Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200032 (Institute of Field and Vegetable Crops, Novi Sad)

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Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200032 (Institute of Field and Vegetable Crops, Novi Sad) (en)
Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije, Ugovor br. 451-03-68/2020-14/200032 (Naučni institut za ratarstvo i povrtarstvo, Novi Sad) (sr_RS)
Министарство просвете, науке и технолошког развоја Републике Србије, Уговор бр. 451-03-68/2020-14/200032 (Научни институт за ратарство и повртарство, Нови Сад) (sr)
Authors

Publications

Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts

Smiljanić, Katarina; Prodić, Ivana; Trifunović, Sara; Krstić-Ristivojević, Maja; Aćimović, Milica G.; Stanković Jeremić, Jovana; Lončar, Biljana; Tešević, Vele

(MDPI, 2023)

TY  - JOUR
AU  - Smiljanić, Katarina
AU  - Prodić, Ivana
AU  - Trifunović, Sara
AU  - Krstić-Ristivojević, Maja
AU  - Aćimović, Milica G.
AU  - Stanković Jeremić, Jovana
AU  - Lončar, Biljana
AU  - Tešević, Vele
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7198
AB  - As byproducts of essential oil distillation, hydrolates are used in natural cosmetics/biomedicine due to their beneficial skin effects. However, data on their safety with relevant biological targets, such as human skin cells, are scarce. Therefore, we have tested nine hydrolates from the Lamiaceae family with skin fibroblasts that are responsible for extracellular collagenous matrix builds. Thyme, oregano, and winter savoury hydrolates showed several times higher total phenolics, which correlated strongly with their radical scavenging and antioxidative capacity; there was no correlation between their viability profiles and the reducing sugar levels. No proteins/peptides were detected. All hydrolates appeared safe for prolonged skin exposure except for 10-fold diluted lavender, which showed cytotoxicity (~20%), as well as rosemary and lavandin (~10%) using viability, DNA synthesis, and cell count testing. Clary sage, oregano, lemon balm, and thyme hydrolates (10-fold diluted) increased fibroblast viability and/or proliferation by 10–30% compared with the control, while their viability remained unaffected by Mentha and winter savoury. In line with the STITCH database, increased viability could be attributed to thymol presence in oregano and thyme hydrolates in lemon balm, which is most likely attributable to neral and geranial. The proliferative effect of clary sage could be supported by alpha-terpineol, not linalool. The major volatile organic compounds (VOCs) associated with cytotoxic effects on fibroblasts were borneol, 1,8-cineole, and terpinene-4-ol. Further research with pure compounds is warranted to confirm the roles of VOCs in the observed effects that are relevant to cosmetic and wound healing aspects.
PB  - MDPI
T2  - Antioxidants
T1  - Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts
VL  - 12
IS  - 11
DO  - 10.3390/antiox12111988
ER  - 
@article{
author = "Smiljanić, Katarina and Prodić, Ivana and Trifunović, Sara and Krstić-Ristivojević, Maja and Aćimović, Milica G. and Stanković Jeremić, Jovana and Lončar, Biljana and Tešević, Vele",
year = "2023",
abstract = "As byproducts of essential oil distillation, hydrolates are used in natural cosmetics/biomedicine due to their beneficial skin effects. However, data on their safety with relevant biological targets, such as human skin cells, are scarce. Therefore, we have tested nine hydrolates from the Lamiaceae family with skin fibroblasts that are responsible for extracellular collagenous matrix builds. Thyme, oregano, and winter savoury hydrolates showed several times higher total phenolics, which correlated strongly with their radical scavenging and antioxidative capacity; there was no correlation between their viability profiles and the reducing sugar levels. No proteins/peptides were detected. All hydrolates appeared safe for prolonged skin exposure except for 10-fold diluted lavender, which showed cytotoxicity (~20%), as well as rosemary and lavandin (~10%) using viability, DNA synthesis, and cell count testing. Clary sage, oregano, lemon balm, and thyme hydrolates (10-fold diluted) increased fibroblast viability and/or proliferation by 10–30% compared with the control, while their viability remained unaffected by Mentha and winter savoury. In line with the STITCH database, increased viability could be attributed to thymol presence in oregano and thyme hydrolates in lemon balm, which is most likely attributable to neral and geranial. The proliferative effect of clary sage could be supported by alpha-terpineol, not linalool. The major volatile organic compounds (VOCs) associated with cytotoxic effects on fibroblasts were borneol, 1,8-cineole, and terpinene-4-ol. Further research with pure compounds is warranted to confirm the roles of VOCs in the observed effects that are relevant to cosmetic and wound healing aspects.",
publisher = "MDPI",
journal = "Antioxidants",
title = "Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts",
volume = "12",
number = "11",
doi = "10.3390/antiox12111988"
}
Smiljanić, K., Prodić, I., Trifunović, S., Krstić-Ristivojević, M., Aćimović, M. G., Stanković Jeremić, J., Lončar, B.,& Tešević, V.. (2023). Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts. in Antioxidants
MDPI., 12(11).
https://doi.org/10.3390/antiox12111988
Smiljanić K, Prodić I, Trifunović S, Krstić-Ristivojević M, Aćimović MG, Stanković Jeremić J, Lončar B, Tešević V. Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts. in Antioxidants. 2023;12(11).
doi:10.3390/antiox12111988 .
Smiljanić, Katarina, Prodić, Ivana, Trifunović, Sara, Krstić-Ristivojević, Maja, Aćimović, Milica G., Stanković Jeremić, Jovana, Lončar, Biljana, Tešević, Vele, "Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin Fibroblasts" in Antioxidants, 12, no. 11 (2023),
https://doi.org/10.3390/antiox12111988 . .
2
1

Screening of Volatile Compounds, Traditional and Modern Phytotherapy Approaches of Selected Non-Aromatic Medicinal Plants (Lamiaceae, Lamioideae) from Rtanj Mountain, Eastern Serbia

Aćimović, Milica; Stanković Jeremić, Jovana; Miljković, Ana; Rat, Milica; Lončar, Biljana

(Basel : MDPI, 2023)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Stanković Jeremić, Jovana
AU  - Miljković, Ana
AU  - Rat, Milica
AU  - Lončar, Biljana
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7200
AB  - Ironwort (Sideritis montana L.), mountain germander (Teucrium montanum L.), wall germander (Teucrium chamaedrys L.), and horehound (Marrubium peregrinum L.) are species widely distributedacross Europe and are also found in North Africa and West Asia. Because of their wide distributionthey express significant chemical diversity. For generations, these plants have been used as medicalherbs for treating different aliments. The aim of this paper is to analyze volatile compounds of fourselected species that belong to the subfamily Lamioideae, family Lamiaceae, and inspect scientificallyproven biological activities and potential uses in modern phytotherapy in relation to traditionalmedicine. Therefore, in this research, we analyze the volatile compounds from this plants, obtainedin laboratory by a Clevenger-type apparatus, followed by liquid–liquid extraction with hexane as thesolvent. The identification of volatile compounds is conducted by GC-FID and GC-MS. Althoughthese plants are poor in essential oil, the most abundant class of volatile components are mainlysesquiterpenes: germacrene D (22.6%) in ironwort, 7-epi-trans-sesquisabinene hydrate (15.8%) inmountain germander, germacrene D (31.8%) and trans-caryophyllene (19.7%) in wall germander, andtrans-caryophyllene (32.4%) and trans-thujone (25.1%) in horehound. Furthermore, many studiesshow that, in addition to the essential oil, these plants contain phenols, flavonoids, diterpenes andditerpenoids, iridoids and their glycosides, coumarins, terpenes, and sterols, among other activecompounds, which affect biological activities. The other goal of this study is to review the literaturethat describes the traditional use of these plants in folk medicine in regions where they grow spontaneously and compare them with scientifically confirmed activities. Therefore, a bibliographic searchis conducted on Science Direct, PubMed, and Google Scholar to gather information related to thetopic and recommend potential applications in modern phytotherapy. In conclusion, we can say thatselected plants could be used as natural agents for promoting health, as a source of raw materialin the food industry, and as supplements, as well as in the pharmaceutical industry for developingplant-based remedies for prevention and treatment of many diseases, especially cancer.
PB  - Basel : MDPI
T2  - Molecules - Basel
T1  - Screening of Volatile Compounds, Traditional and Modern Phytotherapy Approaches of Selected Non-Aromatic Medicinal Plants (Lamiaceae, Lamioideae) from Rtanj Mountain, Eastern Serbia
VL  - 28
IS  - 12
SP  - 4611
DO  - 10.3390/molecules28124611
ER  - 
@article{
author = "Aćimović, Milica and Stanković Jeremić, Jovana and Miljković, Ana and Rat, Milica and Lončar, Biljana",
year = "2023",
abstract = "Ironwort (Sideritis montana L.), mountain germander (Teucrium montanum L.), wall germander (Teucrium chamaedrys L.), and horehound (Marrubium peregrinum L.) are species widely distributedacross Europe and are also found in North Africa and West Asia. Because of their wide distributionthey express significant chemical diversity. For generations, these plants have been used as medicalherbs for treating different aliments. The aim of this paper is to analyze volatile compounds of fourselected species that belong to the subfamily Lamioideae, family Lamiaceae, and inspect scientificallyproven biological activities and potential uses in modern phytotherapy in relation to traditionalmedicine. Therefore, in this research, we analyze the volatile compounds from this plants, obtainedin laboratory by a Clevenger-type apparatus, followed by liquid–liquid extraction with hexane as thesolvent. The identification of volatile compounds is conducted by GC-FID and GC-MS. Althoughthese plants are poor in essential oil, the most abundant class of volatile components are mainlysesquiterpenes: germacrene D (22.6%) in ironwort, 7-epi-trans-sesquisabinene hydrate (15.8%) inmountain germander, germacrene D (31.8%) and trans-caryophyllene (19.7%) in wall germander, andtrans-caryophyllene (32.4%) and trans-thujone (25.1%) in horehound. Furthermore, many studiesshow that, in addition to the essential oil, these plants contain phenols, flavonoids, diterpenes andditerpenoids, iridoids and their glycosides, coumarins, terpenes, and sterols, among other activecompounds, which affect biological activities. The other goal of this study is to review the literaturethat describes the traditional use of these plants in folk medicine in regions where they grow spontaneously and compare them with scientifically confirmed activities. Therefore, a bibliographic searchis conducted on Science Direct, PubMed, and Google Scholar to gather information related to thetopic and recommend potential applications in modern phytotherapy. In conclusion, we can say thatselected plants could be used as natural agents for promoting health, as a source of raw materialin the food industry, and as supplements, as well as in the pharmaceutical industry for developingplant-based remedies for prevention and treatment of many diseases, especially cancer.",
publisher = "Basel : MDPI",
journal = "Molecules - Basel",
title = "Screening of Volatile Compounds, Traditional and Modern Phytotherapy Approaches of Selected Non-Aromatic Medicinal Plants (Lamiaceae, Lamioideae) from Rtanj Mountain, Eastern Serbia",
volume = "28",
number = "12",
pages = "4611",
doi = "10.3390/molecules28124611"
}
Aćimović, M., Stanković Jeremić, J., Miljković, A., Rat, M.,& Lončar, B.. (2023). Screening of Volatile Compounds, Traditional and Modern Phytotherapy Approaches of Selected Non-Aromatic Medicinal Plants (Lamiaceae, Lamioideae) from Rtanj Mountain, Eastern Serbia. in Molecules - Basel
Basel : MDPI., 28(12), 4611.
https://doi.org/10.3390/molecules28124611
Aćimović M, Stanković Jeremić J, Miljković A, Rat M, Lončar B. Screening of Volatile Compounds, Traditional and Modern Phytotherapy Approaches of Selected Non-Aromatic Medicinal Plants (Lamiaceae, Lamioideae) from Rtanj Mountain, Eastern Serbia. in Molecules - Basel. 2023;28(12):4611.
doi:10.3390/molecules28124611 .
Aćimović, Milica, Stanković Jeremić, Jovana, Miljković, Ana, Rat, Milica, Lončar, Biljana, "Screening of Volatile Compounds, Traditional and Modern Phytotherapy Approaches of Selected Non-Aromatic Medicinal Plants (Lamiaceae, Lamioideae) from Rtanj Mountain, Eastern Serbia" in Molecules - Basel, 28, no. 12 (2023):4611,
https://doi.org/10.3390/molecules28124611 . .
1
1
1

Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm

Aćimović, Milica; Semerdijeva, Ivanka; Zheljazkov, Valtcho D.; Rat, Milica; Stanković Jeremić, Jovana; Lončar, Biljana; Vukić, Vladimir; Radovanović, Katarina; Gavarić, Neda; Pezo, Lato

(Elsevier BV, 2023)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Semerdijeva, Ivanka
AU  - Zheljazkov, Valtcho D.
AU  - Rat, Milica
AU  - Stanković Jeremić, Jovana
AU  - Lončar, Biljana
AU  - Vukić, Vladimir
AU  - Radovanović, Katarina
AU  - Gavarić, Neda
AU  - Pezo, Lato
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6679
AB  - This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile. On the other hand, the results from Bulgaria show an evident chemical diversification within the A. clypeolata species, as 1,8-cineole (23.2%), camphor (5.0%) and borneol (8.9%) prevailed in the EO of the studied samples collected from Ivaylovgrad, while borneol (22.6%), β-eudesmol (12.7%) and elemol (7.8%) were the main ones in the EO from Dobrostan. In sillico analysis revealed the high anti-inflammatory potential of A. clypeolata, which may be highly diverse depending on the population and active compounds it contains.
PB  - Elsevier BV
T2  - Biochemical Systematics and Ecology
T1  - Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm
VL  - 110
SP  - 104679
DO  - 10.1016/j.bse.2023.104679
ER  - 
@article{
author = "Aćimović, Milica and Semerdijeva, Ivanka and Zheljazkov, Valtcho D. and Rat, Milica and Stanković Jeremić, Jovana and Lončar, Biljana and Vukić, Vladimir and Radovanović, Katarina and Gavarić, Neda and Pezo, Lato",
year = "2023",
abstract = "This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile. On the other hand, the results from Bulgaria show an evident chemical diversification within the A. clypeolata species, as 1,8-cineole (23.2%), camphor (5.0%) and borneol (8.9%) prevailed in the EO of the studied samples collected from Ivaylovgrad, while borneol (22.6%), β-eudesmol (12.7%) and elemol (7.8%) were the main ones in the EO from Dobrostan. In sillico analysis revealed the high anti-inflammatory potential of A. clypeolata, which may be highly diverse depending on the population and active compounds it contains.",
publisher = "Elsevier BV",
journal = "Biochemical Systematics and Ecology",
title = "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm",
volume = "110",
pages = "104679",
doi = "10.1016/j.bse.2023.104679"
}
Aćimović, M., Semerdijeva, I., Zheljazkov, V. D., Rat, M., Stanković Jeremić, J., Lončar, B., Vukić, V., Radovanović, K., Gavarić, N.,& Pezo, L.. (2023). Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology
Elsevier BV., 110, 104679.
https://doi.org/10.1016/j.bse.2023.104679
Aćimović M, Semerdijeva I, Zheljazkov VD, Rat M, Stanković Jeremić J, Lončar B, Vukić V, Radovanović K, Gavarić N, Pezo L. Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology. 2023;110:104679.
doi:10.1016/j.bse.2023.104679 .
Aćimović, Milica, Semerdijeva, Ivanka, Zheljazkov, Valtcho D., Rat, Milica, Stanković Jeremić, Jovana, Lončar, Biljana, Vukić, Vladimir, Radovanović, Katarina, Gavarić, Neda, Pezo, Lato, "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm" in Biochemical Systematics and Ecology, 110 (2023):104679,
https://doi.org/10.1016/j.bse.2023.104679 . .
1
1

Exploring the impact of transportation on heavy metal pollution: A comparative study of trains and cars

Stojić, Nataša; Štrbac, Snežana; Ćurčić, Ljiljana; Pucarević, Mira; Prokić, Dunja; Stepanov, Jasna; Stojić, Gordan

(Elsevier, 2023)

