TY  - JOUR
AU  - Petkovic, Milos
AU  - Nasufovic, Veselin
AU  - Đukanović, Dimitrije
AU  - Vujosevic, Zorana Tokic
AU  - Jadranin, Milka
AU  - Matović, Radomir
AU  - Savić, Vladimir
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2040
AB  - Allenamides derived from amino acids participate in the cascade transformations catalyzed by Pd-0 allowing consecutive formation of two five-membered rings. The developed methodology provides an access to annulated indoles which can be transformed to functionalized indoxyl derivatives, retaining a structural motif embedded in several natural products.
PB  - Wiley-VCH Verlag
T2  - European Journal of Organic Chemistry
T1  - Cyclative Cascades of Allenamides Derived from Amino Acids: Synthesis of Annulated Indoxyl Derivatives
IS  - 7
SP  - 1279
EP  - 1282
DO  - 10.1002/ejoc.201600067
ER  - 

@article{
author = "Petkovic, Milos and Nasufovic, Veselin and Đukanović, Dimitrije and Vujosevic, Zorana Tokic and Jadranin, Milka and Matović, Radomir and Savić, Vladimir",
year = "2016",
abstract = "Allenamides derived from amino acids participate in the cascade transformations catalyzed by Pd-0 allowing consecutive formation of two five-membered rings. The developed methodology provides an access to annulated indoles which can be transformed to functionalized indoxyl derivatives, retaining a structural motif embedded in several natural products.",
publisher = "Wiley-VCH Verlag",
journal = "European Journal of Organic Chemistry",
title = "Cyclative Cascades of Allenamides Derived from Amino Acids: Synthesis of Annulated Indoxyl Derivatives",
number = "7",
pages = "1279-1282",
doi = "10.1002/ejoc.201600067"
}

Petkovic, M., Nasufovic, V., Đukanović, D., Vujosevic, Z. T., Jadranin, M., Matović, R.,& Savić, V.. (2016). Cyclative Cascades of Allenamides Derived from Amino Acids: Synthesis of Annulated Indoxyl Derivatives. in European Journal of Organic Chemistry
Wiley-VCH Verlag.(7), 1279-1282.
https://doi.org/10.1002/ejoc.201600067

Petkovic M, Nasufovic V, Đukanović D, Vujosevic ZT, Jadranin M, Matović R, Savić V. Cyclative Cascades of Allenamides Derived from Amino Acids: Synthesis of Annulated Indoxyl Derivatives. in European Journal of Organic Chemistry. 2016;(7):1279-1282.
doi:10.1002/ejoc.201600067 .

Petkovic, Milos, Nasufovic, Veselin, Đukanović, Dimitrije, Vujosevic, Zorana Tokic, Jadranin, Milka, Matović, Radomir, Savić, Vladimir, "Cyclative Cascades of Allenamides Derived from Amino Acids: Synthesis of Annulated Indoxyl Derivatives" in European Journal of Organic Chemistry, no. 7 (2016):1279-1282,
https://doi.org/10.1002/ejoc.201600067 . .

TY  - JOUR
AU  - Tasic, Gordana
AU  - Maslak, Veselin
AU  - Husinec, Suren
AU  - Todorović, Nina
AU  - Savić, Vladimir
PY  - 2015
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1740
AB  - The intramolecular Heck reaction has been examined for the preparation of the core bicyclic structure of corialstonidine. Initial attempts to cyclise a vinyl iodide moiety onto a cyclic allyl alcohol were complicated by various side reactions. However, the corresponding process performed under reductive conditions on a conjugated ketone, obtained from the cyclic allyl alcohol, afforded the desired bicyclo[3.2.1] derivative. This compound possesses the skeletal features of the carbocyclic fragment of corialstonidine and is suitable for further transformations aimed towards the synthesis of the natural product or its derivatives.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Tetrahedron Letters
T1  - Study of the intramolecular Heck reaction: synthesis of the bicyclic core of corialstonidine
VL  - 56
IS  - 19
SP  - 2529
EP  - 2532
DO  - 10.1016/j.tetlet.2015.03.129
ER  - 

