TY  - JOUR
AU  - Stanković Jeremić, Jovana
AU  - Gođevac, Dejan
AU  - Ivanović, Stefan
AU  - Simić, Katarina
AU  - Trendafilova, Antoaneta
AU  - Aćimović, Milica
AU  - Milosavljević, Slobodan
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5166
AB  - The application of High Performance Thin Layer Chromatography
(HPTLC)-based non-targeted metabolomics as a holistic approach to compare
fingerprints of metabolite changes during Artemisia annua development is
described. Images of HPTLC chromatograms obtained after derivatization with
anisaldehyde-sulphuric acid reagent were used as a dataset for multivariate
analysis. Principal component analysis and Orthogonal Partial Least Squares
Discriminant Analysis confirmed the discrimination of samples belonging to
vegetative phase, flowering stage, and seed formation stage of the plant
development. The obtained results showed that the HPTLC-based metabolomics
approach can be a very reliable technique for the investigation of metabolic
changes during plant development, complementary to GC-MS and NMR-based
metabolomics.
AB  - Описана је холистичка примена нетаргетне метаболомике базиране на високоефикасној танкослојној хроматографији (HPTLC) која омогућава поређење метаболичких профила Artemisia annua и праћење њихових промена током развоја биљке. HPTLC хроматограми након развијања анизалдехидом и сумпорном киселином су коришћени за генерисање података за мултиваријантну анализу. Анализа главних компоненти (PCA) и ортогонална дискриминанта анализа најмањих квадрата (OPLS-DA) су потврдиле разлике између узорака који припадају различитим фенофазама - вегетативној фази, фази цветања и фази формирања семена. Добијени резултати указују да метаболомички приступ заснован на HPTLC методи која је комплементарна са GC-MS и NMR анализом, може бити веома поуздана техника за анализу промене током развоја биљке.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - HPTLC-based metabolomics for the investigation of metabolic changes during plant development: The case study of Artemisia annua
T1  - Mетаболомикa базиранa на HPTLC за испитивање метаболичких промена током развоја биљке:  Artemisia annua студија случаја
VL  - 87
IS  - 11
SP  - 1237
EP  - 1244
DO  - 10.2298/JSC210507007S
ER  - 

@article{
author = "Stanković Jeremić, Jovana and Gođevac, Dejan and Ivanović, Stefan and Simić, Katarina and Trendafilova, Antoaneta and Aćimović, Milica and Milosavljević, Slobodan",
year = "2022",
abstract = "The application of High Performance Thin Layer Chromatography
(HPTLC)-based non-targeted metabolomics as a holistic approach to compare
fingerprints of metabolite changes during Artemisia annua development is
described. Images of HPTLC chromatograms obtained after derivatization with
anisaldehyde-sulphuric acid reagent were used as a dataset for multivariate
analysis. Principal component analysis and Orthogonal Partial Least Squares
Discriminant Analysis confirmed the discrimination of samples belonging to
vegetative phase, flowering stage, and seed formation stage of the plant
development. The obtained results showed that the HPTLC-based metabolomics
approach can be a very reliable technique for the investigation of metabolic
changes during plant development, complementary to GC-MS and NMR-based
metabolomics., Описана је холистичка примена нетаргетне метаболомике базиране на високоефикасној танкослојној хроматографији (HPTLC) која омогућава поређење метаболичких профила Artemisia annua и праћење њихових промена током развоја биљке. HPTLC хроматограми након развијања анизалдехидом и сумпорном киселином су коришћени за генерисање података за мултиваријантну анализу. Анализа главних компоненти (PCA) и ортогонална дискриминанта анализа најмањих квадрата (OPLS-DA) су потврдиле разлике између узорака који припадају различитим фенофазама - вегетативној фази, фази цветања и фази формирања семена. Добијени резултати указују да метаболомички приступ заснован на HPTLC методи која је комплементарна са GC-MS и NMR анализом, може бити веома поуздана техника за анализу промене током развоја биљке.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "HPTLC-based metabolomics for the investigation of metabolic changes during plant development: The case study of Artemisia annua, Mетаболомикa базиранa на HPTLC за испитивање метаболичких промена током развоја биљке:  Artemisia annua студија случаја",
volume = "87",
number = "11",
pages = "1237-1244",
doi = "10.2298/JSC210507007S"
}

