TY  - CONF
AU  - Srećo Zelenović, Bojana
AU  - Kekezović, Slađana
AU  - Kojić, Vesna V.
AU  - Benedeković, Goran
AU  - Jadranin, Milka
AU  - Popsavin, Mirjana
AU  - Popsavin, Velimir
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7275
AB  - (-)-Goniofufurone (1) is a synthetic styryl lactone that exhibits significant antitumor activity. In the search for new and more potent antitumor agents the synthesis of lactones 5 and 6 was planned from D-glucose. Compounds 5 and 6 are designed as dephenylated analogues of 1 (Figure 1). The results of the evaluation of antiproliferative activity of 5 and 6 against a number of human tumor cell lines, as well as the structure-activity relationship (SAR), will be presented and discussed in details.
PB  - Valahia University of Targoviste
PB  - University Politehnica of Bucharest
C3  - Book of Abstracts - 9th International Conferences of the Chemical Societies of the South-Eastern European Countries, ICOSECS9, "Chemistry a Nature Challenger", Targoviste, Romania
T1  - Synthesis and antitumour activity of two dephenilated (-)-goniofufurone analogues
SP  - S3_P16
EP  - S3_P16
UR  - https://hdl.handle.net/21.15107/rcub_cer_7275
ER  - 

@conference{
author = "Srećo Zelenović, Bojana and Kekezović, Slađana and Kojić, Vesna V. and Benedeković, Goran and Jadranin, Milka and Popsavin, Mirjana and Popsavin, Velimir",
year = "2019",
abstract = "(-)-Goniofufurone (1) is a synthetic styryl lactone that exhibits significant antitumor activity. In the search for new and more potent antitumor agents the synthesis of lactones 5 and 6 was planned from D-glucose. Compounds 5 and 6 are designed as dephenylated analogues of 1 (Figure 1). The results of the evaluation of antiproliferative activity of 5 and 6 against a number of human tumor cell lines, as well as the structure-activity relationship (SAR), will be presented and discussed in details.",
publisher = "Valahia University of Targoviste, University Politehnica of Bucharest",
journal = "Book of Abstracts - 9th International Conferences of the Chemical Societies of the South-Eastern European Countries, ICOSECS9, "Chemistry a Nature Challenger", Targoviste, Romania",
title = "Synthesis and antitumour activity of two dephenilated (-)-goniofufurone analogues",
pages = "S3_P16-S3_P16",
url = "https://hdl.handle.net/21.15107/rcub_cer_7275"
}

Srećo Zelenović, B., Kekezović, S., Kojić, V. V., Benedeković, G., Jadranin, M., Popsavin, M.,& Popsavin, V.. (2019). Synthesis and antitumour activity of two dephenilated (-)-goniofufurone analogues. in Book of Abstracts - 9th International Conferences of the Chemical Societies of the South-Eastern European Countries, ICOSECS9, "Chemistry a Nature Challenger", Targoviste, Romania
Valahia University of Targoviste., S3_P16-S3_P16.
https://hdl.handle.net/21.15107/rcub_cer_7275

Srećo Zelenović B, Kekezović S, Kojić VV, Benedeković G, Jadranin M, Popsavin M, Popsavin V. Synthesis and antitumour activity of two dephenilated (-)-goniofufurone analogues. in Book of Abstracts - 9th International Conferences of the Chemical Societies of the South-Eastern European Countries, ICOSECS9, "Chemistry a Nature Challenger", Targoviste, Romania. 2019;:S3_P16-S3_P16.
https://hdl.handle.net/21.15107/rcub_cer_7275 .

Srećo Zelenović, Bojana, Kekezović, Slađana, Kojić, Vesna V., Benedeković, Goran, Jadranin, Milka, Popsavin, Mirjana, Popsavin, Velimir, "Synthesis and antitumour activity of two dephenilated (-)-goniofufurone analogues" in Book of Abstracts - 9th International Conferences of the Chemical Societies of the South-Eastern European Countries, ICOSECS9, "Chemistry a Nature Challenger", Targoviste, Romania (2019):S3_P16-S3_P16,
https://hdl.handle.net/21.15107/rcub_cer_7275 .

