponding C-protected small peptides, although for two fulleropeptides [3+2] cycloadditions of azomethine ylides to C60 were employed. All new compounds were characterized by standard spectroscopic methods. Complete assignments of peptide spin systems were achieved by extensive NMR analysis (1H, 13C, H,H-COSY, HSQC, HMBC and TOCSY).",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "European Journal of Organic Chemistry",
title = "An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides",
number = "27",
pages = "5291-5300",
doi = "10.1002/ejoc.201200274"
}
Bjelaković, M., Todorović, N.,& Milić, D.. (2012). An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides. in European Journal of Organic Chemistry
Wiley-V C H Verlag Gmbh, Weinheim.(27), 5291-5300.
https://doi.org/10.1002/ejoc.201200274
Bjelaković M, Todorović N, Milić D. An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides. in European Journal of Organic Chemistry. 2012;(27):5291-5300.
doi:10.1002/ejoc.201200274 .
Bjelaković, Mira, Todorović, Nina, Milić, Dragana, "An Approach to Nanobioparticles - Synthesis and Characterization of Fulleropeptides" in European Journal of Organic Chemistry, no. 27 (2012):5291-5300,
https://doi.org/10.1002/ejoc.201200274 . .