Stanković Jeremić, J., Gođevac, D., Ivanović, S., Simić, K., Trendafilova, A., Aćimović, M.,& Milosavljević, S.. (2022). HPTLC-based metabolomics for the investigation of metabolic changes during plant development: The case study of Artemisia annua. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 87(11), 1237-1244.
https://doi.org/10.2298/JSC210507007S

Stanković Jeremić J, Gođevac D, Ivanović S, Simić K, Trendafilova A, Aćimović M, Milosavljević S. HPTLC-based metabolomics for the investigation of metabolic changes during plant development: The case study of Artemisia annua. in Journal of the Serbian Chemical Society. 2022;87(11):1237-1244.
doi:10.2298/JSC210507007S .

Stanković Jeremić, Jovana, Gođevac, Dejan, Ivanović, Stefan, Simić, Katarina, Trendafilova, Antoaneta, Aćimović, Milica, Milosavljević, Slobodan, "HPTLC-based metabolomics for the investigation of metabolic changes during plant development: The case study of Artemisia annua" in Journal of the Serbian Chemical Society, 87, no. 11 (2022):1237-1244,
https://doi.org/10.2298/JSC210507007S . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Lončar, Biljana
AU  - Pezo, Milada
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
AU  - Rat, Milica
AU  - Pezo, Lato
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5265
AB  - Unlike other studies that only determined the chemical composition of essential oils depending on their geographic origin, this research investigated the effect of weather conditions (temperature, precipitation, and insolation) on the chemical composition of Nepeta nuda L. essential oil. The collection of wild-growing N. nuda was carried out during three successive years, 2019, 2020, and 2021 at Rtanj Mountain (Serbia) on the same date (July 7th). Essential oil extraction from the plant was performed by hydro-distillation. After gas chromatographic-mass spectrometric analysis, a total of 102 volatile compounds were separated from N. nuda, during the observed period, 28 were unidentified, compromising between 5.0% and 8.7%, depending on the year. A multiple linear regression model was created, and statistical analyses were performed to provide knowledge about the prediction, feature profile, and the similarity in contents of active compounds of the N. nuda essential oil. The influence of temperature on the accumulation of the most abundant component, 1,8-cineole, was positive, while the impact of precipitation and insolation was negative. According to the cluster tree, there are four chemotypes of N. nuda essential oil: with nepetalactone, 1,8-cineole, mixed (nepetalactone+1,8-cineole+germacrene D), and nonspecific chemotypes. Bearing in mind that the biological activity of a raw material depends on the chemotype and environmental factors, this is a topic that deserves a more detailed approach. The N. nuda and its essential oil are promising materials with high biological potential, and these deserve further detailed investigation.
T2  - Horticulturae
T1  - Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia)
VL  - 8
IS  - 2
SP  - 85
DO  - 10.3390/horticulturae8020085
ER  - 

@article{
author = "Aćimović, Milica and Lončar, Biljana and Pezo, Milada and Stanković Jeremić, Jovana and Cvetković, Mirjana and Rat, Milica and Pezo, Lato",
year = "2022",
abstract = "Unlike other studies that only determined the chemical composition of essential oils depending on their geographic origin, this research investigated the effect of weather conditions (temperature, precipitation, and insolation) on the chemical composition of Nepeta nuda L. essential oil. The collection of wild-growing N. nuda was carried out during three successive years, 2019, 2020, and 2021 at Rtanj Mountain (Serbia) on the same date (July 7th). Essential oil extraction from the plant was performed by hydro-distillation. After gas chromatographic-mass spectrometric analysis, a total of 102 volatile compounds were separated from N. nuda, during the observed period, 28 were unidentified, compromising between 5.0% and 8.7%, depending on the year. A multiple linear regression model was created, and statistical analyses were performed to provide knowledge about the prediction, feature profile, and the similarity in contents of active compounds of the N. nuda essential oil. The influence of temperature on the accumulation of the most abundant component, 1,8-cineole, was positive, while the impact of precipitation and insolation was negative. According to the cluster tree, there are four chemotypes of N. nuda essential oil: with nepetalactone, 1,8-cineole, mixed (nepetalactone+1,8-cineole+germacrene D), and nonspecific chemotypes. Bearing in mind that the biological activity of a raw material depends on the chemotype and environmental factors, this is a topic that deserves a more detailed approach. The N. nuda and its essential oil are promising materials with high biological potential, and these deserve further detailed investigation.",
journal = "Horticulturae",
title = "Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia)",
volume = "8",
number = "2",
pages = "85",
doi = "10.3390/horticulturae8020085"
}

