Four new cationic Co(II) complexes with N,N',N '',N'''-tetrakis (2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and dianion of one the aliphatic dicarboxylic acids: butanedioic acid (succinic) acid = succH(2), pentanedioic (glutaric) acid = gluH(2), hexanedioic acid (adipic) acid = adipH(2) or decanedioic acid (sebacic) acid = sebH(2) of general formula [Co-2(L)(tpmc)](ClO4)(2)center dot xY, L2- = succ, x = 1, Y = H2O; L = glu, x = 1, Y = H2O; L = adip, x = 1.5, Y = H2O; L = seb, x = 1, Y = CH3CN were isolated. The composition and charge are proposed based on elemental analyses (C, H. N) and electrical conductivity measurements. UV-Vis and FTIR spectral data and magnetic moments were in accordance with high-spin Co(II) state. It is proposed that in all complexes Co(II) is hexa-coordinated out of cyclam ring and that both carboxylic groups from dicarboxylate bridge participate in coordination. Oxygens from one group are most likely bonded to the same Co(II) ion thus forming a... four-membered ring. The in vitro antibacterial/antiproliferative activities of the complexes were in some cases enhanced compared with the simple Co(II) salt and free ligands, tested as controls.
TY - JOUR
AU - Tanasković, Slađana B.
AU - Vuckovic, G.
AU - Antonijevic-Nikolic, M.
AU - Stanojković, Tatjana
AU - Gojgić-Cvijović, Gordana
PY - 2012
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/1093
AB - Four new cationic Co(II) complexes with N,N',N '',N'''-tetrakis (2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and dianion of one the aliphatic dicarboxylic acids: butanedioic acid (succinic) acid = succH(2), pentanedioic (glutaric) acid = gluH(2), hexanedioic acid (adipic) acid = adipH(2) or decanedioic acid (sebacic) acid = sebH(2) of general formula [Co-2(L)(tpmc)](ClO4)(2)center dot xY, L2- = succ, x = 1, Y = H2O; L = glu, x = 1, Y = H2O; L = adip, x = 1.5, Y = H2O; L = seb, x = 1, Y = CH3CN were isolated. The composition and charge are proposed based on elemental analyses (C, H. N) and electrical conductivity measurements. UV-Vis and FTIR spectral data and magnetic moments were in accordance with high-spin Co(II) state. It is proposed that in all complexes Co(II) is hexa-coordinated out of cyclam ring and that both carboxylic groups from dicarboxylate bridge participate in coordination. Oxygens from one group are most likely bonded to the same Co(II) ion thus forming a four-membered ring. The in vitro antibacterial/antiproliferative activities of the complexes were in some cases enhanced compared with the simple Co(II) salt and free ligands, tested as controls.
PB - Elsevier
T2 - Journal of Molecular Structure
T1 - Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates
VL - 1029
SP - 1
EP - 7
DO - 10.1016/j.molstruc.2012.06.055
ER -
@article{
author = "Tanasković, Slađana B. and Vuckovic, G. and Antonijevic-Nikolic, M. and Stanojković, Tatjana and Gojgić-Cvijović, Gordana",
year = "2012",
abstract = "Four new cationic Co(II) complexes with N,N',N '',N'''-tetrakis (2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and dianion of one the aliphatic dicarboxylic acids: butanedioic acid (succinic) acid = succH(2), pentanedioic (glutaric) acid = gluH(2), hexanedioic acid (adipic) acid = adipH(2) or decanedioic acid (sebacic) acid = sebH(2) of general formula [Co-2(L)(tpmc)](ClO4)(2)center dot xY, L2- = succ, x = 1, Y = H2O; L = glu, x = 1, Y = H2O; L = adip, x = 1.5, Y = H2O; L = seb, x = 1, Y = CH3CN were isolated. The composition and charge are proposed based on elemental analyses (C, H. N) and electrical conductivity measurements. UV-Vis and FTIR spectral data and magnetic moments were in accordance with high-spin Co(II) state. It is proposed that in all complexes Co(II) is hexa-coordinated out of cyclam ring and that both carboxylic groups from dicarboxylate bridge participate in coordination. Oxygens from one group are most likely bonded to the same Co(II) ion thus forming a four-membered ring. The in vitro antibacterial/antiproliferative activities of the complexes were in some cases enhanced compared with the simple Co(II) salt and free ligands, tested as controls.",
publisher = "Elsevier",
journal = "Journal of Molecular Structure",
title = "Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates",
volume = "1029",
pages = "1-7",
doi = "10.1016/j.molstruc.2012.06.055"
}
Tanasković, S. B., Vuckovic, G., Antonijevic-Nikolic, M., Stanojković, T.,& Gojgić-Cvijović, G.. (2012). Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates. in Journal of Molecular Structure
Elsevier., 1029, 1-7.
https://doi.org/10.1016/j.molstruc.2012.06.055
Tanasković SB, Vuckovic G, Antonijevic-Nikolic M, Stanojković T, Gojgić-Cvijović G. Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates. in Journal of Molecular Structure. 2012;1029:1-7.
doi:10.1016/j.molstruc.2012.06.055 .
Tanasković, Slađana B., Vuckovic, G., Antonijevic-Nikolic, M., Stanojković, Tatjana, Gojgić-Cvijović, Gordana, "Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates" in Journal of Molecular Structure, 1029 (2012):1-7,
https://doi.org/10.1016/j.molstruc.2012.06.055 . .