TY  - JOUR
AU  - Stojić, Nataša
AU  - Štrbac, Snežana
AU  - Ćurčić, Ljiljana
AU  - Pucarević, Mira
AU  - Prokić, Dunja
AU  - Stepanov, Jasna
AU  - Stojić, Gordan
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7174
AB  - This study aimed to investigate the impact of road and rail traffic on the soil through the analysisof the presence of heavy metals in soil samples collected next to a busy highway, local roads, andnext to an active railway line. Results showed that cars emitted higher levels of heavy metals thantrains. Soil samples near the highway had higher levels of Cu, Ni, and Hg. The values of thecalculated indices like geo-accumulation index, potential toxicity response index, ecological riskfactor, contamination factor, pollution load index, Nemerow’s pollution index, and degree ofcontamination confirm that the soil samples sampled near the highway are the most polluted andhighway have the greatest negative impact on the soil environment. These results suggest thatcontrolling car emissions through strict regulations and promoting public transportation couldeffectively reduce the heavy metal concentrations in soil, particularly from highway emissions.
PB  - Elsevier
T2  - Transportation Research Part D
T1  - Exploring the impact of transportation on heavy metal pollution: A comparative study of trains and cars
VL  - 125
SP  - 103966
DO  - 10.1016/j.trd.2023.103966
ER  - 
@article{
author = "Stojić, Nataša and Štrbac, Snežana and Ćurčić, Ljiljana and Pucarević, Mira and Prokić, Dunja and Stepanov, Jasna and Stojić, Gordan",
year = "2023",
abstract = "This study aimed to investigate the impact of road and rail traffic on the soil through the analysisof the presence of heavy metals in soil samples collected next to a busy highway, local roads, andnext to an active railway line. Results showed that cars emitted higher levels of heavy metals thantrains. Soil samples near the highway had higher levels of Cu, Ni, and Hg. The values of thecalculated indices like geo-accumulation index, potential toxicity response index, ecological riskfactor, contamination factor, pollution load index, Nemerow’s pollution index, and degree ofcontamination confirm that the soil samples sampled near the highway are the most polluted andhighway have the greatest negative impact on the soil environment. These results suggest thatcontrolling car emissions through strict regulations and promoting public transportation couldeffectively reduce the heavy metal concentrations in soil, particularly from highway emissions.",
publisher = "Elsevier",
journal = "Transportation Research Part D",
title = "Exploring the impact of transportation on heavy metal pollution: A comparative study of trains and cars",
volume = "125",
pages = "103966",
doi = "10.1016/j.trd.2023.103966"
}
Stojić, N., Štrbac, S., Ćurčić, L., Pucarević, M., Prokić, D., Stepanov, J.,& Stojić, G.. (2023). Exploring the impact of transportation on heavy metal pollution: A comparative study of trains and cars. in Transportation Research Part D
Elsevier., 125, 103966.
https://doi.org/10.1016/j.trd.2023.103966
Stojić N, Štrbac S, Ćurčić L, Pucarević M, Prokić D, Stepanov J, Stojić G. Exploring the impact of transportation on heavy metal pollution: A comparative study of trains and cars. in Transportation Research Part D. 2023;125:103966.
doi:10.1016/j.trd.2023.103966 .
Stojić, Nataša, Štrbac, Snežana, Ćurčić, Ljiljana, Pucarević, Mira, Prokić, Dunja, Stepanov, Jasna, Stojić, Gordan, "Exploring the impact of transportation on heavy metal pollution: A comparative study of trains and cars" in Transportation Research Part D, 125 (2023):103966,
https://doi.org/10.1016/j.trd.2023.103966 . .
2
2

Heavy metal concentrations in the soil near illegal landfills in the vicinity of agricultural areas—artificial neural network approach

Štrbac, Snežana; Stojić, Nataša; Lončar, Biljana; Pezo, Lato; Ćurčić, Ljiljana; Prokić, Dunja; Pucarević, Mira

(Springer Nature, 2023)

TY  - JOUR
AU  - Štrbac, Snežana
AU  - Stojić, Nataša
AU  - Lončar, Biljana
AU  - Pezo, Lato
AU  - Ćurčić, Ljiljana
AU  - Prokić, Dunja
AU  - Pucarević, Mira
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7173
AB  - Purpose To anticipate the impact of illegal landfills, development of new models should become a part of environmental risk management strategies. One of such approaches includes applications of the artificial neural network (ANN). The main objective of this study was to elucidate the impact of illegal landfilling on the surrounding soil environment and human health, as well as to establish an artificial neural network (ANN) models for predicting the hazards of illegal landfilling as an effective tool in decision-making and environmental risk management.Methods The identification of heavy metals source in soil was performed by principal component analysis (PCA). To assess the sensitivity of the soil ecosystem to heavy metal concentrations, Soil Quality standards and quantitative indices were used. The possible health effects were valued using the average daily doses (ADDs), hazard quotient (HQ), hazard index (HI), and carcinogenic risk (CR). ANN modeling was used for the prediction of heavy metal concentrations in the soil based on landfill size, municipality size, the number of residents, plant species, soil, and landform types.Results The average values of the pollution indexes for Cd were in the moderately contaminated and very high contamina tion categories. The HQ values were lower than the safe level. Cr and Pb posed a significant CR for adults and children, and Ni for children. The ANN models have exhibited good generalization power and accurately predicted the output parameters with a high value of the coefficient of determination.Conclusion Concerning heavy metal concentrations, illegal landfills near agricultural soil have a significant impact on the soil ecosystem and people’s health. The developed ANN models can be applied generally to anticipate the heavy metal concentrations in soil, according to the before mentioned input parameters, with high accuracy.
PB  - Springer Nature
T2  - Journal of Soils and Sediments
T1  - Heavy metal concentrations in the soil near illegal landfills in the vicinity of agricultural areas—artificial neural network approach
VL  - 23
IS  - 9
DO  - 10.1007/s11368-023-03637-1
ER  - 
@article{
author = "Štrbac, Snežana and Stojić, Nataša and Lončar, Biljana and Pezo, Lato and Ćurčić, Ljiljana and Prokić, Dunja and Pucarević, Mira",
year = "2023",
abstract = "Purpose To anticipate the impact of illegal landfills, development of new models should become a part of environmental risk management strategies. One of such approaches includes applications of the artificial neural network (ANN). The main objective of this study was to elucidate the impact of illegal landfilling on the surrounding soil environment and human health, as well as to establish an artificial neural network (ANN) models for predicting the hazards of illegal landfilling as an effective tool in decision-making and environmental risk management.Methods The identification of heavy metals source in soil was performed by principal component analysis (PCA). To assess the sensitivity of the soil ecosystem to heavy metal concentrations, Soil Quality standards and quantitative indices were used. The possible health effects were valued using the average daily doses (ADDs), hazard quotient (HQ), hazard index (HI), and carcinogenic risk (CR). ANN modeling was used for the prediction of heavy metal concentrations in the soil based on landfill size, municipality size, the number of residents, plant species, soil, and landform types.Results The average values of the pollution indexes for Cd were in the moderately contaminated and very high contamina tion categories. The HQ values were lower than the safe level. Cr and Pb posed a significant CR for adults and children, and Ni for children. The ANN models have exhibited good generalization power and accurately predicted the output parameters with a high value of the coefficient of determination.Conclusion Concerning heavy metal concentrations, illegal landfills near agricultural soil have a significant impact on the soil ecosystem and people’s health. The developed ANN models can be applied generally to anticipate the heavy metal concentrations in soil, according to the before mentioned input parameters, with high accuracy.",
publisher = "Springer Nature",
journal = "Journal of Soils and Sediments",
title = "Heavy metal concentrations in the soil near illegal landfills in the vicinity of agricultural areas—artificial neural network approach",
volume = "23",
number = "9",
doi = "10.1007/s11368-023-03637-1"
}
Štrbac, S., Stojić, N., Lončar, B., Pezo, L., Ćurčić, L., Prokić, D.,& Pucarević, M.. (2023). Heavy metal concentrations in the soil near illegal landfills in the vicinity of agricultural areas—artificial neural network approach. in Journal of Soils and Sediments
Springer Nature., 23(9).
https://doi.org/10.1007/s11368-023-03637-1
Štrbac S, Stojić N, Lončar B, Pezo L, Ćurčić L, Prokić D, Pucarević M. Heavy metal concentrations in the soil near illegal landfills in the vicinity of agricultural areas—artificial neural network approach. in Journal of Soils and Sediments. 2023;23(9).
doi:10.1007/s11368-023-03637-1 .
Štrbac, Snežana, Stojić, Nataša, Lončar, Biljana, Pezo, Lato, Ćurčić, Ljiljana, Prokić, Dunja, Pucarević, Mira, "Heavy metal concentrations in the soil near illegal landfills in the vicinity of agricultural areas—artificial neural network approach" in Journal of Soils and Sediments, 23, no. 9 (2023),
https://doi.org/10.1007/s11368-023-03637-1 . .
1
2

Persistent organic pollutants in soil samples from mountain beech forests across Europe

Štrbac, Snežana; Kašanin-Grubin, Milica; Stojić, Nataša; Pezo, Lato; Lončar, Biljana; Tognetti, Roberto; Pucarević, Mira

(Springer, 2023)

TY  - JOUR
AU  - Štrbac, Snežana
AU  - Kašanin-Grubin, Milica
AU  - Stojić, Nataša
AU  - Pezo, Lato
AU  - Lončar, Biljana
AU  - Tognetti, Roberto
AU  - Pucarević, Mira
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6805
AB  - Background and Aims: In the global distribution of persistent organic pollutants (POPs) forests play a key role due to the forest canopy effect. In this study, mountain beech forests were selected to identify the level and distribution of selected POPs. 
Methods: Organochlorine pesticides (OCPs) and polybrominated diphenyl ethers (PBDEs) were analyzed by capillary gas chromatography with an electron capture detector (GC–ECD). Analysis of polychlorinated biphenyls (PCBs) was performed by gas chromatography with a mass spectrometry detector (GC–MS). The polycyclic aromatic hydrocarbons (PAHs) were analyzed by liquid chromatography with a diode array detector (HPLC–DAD).
Results: The total ∑20OCP concentrations in the soil from mountain beech forests at a depth of 0 – 40 cm ranged from 24.46 μg kg −1 to 331.11 μg kg −1, and at a depth of 40 – 80 cm from 15.80 μg kg−1 to 247.12 μg kg −1. The mass concentration for ∑ 6PCB ranges from 9.21 to 95.28 μg kg−1 in the surface soil layer and from 8.07 to 66.56 μg kg −1 in the soil sub.layer. The total concentration of ∑7PBDE congeners measured in soil samples from mountain beech forests
across Europe was from 1.38 to 29.68 μg kg−1 in the surface soil layer and from 1.01 to 53.31 μg kg−1 in the soil sublayer. The total concentration of ∑ 16PAH varied from 271.52 to 1154.52 μg kg−1 in the surface soil layer and from 318.95 to 1052.54 μg kg −1 in the soil sublayer.
Conclusion: The results of this study can serve as an important basis for international, national, and regional measures of environmental protection of beech forests from POPs pollution.
PB  - Springer
T2  - Plant and Soil
T1  - Persistent organic pollutants in soil samples from mountain beech forests across Europe
DO  - 10.1007/s11104-023-06329-4
ER  - 
@article{
author = "Štrbac, Snežana and Kašanin-Grubin, Milica and Stojić, Nataša and Pezo, Lato and Lončar, Biljana and Tognetti, Roberto and Pucarević, Mira",
year = "2023",
abstract = "Background and Aims: In the global distribution of persistent organic pollutants (POPs) forests play a key role due to the forest canopy effect. In this study, mountain beech forests were selected to identify the level and distribution of selected POPs. 
Methods: Organochlorine pesticides (OCPs) and polybrominated diphenyl ethers (PBDEs) were analyzed by capillary gas chromatography with an electron capture detector (GC–ECD). Analysis of polychlorinated biphenyls (PCBs) was performed by gas chromatography with a mass spectrometry detector (GC–MS). The polycyclic aromatic hydrocarbons (PAHs) were analyzed by liquid chromatography with a diode array detector (HPLC–DAD).
Results: The total ∑20OCP concentrations in the soil from mountain beech forests at a depth of 0 – 40 cm ranged from 24.46 μg kg −1 to 331.11 μg kg −1, and at a depth of 40 – 80 cm from 15.80 μg kg−1 to 247.12 μg kg −1. The mass concentration for ∑ 6PCB ranges from 9.21 to 95.28 μg kg−1 in the surface soil layer and from 8.07 to 66.56 μg kg −1 in the soil sub.layer. The total concentration of ∑7PBDE congeners measured in soil samples from mountain beech forests
across Europe was from 1.38 to 29.68 μg kg−1 in the surface soil layer and from 1.01 to 53.31 μg kg−1 in the soil sublayer. The total concentration of ∑ 16PAH varied from 271.52 to 1154.52 μg kg−1 in the surface soil layer and from 318.95 to 1052.54 μg kg −1 in the soil sublayer.
Conclusion: The results of this study can serve as an important basis for international, national, and regional measures of environmental protection of beech forests from POPs pollution.",
publisher = "Springer",
journal = "Plant and Soil",
title = "Persistent organic pollutants in soil samples from mountain beech forests across Europe",
doi = "10.1007/s11104-023-06329-4"
}
Štrbac, S., Kašanin-Grubin, M., Stojić, N., Pezo, L., Lončar, B., Tognetti, R.,& Pucarević, M.. (2023). Persistent organic pollutants in soil samples from mountain beech forests across Europe. in Plant and Soil
Springer..
https://doi.org/10.1007/s11104-023-06329-4
Štrbac S, Kašanin-Grubin M, Stojić N, Pezo L, Lončar B, Tognetti R, Pucarević M. Persistent organic pollutants in soil samples from mountain beech forests across Europe. in Plant and Soil. 2023;.
doi:10.1007/s11104-023-06329-4 .
Štrbac, Snežana, Kašanin-Grubin, Milica, Stojić, Nataša, Pezo, Lato, Lončar, Biljana, Tognetti, Roberto, Pucarević, Mira, "Persistent organic pollutants in soil samples from mountain beech forests across Europe" in Plant and Soil (2023),
https://doi.org/10.1007/s11104-023-06329-4 . .

Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia)

Aćimović, Milica; Lončar, Biljana; Pezo, Milada; Stanković Jeremić, Jovana; Cvetković, Mirjana; Rat, Milica; Pezo, Lato

(2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Lončar, Biljana
AU  - Pezo, Milada
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
AU  - Rat, Milica
AU  - Pezo, Lato
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5265
AB  - Unlike other studies that only determined the chemical composition of essential oils depending on their geographic origin, this research investigated the effect of weather conditions (temperature, precipitation, and insolation) on the chemical composition of Nepeta nuda L. essential oil. The collection of wild-growing N. nuda was carried out during three successive years, 2019, 2020, and 2021 at Rtanj Mountain (Serbia) on the same date (July 7th). Essential oil extraction from the plant was performed by hydro-distillation. After gas chromatographic-mass spectrometric analysis, a total of 102 volatile compounds were separated from N. nuda, during the observed period, 28 were unidentified, compromising between 5.0% and 8.7%, depending on the year. A multiple linear regression model was created, and statistical analyses were performed to provide knowledge about the prediction, feature profile, and the similarity in contents of active compounds of the N. nuda essential oil. The influence of temperature on the accumulation of the most abundant component, 1,8-cineole, was positive, while the impact of precipitation and insolation was negative. According to the cluster tree, there are four chemotypes of N. nuda essential oil: with nepetalactone, 1,8-cineole, mixed (nepetalactone+1,8-cineole+germacrene D), and nonspecific chemotypes. Bearing in mind that the biological activity of a raw material depends on the chemotype and environmental factors, this is a topic that deserves a more detailed approach. The N. nuda and its essential oil are promising materials with high biological potential, and these deserve further detailed investigation.
T2  - Horticulturae
T1  - Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia)
VL  - 8
IS  - 2
SP  - 85
DO  - 10.3390/horticulturae8020085
ER  - 
@article{
author = "Aćimović, Milica and Lončar, Biljana and Pezo, Milada and Stanković Jeremić, Jovana and Cvetković, Mirjana and Rat, Milica and Pezo, Lato",
year = "2022",
abstract = "Unlike other studies that only determined the chemical composition of essential oils depending on their geographic origin, this research investigated the effect of weather conditions (temperature, precipitation, and insolation) on the chemical composition of Nepeta nuda L. essential oil. The collection of wild-growing N. nuda was carried out during three successive years, 2019, 2020, and 2021 at Rtanj Mountain (Serbia) on the same date (July 7th). Essential oil extraction from the plant was performed by hydro-distillation. After gas chromatographic-mass spectrometric analysis, a total of 102 volatile compounds were separated from N. nuda, during the observed period, 28 were unidentified, compromising between 5.0% and 8.7%, depending on the year. A multiple linear regression model was created, and statistical analyses were performed to provide knowledge about the prediction, feature profile, and the similarity in contents of active compounds of the N. nuda essential oil. The influence of temperature on the accumulation of the most abundant component, 1,8-cineole, was positive, while the impact of precipitation and insolation was negative. According to the cluster tree, there are four chemotypes of N. nuda essential oil: with nepetalactone, 1,8-cineole, mixed (nepetalactone+1,8-cineole+germacrene D), and nonspecific chemotypes. Bearing in mind that the biological activity of a raw material depends on the chemotype and environmental factors, this is a topic that deserves a more detailed approach. The N. nuda and its essential oil are promising materials with high biological potential, and these deserve further detailed investigation.",
journal = "Horticulturae",
title = "Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia)",
volume = "8",
number = "2",
pages = "85",
doi = "10.3390/horticulturae8020085"
}
Aćimović, M., Lončar, B., Pezo, M., Stanković Jeremić, J., Cvetković, M., Rat, M.,& Pezo, L.. (2022). Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia). in Horticulturae, 8(2), 85.
https://doi.org/10.3390/horticulturae8020085
Aćimović M, Lončar B, Pezo M, Stanković Jeremić J, Cvetković M, Rat M, Pezo L. Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia). in Horticulturae. 2022;8(2):85.
doi:10.3390/horticulturae8020085 .
Aćimović, Milica, Lončar, Biljana, Pezo, Milada, Stanković Jeremić, Jovana, Cvetković, Mirjana, Rat, Milica, Pezo, Lato, "Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia)" in Horticulturae, 8, no. 2 (2022):85,
https://doi.org/10.3390/horticulturae8020085 . .
1
8
2
10

Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools

Aćimović, Milica; Cvetković, Mirjana; Stanković Jeremić, Jovana; Pezo, Lato; Varga, Ana; Čabarkapa, Ivana; Kiprovski, Biljana

(Wiley, 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Cvetković, Mirjana
AU  - Stanković Jeremić, Jovana
AU  - Pezo, Lato
AU  - Varga, Ana
AU  - Čabarkapa, Ivana
AU  - Kiprovski, Biljana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5406
AB  - Salvia sclarea L. or clary sage is cultivated worldwide in temperate and sub-tropical climates, as an ornamental and essential oil (EO) bearing plant. EO is obtained from fresh spikes in full flowering stage and is recognized as an important commercial product for food, beverage and cosmetic industries. This study investigated the EO composition of S. sclarea grown in Serbia (Southeast Europe) obtained by two different methods, steam (SD) and hydrodistillation (HD). GC-MS analysis identified oxygenated monoterpenes as the main class of compounds for all EOs (between 81.8% and 88.2% depending on the distillation process). The most abundant oxygenated monoterpenes were linalyl acetate and linalool. In addition, in vitro antimicrobial (modified resazurin microtitre-plate assay) and antioxidant activities (DPPH• assay) and total polyphenol content of obtained EOs were also evaluated. According to the assay used for the evaluation of the antibacterial activity, Gram-negative bacteria were more sensitive to S. sclarea EO in comparison to Gram-positive bacteria. EOs exhibited low antioxidant capacity, below 3% neutralized DPPH• radicals, reaching up to approximately 400 µg AAE mL-1. This study also investigated a possibility for predicting retention indices (RIs) of compounds isolated from EOs. In total, 78 experimentally obtained RIs were applied to construct the prediction model. The quantitative structure-chromatographic retention relationship (QSRR) model was used to anticipate the experimentally obtained RIs. Five molecular descriptors were selected by factor analysis and genetic algorithm to predict RIs. The obtained accuracy of the QSRR model reached r2 =.912, which showed that these models might be applied for predicting retention indices.
PB  - Wiley
T2  - Flavour and Fragrance Journal
T1  - Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools
VL  - 37
IS  - 1
SP  - 20
EP  - 32
DO  - 10.1002/ffj.3684
ER  - 
@article{
author = "Aćimović, Milica and Cvetković, Mirjana and Stanković Jeremić, Jovana and Pezo, Lato and Varga, Ana and Čabarkapa, Ivana and Kiprovski, Biljana",
year = "2022",
abstract = "Salvia sclarea L. or clary sage is cultivated worldwide in temperate and sub-tropical climates, as an ornamental and essential oil (EO) bearing plant. EO is obtained from fresh spikes in full flowering stage and is recognized as an important commercial product for food, beverage and cosmetic industries. This study investigated the EO composition of S. sclarea grown in Serbia (Southeast Europe) obtained by two different methods, steam (SD) and hydrodistillation (HD). GC-MS analysis identified oxygenated monoterpenes as the main class of compounds for all EOs (between 81.8% and 88.2% depending on the distillation process). The most abundant oxygenated monoterpenes were linalyl acetate and linalool. In addition, in vitro antimicrobial (modified resazurin microtitre-plate assay) and antioxidant activities (DPPH• assay) and total polyphenol content of obtained EOs were also evaluated. According to the assay used for the evaluation of the antibacterial activity, Gram-negative bacteria were more sensitive to S. sclarea EO in comparison to Gram-positive bacteria. EOs exhibited low antioxidant capacity, below 3% neutralized DPPH• radicals, reaching up to approximately 400 µg AAE mL-1. This study also investigated a possibility for predicting retention indices (RIs) of compounds isolated from EOs. In total, 78 experimentally obtained RIs were applied to construct the prediction model. The quantitative structure-chromatographic retention relationship (QSRR) model was used to anticipate the experimentally obtained RIs. Five molecular descriptors were selected by factor analysis and genetic algorithm to predict RIs. The obtained accuracy of the QSRR model reached r2 =.912, which showed that these models might be applied for predicting retention indices.",
publisher = "Wiley",
journal = "Flavour and Fragrance Journal",
title = "Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools",
volume = "37",
number = "1",
pages = "20-32",
doi = "10.1002/ffj.3684"
}
Aćimović, M., Cvetković, M., Stanković Jeremić, J., Pezo, L., Varga, A., Čabarkapa, I.,& Kiprovski, B.. (2022). Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools. in Flavour and Fragrance Journal
Wiley., 37(1), 20-32.
https://doi.org/10.1002/ffj.3684
Aćimović M, Cvetković M, Stanković Jeremić J, Pezo L, Varga A, Čabarkapa I, Kiprovski B. Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools. in Flavour and Fragrance Journal. 2022;37(1):20-32.
doi:10.1002/ffj.3684 .
Aćimović, Milica, Cvetković, Mirjana, Stanković Jeremić, Jovana, Pezo, Lato, Varga, Ana, Čabarkapa, Ivana, Kiprovski, Biljana, "Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools" in Flavour and Fragrance Journal, 37, no. 1 (2022):20-32,
https://doi.org/10.1002/ffj.3684 . .
3
24
2
22

Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia

Aćimović, Milica; Stanković Jeremić, Jovana; Todosijević, Marina; Kiprovski, Biljana; Vidović, Senka; Vladić, Jelena; Pezo, Lato

(Wiley, 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Stanković Jeremić, Jovana
AU  - Todosijević, Marina
AU  - Kiprovski, Biljana
AU  - Vidović, Senka
AU  - Vladić, Jelena
AU  - Pezo, Lato
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5407
AB  - The most abundant volatile compounds of sweet wormwood (Artemisia annua L.) essential oil were artemisia ketone (25.4 %) and trans-caryophyllene (10.2 %), followed by 1,8-cineole, camphor, germacrene D and β-selinene. The major volatile compounds in the hydrosol were camphor (25.1 %), 1,8-cineole (20.5 %) and artemisia ketone (10.7 %), followed by trans-pinocarveol and yomogi alcohol. Tested essential oil was rich in oxygenated monoterpenes and sesquiterpene hydrocarbons, while the former were identified as the major class of volatile compounds in the hydrosol, due to higher water solubility. Classification of all sweet wormwood chemotypes, according to essential oil composition, in available literature (17 studies and 61 accessions) could be done according to four chemotypes: artemisia ketone+artemisia alcohol (most abundant), artemisia ketone, camphor and nonspecific chemotype. According to this classification, essential oil of sweet wormwood from this study belongs to artemisia ketone (content varied between 22.1 and 55.8 %). Bearing in mind that hydrosols are a by-product of industrial production of essential oils, and the fact that sweet wormwood hydrosol has high contents of camphor, 1,8-cineole and artemisia ketone, there is a great potential for the use of this aromatic plant primary processing waste product as a water replacement in cosmetic industry, beverages flavoring, for food preservation, as well as in post-harvest pre-storage treatments in organic agriculture.
PB  - Wiley
T2  - Chemistry and Biodiversity
T1  - Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia
VL  - 19
IS  - 3
SP  - e202100954
DO  - 10.1002/cbdv.202100954
ER  - 
@article{
author = "Aćimović, Milica and Stanković Jeremić, Jovana and Todosijević, Marina and Kiprovski, Biljana and Vidović, Senka and Vladić, Jelena and Pezo, Lato",
year = "2022",
abstract = "The most abundant volatile compounds of sweet wormwood (Artemisia annua L.) essential oil were artemisia ketone (25.4 %) and trans-caryophyllene (10.2 %), followed by 1,8-cineole, camphor, germacrene D and β-selinene. The major volatile compounds in the hydrosol were camphor (25.1 %), 1,8-cineole (20.5 %) and artemisia ketone (10.7 %), followed by trans-pinocarveol and yomogi alcohol. Tested essential oil was rich in oxygenated monoterpenes and sesquiterpene hydrocarbons, while the former were identified as the major class of volatile compounds in the hydrosol, due to higher water solubility. Classification of all sweet wormwood chemotypes, according to essential oil composition, in available literature (17 studies and 61 accessions) could be done according to four chemotypes: artemisia ketone+artemisia alcohol (most abundant), artemisia ketone, camphor and nonspecific chemotype. According to this classification, essential oil of sweet wormwood from this study belongs to artemisia ketone (content varied between 22.1 and 55.8 %). Bearing in mind that hydrosols are a by-product of industrial production of essential oils, and the fact that sweet wormwood hydrosol has high contents of camphor, 1,8-cineole and artemisia ketone, there is a great potential for the use of this aromatic plant primary processing waste product as a water replacement in cosmetic industry, beverages flavoring, for food preservation, as well as in post-harvest pre-storage treatments in organic agriculture.",
publisher = "Wiley",
journal = "Chemistry and Biodiversity",
title = "Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia",
volume = "19",
number = "3",
pages = "e202100954",
doi = "10.1002/cbdv.202100954"
}
Aćimović, M., Stanković Jeremić, J., Todosijević, M., Kiprovski, B., Vidović, S., Vladić, J.,& Pezo, L.. (2022). Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia. in Chemistry and Biodiversity
Wiley., 19(3), e202100954.
https://doi.org/10.1002/cbdv.202100954
Aćimović M, Stanković Jeremić J, Todosijević M, Kiprovski B, Vidović S, Vladić J, Pezo L. Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia. in Chemistry and Biodiversity. 2022;19(3):e202100954.
doi:10.1002/cbdv.202100954 .
Aćimović, Milica, Stanković Jeremić, Jovana, Todosijević, Marina, Kiprovski, Biljana, Vidović, Senka, Vladić, Jelena, Pezo, Lato, "Comparative Study of the Essential Oil and Hydrosol Composition of Sweet Wormwood (Artemisia annua L.) from Serbia" in Chemistry and Biodiversity, 19, no. 3 (2022):e202100954,
https://doi.org/10.1002/cbdv.202100954 . .
2
14
11

Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality

Aćimović, Milica; Lončar, Biljana; Stanković Jeremić, Jovana; Cvetković, Mirjana; Pezo, Lato; Pezo, Milada; Todosijević, Marina; Tešević, Vele

(Switzerland : Multidisciplinary Digital Publishing Institute (MDPI), 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Lončar, Biljana
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
AU  - Pezo, Lato
AU  - Pezo, Milada
AU  - Todosijević, Marina
AU  - Tešević, Vele
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5409
AB  - Lavandula sp. essential oil and hydrolate are commercially valuable in various industry
branches with the potential for wide-ranging applications. This study aimed to evaluate the quality
of these products obtained from L. x intermedia cv. ‘Budrovka’ for the first time cultivated on Fruška
Gora Mt. (Serbia) during three successive seasons (2019, 2020, and 2021). Essential oil extraction
was obtained by steam distillation, and the composition and influence of weather conditions were
also assessed, using flowering tops. The obtained essential oils and hydrolates were analysed by
gas chromatography with a flame ionization detector (GC-FID) and gas chromatography coupled to
mass spectrometry (GC-MS). A linear regression model was developed to predict L. x intermedia cv.
‘Budrovka’ essential oil volatile compound content and hydrolate composition during three years,
according to temperature and precipitation data, and the appropriate regression coefficients were
calculated, while the correlation analysis was employed to analyse the correlations in hydrolate
and essential oil compounds. To completely describe the structure of the research data that would
present a better insight into the similarities and differences among the diverse L. x intermedia cv.
‘Budrovka’ samples, the PCA was used. The most dominant in L. intermedia cv. ‘Budrovka’ essential
oil and hydrolate were oxygenated monoterpenes: linalool, 1,8-cineole, borneol, linalyl acetate, and
terpinene-4-ol. It is established that the temperature was positively correlated with all essential oil
and hydrolate compounds. The precipitations were positively correlated with the main compounds
(linalool, 1,8-cineole, and borneol), while the other compounds’ content negatively correlated to
precipitation. The results indicated that Fruška Gora Mt. has suitable agro-ecological requirements
for cultivating Lavandula sp. and providing satisfactory essential oil and hydrolate.
PB  - Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)
T2  - Horticulturae
T1  - Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality
VL  - 8
SP  - 281
DO  - 10.3390/horticulturae8040281
ER  - 
@article{
author = "Aćimović, Milica and Lončar, Biljana and Stanković Jeremić, Jovana and Cvetković, Mirjana and Pezo, Lato and Pezo, Milada and Todosijević, Marina and Tešević, Vele",
year = "2022",
abstract = "Lavandula sp. essential oil and hydrolate are commercially valuable in various industry
branches with the potential for wide-ranging applications. This study aimed to evaluate the quality
of these products obtained from L. x intermedia cv. ‘Budrovka’ for the first time cultivated on Fruška
Gora Mt. (Serbia) during three successive seasons (2019, 2020, and 2021). Essential oil extraction
was obtained by steam distillation, and the composition and influence of weather conditions were
also assessed, using flowering tops. The obtained essential oils and hydrolates were analysed by
gas chromatography with a flame ionization detector (GC-FID) and gas chromatography coupled to
mass spectrometry (GC-MS). A linear regression model was developed to predict L. x intermedia cv.
‘Budrovka’ essential oil volatile compound content and hydrolate composition during three years,
according to temperature and precipitation data, and the appropriate regression coefficients were
calculated, while the correlation analysis was employed to analyse the correlations in hydrolate
and essential oil compounds. To completely describe the structure of the research data that would
present a better insight into the similarities and differences among the diverse L. x intermedia cv.
‘Budrovka’ samples, the PCA was used. The most dominant in L. intermedia cv. ‘Budrovka’ essential
oil and hydrolate were oxygenated monoterpenes: linalool, 1,8-cineole, borneol, linalyl acetate, and
terpinene-4-ol. It is established that the temperature was positively correlated with all essential oil
and hydrolate compounds. The precipitations were positively correlated with the main compounds
(linalool, 1,8-cineole, and borneol), while the other compounds’ content negatively correlated to
precipitation. The results indicated that Fruška Gora Mt. has suitable agro-ecological requirements
for cultivating Lavandula sp. and providing satisfactory essential oil and hydrolate.",
publisher = "Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "Horticulturae",
title = "Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality",
volume = "8",
pages = "281",
doi = "10.3390/horticulturae8040281"
}
Aćimović, M., Lončar, B., Stanković Jeremić, J., Cvetković, M., Pezo, L., Pezo, M., Todosijević, M.,& Tešević, V.. (2022). Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality. in Horticulturae
Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)., 8, 281.
https://doi.org/10.3390/horticulturae8040281
Aćimović M, Lončar B, Stanković Jeremić J, Cvetković M, Pezo L, Pezo M, Todosijević M, Tešević V. Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality. in Horticulturae. 2022;8:281.
doi:10.3390/horticulturae8040281 .
Aćimović, Milica, Lončar, Biljana, Stanković Jeremić, Jovana, Cvetković, Mirjana, Pezo, Lato, Pezo, Milada, Todosijević, Marina, Tešević, Vele, "Weather Conditions Influence on Lavandin Essential Oil and Hydrolate Quality" in Horticulturae, 8 (2022):281,
https://doi.org/10.3390/horticulturae8040281 . .
1
18
2
16

Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity

Aćimović, Milica; Pezo, Lato; Čabarkapa, Ivana; Trudić, Anika; Stanković Jeremić, Jovana; Varga, Ana; Lončar, Biljana; Šovljanski, Olja; Tešević, Vele

(MDPI AG, 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Trudić, Anika
AU  - Stanković Jeremić, Jovana
AU  - Varga, Ana
AU  - Lončar, Biljana
AU  - Šovljanski, Olja
AU  - Tešević, Vele
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5587
AB  - This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cis-thujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 μL mL−1, respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 μL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 μL mL−1. Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.
PB  - MDPI AG
T2  - Processes
T1  - Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity
VL  - 10
IS  - 8
SP  - 1608
DO  - 10.3390/pr10081608
ER  - 
@article{
author = "Aćimović, Milica and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele",
year = "2022",
abstract = "This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cis-thujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 μL mL−1, respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 μL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 μL mL−1. Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.",
publisher = "MDPI AG",
journal = "Processes",
title = "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity",
volume = "10",
number = "8",
pages = "1608",
doi = "10.3390/pr10081608"
}
Aćimović, M., Pezo, L., Čabarkapa, I., Trudić, A., Stanković Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes
MDPI AG., 10(8), 1608.
https://doi.org/10.3390/pr10081608
Aćimović M, Pezo L, Čabarkapa I, Trudić A, Stanković Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes. 2022;10(8):1608.
doi:10.3390/pr10081608 .
Aćimović, Milica, Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity" in Processes, 10, no. 8 (2022):1608,
https://doi.org/10.3390/pr10081608 . .
5
5

Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy

Miletić, Srđan; Stojić, Nataša; Teofilović, Vesna; Živković, Milica; Avdalović, Jelena; Pucarević, Mira; Vrvić, Miroslav

(2022)

TY  - CONF
AU  - Miletić, Srđan
AU  - Stojić, Nataša
AU  - Teofilović, Vesna
AU  - Živković, Milica
AU  - Avdalović, Jelena
AU  - Pucarević, Mira
AU  - Vrvić, Miroslav
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5411
AB  - Poster presented at: The 24th International Biohydrometallurgy Symposium (IBS) 20/11 2022
T1  - Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy
UR  - https://hdl.handle.net/21.15107/rcub_cer_5411
ER  - 
@conference{
author = "Miletić, Srđan and Stojić, Nataša and Teofilović, Vesna and Živković, Milica and Avdalović, Jelena and Pucarević, Mira and Vrvić, Miroslav",
year = "2022",
abstract = "Poster presented at: The 24th International Biohydrometallurgy Symposium (IBS) 20/11 2022",
title = "Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy",
url = "https://hdl.handle.net/21.15107/rcub_cer_5411"
}
Miletić, S., Stojić, N., Teofilović, V., Živković, M., Avdalović, J., Pucarević, M.,& Vrvić, M.. (2022). Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy. .
https://hdl.handle.net/21.15107/rcub_cer_5411
Miletić S, Stojić N, Teofilović V, Živković M, Avdalović J, Pucarević M, Vrvić M. Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy. 2022;.
https://hdl.handle.net/21.15107/rcub_cer_5411 .
Miletić, Srđan, Stojić, Nataša, Teofilović, Vesna, Živković, Milica, Avdalović, Jelena, Pucarević, Mira, Vrvić, Miroslav, "Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy" (2022),
https://hdl.handle.net/21.15107/rcub_cer_5411 .

Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy

Miletić, Srđan; Stojić, Nataša; Teofilović, Vesna; Živković, Milica; Avdalović, Jelena; Pucarević, Mira; Vrvić, Miroslav

(Commonwealth Scientific and Industrial Research Organisation (CSIRO), 2022)

TY  - CONF
AU  - Miletić, Srđan
AU  - Stojić, Nataša
AU  - Teofilović, Vesna
AU  - Živković, Milica
AU  - Avdalović, Jelena
AU  - Pucarević, Mira
AU  - Vrvić, Miroslav
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5410
AB  - In this study the ex-situ bioremediation of waste heavy residual oil fuel was examined.
Microbial consortium was isolated from the polluted site at Belgrade Heating Plants (Serbia) and was added to the projected biopile. The nutrients, aeration-periodic mixing was used during process. The biopile was inoculated and biostimulated for 150 days. As a result, the total petroleum hydrocarbons (TPH) decreased by approximately 80 times. Also, the content of humic acids increased which indicated
the beginning of pedogenesis phase – soil formation (soilification). Level of humic acids during process at the end is higher about 40%. Also, bioremediation microorganisms from the inorganic matrix (river sand) generate clay minerals (content increases by about 50%) which are characteristic of the soil. At the same time, due to the microbial generation of organic acids, the concentration of carbonate
minerals from sand (calcite and dolomite) decreases. All these indicators confirm the efficiency of bioremediation and the simultaneous formation of man-made soil (MMS) as new resource for agriculture, landscaping and reforestation. The obtained soil was used for the stabilization of municipal waste as an overlay at this time. In conclusion: bioremediation that generates some useful geo-material
is a great example of a circular economy that is different from the usual ones (such as aluminum can and paper recycling).
PB  - Commonwealth Scientific and Industrial Research Organisation (CSIRO)
C3  - Book of abstracts - The 24th International Biohydrometallurgy Symposium (IBS) 20/11 2022
T1  - Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy
SP  - 149
EP  - 149
UR  - https://hdl.handle.net/21.15107/rcub_cer_5410
ER  - 
@conference{
author = "Miletić, Srđan and Stojić, Nataša and Teofilović, Vesna and Živković, Milica and Avdalović, Jelena and Pucarević, Mira and Vrvić, Miroslav",
year = "2022",
abstract = "In this study the ex-situ bioremediation of waste heavy residual oil fuel was examined.
Microbial consortium was isolated from the polluted site at Belgrade Heating Plants (Serbia) and was added to the projected biopile. The nutrients, aeration-periodic mixing was used during process. The biopile was inoculated and biostimulated for 150 days. As a result, the total petroleum hydrocarbons (TPH) decreased by approximately 80 times. Also, the content of humic acids increased which indicated
the beginning of pedogenesis phase – soil formation (soilification). Level of humic acids during process at the end is higher about 40%. Also, bioremediation microorganisms from the inorganic matrix (river sand) generate clay minerals (content increases by about 50%) which are characteristic of the soil. At the same time, due to the microbial generation of organic acids, the concentration of carbonate
minerals from sand (calcite and dolomite) decreases. All these indicators confirm the efficiency of bioremediation and the simultaneous formation of man-made soil (MMS) as new resource for agriculture, landscaping and reforestation. The obtained soil was used for the stabilization of municipal waste as an overlay at this time. In conclusion: bioremediation that generates some useful geo-material
is a great example of a circular economy that is different from the usual ones (such as aluminum can and paper recycling).",
publisher = "Commonwealth Scientific and Industrial Research Organisation (CSIRO)",
journal = "Book of abstracts - The 24th International Biohydrometallurgy Symposium (IBS) 20/11 2022",
title = "Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy",
pages = "149-149",
url = "https://hdl.handle.net/21.15107/rcub_cer_5410"
}
Miletić, S., Stojić, N., Teofilović, V., Živković, M., Avdalović, J., Pucarević, M.,& Vrvić, M.. (2022). Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy. in Book of abstracts - The 24th International Biohydrometallurgy Symposium (IBS) 20/11 2022
Commonwealth Scientific and Industrial Research Organisation (CSIRO)., 149-149.
https://hdl.handle.net/21.15107/rcub_cer_5410
Miletić S, Stojić N, Teofilović V, Živković M, Avdalović J, Pucarević M, Vrvić M. Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy. in Book of abstracts - The 24th International Biohydrometallurgy Symposium (IBS) 20/11 2022. 2022;:149-149.
https://hdl.handle.net/21.15107/rcub_cer_5410 .
Miletić, Srđan, Stojić, Nataša, Teofilović, Vesna, Živković, Milica, Avdalović, Jelena, Pucarević, Mira, Vrvić, Miroslav, "Microbial bioremediation of residual heavy oil waste from power plants (Serbia) and its reuse: example of circular economy" in Book of abstracts - The 24th International Biohydrometallurgy Symposium (IBS) 20/11 2022 (2022):149-149,
https://hdl.handle.net/21.15107/rcub_cer_5410 .

Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities

Aćimović, Milica; Šeregelj, Vanja; Simić, Katarina; Varga, Ana; Pezo, Lato; Vulić, Jelena; Čabarkapa, Ivana

(Lublin : Uniwersytetu Przyrodniczego Lublin, 2022)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Šeregelj, Vanja
AU  - Simić, Katarina
AU  - Varga, Ana
AU  - Pezo, Lato
AU  - Vulić, Jelena
AU  - Čabarkapa, Ivana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5353
AB  - Essential oil (EO) obtained by hydrodistillation in a Clevenger-type apparatus from aerial parts of Nepeta cataria L. var. citriodora (Becker), cultivated in Serbia was subjected to gas chromatography-mass spectroscopy (GC-MS) to determine the composition. Furthermore, N. cataria var. citriodora essential oil was
tested to determine its antimicrobial, antioxidant, antihyperglycemic and anti-inflammatory activities in vitro.
The antimicrobial activity was tested by broth microdilution method against 16 bacterial strains from American Type Culture Collection (ATCC). Four common tests for measuring in vitro antioxidant activity were used: 2, 2-diphenyl-1-picrylhydrazyl assay (DPPH), reducing power (RP), 2,2-azino-bis-3-ethylbenzothiazoline-
6-sulfonic acid (ABTS) and β-carotene bleaching assay (BCB). Antihyperglycemic activity was examined by using α-glucosidase inhibitory potential (AHgA), while anti-inflammatory activity (AIA) was determined by protein denaturation bioassay, using egg albumin. In total, 36 compounds were isolated and detected by GC-MS technique in N. cataria var. citriodora EO. The EO is mainly comprised of oxygenated monoterpenes (93.1%), and the main compounds were two monoterpenoid alcohols, nerol (38.5%) and geraniol (24.9%), followed by two aliphatic aldehyde, geranial (14.6%) and neral (11.0%). Antimicrobial activity of this EO shows growth inhibition of all tested bacteria strains, and exhibited good antioxidant, antihyperglycemic and anti-inflammatory activities. The EO obtained from N. cataria var. citriodora grown in Serbia shows valuable biological activity, indicating its potential for use as a supplement in everyday diet and as a natural preservative in food industry.
PB  - Lublin : Uniwersytetu  Przyrodniczego Lublin
T2  - Acta Scientiarum Polonorum Hortorum Cultus
T1  - Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities
VL  - 21
IS  - 4
SP  - 67
EP  - 74
DO  - 10.24326/asphc.2022.4.7
ER  - 
@article{
author = "Aćimović, Milica and Šeregelj, Vanja and Simić, Katarina and Varga, Ana and Pezo, Lato and Vulić, Jelena and Čabarkapa, Ivana",
year = "2022",
abstract = "Essential oil (EO) obtained by hydrodistillation in a Clevenger-type apparatus from aerial parts of Nepeta cataria L. var. citriodora (Becker), cultivated in Serbia was subjected to gas chromatography-mass spectroscopy (GC-MS) to determine the composition. Furthermore, N. cataria var. citriodora essential oil was
tested to determine its antimicrobial, antioxidant, antihyperglycemic and anti-inflammatory activities in vitro.
The antimicrobial activity was tested by broth microdilution method against 16 bacterial strains from American Type Culture Collection (ATCC). Four common tests for measuring in vitro antioxidant activity were used: 2, 2-diphenyl-1-picrylhydrazyl assay (DPPH), reducing power (RP), 2,2-azino-bis-3-ethylbenzothiazoline-
6-sulfonic acid (ABTS) and β-carotene bleaching assay (BCB). Antihyperglycemic activity was examined by using α-glucosidase inhibitory potential (AHgA), while anti-inflammatory activity (AIA) was determined by protein denaturation bioassay, using egg albumin. In total, 36 compounds were isolated and detected by GC-MS technique in N. cataria var. citriodora EO. The EO is mainly comprised of oxygenated monoterpenes (93.1%), and the main compounds were two monoterpenoid alcohols, nerol (38.5%) and geraniol (24.9%), followed by two aliphatic aldehyde, geranial (14.6%) and neral (11.0%). Antimicrobial activity of this EO shows growth inhibition of all tested bacteria strains, and exhibited good antioxidant, antihyperglycemic and anti-inflammatory activities. The EO obtained from N. cataria var. citriodora grown in Serbia shows valuable biological activity, indicating its potential for use as a supplement in everyday diet and as a natural preservative in food industry.",
publisher = "Lublin : Uniwersytetu  Przyrodniczego Lublin",
journal = "Acta Scientiarum Polonorum Hortorum Cultus",
title = "Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities",
volume = "21",
number = "4",
pages = "67-74",
doi = "10.24326/asphc.2022.4.7"
}
Aćimović, M., Šeregelj, V., Simić, K., Varga, A., Pezo, L., Vulić, J.,& Čabarkapa, I.. (2022). Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities. in Acta Scientiarum Polonorum Hortorum Cultus
Lublin : Uniwersytetu  Przyrodniczego Lublin., 21(4), 67-74.
https://doi.org/10.24326/asphc.2022.4.7
Aćimović M, Šeregelj V, Simić K, Varga A, Pezo L, Vulić J, Čabarkapa I. Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities. in Acta Scientiarum Polonorum Hortorum Cultus. 2022;21(4):67-74.
doi:10.24326/asphc.2022.4.7 .
Aćimović, Milica, Šeregelj, Vanja, Simić, Katarina, Varga, Ana, Pezo, Lato, Vulić, Jelena, Čabarkapa, Ivana, "Chemical profile of Nepeta cataria L. var. citriodora (Becker) essential oil and in vitro evaluation of biological activities" in Acta Scientiarum Polonorum Hortorum Cultus, 21, no. 4 (2022):67-74,
https://doi.org/10.24326/asphc.2022.4.7 . .
3
1

Volatile Profile of Garden Rose (Rosa hybrida) Hydrosol and Evaluation of Its Biological Activity In Vitro

Božanić Tanjga, Biljana; Lončar, Biljana; Aćimović, Milica; Kiprovski, Biljana; Šovljanski, Olja; Tomić, Ana; Travičić, Vanja; Cvetković, Mirjana; Raičević, Vidak; Zeremski, Tijana

(Switzerland : Multidisciplinary Digital Publishing Institute (MDPI), 2022)