Aćimović, M., Lončar, B., Pezo, M., Stanković Jeremić, J., Cvetković, M., Rat, M.,& Pezo, L.. (2022). Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia). in Horticulturae, 8(2), 85.
https://doi.org/10.3390/horticulturae8020085

Aćimović M, Lončar B, Pezo M, Stanković Jeremić J, Cvetković M, Rat M, Pezo L. Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia). in Horticulturae. 2022;8(2):85.
doi:10.3390/horticulturae8020085 .

Aćimović, Milica, Lončar, Biljana, Pezo, Milada, Stanković Jeremić, Jovana, Cvetković, Mirjana, Rat, Milica, Pezo, Lato, "Volatile Compounds of Nepeta nuda L. from Rtanj Mountain (Serbia)" in Horticulturae, 8, no. 2 (2022):85,
https://doi.org/10.3390/horticulturae8020085 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Cvetković, Mirjana
AU  - Stanković Jeremić, Jovana
AU  - Pezo, Lato
AU  - Varga, Ana
AU  - Čabarkapa, Ivana
AU  - Kiprovski, Biljana
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5406
AB  - Salvia sclarea L. or clary sage is cultivated worldwide in temperate and sub-tropical climates, as an ornamental and essential oil (EO) bearing plant. EO is obtained from fresh spikes in full flowering stage and is recognized as an important commercial product for food, beverage and cosmetic industries. This study investigated the EO composition of S. sclarea grown in Serbia (Southeast Europe) obtained by two different methods, steam (SD) and hydrodistillation (HD). GC-MS analysis identified oxygenated monoterpenes as the main class of compounds for all EOs (between 81.8% and 88.2% depending on the distillation process). The most abundant oxygenated monoterpenes were linalyl acetate and linalool. In addition, in vitro antimicrobial (modified resazurin microtitre-plate assay) and antioxidant activities (DPPH• assay) and total polyphenol content of obtained EOs were also evaluated. According to the assay used for the evaluation of the antibacterial activity, Gram-negative bacteria were more sensitive to S. sclarea EO in comparison to Gram-positive bacteria. EOs exhibited low antioxidant capacity, below 3% neutralized DPPH• radicals, reaching up to approximately 400 µg AAE mL-1. This study also investigated a possibility for predicting retention indices (RIs) of compounds isolated from EOs. In total, 78 experimentally obtained RIs were applied to construct the prediction model. The quantitative structure-chromatographic retention relationship (QSRR) model was used to anticipate the experimentally obtained RIs. Five molecular descriptors were selected by factor analysis and genetic algorithm to predict RIs. The obtained accuracy of the QSRR model reached r2 =.912, which showed that these models might be applied for predicting retention indices.
PB  - Wiley
T2  - Flavour and Fragrance Journal
T1  - Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools
VL  - 37
IS  - 1
SP  - 20
EP  - 32
DO  - 10.1002/ffj.3684
ER  - 

@article{
author = "Aćimović, Milica and Cvetković, Mirjana and Stanković Jeremić, Jovana and Pezo, Lato and Varga, Ana and Čabarkapa, Ivana and Kiprovski, Biljana",
year = "2022",
abstract = "Salvia sclarea L. or clary sage is cultivated worldwide in temperate and sub-tropical climates, as an ornamental and essential oil (EO) bearing plant. EO is obtained from fresh spikes in full flowering stage and is recognized as an important commercial product for food, beverage and cosmetic industries. This study investigated the EO composition of S. sclarea grown in Serbia (Southeast Europe) obtained by two different methods, steam (SD) and hydrodistillation (HD). GC-MS analysis identified oxygenated monoterpenes as the main class of compounds for all EOs (between 81.8% and 88.2% depending on the distillation process). The most abundant oxygenated monoterpenes were linalyl acetate and linalool. In addition, in vitro antimicrobial (modified resazurin microtitre-plate assay) and antioxidant activities (DPPH• assay) and total polyphenol content of obtained EOs were also evaluated. According to the assay used for the evaluation of the antibacterial activity, Gram-negative bacteria were more sensitive to S. sclarea EO in comparison to Gram-positive bacteria. EOs exhibited low antioxidant capacity, below 3% neutralized DPPH• radicals, reaching up to approximately 400 µg AAE mL-1. This study also investigated a possibility for predicting retention indices (RIs) of compounds isolated from EOs. In total, 78 experimentally obtained RIs were applied to construct the prediction model. The quantitative structure-chromatographic retention relationship (QSRR) model was used to anticipate the experimentally obtained RIs. Five molecular descriptors were selected by factor analysis and genetic algorithm to predict RIs. The obtained accuracy of the QSRR model reached r2 =.912, which showed that these models might be applied for predicting retention indices.",
publisher = "Wiley",
journal = "Flavour and Fragrance Journal",
title = "Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools",
volume = "37",
number = "1",
pages = "20-32",
doi = "10.1002/ffj.3684"
}