TY  - CONF
AU  - Popsavin, Mirjana
AU  - Kovačević, Ivana
AU  - Kekezović, Slađana
AU  - Svirčev, Miloš
AU  - Srećo Zelenović, Bojana
AU  - Kojić, Vesna V.
AU  - Jadranin, Milka
AU  - Popsavin, Velimir
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7095
AB  - Ostvarena je višefazna sinteza novih mimetika (+)-goniofufurona (1) sa tiofenskim prstenom umesto fenil grupe u položaju C-7 polazeći iz D-glukoze (Shema 1). Ispitana je in vitro citotoksična aktivnost novosintetizovanih mimetika prema odabranim tumorskim ćelijskim linijama, kao i prema jednoj normalnoj ćelijskoj liniji (fetalni fibroblasti pluća, MRC-5).
AB  - Multiphase synthesis of (+)-goniofufurone (1) mimetics with thiofene ring instead of phenyl group at the C-7 position is completed using D-glucose as a starting compound (Scheme 1). In vitro cytotoxicity of newly synthetized analogues against eleven human tumour cell lines and against a single normal cell line (MRC-5) was evaluated.
PB  - Belgrade : Serbian Chemical Society
C3  - Kratki izvodi radova - 55. Savetovanje Srpskog hemijskog društva, 8. i 9. juni 2018, Novi Sad / Book of abstracts - 55 Meeting of the Serbian Chemical Society, June 8-9, 2018, Novi Sad
T1  - Sinteza i in vitro antitumourska aktivnost novih mimetika goniofufurona sa tiofenskim prstenom na položaju C-7
T1  - Synthesis and in vitro antitumour activity of new goniofufurone mimics with  thiophene ring at the C-7 position
SP  - 82
EP  - 82
UR  - https://hdl.handle.net/21.15107/rcub_cer_7095
ER  - 

@conference{
author = "Popsavin, Mirjana and Kovačević, Ivana and Kekezović, Slađana and Svirčev, Miloš and Srećo Zelenović, Bojana and Kojić, Vesna V. and Jadranin, Milka and Popsavin, Velimir",
year = "2018",
abstract = "Ostvarena je višefazna sinteza novih mimetika (+)-goniofufurona (1) sa tiofenskim prstenom umesto fenil grupe u položaju C-7 polazeći iz D-glukoze (Shema 1). Ispitana je in vitro citotoksična aktivnost novosintetizovanih mimetika prema odabranim tumorskim ćelijskim linijama, kao i prema jednoj normalnoj ćelijskoj liniji (fetalni fibroblasti pluća, MRC-5)., Multiphase synthesis of (+)-goniofufurone (1) mimetics with thiofene ring instead of phenyl group at the C-7 position is completed using D-glucose as a starting compound (Scheme 1). In vitro cytotoxicity of newly synthetized analogues against eleven human tumour cell lines and against a single normal cell line (MRC-5) was evaluated.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Kratki izvodi radova - 55. Savetovanje Srpskog hemijskog društva, 8. i 9. juni 2018, Novi Sad / Book of abstracts - 55 Meeting of the Serbian Chemical Society, June 8-9, 2018, Novi Sad",
title = "Sinteza i in vitro antitumourska aktivnost novih mimetika goniofufurona sa tiofenskim prstenom na položaju C-7, Synthesis and in vitro antitumour activity of new goniofufurone mimics with  thiophene ring at the C-7 position",
pages = "82-82",
url = "https://hdl.handle.net/21.15107/rcub_cer_7095"
}

Popsavin, M., Kovačević, I., Kekezović, S., Svirčev, M., Srećo Zelenović, B., Kojić, V. V., Jadranin, M.,& Popsavin, V.. (2018). Sinteza i in vitro antitumourska aktivnost novih mimetika goniofufurona sa tiofenskim prstenom na položaju C-7. in Kratki izvodi radova - 55. Savetovanje Srpskog hemijskog društva, 8. i 9. juni 2018, Novi Sad / Book of abstracts - 55 Meeting of the Serbian Chemical Society, June 8-9, 2018, Novi Sad
Belgrade : Serbian Chemical Society., 82-82.
https://hdl.handle.net/21.15107/rcub_cer_7095

Popsavin M, Kovačević I, Kekezović S, Svirčev M, Srećo Zelenović B, Kojić VV, Jadranin M, Popsavin V. Sinteza i in vitro antitumourska aktivnost novih mimetika goniofufurona sa tiofenskim prstenom na položaju C-7. in Kratki izvodi radova - 55. Savetovanje Srpskog hemijskog društva, 8. i 9. juni 2018, Novi Sad / Book of abstracts - 55 Meeting of the Serbian Chemical Society, June 8-9, 2018, Novi Sad. 2018;:82-82.
https://hdl.handle.net/21.15107/rcub_cer_7095 .