TY  - JOUR
AU  - Božanić Tanjga, Biljana
AU  - Lončar, Biljana
AU  - Aćimović, Milica
AU  - Kiprovski, Biljana
AU  - Šovljanski, Olja
AU  - Tomić, Ana
AU  - Travičić, Vanja
AU  - Cvetković, Mirjana
AU  - Raičević, Vidak
AU  - Zeremski, Tijana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5364
AB  - Garden rose, Rosa hybrida, is primarily used for decoration and has a wide range of growing
area, contrary to R. damascena that has a limited area of distribution (Turkey and Bulgaria), yet it is
extensively used for commercial production of valuable and expensive rose oil. Since the content of
essential oil in rose petals is low (0.03–0.04%), its production is quite limited; however, during this
process, a significant amount of rose hydrosol is obtained as a secondary product. The aim of this
research was to determine the chemical composition of garden rose hydrosols and to evaluate their
biological properties. Obtained results show that R. hybrida hydrosol containing phenylethyl alcohol,
nerol, linalool, and geraniol may be used as an alternative for R. damascena hydrosol. However, the
total phenolic content was quite low (4.96 _g GAE/mL), which is related to a low level of observed
antioxidant activity based on different antioxidant activity assays. Furthermore, R. hybrida hydrosol
did not exhibit antimicrobial activity against several gram-positive and gram-negative bacteria, as
well as yeast and fungi. Anti-inflammatory activity was also low, while no antihyperglycemic activity
was detected. With these results in mind, no potential is evident for the therapeutic application of
rose hydrosol beyond that found in complimentary medicine such as aromatherapy.
PB  - Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)
T2  - Horticulturae
T1  - Volatile Profile of Garden Rose (Rosa hybrida) Hydrosol and Evaluation of Its Biological Activity In Vitro
VL  - 8
IS  - 10
SP  - 895
DO  - 10.3390/horticulturae8100895
ER  - 
@article{
author = "Božanić Tanjga, Biljana and Lončar, Biljana and Aćimović, Milica and Kiprovski, Biljana and Šovljanski, Olja and Tomić, Ana and Travičić, Vanja and Cvetković, Mirjana and Raičević, Vidak and Zeremski, Tijana",
year = "2022",
abstract = "Garden rose, Rosa hybrida, is primarily used for decoration and has a wide range of growing
area, contrary to R. damascena that has a limited area of distribution (Turkey and Bulgaria), yet it is
extensively used for commercial production of valuable and expensive rose oil. Since the content of
essential oil in rose petals is low (0.03–0.04%), its production is quite limited; however, during this
process, a significant amount of rose hydrosol is obtained as a secondary product. The aim of this
research was to determine the chemical composition of garden rose hydrosols and to evaluate their
biological properties. Obtained results show that R. hybrida hydrosol containing phenylethyl alcohol,
nerol, linalool, and geraniol may be used as an alternative for R. damascena hydrosol. However, the
total phenolic content was quite low (4.96 _g GAE/mL), which is related to a low level of observed
antioxidant activity based on different antioxidant activity assays. Furthermore, R. hybrida hydrosol
did not exhibit antimicrobial activity against several gram-positive and gram-negative bacteria, as
well as yeast and fungi. Anti-inflammatory activity was also low, while no antihyperglycemic activity
was detected. With these results in mind, no potential is evident for the therapeutic application of
rose hydrosol beyond that found in complimentary medicine such as aromatherapy.",
publisher = "Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)",
journal = "Horticulturae",
title = "Volatile Profile of Garden Rose (Rosa hybrida) Hydrosol and Evaluation of Its Biological Activity In Vitro",
volume = "8",
number = "10",
pages = "895",
doi = "10.3390/horticulturae8100895"
}
Božanić Tanjga, B., Lončar, B., Aćimović, M., Kiprovski, B., Šovljanski, O., Tomić, A., Travičić, V., Cvetković, M., Raičević, V.,& Zeremski, T.. (2022). Volatile Profile of Garden Rose (Rosa hybrida) Hydrosol and Evaluation of Its Biological Activity In Vitro. in Horticulturae
Switzerland : Multidisciplinary Digital Publishing Institute (MDPI)., 8(10), 895.
https://doi.org/10.3390/horticulturae8100895
Božanić Tanjga B, Lončar B, Aćimović M, Kiprovski B, Šovljanski O, Tomić A, Travičić V, Cvetković M, Raičević V, Zeremski T. Volatile Profile of Garden Rose (Rosa hybrida) Hydrosol and Evaluation of Its Biological Activity In Vitro. in Horticulturae. 2022;8(10):895.
doi:10.3390/horticulturae8100895 .
Božanić Tanjga, Biljana, Lončar, Biljana, Aćimović, Milica, Kiprovski, Biljana, Šovljanski, Olja, Tomić, Ana, Travičić, Vanja, Cvetković, Mirjana, Raičević, Vidak, Zeremski, Tijana, "Volatile Profile of Garden Rose (Rosa hybrida) Hydrosol and Evaluation of Its Biological Activity In Vitro" in Horticulturae, 8, no. 10 (2022):895,
https://doi.org/10.3390/horticulturae8100895 . .
2
9

Chamomile essential oil quality after postharvest separation treatments

Aćimović, Milica; Lončar, Biljana; Kiprovski, Biljana; Stanković Jeremić, Jovana; Todosijević, Marina; Pezo, Lato; Jeremić, Jelena

(Novi Sad : Institut za ratarstvo i povrtarstvo, 2021)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Lončar, Biljana
AU  - Kiprovski, Biljana
AU  - Stanković Jeremić, Jovana
AU  - Todosijević, Marina
AU  - Pezo, Lato
AU  - Jeremić, Jelena
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4785
AB  - Ecological conditions of the growing areas, growing practices as well as harvest and postharvest processing influence the yield and quality of chamomile. The aim of this research was to determine the influence of chamomile separation methods, as postharvest treatments, on the essential oil quality and content, with a view to improve current primary processing of this valuable medicinal plant. In order to explain the structure of laboratory data that would give deeper assessment of similarities among various samples of chamomile essential oil, PCA was employed. Tested results showed that separation of chamomile plant material, as postharvest and pre-drying treatment, had significant influence on the number of identified compounds in the chamomile essential oil. The highest content of individual essential oil compounds had chamomile flowers with short stems, especially α-bisabolol, chamazulene, Z-spiroether and E-β-farnesene. In the essential oil obtained from chamomile flowers with long stems, content of α-bisabolol and chamazulene were significantly lower, while E-β-farnesene and Z-spiroether contents were significantly higher. Furthermore, in the essential oil obtained from chamomile plant material without separation, the lowest content of αbisabolol and Z-spiroether, and the highest content of E-β-farnesene were recorded. The correlation analysis was performed to investigate the likeness in the amounts of the active compounds of essential oil from differently processed chamomile samples. All these results indicate the importance of precise and controlled postharvest treatments, since it clearly affects the essential oil quality and content in the primary processing of this valuable medicinal plant.
AB  - Ekološki uslovi proizvodnog područja, tehnologija gajenja kao i žetva, ali i posležetveni tretmani značajno utiču na prinos i kvalitet kamilice. Cilj ovog istraživanja je bio da se odredi uticaj metoda separacije, kao posležetvenog tretmana, na kvalitet etarskog ulja, sa ciljem da se unapredi process primarne prerade ove lekovite biljke. Da bi se objasnila struktura laboratorijskih podataka, procenile i sagledale sličnosti i razlike između uzoraka etarskih ulja kamilice dobijenih primenom različitih metoda separacije, korišćena je PCA metoda. Dobijeni rezultati pokazuju da separacija sirovine kamilice kao posležetveni tretman koji prethodi sušenju, ima značajnog uticaja na broj identifikovanih komponenti u etarskom ulju, ali i njihov udeo. Najmanji broj pojedinačnih komponenti u etarskom ulju je imao uzorak cvetnih glavica sa kratkom drškom, pri čemu je zabeležen najveći sadržaj α-bisabolol, hamazulen, Z-spiroeter i E-β-farnesen. U etarskom ulju dobijenom od biljne sirovine sa većim udelom stabla kamilice, sadržaj α-bisabolola i hamazulena je bio značajno niži, dok je sadržaj E-β-farnesena i Z-spiroetera bio značajno viši. Dalje, u etarskom ulju dobijenom od bioljnog materijala bez separacije, zabeležen je najniži sadržaj α-bisabolola i Z-spiroetera, i najveći sadržaj E-β-farnesena. Analiza korelacije je izvedena da bi se ispitala sličnost u sadržaju aktivnih komponenti u etarskom ulju dobijenom primenom različitih procesa separacije kamilice. Svi rezultati ukazuju na značaj primene posležetvenih tretmana, jer se jasno vidi njihov uticaj na kvalitet etarskog ulja ove veoma važne lekovite biljke.
PB  - Novi Sad : Institut za ratarstvo i povrtarstvo
T2  - Ratarstvo i Povrtarstvo
T1  - Chamomile essential oil quality after postharvest separation treatments
T1  - Uticaj tretmana poslezetvene separacije na kvalitet etarskog ulja kamilice
VL  - 58
VL  - 2
SP  - 72
EP  - 78
DO  - 10.5937/RATPOV58-33346
ER  - 
@article{
author = "Aćimović, Milica and Lončar, Biljana and Kiprovski, Biljana and Stanković Jeremić, Jovana and Todosijević, Marina and Pezo, Lato and Jeremić, Jelena",
year = "2021",
abstract = "Ecological conditions of the growing areas, growing practices as well as harvest and postharvest processing influence the yield and quality of chamomile. The aim of this research was to determine the influence of chamomile separation methods, as postharvest treatments, on the essential oil quality and content, with a view to improve current primary processing of this valuable medicinal plant. In order to explain the structure of laboratory data that would give deeper assessment of similarities among various samples of chamomile essential oil, PCA was employed. Tested results showed that separation of chamomile plant material, as postharvest and pre-drying treatment, had significant influence on the number of identified compounds in the chamomile essential oil. The highest content of individual essential oil compounds had chamomile flowers with short stems, especially α-bisabolol, chamazulene, Z-spiroether and E-β-farnesene. In the essential oil obtained from chamomile flowers with long stems, content of α-bisabolol and chamazulene were significantly lower, while E-β-farnesene and Z-spiroether contents were significantly higher. Furthermore, in the essential oil obtained from chamomile plant material without separation, the lowest content of αbisabolol and Z-spiroether, and the highest content of E-β-farnesene were recorded. The correlation analysis was performed to investigate the likeness in the amounts of the active compounds of essential oil from differently processed chamomile samples. All these results indicate the importance of precise and controlled postharvest treatments, since it clearly affects the essential oil quality and content in the primary processing of this valuable medicinal plant., Ekološki uslovi proizvodnog područja, tehnologija gajenja kao i žetva, ali i posležetveni tretmani značajno utiču na prinos i kvalitet kamilice. Cilj ovog istraživanja je bio da se odredi uticaj metoda separacije, kao posležetvenog tretmana, na kvalitet etarskog ulja, sa ciljem da se unapredi process primarne prerade ove lekovite biljke. Da bi se objasnila struktura laboratorijskih podataka, procenile i sagledale sličnosti i razlike između uzoraka etarskih ulja kamilice dobijenih primenom različitih metoda separacije, korišćena je PCA metoda. Dobijeni rezultati pokazuju da separacija sirovine kamilice kao posležetveni tretman koji prethodi sušenju, ima značajnog uticaja na broj identifikovanih komponenti u etarskom ulju, ali i njihov udeo. Najmanji broj pojedinačnih komponenti u etarskom ulju je imao uzorak cvetnih glavica sa kratkom drškom, pri čemu je zabeležen najveći sadržaj α-bisabolol, hamazulen, Z-spiroeter i E-β-farnesen. U etarskom ulju dobijenom od biljne sirovine sa većim udelom stabla kamilice, sadržaj α-bisabolola i hamazulena je bio značajno niži, dok je sadržaj E-β-farnesena i Z-spiroetera bio značajno viši. Dalje, u etarskom ulju dobijenom od bioljnog materijala bez separacije, zabeležen je najniži sadržaj α-bisabolola i Z-spiroetera, i najveći sadržaj E-β-farnesena. Analiza korelacije je izvedena da bi se ispitala sličnost u sadržaju aktivnih komponenti u etarskom ulju dobijenom primenom različitih procesa separacije kamilice. Svi rezultati ukazuju na značaj primene posležetvenih tretmana, jer se jasno vidi njihov uticaj na kvalitet etarskog ulja ove veoma važne lekovite biljke.",
publisher = "Novi Sad : Institut za ratarstvo i povrtarstvo",
journal = "Ratarstvo i Povrtarstvo",
title = "Chamomile essential oil quality after postharvest separation treatments, Uticaj tretmana poslezetvene separacije na kvalitet etarskog ulja kamilice",
volume = "58, 2",
pages = "72-78",
doi = "10.5937/RATPOV58-33346"
}
Aćimović, M., Lončar, B., Kiprovski, B., Stanković Jeremić, J., Todosijević, M., Pezo, L.,& Jeremić, J.. (2021). Chamomile essential oil quality after postharvest separation treatments. in Ratarstvo i Povrtarstvo
Novi Sad : Institut za ratarstvo i povrtarstvo., 58, 72-78.
https://doi.org/10.5937/RATPOV58-33346
Aćimović M, Lončar B, Kiprovski B, Stanković Jeremić J, Todosijević M, Pezo L, Jeremić J. Chamomile essential oil quality after postharvest separation treatments. in Ratarstvo i Povrtarstvo. 2021;58:72-78.
doi:10.5937/RATPOV58-33346 .
Aćimović, Milica, Lončar, Biljana, Kiprovski, Biljana, Stanković Jeremić, Jovana, Todosijević, Marina, Pezo, Lato, Jeremić, Jelena, "Chamomile essential oil quality after postharvest separation treatments" in Ratarstvo i Povrtarstvo, 58 (2021):72-78,
https://doi.org/10.5937/RATPOV58-33346 . .
3
3

Weather conditions influence on hyssop essential oil quality

Aćimović, Milica; Pezo, Lato; Zeremski, Tijana; Lončar, Biljana; Marjanović Jeromela, Ana; Stanković Jeremić, Jovana; Cvetković, Mirjana; Sikora, Vladimir; Ignjatov, Maja

(MDPI, 2021)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Zeremski, Tijana
AU  - Lončar, Biljana
AU  - Marjanović  Jeromela, Ana
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
AU  - Sikora, Vladimir
AU  - Ignjatov, Maja
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4829
AB  - This paper is a study of the chemical composition of Hyssopus officinalis ssp. Officinalis grown during three years (2017-2019) at the Institute of Field and Vegetable Crops Novi Sad (Vojvodina Province, Serbia). Furthermore, comparisons with ISO standards during the years were also investigated, as well as a prediction model of retention indices of compounds from the essential oils. An essential oil obtained by hydrodistillation and analysed by GC-FID and GC-MS was isopinocamphone chemotype. The gathered information about the volatile compounds from H. officinalis was used to classify the samples using the unrooted cluster tree. The correlation analysis was applied to investigate the similarity of different samples, according to GC-MS data. The quantitative structure- retention relationship (QSRR) was also employed to predict the retention indices of the identified compounds. A total of 74 experimentally obtained retention indices were used to build a prediction model. The coefficient of determination for the training cycle was 0.910, indicating that this model could be used for the prediction of retention indices for H. officinalis essential oil compounds.
PB  - MDPI
T2  - Processes
T1  - Weather conditions influence on hyssop essential oil quality
VL  - 9
IS  - 7
SP  - 1152
DO  - 10.3390/pr9071152
ER  - 
@article{
author = "Aćimović, Milica and Pezo, Lato and Zeremski, Tijana and Lončar, Biljana and Marjanović  Jeromela, Ana and Stanković Jeremić, Jovana and Cvetković, Mirjana and Sikora, Vladimir and Ignjatov, Maja",
year = "2021",
abstract = "This paper is a study of the chemical composition of Hyssopus officinalis ssp. Officinalis grown during three years (2017-2019) at the Institute of Field and Vegetable Crops Novi Sad (Vojvodina Province, Serbia). Furthermore, comparisons with ISO standards during the years were also investigated, as well as a prediction model of retention indices of compounds from the essential oils. An essential oil obtained by hydrodistillation and analysed by GC-FID and GC-MS was isopinocamphone chemotype. The gathered information about the volatile compounds from H. officinalis was used to classify the samples using the unrooted cluster tree. The correlation analysis was applied to investigate the similarity of different samples, according to GC-MS data. The quantitative structure- retention relationship (QSRR) was also employed to predict the retention indices of the identified compounds. A total of 74 experimentally obtained retention indices were used to build a prediction model. The coefficient of determination for the training cycle was 0.910, indicating that this model could be used for the prediction of retention indices for H. officinalis essential oil compounds.",
publisher = "MDPI",
journal = "Processes",
title = "Weather conditions influence on hyssop essential oil quality",
volume = "9",
number = "7",
pages = "1152",
doi = "10.3390/pr9071152"
}
Aćimović, M., Pezo, L., Zeremski, T., Lončar, B., Marjanović  Jeromela, A., Stanković Jeremić, J., Cvetković, M., Sikora, V.,& Ignjatov, M.. (2021). Weather conditions influence on hyssop essential oil quality. in Processes
MDPI., 9(7), 1152.
https://doi.org/10.3390/pr9071152
Aćimović M, Pezo L, Zeremski T, Lončar B, Marjanović  Jeromela A, Stanković Jeremić J, Cvetković M, Sikora V, Ignjatov M. Weather conditions influence on hyssop essential oil quality. in Processes. 2021;9(7):1152.
doi:10.3390/pr9071152 .
Aćimović, Milica, Pezo, Lato, Zeremski, Tijana, Lončar, Biljana, Marjanović  Jeromela, Ana, Stanković Jeremić, Jovana, Cvetković, Mirjana, Sikora, Vladimir, Ignjatov, Maja, "Weather conditions influence on hyssop essential oil quality" in Processes, 9, no. 7 (2021):1152,
https://doi.org/10.3390/pr9071152 . .
8
16
2
14

Essential oil quality of chamomile grown in Province of Vojvodina

Aćimović, Milica; Stanković Jeremić, Jovana; Simić, Katarina; Ivanović, Stefan; Ljujić, Jovana; Čabarkapa, Ivana; Radojčin, Milivoj; Todosijević, Marina; Cvetković, Mirjana