Aćimović, M., Cvetković, M., Stanković Jeremić, J., Pezo, L., Varga, A., Čabarkapa, I.,& Kiprovski, B.. (2022). Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools. in Flavour and Fragrance Journal
Wiley., 37(1), 20-32.
https://doi.org/10.1002/ffj.3684

Aćimović M, Cvetković M, Stanković Jeremić J, Pezo L, Varga A, Čabarkapa I, Kiprovski B. Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools. in Flavour and Fragrance Journal. 2022;37(1):20-32.
doi:10.1002/ffj.3684 .

Aćimović, Milica, Cvetković, Mirjana, Stanković Jeremić, Jovana, Pezo, Lato, Varga, Ana, Čabarkapa, Ivana, Kiprovski, Biljana, "Biological activity and profiling of Salvia sclarea essential oil obtained by steam and hydrodistillation extraction methods via chemometrics tools" in Flavour and Fragrance Journal, 37, no. 1 (2022):20-32,
https://doi.org/10.1002/ffj.3684 . .

TY  - CONF
AU  - Anđelković, Boban
AU  - Gođevac, Dejan
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Tešević, Vele
AU  - Milosavljević, Slobodan
AU  - Simić, Katarina
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5526
AB  - A large number of plant metabolites has provided an incomparable chemical source of the pharmaceutical
products. The two major fields of chemical research on biological active small molecules, metabolomics and
natural product discovery, have the similar goals of identifying and characterizing small molecules, either in
their isolated active state (natural product chemistry). Metabolomics generate a profile of small molecules
from plant extracts, which could be directly responsible for bioactivity effects. Using dry-column flash
chromatography enable a rapid and inexpensive method for the very efficient separation of plant extract with
a high resolution. This separation method coupled to NMR and FTIR-based metabolomics is applied to identify
bioactive natural products. OPLS multivariate analysis method, was used for correlation the chemical
composition of the plant extracts, Amphoricarpos autariatus, with the results of cytotoxic activity against
Human cervical adenocarcinoma cell line (HeLa) and epithelial lung cancer cell line (A549). In this way, the
highest contribution to the cytotoxic activity was recorded for the guaianolide sesquiterpene lactone were
tested, and their cytotoxic activity were conformed.
PB  - Portugal : PROTEOMASS Scientific Society
C3  - Book of abstracts - 5th International Caparica Christmas Conference  on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal
T1  - Integration	of	dry-column	flash	chromatography	with	NMR	 and	 FTIR	 metabolomics	 to	 reveal	 cytotoxic	 metabolites	 from	 Amphoricarpos	autariatus
SP  - 148
EP  - 148
UR  - https://hdl.handle.net/21.15107/rcub_cer_5526
ER  - 