Popsavin, Mirjana, Kovačević, Ivana, Kekezović, Slađana, Svirčev, Miloš, Srećo Zelenović, Bojana, Kojić, Vesna V., Jadranin, Milka, Popsavin, Velimir, "Sinteza i in vitro antitumourska aktivnost novih mimetika goniofufurona sa tiofenskim prstenom na položaju C-7" in Kratki izvodi radova - 55. Savetovanje Srpskog hemijskog društva, 8. i 9. juni 2018, Novi Sad / Book of abstracts - 55 Meeting of the Serbian Chemical Society, June 8-9, 2018, Novi Sad (2018):82-82,
https://hdl.handle.net/21.15107/rcub_cer_7095 .

TY  - CONF
AU  - Svirčev, Miloš
AU  - Popsavin, Mirjana
AU  - Kovačević, Ivana
AU  - Kojić, Vesna V.
AU  - Bogdanović, Gordana
AU  - Jadranin, Milka
AU  - Popsavin, Velimir
PY  - 2012
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7276
AB  - Herein we report a total synthesis of two novel goniofufurone and 7-epi-goniofufurone isosteres bearing a 2-thiazolyl-4-amide moiety instead of the phenyl group at C-7, as well as O-benzyl instead of hydroxyl group at C-5.
PB  - Wiley
C3  - 22nd International Symposium on Medicinal Chemistry, ISMC 2012, Berlin, Germany
T1  - Synthesis and Biological Activity of new 5-O-Benzyl-7-thiazolyl Isosteres of goniofufurone and 7-epi-goniofufurone
SP  - 342
EP  - 342
UR  - https://hdl.handle.net/21.15107/rcub_cer_7276
ER  - 

@conference{
author = "Svirčev, Miloš and Popsavin, Mirjana and Kovačević, Ivana and Kojić, Vesna V. and Bogdanović, Gordana and Jadranin, Milka and Popsavin, Velimir",
year = "2012",
abstract = "Herein we report a total synthesis of two novel goniofufurone and 7-epi-goniofufurone isosteres bearing a 2-thiazolyl-4-amide moiety instead of the phenyl group at C-7, as well as O-benzyl instead of hydroxyl group at C-5.",
publisher = "Wiley",
journal = "22nd International Symposium on Medicinal Chemistry, ISMC 2012, Berlin, Germany",
title = "Synthesis and Biological Activity of new 5-O-Benzyl-7-thiazolyl Isosteres of goniofufurone and 7-epi-goniofufurone",
pages = "342-342",
url = "https://hdl.handle.net/21.15107/rcub_cer_7276"
}

Svirčev, M., Popsavin, M., Kovačević, I., Kojić, V. V., Bogdanović, G., Jadranin, M.,& Popsavin, V.. (2012). Synthesis and Biological Activity of new 5-O-Benzyl-7-thiazolyl Isosteres of goniofufurone and 7-epi-goniofufurone. in 22nd International Symposium on Medicinal Chemistry, ISMC 2012, Berlin, Germany
Wiley., 342-342.
https://hdl.handle.net/21.15107/rcub_cer_7276

Svirčev M, Popsavin M, Kovačević I, Kojić VV, Bogdanović G, Jadranin M, Popsavin V. Synthesis and Biological Activity of new 5-O-Benzyl-7-thiazolyl Isosteres of goniofufurone and 7-epi-goniofufurone. in 22nd International Symposium on Medicinal Chemistry, ISMC 2012, Berlin, Germany. 2012;:342-342.
https://hdl.handle.net/21.15107/rcub_cer_7276 .

Svirčev, Miloš, Popsavin, Mirjana, Kovačević, Ivana, Kojić, Vesna V., Bogdanović, Gordana, Jadranin, Milka, Popsavin, Velimir, "Synthesis and Biological Activity of new 5-O-Benzyl-7-thiazolyl Isosteres of goniofufurone and 7-epi-goniofufurone" in 22nd International Symposium on Medicinal Chemistry, ISMC 2012, Berlin, Germany (2012):342-342,
https://hdl.handle.net/21.15107/rcub_cer_7276 .