@article{
author = "Tasic, Gordana and Maslak, Veselin and Husinec, Suren and Todorović, Nina and Savić, Vladimir",
year = "2015",
abstract = "The intramolecular Heck reaction has been examined for the preparation of the core bicyclic structure of corialstonidine. Initial attempts to cyclise a vinyl iodide moiety onto a cyclic allyl alcohol were complicated by various side reactions. However, the corresponding process performed under reductive conditions on a conjugated ketone, obtained from the cyclic allyl alcohol, afforded the desired bicyclo[3.2.1] derivative. This compound possesses the skeletal features of the carbocyclic fragment of corialstonidine and is suitable for further transformations aimed towards the synthesis of the natural product or its derivatives.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron Letters",
title = "Study of the intramolecular Heck reaction: synthesis of the bicyclic core of corialstonidine",
volume = "56",
number = "19",
pages = "2529-2532",
doi = "10.1016/j.tetlet.2015.03.129"
}

Tasic, G., Maslak, V., Husinec, S., Todorović, N.,& Savić, V.. (2015). Study of the intramolecular Heck reaction: synthesis of the bicyclic core of corialstonidine. in Tetrahedron Letters
Oxford : Pergamon-Elsevier Science Ltd., 56(19), 2529-2532.
https://doi.org/10.1016/j.tetlet.2015.03.129

Tasic G, Maslak V, Husinec S, Todorović N, Savić V. Study of the intramolecular Heck reaction: synthesis of the bicyclic core of corialstonidine. in Tetrahedron Letters. 2015;56(19):2529-2532.
doi:10.1016/j.tetlet.2015.03.129 .

Tasic, Gordana, Maslak, Veselin, Husinec, Suren, Todorović, Nina, Savić, Vladimir, "Study of the intramolecular Heck reaction: synthesis of the bicyclic core of corialstonidine" in Tetrahedron Letters, 56, no. 19 (2015):2529-2532,
https://doi.org/10.1016/j.tetlet.2015.03.129 . .

TY  - JOUR
AU  - Tasić, Gordana
AU  - Simić, Milena R.
AU  - Popović, Stanimir
AU  - Husinec, Suren
AU  - Maslak, Veselin
AU  - Savić, Vladimir
PY  - 2013
UR  - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1973
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3503
AB  - Double bond migration in N-allylindoles has been investigated as a method to access N-vinyl derivatives of this heterocycle. The optimal reaction conditions employed t-BuOK or NaH in DMSO as the solvent at room temperature to afford the products in yields ranging from 51 to 99%. Although in some cases a high degree of stereoselectivity was observed, preferential formation of either the Z- or E-isomer was not predictable. The developed methodology was employed in the synthesis of (+/-)-debromoarborescidine B.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Tetrahedron-Asymmetry
T1  - Indirect N-vinylation of indoles via isomerisation of N-allyl derivatives: synthesis of (+/-)-debromoarborescidine B
VL  - 54
IS  - 34
SP  - 4536
EP  - 4539
DO  - 10.1016/j.tetlet.2013.06.069
ER  - 

@article{
author = "Tasić, Gordana and Simić, Milena R. and Popović, Stanimir and Husinec, Suren and Maslak, Veselin and Savić, Vladimir",
year = "2013",
abstract = "Double bond migration in N-allylindoles has been investigated as a method to access N-vinyl derivatives of this heterocycle. The optimal reaction conditions employed t-BuOK or NaH in DMSO as the solvent at room temperature to afford the products in yields ranging from 51 to 99%. Although in some cases a high degree of stereoselectivity was observed, preferential formation of either the Z- or E-isomer was not predictable. The developed methodology was employed in the synthesis of (+/-)-debromoarborescidine B.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron-Asymmetry",
title = "Indirect N-vinylation of indoles via isomerisation of N-allyl derivatives: synthesis of (+/-)-debromoarborescidine B",
volume = "54",
number = "34",
pages = "4536-4539",
doi = "10.1016/j.tetlet.2013.06.069"
}

Tasić, G., Simić, M. R., Popović, S., Husinec, S., Maslak, V.,& Savić, V.. (2013). Indirect N-vinylation of indoles via isomerisation of N-allyl derivatives: synthesis of (+/-)-debromoarborescidine B. in Tetrahedron-Asymmetry
Oxford : Pergamon-Elsevier Science Ltd., 54(34), 4536-4539.
https://doi.org/10.1016/j.tetlet.2013.06.069

Tasić G, Simić MR, Popović S, Husinec S, Maslak V, Savić V. Indirect N-vinylation of indoles via isomerisation of N-allyl derivatives: synthesis of (+/-)-debromoarborescidine B. in Tetrahedron-Asymmetry. 2013;54(34):4536-4539.
doi:10.1016/j.tetlet.2013.06.069 .