@conference{
author = "Anđelković, Boban and Gođevac, Dejan and Stanković, Jovana and Cvetković, Mirjana and Tešević, Vele and Milosavljević, Slobodan and Simić, Katarina",
year = "2021",
abstract = "A large number of plant metabolites has provided an incomparable chemical source of the pharmaceutical
products. The two major fields of chemical research on biological active small molecules, metabolomics and
natural product discovery, have the similar goals of identifying and characterizing small molecules, either in
their isolated active state (natural product chemistry). Metabolomics generate a profile of small molecules
from plant extracts, which could be directly responsible for bioactivity effects. Using dry-column flash
chromatography enable a rapid and inexpensive method for the very efficient separation of plant extract with
a high resolution. This separation method coupled to NMR and FTIR-based metabolomics is applied to identify
bioactive natural products. OPLS multivariate analysis method, was used for correlation the chemical
composition of the plant extracts, Amphoricarpos autariatus, with the results of cytotoxic activity against
Human cervical adenocarcinoma cell line (HeLa) and epithelial lung cancer cell line (A549). In this way, the
highest contribution to the cytotoxic activity was recorded for the guaianolide sesquiterpene lactone were
tested, and their cytotoxic activity were conformed.",
publisher = "Portugal : PROTEOMASS Scientific Society",
journal = "Book of abstracts - 5th International Caparica Christmas Conference  on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal",
title = "Integration	of	dry-column	flash	chromatography	with	NMR	 and	 FTIR	 metabolomics	 to	 reveal	 cytotoxic	 metabolites	 from	 Amphoricarpos	autariatus",
pages = "148-148",
url = "https://hdl.handle.net/21.15107/rcub_cer_5526"
}

Anđelković, B., Gođevac, D., Stanković, J., Cvetković, M., Tešević, V., Milosavljević, S.,& Simić, K.. (2021). Integration	of	dry-column	flash	chromatography	with	NMR	 and	 FTIR	 metabolomics	 to	 reveal	 cytotoxic	 metabolites	 from	 Amphoricarpos	autariatus. in Book of abstracts - 5th International Caparica Christmas Conference  on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal
Portugal : PROTEOMASS Scientific Society., 148-148.
https://hdl.handle.net/21.15107/rcub_cer_5526

Anđelković B, Gođevac D, Stanković J, Cvetković M, Tešević V, Milosavljević S, Simić K. Integration	of	dry-column	flash	chromatography	with	NMR	 and	 FTIR	 metabolomics	 to	 reveal	 cytotoxic	 metabolites	 from	 Amphoricarpos	autariatus. in Book of abstracts - 5th International Caparica Christmas Conference  on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal. 2021;:148-148.
https://hdl.handle.net/21.15107/rcub_cer_5526 .

Anđelković, Boban, Gođevac, Dejan, Stanković, Jovana, Cvetković, Mirjana, Tešević, Vele, Milosavljević, Slobodan, Simić, Katarina, "Integration	of	dry-column	flash	chromatography	with	NMR	 and	 FTIR	 metabolomics	 to	 reveal	 cytotoxic	 metabolites	 from	 Amphoricarpos	autariatus" in Book of abstracts - 5th International Caparica Christmas Conference  on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal (2021):148-148,
https://hdl.handle.net/21.15107/rcub_cer_5526 .

TY  - JOUR
AU  - Stupar, Sofija
AU  - Dragićević, Milan B.
AU  - Tešević, Vele
AU  - Stanković Jeremić, Jovana
AU  - Maksimović, Vuk
AU  - Ćosić, Tatjana
AU  - Devrnja, Nina
AU  - Tubić, Ljiljana
AU  - Cingel, Aleksandar
AU  - Vinterhalter, Branka
AU  - Ninković, Slavica
AU  - Savić, Jelena M.
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4241
AB  - Flower strips of French Marigold are commonly used pest repellents in potato fields. However, the effect of French Marigold volatiles on potato metabolism, physiology and induced defense is unknown. Thus, a microarray transcriptome analysis was performed to study the effects of French Marigold essential oil (EO) on laboratory-grown potato. After 8 h of exposure to EO, with gas chromatography/mass spectrometry (GC/MS)-detected terpinolene and limonene as dominant compounds, 2796 transcripts were differentially expressed with fold change >2 compared to expression in controls. A slightly higher number of transcripts had suppressed expression (1493 down-vs. 1303 up-regulated). Since transcripts, annotated to different photosynthesis-related processes, were mostly down-regulated, we selected a set of 10 genes involved in the leaf starch metabolism pathway, and validated microarray patterns using quantitative reverse transcription polymerase chain reaction (RT-qPCR). Except for decreased synthesis and induced decomposition of starch granule in leaves, 8 h long EO exposure slightly elevated the accumulation of sucrose compared to glucose and fructose in subjected potato plants. An in vitro feeding bioassay with Colorado potato beetle showed that EO-induced alternations on transcriptional level and in the sugars’ metabolism caused the enhancement of feeding behavior and overall development of the tested larvae. Results of comprehensive analysis of transcriptional responses in potato exposed to French Marigold EO provide a basis for further elucidation of molecular mechanisms underlying eco-physiological interactions in companion planting cropping systems.
PB  - MDPI
T2  - Plants
T1  - Transcriptome profiling of the potato exposed to french marigold essential oil with a special emphasis on leaf starch metabolism and defense against colorado potato beetle
VL  - 10
IS  - 1
SP  - 172
DO  - 10.3390/plants10010172
ER  - 

