TY  - JOUR
AU  - Vujić, Bojan
AU  - Vidaković, Vera
AU  - Jadranin, Milka
AU  - Novaković, Irena
AU  - Trifunović, Snežana
AU  - Tešević, Vele
AU  - Mandić, Boris
PY  - 2020
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/3962
UR  - http://ibiss-r.rcub.bg.ac.rs/handle/123456789/3620
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3581
AB  - Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.
PB  - MDPI
T2  - Plants
T1  - Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts
VL  - 9
IS  - 3
SP  - 337
DO  - 10.3390/plants9030337
ER  - 

@article{
author = "Vujić, Bojan and Vidaković, Vera and Jadranin, Milka and Novaković, Irena and Trifunović, Snežana and Tešević, Vele and Mandić, Boris",
year = "2020",
abstract = "Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.",
publisher = "MDPI",
journal = "Plants",
title = "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts",
volume = "9",
number = "3",
pages = "337",
doi = "10.3390/plants9030337"
}

Vujić, B., Vidaković, V., Jadranin, M., Novaković, I., Trifunović, S., Tešević, V.,& Mandić, B.. (2020). Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants
MDPI., 9(3), 337.
https://doi.org/10.3390/plants9030337

Vujić B, Vidaković V, Jadranin M, Novaković I, Trifunović S, Tešević V, Mandić B. Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants. 2020;9(3):337.
doi:10.3390/plants9030337 .

Vujić, Bojan, Vidaković, Vera, Jadranin, Milka, Novaković, Irena, Trifunović, Snežana, Tešević, Vele, Mandić, Boris, "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts" in Plants, 9, no. 3 (2020):337,
https://doi.org/10.3390/plants9030337 . .

TY  - JOUR
AU  - Vidaković, Vera
AU  - Novaković, Miroslav
AU  - Popovic, Zorica
AU  - Janković, Milan
AU  - Matić, Rada
AU  - Tešević, Vele
AU  - Bojovic, Srdjan
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2459
AB  - Diarylheptanoids are a group of secondary metabolites widely distributed in the Betulaceae family and characteristic for Alnus species. In this study, the chemotaxonomic power of diarylheptanoids, such as hirsutanonol-5-O-beta-d-glucopyranoside, rubranoside A, oregonin, platyphylloside, alnuside A and hirsutanonol, has been investigated in combination with principal component analysis (PCA) for differentiation of Alnus species. Concentrations of six diarylheptanoids in the bark extracts of two natural populations of Alnus glutinosa (black alder) and Alnus incana (gray alder) were determined by -ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). PCA clearly shows the separation of three groups. Populations I (A. glutinosa) and II (A. incana) both consisted of individuals of the corresponding species. Four individuals from both sampled populations formed a separate group (population III), which possibly represents a hybrid group. Accordingly, diarylheptanoids may serve in combination with PCA as chemotaxonomic markers at the species level, which may also reveal hybrid species.
PB  - Walter De Gruyter
T2  - Holzforschung
T1  - Significance of diarylheptanoids for chemotaxonomical distinguishing between Alnus glutinosa and Alnus incana
VL  - 72
IS  - 1
SP  - 9
EP  - 16
DO  - 10.1515/hf-2017-0074
ER  - 

@article{
author = "Vidaković, Vera and Novaković, Miroslav and Popovic, Zorica and Janković, Milan and Matić, Rada and Tešević, Vele and Bojovic, Srdjan",
year = "2018",
abstract = "Diarylheptanoids are a group of secondary metabolites widely distributed in the Betulaceae family and characteristic for Alnus species. In this study, the chemotaxonomic power of diarylheptanoids, such as hirsutanonol-5-O-beta-d-glucopyranoside, rubranoside A, oregonin, platyphylloside, alnuside A and hirsutanonol, has been investigated in combination with principal component analysis (PCA) for differentiation of Alnus species. Concentrations of six diarylheptanoids in the bark extracts of two natural populations of Alnus glutinosa (black alder) and Alnus incana (gray alder) were determined by -ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). PCA clearly shows the separation of three groups. Populations I (A. glutinosa) and II (A. incana) both consisted of individuals of the corresponding species. Four individuals from both sampled populations formed a separate group (population III), which possibly represents a hybrid group. Accordingly, diarylheptanoids may serve in combination with PCA as chemotaxonomic markers at the species level, which may also reveal hybrid species.",
publisher = "Walter De Gruyter",
journal = "Holzforschung",
title = "Significance of diarylheptanoids for chemotaxonomical distinguishing between Alnus glutinosa and Alnus incana",
volume = "72",
number = "1",
pages = "9-16",
doi = "10.1515/hf-2017-0074"
}