TY  - CONF
AU  - Srećo, Bojana
AU  - Benedeković, Goran
AU  - Popsavin, Mirjana
AU  - Kojić, Vesna V.
AU  - Bogdanović, Gordana
AU  - Jadranin, Milka
AU  - Popsavin, Velimir
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7273
AB  - Herein we describe a modified total synthesis of (+)-Muricatacin starting from D-xylose, as well as synthesis of two new conformationally constrained (+)-muricatacin mimics from D-glucose.
PB  - IUPAC
C3  - The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway
T1  - Synthesis and antiprol iferative activity of (+)-muricatacin and two novel conformationally constrained analogues
SP  - 147
EP  - 147
UR  - https://hdl.handle.net/21.15107/rcub_cer_7273
ER  - 

@conference{
author = "Srećo, Bojana and Benedeković, Goran and Popsavin, Mirjana and Kojić, Vesna V. and Bogdanović, Gordana and Jadranin, Milka and Popsavin, Velimir",
year = "2010",
abstract = "Herein we describe a modified total synthesis of (+)-Muricatacin starting from D-xylose, as well as synthesis of two new conformationally constrained (+)-muricatacin mimics from D-glucose.",
publisher = "IUPAC",
journal = "The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway",
title = "Synthesis and antiprol iferative activity of (+)-muricatacin and two novel conformationally constrained analogues",
pages = "147-147",
url = "https://hdl.handle.net/21.15107/rcub_cer_7273"
}

Srećo, B., Benedeković, G., Popsavin, M., Kojić, V. V., Bogdanović, G., Jadranin, M.,& Popsavin, V.. (2010). Synthesis and antiprol iferative activity of (+)-muricatacin and two novel conformationally constrained analogues. in The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway
IUPAC., 147-147.
https://hdl.handle.net/21.15107/rcub_cer_7273

Srećo B, Benedeković G, Popsavin M, Kojić VV, Bogdanović G, Jadranin M, Popsavin V. Synthesis and antiprol iferative activity of (+)-muricatacin and two novel conformationally constrained analogues. in The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway. 2010;:147-147.
https://hdl.handle.net/21.15107/rcub_cer_7273 .

Srećo, Bojana, Benedeković, Goran, Popsavin, Mirjana, Kojić, Vesna V., Bogdanović, Gordana, Jadranin, Milka, Popsavin, Velimir, "Synthesis and antiprol iferative activity of (+)-muricatacin and two novel conformationally constrained analogues" in The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway (2010):147-147,
https://hdl.handle.net/21.15107/rcub_cer_7273 .

TY  - CONF
AU  - Svirčev, Miloš
AU  - Popsavin, Mirjana
AU  - Kojić, Vesna V.
AU  - Bogdanović, Gordana
AU  - Jadranin, Milka
AU  - Popsavin, Velimir
PY  - 2010
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7274
AB  - Herein we report a total synthesis of two novel (7-epi-)goniofufurone isosteres bearing a 2-thiazolyl-4-carboxylic acid ethyl ester moiety instead of the aromatic ring at C-7.
PB  - IUPAC
C3  - The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway
T1  - Synthesis and biological activity of new thiazole isosteres of goniofufurone and 7-epi-goniofufurone
SP  - 431
EP  - 431
UR  - https://hdl.handle.net/21.15107/rcub_cer_7274
ER  - 

@conference{
author = "Svirčev, Miloš and Popsavin, Mirjana and Kojić, Vesna V. and Bogdanović, Gordana and Jadranin, Milka and Popsavin, Velimir",
year = "2010",
abstract = "Herein we report a total synthesis of two novel (7-epi-)goniofufurone isosteres bearing a 2-thiazolyl-4-carboxylic acid ethyl ester moiety instead of the aromatic ring at C-7.",
publisher = "IUPAC",
journal = "The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway",
title = "Synthesis and biological activity of new thiazole isosteres of goniofufurone and 7-epi-goniofufurone",
pages = "431-431",
url = "https://hdl.handle.net/21.15107/rcub_cer_7274"
}

Svirčev, M., Popsavin, M., Kojić, V. V., Bogdanović, G., Jadranin, M.,& Popsavin, V.. (2010). Synthesis and biological activity of new thiazole isosteres of goniofufurone and 7-epi-goniofufurone. in The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway
IUPAC., 431-431.
https://hdl.handle.net/21.15107/rcub_cer_7274

Svirčev M, Popsavin M, Kojić VV, Bogdanović G, Jadranin M, Popsavin V. Synthesis and biological activity of new thiazole isosteres of goniofufurone and 7-epi-goniofufurone. in The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway. 2010;:431-431.
https://hdl.handle.net/21.15107/rcub_cer_7274 .

Svirčev, Miloš, Popsavin, Mirjana, Kojić, Vesna V., Bogdanović, Gordana, Jadranin, Milka, Popsavin, Velimir, "Synthesis and biological activity of new thiazole isosteres of goniofufurone and 7-epi-goniofufurone" in The 18th International Conference on Organic Synthesis, IUPAC ICOS-18, August 1-6 2010, Bergen, Norway (2010):431-431,
https://hdl.handle.net/21.15107/rcub_cer_7274 .