TY  - CONF
AU  - Stanić, Dragana
AU  - Nikolić, Milan
AU  - Stojanović, Srđan
AU  - Raičević, Smiljana
AU  - Niketić, Vesna
PY  - 2003
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6535
AB  - Our results demonstrate that MnSOD (E. coli)-stimulated generation of NO+ and NO- species is associated with nitration of enzyme tyrosine residues and dityrosinc formation, which cause enzyme inactivation. This represents to our knowledge entirely knew mode of NO-mediated tyrosine nitration. Peroxynitritc treatment of MnSOD (E. coli) caused nitration of tyrosine residues and loss of activity, but not dityrosinc formation. Considering high structural similarities of active centers of these two enzymes, observed differences arc surprising. Wc assume that different reactivity of MnSOD (E. coli) toward NO and ONOO- comparing to that of hMnSOD may be (partly) explained by higher flexibility of its (dimeric) structure comparing to that of hMnSOD, which is tetramer.
PB  - Turkish Biochemical Society
C3  - Turkish Journal of Biochemistry
T1  - The effects of nitric oxide (NO) and peroxynitrite on MnSOD (E.coli)
VL  - 28
IS  - 3
SP  - 116
EP  - 117
UR  - https://hdl.handle.net/21.15107/rcub_cer_6535
ER  - 

@conference{
author = "Stanić, Dragana and Nikolić, Milan and Stojanović, Srđan and Raičević, Smiljana and Niketić, Vesna",
year = "2003",
abstract = "Our results demonstrate that MnSOD (E. coli)-stimulated generation of NO+ and NO- species is associated with nitration of enzyme tyrosine residues and dityrosinc formation, which cause enzyme inactivation. This represents to our knowledge entirely knew mode of NO-mediated tyrosine nitration. Peroxynitritc treatment of MnSOD (E. coli) caused nitration of tyrosine residues and loss of activity, but not dityrosinc formation. Considering high structural similarities of active centers of these two enzymes, observed differences arc surprising. Wc assume that different reactivity of MnSOD (E. coli) toward NO and ONOO- comparing to that of hMnSOD may be (partly) explained by higher flexibility of its (dimeric) structure comparing to that of hMnSOD, which is tetramer.",
publisher = "Turkish Biochemical Society",
journal = "Turkish Journal of Biochemistry",
title = "The effects of nitric oxide (NO) and peroxynitrite on MnSOD (E.coli)",
volume = "28",
number = "3",
pages = "116-117",
url = "https://hdl.handle.net/21.15107/rcub_cer_6535"
}

Stanić, D., Nikolić, M., Stojanović, S., Raičević, S.,& Niketić, V.. (2003). The effects of nitric oxide (NO) and peroxynitrite on MnSOD (E.coli). in Turkish Journal of Biochemistry
Turkish Biochemical Society., 28(3), 116-117.
https://hdl.handle.net/21.15107/rcub_cer_6535

Stanić D, Nikolić M, Stojanović S, Raičević S, Niketić V. The effects of nitric oxide (NO) and peroxynitrite on MnSOD (E.coli). in Turkish Journal of Biochemistry. 2003;28(3):116-117.
https://hdl.handle.net/21.15107/rcub_cer_6535 .

Stanić, Dragana, Nikolić, Milan, Stojanović, Srđan, Raičević, Smiljana, Niketić, Vesna, "The effects of nitric oxide (NO) and peroxynitrite on MnSOD (E.coli)" in Turkish Journal of Biochemistry, 28, no. 3 (2003):116-117,
https://hdl.handle.net/21.15107/rcub_cer_6535 .