Vidaković, V., Novaković, M., Popovic, Z., Janković, M., Matić, R., Tešević, V.,& Bojovic, S.. (2018). Significance of diarylheptanoids for chemotaxonomical distinguishing between Alnus glutinosa and Alnus incana. in Holzforschung
Walter De Gruyter., 72(1), 9-16.
https://doi.org/10.1515/hf-2017-0074

Vidaković V, Novaković M, Popovic Z, Janković M, Matić R, Tešević V, Bojovic S. Significance of diarylheptanoids for chemotaxonomical distinguishing between Alnus glutinosa and Alnus incana. in Holzforschung. 2018;72(1):9-16.
doi:10.1515/hf-2017-0074 .

Vidaković, Vera, Novaković, Miroslav, Popovic, Zorica, Janković, Milan, Matić, Rada, Tešević, Vele, Bojovic, Srdjan, "Significance of diarylheptanoids for chemotaxonomical distinguishing between Alnus glutinosa and Alnus incana" in Holzforschung, 72, no. 1 (2018):9-16,
https://doi.org/10.1515/hf-2017-0074 . .

TY  - JOUR
AU  - Vidaković, Vera
AU  - Stefanovic, Milena
AU  - Novaković, Miroslav
AU  - Jadranin, Milka
AU  - Popovic, Zorica
AU  - Matić, Rada
AU  - Tešević, Vele
AU  - Bojovic, Srdjan
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2377
AB  - The reliability of diarylheptanoids as chemotaxonomic markers at inter-and intraspecific levels has been investigated. Six diarylheptanoids were quantified in bark ethanol extracts of four Alnus spp. populations by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The populations described here as locus classicus Alnus glutinosa (I) and locus classicus Alnus incana (III) are clearly differentiated. Compared to population I, individuals in population III have higher extract yields and hirsutanonol-5-O-beta-D-glucopyranoside content and lower contents of hirsutanonol, rubranoside A and oregonin. Individuals from neighboring populations of A. glutinosa (II) and A. incana (IV) share similar contents of hirsutanonol. All the studied populations exhibit a high intrapopulation variability of the selected diarylheptanoids; they have a heterogeneous chemotype and they partially overlap. The geographical proximity of populations II and IV increases their chemical similarity. Principal component analysis (PCA) clearly shows that the biggest dispersion of individuals lies within population IV. The reason for its heterogeneity might be its physical proximity to population II, i. e. the appearance of hybrids. Also, geometric morphometrics of leaves was performed as a screening criterion for spontaneous hybrids.
PB  - Walter De Gruyter
T2  - Holzforschung
T1  - Inter- and intraspecific variability of selected diarylheptanoid compounds and leaf morphometric traits in Alnus glutinosa and Alnus incana
VL  - 72
IS  - 12
SP  - 1031
EP  - 1041
DO  - 10.1515/hf-2018-0019
ER  - 