Tasić, Gordana, Simić, Milena R., Popović, Stanimir, Husinec, Suren, Maslak, Veselin, Savić, Vladimir, "Indirect N-vinylation of indoles via isomerisation of N-allyl derivatives: synthesis of (+/-)-debromoarborescidine B" in Tetrahedron-Asymmetry, 54, no. 34 (2013):4536-4539,
https://doi.org/10.1016/j.tetlet.2013.06.069 . .

TY  - JOUR
AU  - Tasić, Gordana
AU  - Ranđelović, Jelena
AU  - Vusurović, Nikola
AU  - Maslak, Veselin
AU  - Husinec, Suren
AU  - Savić, Vladimir
PY  - 2013
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/1586
UR  - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1924
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3504
AB  - Intramolecular Pd-catalysed cyclisation reactions for the preparation of bicyclic compounds have been studied as a model system towards the synthesis of corialstonine and corialstonidine. Significant differences in reactivity have been observed for the cyclic allyl alcohols possessing O-protected and free OH functionalities. Cyclisation via the intramolecular Heck reaction, for both derivatives, proved to be highly regioselective and while the O-protected compound favoured the exo mode of cyclisation, the unprotected alcohol preferred the endo cyclisation pathway. Brief computational studies were carried out in order to obtain further insight into these processes.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Tetrahedron Letters
T1  - A highly regioselective, protecting group controlled, synthesis of bicyclic compounds via Pd-catalysed intramolecular cyclisations
VL  - 54
IS  - 18
SP  - 2243
EP  - 2246
DO  - 10.1016/j.tetlet.2013.02.068
ER  - 

@article{
author = "Tasić, Gordana and Ranđelović, Jelena and Vusurović, Nikola and Maslak, Veselin and Husinec, Suren and Savić, Vladimir",
year = "2013",
abstract = "Intramolecular Pd-catalysed cyclisation reactions for the preparation of bicyclic compounds have been studied as a model system towards the synthesis of corialstonine and corialstonidine. Significant differences in reactivity have been observed for the cyclic allyl alcohols possessing O-protected and free OH functionalities. Cyclisation via the intramolecular Heck reaction, for both derivatives, proved to be highly regioselective and while the O-protected compound favoured the exo mode of cyclisation, the unprotected alcohol preferred the endo cyclisation pathway. Brief computational studies were carried out in order to obtain further insight into these processes.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron Letters",
title = "A highly regioselective, protecting group controlled, synthesis of bicyclic compounds via Pd-catalysed intramolecular cyclisations",
volume = "54",
number = "18",
pages = "2243-2246",
doi = "10.1016/j.tetlet.2013.02.068"
}

Tasić, G., Ranđelović, J., Vusurović, N., Maslak, V., Husinec, S.,& Savić, V.. (2013). A highly regioselective, protecting group controlled, synthesis of bicyclic compounds via Pd-catalysed intramolecular cyclisations. in Tetrahedron Letters
Oxford : Pergamon-Elsevier Science Ltd., 54(18), 2243-2246.
https://doi.org/10.1016/j.tetlet.2013.02.068

Tasić G, Ranđelović J, Vusurović N, Maslak V, Husinec S, Savić V. A highly regioselective, protecting group controlled, synthesis of bicyclic compounds via Pd-catalysed intramolecular cyclisations. in Tetrahedron Letters. 2013;54(18):2243-2246.
doi:10.1016/j.tetlet.2013.02.068 .

Tasić, Gordana, Ranđelović, Jelena, Vusurović, Nikola, Maslak, Veselin, Husinec, Suren, Savić, Vladimir, "A highly regioselective, protecting group controlled, synthesis of bicyclic compounds via Pd-catalysed intramolecular cyclisations" in Tetrahedron Letters, 54, no. 18 (2013):2243-2246,
https://doi.org/10.1016/j.tetlet.2013.02.068 . .