@article{
author = "Stupar, Sofija and Dragićević, Milan B. and Tešević, Vele and Stanković Jeremić, Jovana and Maksimović, Vuk and Ćosić, Tatjana and Devrnja, Nina and Tubić, Ljiljana and Cingel, Aleksandar and Vinterhalter, Branka and Ninković, Slavica and Savić, Jelena M.",
year = "2021",
abstract = "Flower strips of French Marigold are commonly used pest repellents in potato fields. However, the effect of French Marigold volatiles on potato metabolism, physiology and induced defense is unknown. Thus, a microarray transcriptome analysis was performed to study the effects of French Marigold essential oil (EO) on laboratory-grown potato. After 8 h of exposure to EO, with gas chromatography/mass spectrometry (GC/MS)-detected terpinolene and limonene as dominant compounds, 2796 transcripts were differentially expressed with fold change >2 compared to expression in controls. A slightly higher number of transcripts had suppressed expression (1493 down-vs. 1303 up-regulated). Since transcripts, annotated to different photosynthesis-related processes, were mostly down-regulated, we selected a set of 10 genes involved in the leaf starch metabolism pathway, and validated microarray patterns using quantitative reverse transcription polymerase chain reaction (RT-qPCR). Except for decreased synthesis and induced decomposition of starch granule in leaves, 8 h long EO exposure slightly elevated the accumulation of sucrose compared to glucose and fructose in subjected potato plants. An in vitro feeding bioassay with Colorado potato beetle showed that EO-induced alternations on transcriptional level and in the sugars’ metabolism caused the enhancement of feeding behavior and overall development of the tested larvae. Results of comprehensive analysis of transcriptional responses in potato exposed to French Marigold EO provide a basis for further elucidation of molecular mechanisms underlying eco-physiological interactions in companion planting cropping systems.",
publisher = "MDPI",
journal = "Plants",
title = "Transcriptome profiling of the potato exposed to french marigold essential oil with a special emphasis on leaf starch metabolism and defense against colorado potato beetle",
volume = "10",
number = "1",
pages = "172",
doi = "10.3390/plants10010172"
}

Stupar, S., Dragićević, M. B., Tešević, V., Stanković Jeremić, J., Maksimović, V., Ćosić, T., Devrnja, N., Tubić, L., Cingel, A., Vinterhalter, B., Ninković, S.,& Savić, J. M.. (2021). Transcriptome profiling of the potato exposed to french marigold essential oil with a special emphasis on leaf starch metabolism and defense against colorado potato beetle. in Plants
MDPI., 10(1), 172.
https://doi.org/10.3390/plants10010172

Stupar S, Dragićević MB, Tešević V, Stanković Jeremić J, Maksimović V, Ćosić T, Devrnja N, Tubić L, Cingel A, Vinterhalter B, Ninković S, Savić JM. Transcriptome profiling of the potato exposed to french marigold essential oil with a special emphasis on leaf starch metabolism and defense against colorado potato beetle. in Plants. 2021;10(1):172.
doi:10.3390/plants10010172 .