@article{
author = "Vidaković, Vera and Stefanovic, Milena and Novaković, Miroslav and Jadranin, Milka and Popovic, Zorica and Matić, Rada and Tešević, Vele and Bojovic, Srdjan",
year = "2018",
abstract = "The reliability of diarylheptanoids as chemotaxonomic markers at inter-and intraspecific levels has been investigated. Six diarylheptanoids were quantified in bark ethanol extracts of four Alnus spp. populations by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The populations described here as locus classicus Alnus glutinosa (I) and locus classicus Alnus incana (III) are clearly differentiated. Compared to population I, individuals in population III have higher extract yields and hirsutanonol-5-O-beta-D-glucopyranoside content and lower contents of hirsutanonol, rubranoside A and oregonin. Individuals from neighboring populations of A. glutinosa (II) and A. incana (IV) share similar contents of hirsutanonol. All the studied populations exhibit a high intrapopulation variability of the selected diarylheptanoids; they have a heterogeneous chemotype and they partially overlap. The geographical proximity of populations II and IV increases their chemical similarity. Principal component analysis (PCA) clearly shows that the biggest dispersion of individuals lies within population IV. The reason for its heterogeneity might be its physical proximity to population II, i. e. the appearance of hybrids. Also, geometric morphometrics of leaves was performed as a screening criterion for spontaneous hybrids.",
publisher = "Walter De Gruyter",
journal = "Holzforschung",
title = "Inter- and intraspecific variability of selected diarylheptanoid compounds and leaf morphometric traits in Alnus glutinosa and Alnus incana",
volume = "72",
number = "12",
pages = "1031-1041",
doi = "10.1515/hf-2018-0019"
}

Vidaković, V., Stefanovic, M., Novaković, M., Jadranin, M., Popovic, Z., Matić, R., Tešević, V.,& Bojovic, S.. (2018). Inter- and intraspecific variability of selected diarylheptanoid compounds and leaf morphometric traits in Alnus glutinosa and Alnus incana. in Holzforschung
Walter De Gruyter., 72(12), 1031-1041.
https://doi.org/10.1515/hf-2018-0019

Vidaković V, Stefanovic M, Novaković M, Jadranin M, Popovic Z, Matić R, Tešević V, Bojovic S. Inter- and intraspecific variability of selected diarylheptanoid compounds and leaf morphometric traits in Alnus glutinosa and Alnus incana. in Holzforschung. 2018;72(12):1031-1041.
doi:10.1515/hf-2018-0019 .

Vidaković, Vera, Stefanovic, Milena, Novaković, Miroslav, Jadranin, Milka, Popovic, Zorica, Matić, Rada, Tešević, Vele, Bojovic, Srdjan, "Inter- and intraspecific variability of selected diarylheptanoid compounds and leaf morphometric traits in Alnus glutinosa and Alnus incana" in Holzforschung, 72, no. 12 (2018):1031-1041,
https://doi.org/10.1515/hf-2018-0019 . .

TY  - JOUR
AU  - Đorđević, Tamara
AU  - Kašanin-Grubin, Milica
AU  - Gajica, Gordana
AU  - Popovic, Zorica
AU  - Matić, Rada
AU  - Josić, Ljuba
AU  - Milenković, Milan
AU  - Lazarević, Aleksandar
AU  - Jovančićević, Branimir
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2019
AB  - On a global scale, it was found that the surface of the vulnerable land and land affected by degradation has been increasing in the last decades and that unsustainable land management is one of the key drivers of land degradation. In order to assess the effect that these changes have on biodiversity and ecosystem services, and to realize appropriate planning and management actions for the conservation of the environment, it is essential to identify and quantify changes caused by land degradation. The aim of this study was to determine the impact of the geological setting, i.e., the type of bedrock, and land use on the physicochemical properties of soil in the vulnerable mountainous areas of Fruska Gora. For the purpose of this study, 30 soil samples were collected from a depth of 0-20 cm at four locations on the Fruska Gora Mt. The geological setting was serpentinite and marl and land cover was forest and meadow. The following soil properties were determined: pH, redox potential (Eh), electrical conductivity (EC), total dissolved solids (TDS), concentrations of available cations Ca, Mg, K, Na, contents of organic carbon (Corg) and nitrogen (N). The correlation between the obtained parameters was tested with two-way ANOVA and principal component analyses (PCA). All of the obtained results indicated that the soil physicochemical properties depended on the geological setting and that rock composition has to be taken into consideration during land management.
PB  - Serbian Chemical Soc, Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - Fruska Gora mountainous environments - assessing the impact of geological setting and land use on soil properties
VL  - 81
IS  - 4
SP  - 459
EP  - 468
DO  - 10.2298/JSC151014001D
ER  - 