(Novi Sad: Poljoprivredni fakultet, 2021)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Stanković Jeremić, Jovana
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Ljujić, Jovana
AU  - Čabarkapa, Ivana
AU  - Radojčin, Milivoj
AU  - Todosijević, Marina
AU  - Cvetković, Mirjana
PY  - 2021
UR  - http://letopisnaucnihradova.rs/wp-content/uploads/2021/09/Essential_oil_quality_of_chamomile_grown_in_Province_of_Vojvodina-Acimovic_et_al..pdf
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5167
AB  - Chamomile (Matricaria chamomilla L., Asteraceae) is one of the most popular medicinal plants used as a herb
infusion for treating numerous ailments, including sleep disorders, anxiety, digestion and intestinal conditions
etc. Chamomile essential oil is used in a wide variety of consumer goods such as detergents, soaps, toiletries,
cosmetics, pharmaceuticals, perfumes, confectionery food products, soft drinks, distilled alcoholic beverages
(hard liquor) and as insecticide. According to the European Pharmacopoeia, there are two types of essential
oils, one rich in bisabolol oxides and the other in α-bisabolol, which are preferred for tea brewing because of
its sweet, grassy, and slightly fruity aroma. From the other side, varieties rich in chamazulene and β-farnesene
have bitter taste, and because of that they are low valuable raw material. According to the results of the
essential oil composition obtained from three different chamomile samples grown in Province of Vojvodina, it
could be concluded that domestic cultivars “Banatska” and “Tetraploidna” contains β-farnesene as dominant
compound, while the content of bisabolol oxides and α-bisabolol was lower than required standards in
European Pharmacopoeia. Because of that they could not be classified as quality raw material. The German
cultivar “Mabamille” grown in agroecological conditions of Vojvodina region, with 37.5% of α-bisabolol can be
classified as a bisabolol rich type, and as high quality row material.
AB  - Kamilica (Matricaria chamomilla L., Asteraceae) je jedna od najpopularnijih lekovitih biljaka koja se 
upotrebljava u obliku infuza (čaja) za lečenje mnogih stanja i bolesti, uključujući poremećaje sna, napetost, probleme organa za varenje itd. Etarsko ulje kamilice se koristi u mnogim granama industrije: hemijskoj (kao dodatak deterdžentima), kozmetičkoj (u sapunima, sredstvima za ličnu higijenu), farmaceutskoj, parfimerijskoj i prehrambenoj industriji (u slatkišima, alkoholnim i bezalkoholnim pićima) i kao insekticid. Prema Evropskoj Farmakopeji, postoje dva tipa etarskog ulja kamilice, prvi koji je bogat bisabolol oksidima i drugi bogat α-bisabololom. Oba tipa su poželjna u industriji čajnih napitaka zbog njihovog slatkog, osvežavajućeg ukusa blago voćne arome. Sa druge strane, varijeteti bogati hamazulenom i β-farnezenom imaju gorak ukus i zbog toga predstavljaju manje vrednu biljnu sirovinu. Na osnovu rezultata hemijskog sastava etarskog ulja tri 
različita uzorka kamilice gajene u Pokrajini Vojvodini od strane individualnih poljoprivrednih proizvođača, može se zaključiti da domaće sorte “Banatska” i “Tetraploidna” sadrže β-farnezen kao dominantnu komponentu, dok je sadržaj bisabolol oksida i α-bisabolola niži nego što zahtevaju standardi u Evropskoj Farmakopeji, zbog čega se ne mogu kategorisati kao kvalitetni biljni materijal. Nemačka sorta “Mabamille” gajena u agroekološkim uslovima pokrajine Vojvodine, sa 37,5% α-bisabolola pripada bisabolol tipu kamilice i predstavlja visoko kvalitetnu sirovinu.
PB  - Novi Sad: Poljoprivredni fakultet
T2  - Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad
T1  - Essential oil quality of chamomile grown in Province of Vojvodina
VL  - 45
IS  - 1
SP  - 1
EP  - 8
UR  - https://hdl.handle.net/21.15107/rcub_cer_5167
ER  - 
@article{
author = "Aćimović, Milica and Stanković Jeremić, Jovana and Simić, Katarina and Ivanović, Stefan and Ljujić, Jovana and Čabarkapa, Ivana and Radojčin, Milivoj and Todosijević, Marina and Cvetković, Mirjana",
year = "2021",
abstract = "Chamomile (Matricaria chamomilla L., Asteraceae) is one of the most popular medicinal plants used as a herb
infusion for treating numerous ailments, including sleep disorders, anxiety, digestion and intestinal conditions
etc. Chamomile essential oil is used in a wide variety of consumer goods such as detergents, soaps, toiletries,
cosmetics, pharmaceuticals, perfumes, confectionery food products, soft drinks, distilled alcoholic beverages
(hard liquor) and as insecticide. According to the European Pharmacopoeia, there are two types of essential
oils, one rich in bisabolol oxides and the other in α-bisabolol, which are preferred for tea brewing because of
its sweet, grassy, and slightly fruity aroma. From the other side, varieties rich in chamazulene and β-farnesene
have bitter taste, and because of that they are low valuable raw material. According to the results of the
essential oil composition obtained from three different chamomile samples grown in Province of Vojvodina, it
could be concluded that domestic cultivars “Banatska” and “Tetraploidna” contains β-farnesene as dominant
compound, while the content of bisabolol oxides and α-bisabolol was lower than required standards in
European Pharmacopoeia. Because of that they could not be classified as quality raw material. The German
cultivar “Mabamille” grown in agroecological conditions of Vojvodina region, with 37.5% of α-bisabolol can be
classified as a bisabolol rich type, and as high quality row material., Kamilica (Matricaria chamomilla L., Asteraceae) je jedna od najpopularnijih lekovitih biljaka koja se 
upotrebljava u obliku infuza (čaja) za lečenje mnogih stanja i bolesti, uključujući poremećaje sna, napetost, probleme organa za varenje itd. Etarsko ulje kamilice se koristi u mnogim granama industrije: hemijskoj (kao dodatak deterdžentima), kozmetičkoj (u sapunima, sredstvima za ličnu higijenu), farmaceutskoj, parfimerijskoj i prehrambenoj industriji (u slatkišima, alkoholnim i bezalkoholnim pićima) i kao insekticid. Prema Evropskoj Farmakopeji, postoje dva tipa etarskog ulja kamilice, prvi koji je bogat bisabolol oksidima i drugi bogat α-bisabololom. Oba tipa su poželjna u industriji čajnih napitaka zbog njihovog slatkog, osvežavajućeg ukusa blago voćne arome. Sa druge strane, varijeteti bogati hamazulenom i β-farnezenom imaju gorak ukus i zbog toga predstavljaju manje vrednu biljnu sirovinu. Na osnovu rezultata hemijskog sastava etarskog ulja tri 
različita uzorka kamilice gajene u Pokrajini Vojvodini od strane individualnih poljoprivrednih proizvođača, može se zaključiti da domaće sorte “Banatska” i “Tetraploidna” sadrže β-farnezen kao dominantnu komponentu, dok je sadržaj bisabolol oksida i α-bisabolola niži nego što zahtevaju standardi u Evropskoj Farmakopeji, zbog čega se ne mogu kategorisati kao kvalitetni biljni materijal. Nemačka sorta “Mabamille” gajena u agroekološkim uslovima pokrajine Vojvodine, sa 37,5% α-bisabolola pripada bisabolol tipu kamilice i predstavlja visoko kvalitetnu sirovinu.",
publisher = "Novi Sad: Poljoprivredni fakultet",
journal = "Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad",
title = "Essential oil quality of chamomile grown in Province of Vojvodina",
volume = "45",
number = "1",
pages = "1-8",
url = "https://hdl.handle.net/21.15107/rcub_cer_5167"
}
Aćimović, M., Stanković Jeremić, J., Simić, K., Ivanović, S., Ljujić, J., Čabarkapa, I., Radojčin, M., Todosijević, M.,& Cvetković, M.. (2021). Essential oil quality of chamomile grown in Province of Vojvodina. in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad
Novi Sad: Poljoprivredni fakultet., 45(1), 1-8.
https://hdl.handle.net/21.15107/rcub_cer_5167
Aćimović M, Stanković Jeremić J, Simić K, Ivanović S, Ljujić J, Čabarkapa I, Radojčin M, Todosijević M, Cvetković M. Essential oil quality of chamomile grown in Province of Vojvodina. in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad. 2021;45(1):1-8.
https://hdl.handle.net/21.15107/rcub_cer_5167 .
Aćimović, Milica, Stanković Jeremić, Jovana, Simić, Katarina, Ivanović, Stefan, Ljujić, Jovana, Čabarkapa, Ivana, Radojčin, Milivoj, Todosijević, Marina, Cvetković, Mirjana, "Essential oil quality of chamomile grown in Province of Vojvodina" in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad, 45, no. 1 (2021):1-8,
https://hdl.handle.net/21.15107/rcub_cer_5167 .

The quantitative structure retention relationship of the gs ms profile of yarrow essential oil

Aćimović, Milica; Pezo, Lato; Stanković Jeremić, Jovana; Todosijević, Marina; Rat, Milica; Tešević, Vele; Cvetković, Mirjana

(Novi Sad : Faculty of Technology, 2021)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Stanković Jeremić, Jovana
AU  - Todosijević, Marina
AU  - Rat, Milica
AU  - Tešević, Vele
AU  - Cvetković, Mirjana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5291
AB  - In the essential oil of yarrow (Achillea millefolium L. sensu lato) collected from natural popula-
tion on Mt. Rtanj (Serbia) and distilled by Clevenger apparatus 104 compounds were detected, and

the most abundant were camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-

cineole (5.6%). The quantitative structure-retention relationship (QSRR) model was employed to pre-
dict the retention indices, using four molecular descriptors selected by factor analysis and a genetic

algorithm. The coefficients of determination reached the value of 0.862, demonstrating that this mo-
del could be used for prediction purposes.
PB  - Novi Sad : Faculty of Technology
T2  - Acta Periodica Technologica
T1  - The quantitative structure retention relationship of the gs ms profile of yarrow essential oil
IS  - 52
SP  - 123
EP  - 132
DO  - 10.2298/APT2152123A
ER  - 
@article{
author = "Aćimović, Milica and Pezo, Lato and Stanković Jeremić, Jovana and Todosijević, Marina and Rat, Milica and Tešević, Vele and Cvetković, Mirjana",
year = "2021",
abstract = "In the essential oil of yarrow (Achillea millefolium L. sensu lato) collected from natural popula-
tion on Mt. Rtanj (Serbia) and distilled by Clevenger apparatus 104 compounds were detected, and

the most abundant were camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-

cineole (5.6%). The quantitative structure-retention relationship (QSRR) model was employed to pre-
dict the retention indices, using four molecular descriptors selected by factor analysis and a genetic

algorithm. The coefficients of determination reached the value of 0.862, demonstrating that this mo-
del could be used for prediction purposes.",
publisher = "Novi Sad : Faculty of Technology",
journal = "Acta Periodica Technologica",
title = "The quantitative structure retention relationship of the gs ms profile of yarrow essential oil",
number = "52",
pages = "123-132",
doi = "10.2298/APT2152123A"
}
Aćimović, M., Pezo, L., Stanković Jeremić, J., Todosijević, M., Rat, M., Tešević, V.,& Cvetković, M.. (2021). The quantitative structure retention relationship of the gs ms profile of yarrow essential oil. in Acta Periodica Technologica
Novi Sad : Faculty of Technology.(52), 123-132.
https://doi.org/10.2298/APT2152123A
Aćimović M, Pezo L, Stanković Jeremić J, Todosijević M, Rat M, Tešević V, Cvetković M. The quantitative structure retention relationship of the gs ms profile of yarrow essential oil. in Acta Periodica Technologica. 2021;(52):123-132.
doi:10.2298/APT2152123A .
Aćimović, Milica, Pezo, Lato, Stanković Jeremić, Jovana, Todosijević, Marina, Rat, Milica, Tešević, Vele, Cvetković, Mirjana, "The quantitative structure retention relationship of the gs ms profile of yarrow essential oil" in Acta Periodica Technologica, no. 52 (2021):123-132,
https://doi.org/10.2298/APT2152123A . .
1
1

Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity

Aćimović, Milica; Varga, Ana; Cvetković, Mirjana; Lato, Pezo; Lončar, Biljana; Ignjatov, Maja; Zeremski, Tijana

(Belgrade : Centre for Evaluation in Education and Science, 2021)

TY  - JOUR
AU  - Aćimović, Milica
AU  - Varga, Ana
AU  - Cvetković, Mirjana
AU  - Lato, Pezo
AU  - Lončar, Biljana
AU  - Ignjatov, Maja
AU  - Zeremski, Tijana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4692
AB  - Hyssop (Hyssopus officinalis L., Lamiaceae) is a perennial shrub or subshrub violet-blue flowers in verticillasters and spicy taste with a pungent flavour. Besides being used as a culinary herb for flavouring and food preservation, this plant is also an ornamental, bee attracting plant and a traditional remedy for respiratory diseases and digestive disturbances. Hyssop is an essential oil-bearing plant, and its essential oil (Hyssopi aetheroleum) is used in the pharmaceutical, perfume and cosmetics industries as well as in aromatherapy. The objective of this study was to determine the chemical composition of essential oil of hyssop CV. "Domaći ljubičasti", grown in Serbia, and investigate its antimicrobial activity against 16 bacteria, mainly pathogens in the food industry. A total of 61 compounds were detected in the hyssop essential oil. The bicyclic monoterpene ketones CIS-pinocamphone (43.8%) and trans-pinocamphone (18.3%) were the most abundant, comprising 62.1%, followed by b-pinene (6.3%) and pinocarvone (6.1%). Hyssop essential oil expressed antibacterial activity against: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua and Bacillus spizizenii. Hyssop essential oil did not express antibacterial activity against Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes and Staphylococcus epidermidis. Results of this study show that hyssop essential oil has potential for using as natural supplement for control of foodborne diseases of microbiological origin, as well as flavor compositions (herbaceous, camphor-like odour with warm and spicy undernotes), especially for meat products, sauces, soups and seasonings.
AB  - Miloduh (Hyssopus officinalis L., Lamiaceae) je višegodišnji žbun ili polužbun aromatičnog i oštrog mirisa zbog čega se koristi kao začinska biljka. Takođe je i ukrasna i medonosna biljka, ali i tradicionalni lek za bolesti organa za disanje i kod poremećaja varenja. Miloduh je cenjena eterično-aromatična biljka, a etarsko ulje se koristi u farmaceutskoj, parfimerijskoj i kozmetičkoj industriji kao i aromaterapiji. Cilj ovog istraživanja je bio da se determiniše hemijski sastav etarskog ulja miloduha kultivara „Domaći ljubičasti“ gajenog u Srbiji, i da se ispita antimikrobna aktivnost na 16 bakterija, uglavnom patogena u prehrambenoj industriji. Ukupno 61 komponenta je detektovana u etarskom ulju, pri čemu su monoterpenski ketoni cis-pinokamfon (43.8%) i trans-pinokamfon (18.3%) bili najzastupljeniji, čineći 62.1%, a potom slede β-pinen i pinokarvon. Etarsko ulje miloduha je ispoljilo antibakterijsku aktivnost na: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua i Bacillus spizizenii, dok nije delovalo na Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes i Staphylococcus epidermidis.
PB  - Belgrade : Centre for Evaluation in Education and Science
T2  - Ratarstvo i Povrtarstvo
T1  - Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity
T1  - Hemijski sastav etarskog ulja miloduha kultivara  'Domaći ljubičasti' i ocena antimikrobne aktivnosti
VL  - 58
IS  - 1
SP  - 23
EP  - 30
DO  - 10.5937/ratpov58-31751
ER  - 
@article{
author = "Aćimović, Milica and Varga, Ana and Cvetković, Mirjana and Lato, Pezo and Lončar, Biljana and Ignjatov, Maja and Zeremski, Tijana",
year = "2021",
abstract = "Hyssop (Hyssopus officinalis L., Lamiaceae) is a perennial shrub or subshrub violet-blue flowers in verticillasters and spicy taste with a pungent flavour. Besides being used as a culinary herb for flavouring and food preservation, this plant is also an ornamental, bee attracting plant and a traditional remedy for respiratory diseases and digestive disturbances. Hyssop is an essential oil-bearing plant, and its essential oil (Hyssopi aetheroleum) is used in the pharmaceutical, perfume and cosmetics industries as well as in aromatherapy. The objective of this study was to determine the chemical composition of essential oil of hyssop CV. "Domaći ljubičasti", grown in Serbia, and investigate its antimicrobial activity against 16 bacteria, mainly pathogens in the food industry. A total of 61 compounds were detected in the hyssop essential oil. The bicyclic monoterpene ketones CIS-pinocamphone (43.8%) and trans-pinocamphone (18.3%) were the most abundant, comprising 62.1%, followed by b-pinene (6.3%) and pinocarvone (6.1%). Hyssop essential oil expressed antibacterial activity against: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua and Bacillus spizizenii. Hyssop essential oil did not express antibacterial activity against Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes and Staphylococcus epidermidis. Results of this study show that hyssop essential oil has potential for using as natural supplement for control of foodborne diseases of microbiological origin, as well as flavor compositions (herbaceous, camphor-like odour with warm and spicy undernotes), especially for meat products, sauces, soups and seasonings., Miloduh (Hyssopus officinalis L., Lamiaceae) je višegodišnji žbun ili polužbun aromatičnog i oštrog mirisa zbog čega se koristi kao začinska biljka. Takođe je i ukrasna i medonosna biljka, ali i tradicionalni lek za bolesti organa za disanje i kod poremećaja varenja. Miloduh je cenjena eterično-aromatična biljka, a etarsko ulje se koristi u farmaceutskoj, parfimerijskoj i kozmetičkoj industriji kao i aromaterapiji. Cilj ovog istraživanja je bio da se determiniše hemijski sastav etarskog ulja miloduha kultivara „Domaći ljubičasti“ gajenog u Srbiji, i da se ispita antimikrobna aktivnost na 16 bakterija, uglavnom patogena u prehrambenoj industriji. Ukupno 61 komponenta je detektovana u etarskom ulju, pri čemu su monoterpenski ketoni cis-pinokamfon (43.8%) i trans-pinokamfon (18.3%) bili najzastupljeniji, čineći 62.1%, a potom slede β-pinen i pinokarvon. Etarsko ulje miloduha je ispoljilo antibakterijsku aktivnost na: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Proteus hauseri, Listeria monocytogenes, Rhodococcus equi, Listeria ivanovii, Salmonella Enteritidis, Enterococcus faecalis, Listeria innocua i Bacillus spizizenii, dok nije delovalo na Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella aerogenes i Staphylococcus epidermidis.",
publisher = "Belgrade : Centre for Evaluation in Education and Science",
journal = "Ratarstvo i Povrtarstvo",
title = "Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity, Hemijski sastav etarskog ulja miloduha kultivara  'Domaći ljubičasti' i ocena antimikrobne aktivnosti",
volume = "58",
number = "1",
pages = "23-30",
doi = "10.5937/ratpov58-31751"
}
Aćimović, M., Varga, A., Cvetković, M., Lato, P., Lončar, B., Ignjatov, M.,& Zeremski, T.. (2021). Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity. in Ratarstvo i Povrtarstvo
Belgrade : Centre for Evaluation in Education and Science., 58(1), 23-30.
https://doi.org/10.5937/ratpov58-31751
Aćimović M, Varga A, Cvetković M, Lato P, Lončar B, Ignjatov M, Zeremski T. Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity. in Ratarstvo i Povrtarstvo. 2021;58(1):23-30.
doi:10.5937/ratpov58-31751 .
Aćimović, Milica, Varga, Ana, Cvetković, Mirjana, Lato, Pezo, Lončar, Biljana, Ignjatov, Maja, Zeremski, Tijana, "Chemical composition of hyssop cv. 'Domaći ljubičasti' essential oil and its antimicrobial activity" in Ratarstvo i Povrtarstvo, 58, no. 1 (2021):23-30,
https://doi.org/10.5937/ratpov58-31751 . .
3
3

