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Synthesis and antitumour activity of two dephenilated (-)-goniofufurone analogues
(Valahia University of TargovisteUniversity Politehnica of Bucharest, 2019)
(-)-Goniofufurone (1) is a synthetic styryl lactone that exhibits significant antitumor activity. In the search for new and more potent antitumor agents the synthesis of lactones 5 and 6 was planned from D-glucose. Compounds ...
Synthesis and antiprol iferative activity of (+)-muricatacin and two novel conformationally constrained analogues
(IUPAC, 2010)
Herein we describe a modified total synthesis of (+)-Muricatacin starting from D-xylose, as well as synthesis of two new conformationally constrained (+)-muricatacin mimics from D-glucose.
Synthesis and biological activity of new thiazole isosteres of goniofufurone and 7-epi-goniofufurone
(IUPAC, 2010)
Herein we report a total synthesis of two novel (7-epi-)goniofufurone isosteres bearing a 2-thiazolyl-4-carboxylic acid ethyl ester moiety instead of the aromatic ring at C-7.