@article{
author = "Đorđević, Tamara and Kašanin-Grubin, Milica and Gajica, Gordana and Popovic, Zorica and Matić, Rada and Josić, Ljuba and Milenković, Milan and Lazarević, Aleksandar and Jovančićević, Branimir",
year = "2016",
abstract = "On a global scale, it was found that the surface of the vulnerable land and land affected by degradation has been increasing in the last decades and that unsustainable land management is one of the key drivers of land degradation. In order to assess the effect that these changes have on biodiversity and ecosystem services, and to realize appropriate planning and management actions for the conservation of the environment, it is essential to identify and quantify changes caused by land degradation. The aim of this study was to determine the impact of the geological setting, i.e., the type of bedrock, and land use on the physicochemical properties of soil in the vulnerable mountainous areas of Fruska Gora. For the purpose of this study, 30 soil samples were collected from a depth of 0-20 cm at four locations on the Fruska Gora Mt. The geological setting was serpentinite and marl and land cover was forest and meadow. The following soil properties were determined: pH, redox potential (Eh), electrical conductivity (EC), total dissolved solids (TDS), concentrations of available cations Ca, Mg, K, Na, contents of organic carbon (Corg) and nitrogen (N). The correlation between the obtained parameters was tested with two-way ANOVA and principal component analyses (PCA). All of the obtained results indicated that the soil physicochemical properties depended on the geological setting and that rock composition has to be taken into consideration during land management.",
publisher = "Serbian Chemical Soc, Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "Fruska Gora mountainous environments - assessing the impact of geological setting and land use on soil properties",
volume = "81",
number = "4",
pages = "459-468",
doi = "10.2298/JSC151014001D"
}

Đorđević, T., Kašanin-Grubin, M., Gajica, G., Popovic, Z., Matić, R., Josić, L., Milenković, M., Lazarević, A.,& Jovančićević, B.. (2016). Fruska Gora mountainous environments - assessing the impact of geological setting and land use on soil properties. in Journal of the Serbian Chemical Society
Serbian Chemical Soc, Belgrade., 81(4), 459-468.
https://doi.org/10.2298/JSC151014001D

Đorđević T, Kašanin-Grubin M, Gajica G, Popovic Z, Matić R, Josić L, Milenković M, Lazarević A, Jovančićević B. Fruska Gora mountainous environments - assessing the impact of geological setting and land use on soil properties. in Journal of the Serbian Chemical Society. 2016;81(4):459-468.
doi:10.2298/JSC151014001D .