TY  - JOUR
AU  - Husinec, Suren
AU  - Petković, Miloš
AU  - Savić, Vladimir
AU  - Simić, Milena
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4173
AB  - pi-Allylpalladium intermediates are known to participate efficiently in transformations involving nucleophilic species. Exploring these processes, we have developed a method for the preparation of allyl acetates via palladium-catalysed functionalisation of allenes and 1,3-dienes. Reactions of aryl iodides with either of these two classes of compounds and excess sodium acetate in the presence of Pd(OAc) (2) and Ph3P as the catalytic system afforded the respective allyl acetates in moderate to good yields. The scope of this process has been investigated. The described method is an addition to the synthetic repertoire for the preparation of allyl acetates, and may be useful, in particular, for the synthesis of structurally complex compounds of this type.
PB  - Stuttgart : Georg Thieme Verlag Kg
T2  - Synthesis
T1  - Synthesis of Allyl Acetates via Palladium-Catalysed Functionalisation of Allenes and 1,3-Dienes
VL  - 44
IS  - 3
SP  - 399
EP  - 408
DO  - 10.1055/s-0031-1289658
ER  - 

@article{
author = "Husinec, Suren and Petković, Miloš and Savić, Vladimir and Simić, Milena",
year = "2012",
abstract = "pi-Allylpalladium intermediates are known to participate efficiently in transformations involving nucleophilic species. Exploring these processes, we have developed a method for the preparation of allyl acetates via palladium-catalysed functionalisation of allenes and 1,3-dienes. Reactions of aryl iodides with either of these two classes of compounds and excess sodium acetate in the presence of Pd(OAc) (2) and Ph3P as the catalytic system afforded the respective allyl acetates in moderate to good yields. The scope of this process has been investigated. The described method is an addition to the synthetic repertoire for the preparation of allyl acetates, and may be useful, in particular, for the synthesis of structurally complex compounds of this type.",
publisher = "Stuttgart : Georg Thieme Verlag Kg",
journal = "Synthesis",
title = "Synthesis of Allyl Acetates via Palladium-Catalysed Functionalisation of Allenes and 1,3-Dienes",
volume = "44",
number = "3",
pages = "399-408",
doi = "10.1055/s-0031-1289658"
}

Husinec, S., Petković, M., Savić, V.,& Simić, M.. (2012). Synthesis of Allyl Acetates via Palladium-Catalysed Functionalisation of Allenes and 1,3-Dienes. in Synthesis
Stuttgart : Georg Thieme Verlag Kg., 44(3), 399-408.
https://doi.org/10.1055/s-0031-1289658

Husinec S, Petković M, Savić V, Simić M. Synthesis of Allyl Acetates via Palladium-Catalysed Functionalisation of Allenes and 1,3-Dienes. in Synthesis. 2012;44(3):399-408.
doi:10.1055/s-0031-1289658 .

Husinec, Suren, Petković, Miloš, Savić, Vladimir, Simić, Milena, "Synthesis of Allyl Acetates via Palladium-Catalysed Functionalisation of Allenes and 1,3-Dienes" in Synthesis, 44, no. 3 (2012):399-408,
https://doi.org/10.1055/s-0031-1289658 . .

TY  - JOUR
AU  - Husinec, Suren
AU  - Savić, Vladimir
AU  - Simić, Milena R.
AU  - Tešević, Vele
AU  - Vidović, Dragoslav
PY  - 2011
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/1342
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3505
UR  - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1567
AB  - Annulation processes of isoquinoline and p-carboline compounds have been investigated leading to synthetic routes for the preparation of 8-oxoprotoberberine derivatives. The key steps combined a diene formation/Diels-Alder cycloaddition reaction to afford the targeted polycyclic skeletons. Further oxidative transformations of the cycloadducts produced the 8-oxoprotoberberine type products. The alkaloids of this class are important natural products with a wide range of biological activity and the synthethic methodology described in this paper could prove to be useful for the preparation of the D-ring functionalised derivatives.
PB  - Oxford : Pergamon-Elsevier Science Ltd
T2  - Tetrahedron Letters
T1  - Annulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives
VL  - 52
IS  - 21
SP  - 2733
EP  - 2736
DO  - 10.1016/j.tetlet.2011.03.085
ER  - 