Chemical characterization of marrubium vulgare volatiles from Serbia

Aćimović, Milica G.; Ivanović, Stefan; Simić, Katarina; Pezo, Lato; Zeremski, Tijana; Ovuka, Jelena S.; Sikora, Vladimir Š.

(MDPI, 2021)

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Pezo, Lato
AU  - Zeremski, Tijana
AU  - Ovuka, Jelena S.
AU  - Sikora, Vladimir Š.
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4601
AB  - Marrubium vulgare is a cosmopolitan medicinal plant from the Lamiaceae family, which produces structurally highly diverse groups of secondary metabolites. A total of 160 compounds were determined in the volatiles from Serbia during two investigated years (2019 and 2020). The main components were E-caryophyllene, followed by germacrene D, α-humulene and α-copaene. All these compounds are from sesquiterpene hydrocarbons class which was dominant in both investigated years. This variation in volatiles composition could be a consequence of weather conditions, as in the case of other aromatic plants. According to the unrooted cluster tree with 37 samples of Marrubium sp. volatiles from literature and average values from this study, it could be said that there are several chemotypes: E-caryophyllene, β-bisabolene, α-pinene, β-farnesene, E-caryophyllene + caryophyllene oxide chemotype, and diverse (unclassified) chemotypes. However, occurring polymorphism could be consequence of adaptation to grow in different environment, especially ecological conditions such as humidity, temperature and altitude, as well as hybridization strongly affected the chemotypes. In addition, this paper aimed to obtain validated models for prediction of retention indices (RIs) of compounds isolated from M. vulgare volatiles. A total of 160 experimentally obtained RIs of volatile compounds was used to build the prediction models. The coefficients of determination were 0.956 and 0.964, demonstrating that these models could be used for predicting RIs, due to low prediction error and high r2 .
PB  - MDPI
T2  - Plants
T1  - Chemical characterization of marrubium vulgare volatiles from Serbia
VL  - 10
IS  - 3
SP  - 600
DO  - 10.3390/plants10030600
ER  - 
@article{
author = "Aćimović, Milica G. and Ivanović, Stefan and Simić, Katarina and Pezo, Lato and Zeremski, Tijana and Ovuka, Jelena S. and Sikora, Vladimir Š.",
year = "2021",
abstract = "Marrubium vulgare is a cosmopolitan medicinal plant from the Lamiaceae family, which produces structurally highly diverse groups of secondary metabolites. A total of 160 compounds were determined in the volatiles from Serbia during two investigated years (2019 and 2020). The main components were E-caryophyllene, followed by germacrene D, α-humulene and α-copaene. All these compounds are from sesquiterpene hydrocarbons class which was dominant in both investigated years. This variation in volatiles composition could be a consequence of weather conditions, as in the case of other aromatic plants. According to the unrooted cluster tree with 37 samples of Marrubium sp. volatiles from literature and average values from this study, it could be said that there are several chemotypes: E-caryophyllene, β-bisabolene, α-pinene, β-farnesene, E-caryophyllene + caryophyllene oxide chemotype, and diverse (unclassified) chemotypes. However, occurring polymorphism could be consequence of adaptation to grow in different environment, especially ecological conditions such as humidity, temperature and altitude, as well as hybridization strongly affected the chemotypes. In addition, this paper aimed to obtain validated models for prediction of retention indices (RIs) of compounds isolated from M. vulgare volatiles. A total of 160 experimentally obtained RIs of volatile compounds was used to build the prediction models. The coefficients of determination were 0.956 and 0.964, demonstrating that these models could be used for predicting RIs, due to low prediction error and high r2 .",
publisher = "MDPI",
journal = "Plants",
title = "Chemical characterization of marrubium vulgare volatiles from Serbia",
volume = "10",
number = "3",
pages = "600",
doi = "10.3390/plants10030600"
}
Aćimović, M. G., Ivanović, S., Simić, K., Pezo, L., Zeremski, T., Ovuka, J. S.,& Sikora, V. Š.. (2021). Chemical characterization of marrubium vulgare volatiles from Serbia. in Plants
MDPI., 10(3), 600.
https://doi.org/10.3390/plants10030600
Aćimović MG, Ivanović S, Simić K, Pezo L, Zeremski T, Ovuka JS, Sikora VŠ. Chemical characterization of marrubium vulgare volatiles from Serbia. in Plants. 2021;10(3):600.
doi:10.3390/plants10030600 .
Aćimović, Milica G., Ivanović, Stefan, Simić, Katarina, Pezo, Lato, Zeremski, Tijana, Ovuka, Jelena S., Sikora, Vladimir Š., "Chemical characterization of marrubium vulgare volatiles from Serbia" in Plants, 10, no. 3 (2021):600,
https://doi.org/10.3390/plants10030600 . .
7
8

Development of novel labelling system for microplastics

Teofilović, Vesna; Živković, Milica; Pucarević, Mira; Stojić, Nataša; Miletić, Srđan; Vrvić, Miroslav

(Oficyna Wydawnicza Politechniki Rzeszowskiej, 2021)

TY  - CONF
AU  - Teofilović, Vesna
AU  - Živković, Milica
AU  - Pucarević, Mira
AU  - Stojić, Nataša
AU  - Miletić, Srđan
AU  - Vrvić, Miroslav
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4951
AB  - Microplastics are microscopic pieces (<5 mm) of plastic materials that can be found at
every corner of our planet. Two ways of their release into the environment can be discerned: primary and secondary microplastics. While primary microplastics are released
directly into the environment as small particles, secondary microplastics are obtained by
breaking down from larger plastic items. Contamination of water and soil with microplastics transfers up the food chain, ends up in organisms and affects nature by changing
its biodiversity. EU legislative has restricted intentionally added microplastics in cosmetic products and issued stricter norms for products that usually release microplastics.
The use of certain single-use plastics is banned, use of lightweight plastics bags restricted, and the producers must cover up expenses for disposal of discarded plastic
packages. We are aware that a complete ban on plastics is not feasible. Nevertheless, it
is essential to notify of microplastics existence and its entire lifecycle. Labelling of
products that contain microplastics can be one of the ways to raise awareness. Informing
consumers about the composition of goods they are using, allows them to make more
conscious and responsible choices, both for themselves and the environment. There are
already some labels for microplastics, but they can be misleading since, if there are no
primary microplastics in the product, it does not mean that this product cannot affect
pollution as secondary microplastics. Therefore, we propose an extensive labelling system, which discerns between goods and packages, as well as between the primary and
secondary microplastics
PB  - Oficyna Wydawnicza Politechniki Rzeszowskiej
C3  - Environmental labels and declarations – normative aspects / Etykiety I deklaracje  środowiskowe  – aspekty normatywne
T1  - Development of novel labelling system for microplastics
SP  - 9
EP  - 18
UR  - https://hdl.handle.net/21.15107/rcub_cer_4951
ER  - 
@conference{
author = "Teofilović, Vesna and Živković, Milica and Pucarević, Mira and Stojić, Nataša and Miletić, Srđan and Vrvić, Miroslav",
year = "2021",
abstract = "Microplastics are microscopic pieces (<5 mm) of plastic materials that can be found at
every corner of our planet. Two ways of their release into the environment can be discerned: primary and secondary microplastics. While primary microplastics are released
directly into the environment as small particles, secondary microplastics are obtained by
breaking down from larger plastic items. Contamination of water and soil with microplastics transfers up the food chain, ends up in organisms and affects nature by changing
its biodiversity. EU legislative has restricted intentionally added microplastics in cosmetic products and issued stricter norms for products that usually release microplastics.
The use of certain single-use plastics is banned, use of lightweight plastics bags restricted, and the producers must cover up expenses for disposal of discarded plastic
packages. We are aware that a complete ban on plastics is not feasible. Nevertheless, it
is essential to notify of microplastics existence and its entire lifecycle. Labelling of
products that contain microplastics can be one of the ways to raise awareness. Informing
consumers about the composition of goods they are using, allows them to make more
conscious and responsible choices, both for themselves and the environment. There are
already some labels for microplastics, but they can be misleading since, if there are no
primary microplastics in the product, it does not mean that this product cannot affect
pollution as secondary microplastics. Therefore, we propose an extensive labelling system, which discerns between goods and packages, as well as between the primary and
secondary microplastics",
publisher = "Oficyna Wydawnicza Politechniki Rzeszowskiej",
journal = "Environmental labels and declarations – normative aspects / Etykiety I deklaracje  środowiskowe  – aspekty normatywne",
title = "Development of novel labelling system for microplastics",
pages = "9-18",
url = "https://hdl.handle.net/21.15107/rcub_cer_4951"
}
Teofilović, V., Živković, M., Pucarević, M., Stojić, N., Miletić, S.,& Vrvić, M.. (2021). Development of novel labelling system for microplastics. in Environmental labels and declarations – normative aspects / Etykiety I deklaracje  środowiskowe  – aspekty normatywne
Oficyna Wydawnicza Politechniki Rzeszowskiej., 9-18.
https://hdl.handle.net/21.15107/rcub_cer_4951
Teofilović V, Živković M, Pucarević M, Stojić N, Miletić S, Vrvić M. Development of novel labelling system for microplastics. in Environmental labels and declarations – normative aspects / Etykiety I deklaracje  środowiskowe  – aspekty normatywne. 2021;:9-18.
https://hdl.handle.net/21.15107/rcub_cer_4951 .
Teofilović, Vesna, Živković, Milica, Pucarević, Mira, Stojić, Nataša, Miletić, Srđan, Vrvić, Miroslav, "Development of novel labelling system for microplastics" in Environmental labels and declarations – normative aspects / Etykiety I deklaracje  środowiskowe  – aspekty normatywne (2021):9-18,
https://hdl.handle.net/21.15107/rcub_cer_4951 .

Bioremediation of soil polluted with oil

Teofilović, Vesna; Miletić, Srđan; Živković, Milica; Stojić, Nataša; Pucarević, Mira; Vrvić, Miroslav

(Čačak, Serbia : Univerzitet u Kragujevcu - Agronomski fakultet, Čačak, 2021)

TY  - JOUR
AU  - Teofilović, Vesna
AU  - Miletić, Srđan
AU  - Živković, Milica
AU  - Stojić, Nataša
AU  - Pucarević, Mira
AU  - Vrvić, Miroslav
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4964
AB  - Microplastics have reached all corners of our planet, including soil and water. Plastic-degrading bacteria are seen as a promising, environmentally friendly tool for the bioremediation of soil polluted with microplastics. The petroleum origin of plastics makes them candidates for bioremediation analogous to the bioremediation of soil polluted with oil and its derivatives. A mud pit,
located near the village of Turija, used for mud formation for the lubrication of drill pipes for drilling rigs, ended up polluted with
oil and its derivatives. It was bioremediated using the in situ procedure. The content of n-hexane extractable substance, total
petroleum hydrocarbon, dry substance, and loss on ignition were analyzed.
AB  - Микропластика се може наћи у сваком кутку наше планете, укључујући земљиште и водене површине. Сматра се да су бактерије које разграђују пластику будућност еколошки прихватљиве биоремедијације земљишта загађеног микропластиком. Због нафтног порекла, постоји оправдана сумња да се поступак биоремедијације земљишта загађеног нафтом и дериватима нафте адекватним избором микроорганизама може применити и код биоремедијације земљишта загађеног микропластиком. Исплачна јама у близини села Турија, која се користила за прављење исплаке за цеви за бушење нафтних бушотина, након завршетка бушотине, била је загађена нафтом и дериватима. Извршена је биоремедијација ин ситу поступком. Одређен је садржај супстанци растворних у хексану, укупних нафтних 
угљоводоника, суве супстанце и губитка при жарењу, непосредно пре и 90 и 180 дана након поступка биоремедијације.
PB  - Čačak, Serbia : Univerzitet u Kragujevcu - Agronomski fakultet, Čačak
T2  - Acta Agriculturae Serbica
T1  - Bioremediation of soil polluted with oil
VL  - 26
IS  - 51
SP  - 77
EP  - 81
DO  - 10.5937/AASer2151077T
ER  - 
@article{
author = "Teofilović, Vesna and Miletić, Srđan and Živković, Milica and Stojić, Nataša and Pucarević, Mira and Vrvić, Miroslav",
year = "2021",
abstract = "Microplastics have reached all corners of our planet, including soil and water. Plastic-degrading bacteria are seen as a promising, environmentally friendly tool for the bioremediation of soil polluted with microplastics. The petroleum origin of plastics makes them candidates for bioremediation analogous to the bioremediation of soil polluted with oil and its derivatives. A mud pit,
located near the village of Turija, used for mud formation for the lubrication of drill pipes for drilling rigs, ended up polluted with
oil and its derivatives. It was bioremediated using the in situ procedure. The content of n-hexane extractable substance, total
petroleum hydrocarbon, dry substance, and loss on ignition were analyzed., Микропластика се може наћи у сваком кутку наше планете, укључујући земљиште и водене површине. Сматра се да су бактерије које разграђују пластику будућност еколошки прихватљиве биоремедијације земљишта загађеног микропластиком. Због нафтног порекла, постоји оправдана сумња да се поступак биоремедијације земљишта загађеног нафтом и дериватима нафте адекватним избором микроорганизама може применити и код биоремедијације земљишта загађеног микропластиком. Исплачна јама у близини села Турија, која се користила за прављење исплаке за цеви за бушење нафтних бушотина, након завршетка бушотине, била је загађена нафтом и дериватима. Извршена је биоремедијација ин ситу поступком. Одређен је садржај супстанци растворних у хексану, укупних нафтних 
угљоводоника, суве супстанце и губитка при жарењу, непосредно пре и 90 и 180 дана након поступка биоремедијације.",
publisher = "Čačak, Serbia : Univerzitet u Kragujevcu - Agronomski fakultet, Čačak",
journal = "Acta Agriculturae Serbica",
title = "Bioremediation of soil polluted with oil",
volume = "26",
number = "51",
pages = "77-81",
doi = "10.5937/AASer2151077T"
}
Teofilović, V., Miletić, S., Živković, M., Stojić, N., Pucarević, M.,& Vrvić, M.. (2021). Bioremediation of soil polluted with oil. in Acta Agriculturae Serbica
Čačak, Serbia : Univerzitet u Kragujevcu - Agronomski fakultet, Čačak., 26(51), 77-81.
https://doi.org/10.5937/AASer2151077T
Teofilović V, Miletić S, Živković M, Stojić N, Pucarević M, Vrvić M. Bioremediation of soil polluted with oil. in Acta Agriculturae Serbica. 2021;26(51):77-81.
doi:10.5937/AASer2151077T .
Teofilović, Vesna, Miletić, Srđan, Živković, Milica, Stojić, Nataša, Pucarević, Mira, Vrvić, Miroslav, "Bioremediation of soil polluted with oil" in Acta Agriculturae Serbica, 26, no. 51 (2021):77-81,
https://doi.org/10.5937/AASer2151077T . .

