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Synthesis of several substituted phenylpiperazines behaving as mixed D2/5HT(1A) ligands
(Blackwell Publishing Ltd, 1997)
Twenty-two different compounds have been synthesized with the aim of creating new, mixed D2/5HT(1A) ligands. For this purpose l-substituted phenylpiperazines attached by the N-4 nitrogen to dopaminergic pharmacophores of ...
Synthesis and dopaminergic features of six novel 3-arylpiperidines
(Bollettino Chimico Farmaceutico, 1998)
Four substituted 3-aryl-1-{2-[5-(1H-benzimidazole)]ethyl}piperidines and two 3-aryl-1-{2-[6-(1,4-dihydroxyquinoxaline-2,3-dione)]ethyl} piperidines were synthesized, characterized and evaluated for in vitro binding affinity ...