@article{
author = "Husinec, Suren and Savić, Vladimir and Simić, Milena R. and Tešević, Vele and Vidović, Dragoslav",
year = "2011",
abstract = "Annulation processes of isoquinoline and p-carboline compounds have been investigated leading to synthetic routes for the preparation of 8-oxoprotoberberine derivatives. The key steps combined a diene formation/Diels-Alder cycloaddition reaction to afford the targeted polycyclic skeletons. Further oxidative transformations of the cycloadducts produced the 8-oxoprotoberberine type products. The alkaloids of this class are important natural products with a wide range of biological activity and the synthethic methodology described in this paper could prove to be useful for the preparation of the D-ring functionalised derivatives.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron Letters",
title = "Annulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives",
volume = "52",
number = "21",
pages = "2733-2736",
doi = "10.1016/j.tetlet.2011.03.085"
}

Husinec, S., Savić, V., Simić, M. R., Tešević, V.,& Vidović, D.. (2011). Annulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives. in Tetrahedron Letters
Oxford : Pergamon-Elsevier Science Ltd., 52(21), 2733-2736.
https://doi.org/10.1016/j.tetlet.2011.03.085

Husinec S, Savić V, Simić MR, Tešević V, Vidović D. Annulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives. in Tetrahedron Letters. 2011;52(21):2733-2736.
doi:10.1016/j.tetlet.2011.03.085 .

Husinec, Suren, Savić, Vladimir, Simić, Milena R., Tešević, Vele, Vidović, Dragoslav, "Annulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives" in Tetrahedron Letters, 52, no. 21 (2011):2733-2736,
https://doi.org/10.1016/j.tetlet.2011.03.085 . .

TY  - JOUR
AU  - Husinec, Suren
AU  - Marković, Rade
AU  - Petković, Miloš
AU  - Nasufović, Veselin
AU  - Savić, Vladimir
PY  - 2011
UR  - http://farfar.pharmacy.bg.ac.rs/handle/123456789/1527
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3506
AB  - A base promoted cyclization of the protected N-propargylaminopyridines was shown to be an efficient method for the preparation of imidazo[1,2-a] pyridine derivatives. The reactions were carried out with a small excess of base, at room temperature or slightly above producing the heterocyclic products in moderate to good yields. The stereoelectronic properties of substituents on the pyridine ring were shown to influence the cyclization process.
PB  - American Chemical Society (ACS)
T2  - Organic Letters
T1  - A Base Promoted Cyclization of N-Propargylaminopyridines. Synthesis of Imidazo[1,2-a]pyridine Derivatives
VL  - 13
IS  - 9
SP  - 2286
EP  - 2289
DO  - 10.1021/ol200508x
ER  - 

@article{
author = "Husinec, Suren and Marković, Rade and Petković, Miloš and Nasufović, Veselin and Savić, Vladimir",
year = "2011",
abstract = "A base promoted cyclization of the protected N-propargylaminopyridines was shown to be an efficient method for the preparation of imidazo[1,2-a] pyridine derivatives. The reactions were carried out with a small excess of base, at room temperature or slightly above producing the heterocyclic products in moderate to good yields. The stereoelectronic properties of substituents on the pyridine ring were shown to influence the cyclization process.",
publisher = "American Chemical Society (ACS)",
journal = "Organic Letters",
title = "A Base Promoted Cyclization of N-Propargylaminopyridines. Synthesis of Imidazo[1,2-a]pyridine Derivatives",
volume = "13",
number = "9",
pages = "2286-2289",
doi = "10.1021/ol200508x"
}

Husinec, S., Marković, R., Petković, M., Nasufović, V.,& Savić, V.. (2011). A Base Promoted Cyclization of N-Propargylaminopyridines. Synthesis of Imidazo[1,2-a]pyridine Derivatives. in Organic Letters
American Chemical Society (ACS)., 13(9), 2286-2289.
https://doi.org/10.1021/ol200508x

Husinec S, Marković R, Petković M, Nasufović V, Savić V. A Base Promoted Cyclization of N-Propargylaminopyridines. Synthesis of Imidazo[1,2-a]pyridine Derivatives. in Organic Letters. 2011;13(9):2286-2289.
doi:10.1021/ol200508x .

Husinec, Suren, Marković, Rade, Petković, Miloš, Nasufović, Veselin, Savić, Vladimir, "A Base Promoted Cyclization of N-Propargylaminopyridines. Synthesis of Imidazo[1,2-a]pyridine Derivatives" in Organic Letters, 13, no. 9 (2011):2286-2289,
https://doi.org/10.1021/ol200508x . .