Stupar, Sofija, Dragićević, Milan B., Tešević, Vele, Stanković Jeremić, Jovana, Maksimović, Vuk, Ćosić, Tatjana, Devrnja, Nina, Tubić, Ljiljana, Cingel, Aleksandar, Vinterhalter, Branka, Ninković, Slavica, Savić, Jelena M., "Transcriptome profiling of the potato exposed to french marigold essential oil with a special emphasis on leaf starch metabolism and defense against colorado potato beetle" in Plants, 10, no. 1 (2021):172,
https://doi.org/10.3390/plants10010172 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Lončar, Biljana
AU  - Kiprovski, Biljana
AU  - Stanković Jeremić, Jovana
AU  - Todosijević, Marina
AU  - Pezo, Lato
AU  - Jeremić, Jelena
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4785
AB  - Ecological conditions of the growing areas, growing practices as well as harvest and postharvest processing influence the yield and quality of chamomile. The aim of this research was to determine the influence of chamomile separation methods, as postharvest treatments, on the essential oil quality and content, with a view to improve current primary processing of this valuable medicinal plant. In order to explain the structure of laboratory data that would give deeper assessment of similarities among various samples of chamomile essential oil, PCA was employed. Tested results showed that separation of chamomile plant material, as postharvest and pre-drying treatment, had significant influence on the number of identified compounds in the chamomile essential oil. The highest content of individual essential oil compounds had chamomile flowers with short stems, especially α-bisabolol, chamazulene, Z-spiroether and E-β-farnesene. In the essential oil obtained from chamomile flowers with long stems, content of α-bisabolol and chamazulene were significantly lower, while E-β-farnesene and Z-spiroether contents were significantly higher. Furthermore, in the essential oil obtained from chamomile plant material without separation, the lowest content of αbisabolol and Z-spiroether, and the highest content of E-β-farnesene were recorded. The correlation analysis was performed to investigate the likeness in the amounts of the active compounds of essential oil from differently processed chamomile samples. All these results indicate the importance of precise and controlled postharvest treatments, since it clearly affects the essential oil quality and content in the primary processing of this valuable medicinal plant.
AB  - Ekološki uslovi proizvodnog područja, tehnologija gajenja kao i žetva, ali i posležetveni tretmani značajno utiču na prinos i kvalitet kamilice. Cilj ovog istraživanja je bio da se odredi uticaj metoda separacije, kao posležetvenog tretmana, na kvalitet etarskog ulja, sa ciljem da se unapredi process primarne prerade ove lekovite biljke. Da bi se objasnila struktura laboratorijskih podataka, procenile i sagledale sličnosti i razlike između uzoraka etarskih ulja kamilice dobijenih primenom različitih metoda separacije, korišćena je PCA metoda. Dobijeni rezultati pokazuju da separacija sirovine kamilice kao posležetveni tretman koji prethodi sušenju, ima značajnog uticaja na broj identifikovanih komponenti u etarskom ulju, ali i njihov udeo. Najmanji broj pojedinačnih komponenti u etarskom ulju je imao uzorak cvetnih glavica sa kratkom drškom, pri čemu je zabeležen najveći sadržaj α-bisabolol, hamazulen, Z-spiroeter i E-β-farnesen. U etarskom ulju dobijenom od biljne sirovine sa većim udelom stabla kamilice, sadržaj α-bisabolola i hamazulena je bio značajno niži, dok je sadržaj E-β-farnesena i Z-spiroetera bio značajno viši. Dalje, u etarskom ulju dobijenom od bioljnog materijala bez separacije, zabeležen je najniži sadržaj α-bisabolola i Z-spiroetera, i najveći sadržaj E-β-farnesena. Analiza korelacije je izvedena da bi se ispitala sličnost u sadržaju aktivnih komponenti u etarskom ulju dobijenom primenom različitih procesa separacije kamilice. Svi rezultati ukazuju na značaj primene posležetvenih tretmana, jer se jasno vidi njihov uticaj na kvalitet etarskog ulja ove veoma važne lekovite biljke.
PB  - Novi Sad : Institut za ratarstvo i povrtarstvo
T2  - Ratarstvo i Povrtarstvo
T1  - Chamomile essential oil quality after postharvest separation treatments
T1  - Uticaj tretmana poslezetvene separacije na kvalitet etarskog ulja kamilice
VL  - 58
VL  - 2
SP  - 72
EP  - 78
DO  - 10.5937/RATPOV58-33346
ER  - 