Đorđević, Tamara, Kašanin-Grubin, Milica, Gajica, Gordana, Popovic, Zorica, Matić, Rada, Josić, Ljuba, Milenković, Milan, Lazarević, Aleksandar, Jovančićević, Branimir, "Fruska Gora mountainous environments - assessing the impact of geological setting and land use on soil properties" in Journal of the Serbian Chemical Society, 81, no. 4 (2016):459-468,
https://doi.org/10.2298/JSC151014001D . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Tešević, Vele
AU  - Đorđević, Iris
AU  - Todosijević, Marina
AU  - Jadranin, Milka
AU  - Bojovic, Srdjan
AU  - Marin, Petar D.
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1006
AB  - This is the first report of individual variability and population diversity of the contents of nonacosan-10-ol and n-alkanes in the needle cuticular waxes of Bosnian pines originated from Montenegro, regarded as Pinus heldreichii var. leucodermis, and from Serbia, regarded as P. heldreichii var. pancici. The amount of nonacosan-10-ol varied individually from 27.4 to 73.2% (55.5% in average), but differences between the four investigated populations were not statistically confirmed. The size of the n-alkanes ranged from C18 to C33. The most abundant n-alkanes were C23, C27, and C25 (12.2, 11.2, and 10.8% in average, resp.). The carbon preference index (CPI) of the n-alkanes ranged from 0.8 to 3.1 (1.6 in average), while the average chain length (ACL) ranged from 20.9 to 26.5 (24.4 in average). Long-chain and mid-chain n-alkanes prevailed (49.6 and 37.9% in average, resp.). It was also found that the populations of P. heldreichii var. leucodermis had predominantly a narrower range of n-alkanes (C18?C31) than the trees of the variety pancici (C18?C33). Differences between the varieties were also significant for most of the other characteristics of the n-alkane pattern (e.g., most abundant n-alkanes, CPI, ACL, and relative proportion of short-, mid-, and long-chain n-alkanes). The principle component and cluster analyses of eleven n-alkanes confirmed the significant diversity of these two varieties.
PB  - Wiley-Blackwell, Malden
T2  - Chemistry & Biodiversity
T1  - Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii
VL  - 9
IS  - 1
SP  - 80
EP  - 90
DO  - 10.1002/cbdv.201100179
ER  - 

@article{
author = "Nikolić, Biljana and Tešević, Vele and Đorđević, Iris and Todosijević, Marina and Jadranin, Milka and Bojovic, Srdjan and Marin, Petar D.",
year = "2012",
abstract = "This is the first report of individual variability and population diversity of the contents of nonacosan-10-ol and n-alkanes in the needle cuticular waxes of Bosnian pines originated from Montenegro, regarded as Pinus heldreichii var. leucodermis, and from Serbia, regarded as P. heldreichii var. pancici. The amount of nonacosan-10-ol varied individually from 27.4 to 73.2% (55.5% in average), but differences between the four investigated populations were not statistically confirmed. The size of the n-alkanes ranged from C18 to C33. The most abundant n-alkanes were C23, C27, and C25 (12.2, 11.2, and 10.8% in average, resp.). The carbon preference index (CPI) of the n-alkanes ranged from 0.8 to 3.1 (1.6 in average), while the average chain length (ACL) ranged from 20.9 to 26.5 (24.4 in average). Long-chain and mid-chain n-alkanes prevailed (49.6 and 37.9% in average, resp.). It was also found that the populations of P. heldreichii var. leucodermis had predominantly a narrower range of n-alkanes (C18?C31) than the trees of the variety pancici (C18?C33). Differences between the varieties were also significant for most of the other characteristics of the n-alkane pattern (e.g., most abundant n-alkanes, CPI, ACL, and relative proportion of short-, mid-, and long-chain n-alkanes). The principle component and cluster analyses of eleven n-alkanes confirmed the significant diversity of these two varieties.",
publisher = "Wiley-Blackwell, Malden",
journal = "Chemistry & Biodiversity",
title = "Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii",
volume = "9",
number = "1",
pages = "80-90",
doi = "10.1002/cbdv.201100179"
}

Nikolić, B., Tešević, V., Đorđević, I., Todosijević, M., Jadranin, M., Bojovic, S.,& Marin, P. D.. (2012). Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii. in Chemistry & Biodiversity
Wiley-Blackwell, Malden., 9(1), 80-90.
https://doi.org/10.1002/cbdv.201100179

Nikolić B, Tešević V, Đorđević I, Todosijević M, Jadranin M, Bojovic S, Marin PD. Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii. in Chemistry & Biodiversity. 2012;9(1):80-90.
doi:10.1002/cbdv.201100179 .

Nikolić, Biljana, Tešević, Vele, Đorđević, Iris, Todosijević, Marina, Jadranin, Milka, Bojovic, Srdjan, Marin, Petar D., "Chemodiversity of Nonacosan-10-ol and n-Alkanes in the Needle Wax of Pinus heldreichii" in Chemistry & Biodiversity, 9, no. 1 (2012):80-90,
https://doi.org/10.1002/cbdv.201100179 . .