TY  - JOUR
AU  - Svirčev, Zorica
AU  - Drobac, Damjana
AU  - Tokodi, Nada
AU  - Vidović, Milka
AU  - Simeunovic, Jelica
AU  - Miladinov-Mikov, Marica
AU  - Baltic, Vladimir
PY  - 2013
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1197
AB  - Today, the occurrence of harmful cyanobacterial blooms is a common phenomenon and a potential global health problem. Cyanobacteria can produce metabolites highly toxic to humans. More than 80% of reservoirs used for water supply in Central Serbia have bloomed over the past 80years. A 10-year epidemiological study showed a significant increase in the incidence of primary liver cancer (PLC) in the regions where water from the blooming reservoirs was used for human consumption. At the same time, no correlation was found between the incidence of PLC and other risk factors, such as cirrhosis and hepatitis viruses. Given the strong association with PLC induction and various known possible mechanisms of carcinogenic action, it is highly possible that, cyanotoxinsacting as initiator and promotermay be the major risk factor that acts synergistically with other risk factors to cause increased incidence of PLC. However, at present, it is still not certain whether cyanotoxins alone were sufficient to induce PLC. Therefore, additional assessment of the health risks that may arise from human exposure to cyanotoxins is advisable.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology
T1  - Epidemiology of Primary Liver Cancer in Serbia and Possible Connection With Cyanobacterial Blooms
VL  - 31
IS  - 3
SP  - 181
EP  - 200
DO  - 10.1080/10590501.2013.824187
ER  - 

@article{
author = "Svirčev, Zorica and Drobac, Damjana and Tokodi, Nada and Vidović, Milka and Simeunovic, Jelica and Miladinov-Mikov, Marica and Baltic, Vladimir",
year = "2013",
abstract = "Today, the occurrence of harmful cyanobacterial blooms is a common phenomenon and a potential global health problem. Cyanobacteria can produce metabolites highly toxic to humans. More than 80% of reservoirs used for water supply in Central Serbia have bloomed over the past 80years. A 10-year epidemiological study showed a significant increase in the incidence of primary liver cancer (PLC) in the regions where water from the blooming reservoirs was used for human consumption. At the same time, no correlation was found between the incidence of PLC and other risk factors, such as cirrhosis and hepatitis viruses. Given the strong association with PLC induction and various known possible mechanisms of carcinogenic action, it is highly possible that, cyanotoxinsacting as initiator and promotermay be the major risk factor that acts synergistically with other risk factors to cause increased incidence of PLC. However, at present, it is still not certain whether cyanotoxins alone were sufficient to induce PLC. Therefore, additional assessment of the health risks that may arise from human exposure to cyanotoxins is advisable.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology",
title = "Epidemiology of Primary Liver Cancer in Serbia and Possible Connection With Cyanobacterial Blooms",
volume = "31",
number = "3",
pages = "181-200",
doi = "10.1080/10590501.2013.824187"
}

Svirčev, Z., Drobac, D., Tokodi, N., Vidović, M., Simeunovic, J., Miladinov-Mikov, M.,& Baltic, V.. (2013). Epidemiology of Primary Liver Cancer in Serbia and Possible Connection With Cyanobacterial Blooms. in Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology
Taylor & Francis Inc, Philadelphia., 31(3), 181-200.
https://doi.org/10.1080/10590501.2013.824187

Svirčev Z, Drobac D, Tokodi N, Vidović M, Simeunovic J, Miladinov-Mikov M, Baltic V. Epidemiology of Primary Liver Cancer in Serbia and Possible Connection With Cyanobacterial Blooms. in Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology. 2013;31(3):181-200.
doi:10.1080/10590501.2013.824187 .

Svirčev, Zorica, Drobac, Damjana, Tokodi, Nada, Vidović, Milka, Simeunovic, Jelica, Miladinov-Mikov, Marica, Baltic, Vladimir, "Epidemiology of Primary Liver Cancer in Serbia and Possible Connection With Cyanobacterial Blooms" in Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology, 31, no. 3 (2013):181-200,
https://doi.org/10.1080/10590501.2013.824187 . .