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Electrostatic surface potential calculation on several new halogenated benzimidazole-like dopaminergic ligands
(Wiley-VCH Verlag, 2004)
We examined the effects of the electron density distribution (electrostatic surface potential; ESP) of several new benzimidazole-type ligands on their binding affinity for the D 1 and D 2 dopamine receptors (DAR). Receptors ...
Modeling of the D2 dopamine receptor arylpiperazine binding site for 1-{2-[5-(1H-benzimidazole-2-thione)]ethyl}-4-arylpiperazines
(Wiley-VCH Verlag, 2004)
Docking of several 1-{2-[5-(1H-benzimidazole-2-thione)]ethyl}-4- and 1-benzylarylpiperazines to the D 2 dopamine receptor (DAR) was examined. The binding pocket of the D 2 DAR defined according to Teeter and DuRand [1] was ...