The adsorption-desorption (AD) noise in nanowire FET biosensors is analyzed, which manifests itself in the form of gate voltage fluctuations resulting from the fluctuations of the number of adsorbed particles. The derived theoretical model of the fluctuations takes into account the mass transfer effects. The numerical calculations show that when the mass transfer is slow, the low-frequency amplitude and the corner frequency of the Lorentzian AD noise spectrum obtained by derived expressions are significantly different compared to the same parameters predicted by the model that neglects mass transport effects. The presented analysis enables good estimation of these parameters from the measured noise spectrum, which is important because they are used as the source of information about the analyte concentration and the kinetics of biomolecular interactions.
Source:
28th International Conference on Microelectronics - Proceedings, MIEL 2012, 2012, 203-206
Publisher:
Institute of Electrical and Electronics Engineers Inc.
TY - CONF
AU - Radulović, Katarina
AU - Jokić, Ivana
AU - Frantlović, Miloš
AU - Đurić, Zoran G.
PY - 2012
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/1058
AB - The adsorption-desorption (AD) noise in nanowire FET biosensors is analyzed, which manifests itself in the form of gate voltage fluctuations resulting from the fluctuations of the number of adsorbed particles. The derived theoretical model of the fluctuations takes into account the mass transfer effects. The numerical calculations show that when the mass transfer is slow, the low-frequency amplitude and the corner frequency of the Lorentzian AD noise spectrum obtained by derived expressions are significantly different compared to the same parameters predicted by the model that neglects mass transport effects. The presented analysis enables good estimation of these parameters from the measured noise spectrum, which is important because they are used as the source of information about the analyte concentration and the kinetics of biomolecular interactions.
PB - Institute of Electrical and Electronics Engineers Inc.
C3 - 28th International Conference on Microelectronics - Proceedings, MIEL 2012
T1 - Adsorption-Desorption Noise in Nanowire FET Biosensors
SP - 203
EP - 206
DO - 10.1109/MIEL.2012.6222834
ER -
@conference{
author = "Radulović, Katarina and Jokić, Ivana and Frantlović, Miloš and Đurić, Zoran G.",
year = "2012",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/1058",
abstract = "The adsorption-desorption (AD) noise in nanowire FET biosensors is analyzed, which manifests itself in the form of gate voltage fluctuations resulting from the fluctuations of the number of adsorbed particles. The derived theoretical model of the fluctuations takes into account the mass transfer effects. The numerical calculations show that when the mass transfer is slow, the low-frequency amplitude and the corner frequency of the Lorentzian AD noise spectrum obtained by derived expressions are significantly different compared to the same parameters predicted by the model that neglects mass transport effects. The presented analysis enables good estimation of these parameters from the measured noise spectrum, which is important because they are used as the source of information about the analyte concentration and the kinetics of biomolecular interactions.",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
journal = "28th International Conference on Microelectronics - Proceedings, MIEL 2012",
title = "Adsorption-Desorption Noise in Nanowire FET Biosensors",
pages = "203-206",
doi = "10.1109/MIEL.2012.6222834"
}
Radulović, K., Jokić, I., Frantlović, M.,& Đurić, Z. G. (2012). Adsorption-Desorption Noise in Nanowire FET Biosensors.
28th International Conference on Microelectronics - Proceedings, MIEL 2012
Institute of Electrical and Electronics Engineers Inc.., 203-206.
https://doi.org/10.1109/MIEL.2012.6222834
Radulović K, Jokić I, Frantlović M, Đurić ZG. Adsorption-Desorption Noise in Nanowire FET Biosensors. 28th International Conference on Microelectronics - Proceedings, MIEL 2012. 2012;:203-206
Radulović Katarina, Jokić Ivana, Frantlović Miloš, Đurić Zoran G., "Adsorption-Desorption Noise in Nanowire FET Biosensors" 28th International Conference on Microelectronics - Proceedings, MIEL 2012 (2012):203-206,
https://doi.org/10.1109/MIEL.2012.6222834 .