Validnost baze podataka za spektre infracrvene spektroskopije sa Furijeovom transformacijom prilikom identifikacije mikroplastike

Teofilović, Vesna; Živković, Milica; Stojić, Nataša; Pucarević, Mira; Miletić, Srđan; Vrvić, Miroslav

(Belgrade, Serbia : Akademija tehničkih strukovnih studija, 2021)

TY  - CONF
AU  - Teofilović, Vesna
AU  - Živković, Milica
AU  - Stojić, Nataša
AU  - Pucarević, Mira
AU  - Miletić, Srđan
AU  - Vrvić, Miroslav
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4966
AB  - Mikroplastika, koja zbog malih dimenzija i male gustine lako dospeva do svih delova
Zemlje, je zaokupila pažnju naučne zajednice u poslednjoj deceniji. Najveća pažnja, posvećena je
uticaju, kao načinima unošenjana u ljudski organizam. Jedini način za sprečavanje ulaska
mikroplastike u lanac ishrane je poštovanje principa cirkularne ekonomije. Postoji veliki broj
različitih čestica mikroplastike u odnosu na vrstu polimera iz kojih su dobijene. Kako bi se
analiziralo poreklo čestica mikroplastike, neophodno ih je prvo izolovati, a zatim identifikovati.
Neke od metoda za identifikaciju mikroplastike su Infracrvena spektroskopija sa Furijeovom
transformacijom (FTIR), Raman spektroskopija, pirolitička gasna hromatrografija – masena
spektroskopija, od kojih su FTIR i RAMAN nedestruktivne metode. U radu je ispitan granulat 9
najčešće korišćenih komercijalnih polimera u izvornom obliku. Urađena je FTIR analiza, a dobijeni
rezultati poznatih polimera upoređeni su sa bazom podataka uređaja. Utvrđen je stepen
podudaranja sa pronađenim polimerom. Dobijeni rezultati su validirani u odnosu na deklarisane
polimere. Na osnovu dobijenih rezultata data su uputstva za dalju interpretaciju rezultata FTIR-a
prilikom identifikacije mikroplastike, kao i predlozi za buduća istraživanja.
AB  - Microplastics have captured the attention of the scientific community in the last decade. Due to small dimensions and low density, they can easily reach all parts of the Earth. Lately, the attention is shifted towards the health effects, and the pathways of entering into the human organism. The only way to prevent microplastics from entering the food chain is to respect the principles of circular economy. There are many different types of microplastic particles regarding the polymer from which they are obtained. In order to analyse the origin of microplastic particles, firstly it is necessary to isolate them, and then identify them. Some of the methods for identifying microplastics are Fourier-Transform Infrared Spectroscopy (FTIR), Raman spectroscopy, pyrolytic 
gas chromatography - mass spectroscopy, of which FTIR and RAMAN are non-destructive methods. This paper investigates beads of 9 most commonly used commercial polymers in their virgin form. FTIR analysis was performed, and the obtained results of known polymers were compared with the device database. The degree of matching with the found polymer was determined. The obtained results were validated in relation to the declared polymers. Based on the obtained results, instructions are given for further interpretation of FTIR results during the identification of microplastics, as well as suggestions for future research.
PB  - Belgrade, Serbia : Akademija tehničkih strukovnih studija
C3  - Zbornik radova - Šesti naučno-stručni skup Politehnika
T1  - Validnost baze podataka za spektre infracrvene spektroskopije sa Furijeovom transformacijom prilikom identifikacije mikroplastike
T1  - Fourier-trasform infrared spectroscopy spectra database validation for microplastics identification
SP  - 283
EP  - 288
UR  - https://hdl.handle.net/21.15107/rcub_cer_4966
ER  - 
@conference{
author = "Teofilović, Vesna and Živković, Milica and Stojić, Nataša and Pucarević, Mira and Miletić, Srđan and Vrvić, Miroslav",
year = "2021",
abstract = "Mikroplastika, koja zbog malih dimenzija i male gustine lako dospeva do svih delova
Zemlje, je zaokupila pažnju naučne zajednice u poslednjoj deceniji. Najveća pažnja, posvećena je
uticaju, kao načinima unošenjana u ljudski organizam. Jedini način za sprečavanje ulaska
mikroplastike u lanac ishrane je poštovanje principa cirkularne ekonomije. Postoji veliki broj
različitih čestica mikroplastike u odnosu na vrstu polimera iz kojih su dobijene. Kako bi se
analiziralo poreklo čestica mikroplastike, neophodno ih je prvo izolovati, a zatim identifikovati.
Neke od metoda za identifikaciju mikroplastike su Infracrvena spektroskopija sa Furijeovom
transformacijom (FTIR), Raman spektroskopija, pirolitička gasna hromatrografija – masena
spektroskopija, od kojih su FTIR i RAMAN nedestruktivne metode. U radu je ispitan granulat 9
najčešće korišćenih komercijalnih polimera u izvornom obliku. Urađena je FTIR analiza, a dobijeni
rezultati poznatih polimera upoređeni su sa bazom podataka uređaja. Utvrđen je stepen
podudaranja sa pronađenim polimerom. Dobijeni rezultati su validirani u odnosu na deklarisane
polimere. Na osnovu dobijenih rezultata data su uputstva za dalju interpretaciju rezultata FTIR-a
prilikom identifikacije mikroplastike, kao i predlozi za buduća istraživanja., Microplastics have captured the attention of the scientific community in the last decade. Due to small dimensions and low density, they can easily reach all parts of the Earth. Lately, the attention is shifted towards the health effects, and the pathways of entering into the human organism. The only way to prevent microplastics from entering the food chain is to respect the principles of circular economy. There are many different types of microplastic particles regarding the polymer from which they are obtained. In order to analyse the origin of microplastic particles, firstly it is necessary to isolate them, and then identify them. Some of the methods for identifying microplastics are Fourier-Transform Infrared Spectroscopy (FTIR), Raman spectroscopy, pyrolytic 
gas chromatography - mass spectroscopy, of which FTIR and RAMAN are non-destructive methods. This paper investigates beads of 9 most commonly used commercial polymers in their virgin form. FTIR analysis was performed, and the obtained results of known polymers were compared with the device database. The degree of matching with the found polymer was determined. The obtained results were validated in relation to the declared polymers. Based on the obtained results, instructions are given for further interpretation of FTIR results during the identification of microplastics, as well as suggestions for future research.",
publisher = "Belgrade, Serbia : Akademija tehničkih strukovnih studija",
journal = "Zbornik radova - Šesti naučno-stručni skup Politehnika",
title = "Validnost baze podataka za spektre infracrvene spektroskopije sa Furijeovom transformacijom prilikom identifikacije mikroplastike, Fourier-trasform infrared spectroscopy spectra database validation for microplastics identification",
pages = "283-288",
url = "https://hdl.handle.net/21.15107/rcub_cer_4966"
}
Teofilović, V., Živković, M., Stojić, N., Pucarević, M., Miletić, S.,& Vrvić, M.. (2021). Validnost baze podataka za spektre infracrvene spektroskopije sa Furijeovom transformacijom prilikom identifikacije mikroplastike. in Zbornik radova - Šesti naučno-stručni skup Politehnika
Belgrade, Serbia : Akademija tehničkih strukovnih studija., 283-288.
https://hdl.handle.net/21.15107/rcub_cer_4966
Teofilović V, Živković M, Stojić N, Pucarević M, Miletić S, Vrvić M. Validnost baze podataka za spektre infracrvene spektroskopije sa Furijeovom transformacijom prilikom identifikacije mikroplastike. in Zbornik radova - Šesti naučno-stručni skup Politehnika. 2021;:283-288.
https://hdl.handle.net/21.15107/rcub_cer_4966 .
Teofilović, Vesna, Živković, Milica, Stojić, Nataša, Pucarević, Mira, Miletić, Srđan, Vrvić, Miroslav, "Validnost baze podataka za spektre infracrvene spektroskopije sa Furijeovom transformacijom prilikom identifikacije mikroplastike" in Zbornik radova - Šesti naučno-stručni skup Politehnika (2021):283-288,
https://hdl.handle.net/21.15107/rcub_cer_4966 .

Pravni okvir i mogućnosti regulisanja problema mikroplastike u Srbiji

Teofilović, Vesna; Živković, Milica; Đajić, Sanja; Stojić, Nataša; Pucarević, Mira; Miletić, Srđan; Vrvić, Miroslav

(Srpsko društvo za zaštitu voda, 2021)

TY  - CONF
AU  - Teofilović, Vesna
AU  - Živković, Milica
AU  - Đajić, Sanja
AU  - Stojić, Nataša
AU  - Pucarević, Mira
AU  - Miletić, Srđan
AU  - Vrvić, Miroslav
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4965
AB  - Ne postoji deo planete do koga nije došla mikroplastika. Uticaj mikroplastike na čoveka se
još uvek ispituje. Ali dokazano je da se lancem ishrane unosi u organizam. Mikroplastika je
do sada pronađena u brojnim namirnicama za ljudsku ishranu. Osim toga, izaziva promene u
biodiverzitetu. Reke Srbije se ulivaju u tri morska sliva čime direktno utiču na zagađenje tih
mora. Stoga je važno da se Srbija uključi u borbu protiv mikroplastike. Zakonodavstvo EU
je prepoznalo problem mikroplastike. Iako Srbija usklađuje zakone i propise sa propisima
Evropske unije, nijedan zakon niti drugi propis ne smatra mikroplastiku zagađivačem. Pošto
je mikroplastika globalni problem, za njegovo rešavanje neophodno je udružiti snage, i
zajedničkim delovanjem države, nevladinog sektora, naučne zajednice, pojedinaca, ali u
najvećoj meri i samih kompanija krenuti u akciju.
AB  - There is no part of the planet that has not been contaminated with microplastics. The impact of microplastics on humans is still being investigated. But it has been proven that it is taken into the body through the food chain. Microplastics have so far been found in a number of foods for human consumption. In addition, it causes changes in biodiversity. The rivers of Serbia flow into three sea basins, which directly affects the pollution of those seas. Therefore, it is important for Serbia to get involved in the fight against microplastics. EU legislation has recognized the problem of 
 microplastics. Although Serbia harmonizes laws and regulations with the regulations of the European Union (EU), no law or other regulation considers microplastics as a pollutant. Since microplastics is a global problem, in order to solve it, it is necessary to join forces, and by joint action of the Government, the scientific community, individuals, but mostly of the companies themselves, to take action.
PB  - Srpsko društvo za zaštitu voda
C3  - Conference Proceedings - 50. konferencija o aktuelnim temama korišćenja i zaštite voda - VODA 2021 The 50th Annual Conference of the Serbian Water Pollution Control Society - WATER 2021
T1  - Pravni okvir i mogućnosti regulisanja problema mikroplastike u Srbiji
T1  - Legal framework and possibilities for regulation of microplastics content in waters in Serbia
SP  - 9
EP  - 16
UR  - https://hdl.handle.net/21.15107/rcub_cer_4965
ER  - 
@conference{
author = "Teofilović, Vesna and Živković, Milica and Đajić, Sanja and Stojić, Nataša and Pucarević, Mira and Miletić, Srđan and Vrvić, Miroslav",
year = "2021",
abstract = "Ne postoji deo planete do koga nije došla mikroplastika. Uticaj mikroplastike na čoveka se
još uvek ispituje. Ali dokazano je da se lancem ishrane unosi u organizam. Mikroplastika je
do sada pronađena u brojnim namirnicama za ljudsku ishranu. Osim toga, izaziva promene u
biodiverzitetu. Reke Srbije se ulivaju u tri morska sliva čime direktno utiču na zagađenje tih
mora. Stoga je važno da se Srbija uključi u borbu protiv mikroplastike. Zakonodavstvo EU
je prepoznalo problem mikroplastike. Iako Srbija usklađuje zakone i propise sa propisima
Evropske unije, nijedan zakon niti drugi propis ne smatra mikroplastiku zagađivačem. Pošto
je mikroplastika globalni problem, za njegovo rešavanje neophodno je udružiti snage, i
zajedničkim delovanjem države, nevladinog sektora, naučne zajednice, pojedinaca, ali u
najvećoj meri i samih kompanija krenuti u akciju., There is no part of the planet that has not been contaminated with microplastics. The impact of microplastics on humans is still being investigated. But it has been proven that it is taken into the body through the food chain. Microplastics have so far been found in a number of foods for human consumption. In addition, it causes changes in biodiversity. The rivers of Serbia flow into three sea basins, which directly affects the pollution of those seas. Therefore, it is important for Serbia to get involved in the fight against microplastics. EU legislation has recognized the problem of 
 microplastics. Although Serbia harmonizes laws and regulations with the regulations of the European Union (EU), no law or other regulation considers microplastics as a pollutant. Since microplastics is a global problem, in order to solve it, it is necessary to join forces, and by joint action of the Government, the scientific community, individuals, but mostly of the companies themselves, to take action.",
publisher = "Srpsko društvo za zaštitu voda",
journal = "Conference Proceedings - 50. konferencija o aktuelnim temama korišćenja i zaštite voda - VODA 2021 The 50th Annual Conference of the Serbian Water Pollution Control Society - WATER 2021",
title = "Pravni okvir i mogućnosti regulisanja problema mikroplastike u Srbiji, Legal framework and possibilities for regulation of microplastics content in waters in Serbia",
pages = "9-16",
url = "https://hdl.handle.net/21.15107/rcub_cer_4965"
}
Teofilović, V., Živković, M., Đajić, S., Stojić, N., Pucarević, M., Miletić, S.,& Vrvić, M.. (2021). Pravni okvir i mogućnosti regulisanja problema mikroplastike u Srbiji. in Conference Proceedings - 50. konferencija o aktuelnim temama korišćenja i zaštite voda - VODA 2021 The 50th Annual Conference of the Serbian Water Pollution Control Society - WATER 2021
Srpsko društvo za zaštitu voda., 9-16.
https://hdl.handle.net/21.15107/rcub_cer_4965
Teofilović V, Živković M, Đajić S, Stojić N, Pucarević M, Miletić S, Vrvić M. Pravni okvir i mogućnosti regulisanja problema mikroplastike u Srbiji. in Conference Proceedings - 50. konferencija o aktuelnim temama korišćenja i zaštite voda - VODA 2021 The 50th Annual Conference of the Serbian Water Pollution Control Society - WATER 2021. 2021;:9-16.
https://hdl.handle.net/21.15107/rcub_cer_4965 .
Teofilović, Vesna, Živković, Milica, Đajić, Sanja, Stojić, Nataša, Pucarević, Mira, Miletić, Srđan, Vrvić, Miroslav, "Pravni okvir i mogućnosti regulisanja problema mikroplastike u Srbiji" in Conference Proceedings - 50. konferencija o aktuelnim temama korišćenja i zaštite voda - VODA 2021 The 50th Annual Conference of the Serbian Water Pollution Control Society - WATER 2021 (2021):9-16,
https://hdl.handle.net/21.15107/rcub_cer_4965 .