@article{
author = "Aćimović, Milica and Lončar, Biljana and Kiprovski, Biljana and Stanković Jeremić, Jovana and Todosijević, Marina and Pezo, Lato and Jeremić, Jelena",
year = "2021",
abstract = "Ecological conditions of the growing areas, growing practices as well as harvest and postharvest processing influence the yield and quality of chamomile. The aim of this research was to determine the influence of chamomile separation methods, as postharvest treatments, on the essential oil quality and content, with a view to improve current primary processing of this valuable medicinal plant. In order to explain the structure of laboratory data that would give deeper assessment of similarities among various samples of chamomile essential oil, PCA was employed. Tested results showed that separation of chamomile plant material, as postharvest and pre-drying treatment, had significant influence on the number of identified compounds in the chamomile essential oil. The highest content of individual essential oil compounds had chamomile flowers with short stems, especially α-bisabolol, chamazulene, Z-spiroether and E-β-farnesene. In the essential oil obtained from chamomile flowers with long stems, content of α-bisabolol and chamazulene were significantly lower, while E-β-farnesene and Z-spiroether contents were significantly higher. Furthermore, in the essential oil obtained from chamomile plant material without separation, the lowest content of αbisabolol and Z-spiroether, and the highest content of E-β-farnesene were recorded. The correlation analysis was performed to investigate the likeness in the amounts of the active compounds of essential oil from differently processed chamomile samples. All these results indicate the importance of precise and controlled postharvest treatments, since it clearly affects the essential oil quality and content in the primary processing of this valuable medicinal plant., Ekološki uslovi proizvodnog područja, tehnologija gajenja kao i žetva, ali i posležetveni tretmani značajno utiču na prinos i kvalitet kamilice. Cilj ovog istraživanja je bio da se odredi uticaj metoda separacije, kao posležetvenog tretmana, na kvalitet etarskog ulja, sa ciljem da se unapredi process primarne prerade ove lekovite biljke. Da bi se objasnila struktura laboratorijskih podataka, procenile i sagledale sličnosti i razlike između uzoraka etarskih ulja kamilice dobijenih primenom različitih metoda separacije, korišćena je PCA metoda. Dobijeni rezultati pokazuju da separacija sirovine kamilice kao posležetveni tretman koji prethodi sušenju, ima značajnog uticaja na broj identifikovanih komponenti u etarskom ulju, ali i njihov udeo. Najmanji broj pojedinačnih komponenti u etarskom ulju je imao uzorak cvetnih glavica sa kratkom drškom, pri čemu je zabeležen najveći sadržaj α-bisabolol, hamazulen, Z-spiroeter i E-β-farnesen. U etarskom ulju dobijenom od biljne sirovine sa većim udelom stabla kamilice, sadržaj α-bisabolola i hamazulena je bio značajno niži, dok je sadržaj E-β-farnesena i Z-spiroetera bio značajno viši. Dalje, u etarskom ulju dobijenom od bioljnog materijala bez separacije, zabeležen je najniži sadržaj α-bisabolola i Z-spiroetera, i najveći sadržaj E-β-farnesena. Analiza korelacije je izvedena da bi se ispitala sličnost u sadržaju aktivnih komponenti u etarskom ulju dobijenom primenom različitih procesa separacije kamilice. Svi rezultati ukazuju na značaj primene posležetvenih tretmana, jer se jasno vidi njihov uticaj na kvalitet etarskog ulja ove veoma važne lekovite biljke.",
publisher = "Novi Sad : Institut za ratarstvo i povrtarstvo",
journal = "Ratarstvo i Povrtarstvo",
title = "Chamomile essential oil quality after postharvest separation treatments, Uticaj tretmana poslezetvene separacije na kvalitet etarskog ulja kamilice",
volume = "58, 2",
pages = "72-78",
doi = "10.5937/RATPOV58-33346"
}

Aćimović, M., Lončar, B., Kiprovski, B., Stanković Jeremić, J., Todosijević, M., Pezo, L.,& Jeremić, J.. (2021). Chamomile essential oil quality after postharvest separation treatments. in Ratarstvo i Povrtarstvo
Novi Sad : Institut za ratarstvo i povrtarstvo., 58, 72-78.
https://doi.org/10.5937/RATPOV58-33346

Aćimović M, Lončar B, Kiprovski B, Stanković Jeremić J, Todosijević M, Pezo L, Jeremić J. Chamomile essential oil quality after postharvest separation treatments. in Ratarstvo i Povrtarstvo. 2021;58:72-78.
doi:10.5937/RATPOV58-33346 .

Aćimović, Milica, Lončar, Biljana, Kiprovski, Biljana, Stanković Jeremić, Jovana, Todosijević, Marina, Pezo, Lato, Jeremić, Jelena, "Chamomile essential oil quality after postharvest separation treatments" in Ratarstvo i Povrtarstvo, 58 (2021):72-78,
https://doi.org/10.5937/RATPOV58-33346 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Zeremski, Tijana
AU  - Lončar, Biljana
AU  - Marjanović  Jeromela, Ana
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
AU  - Sikora, Vladimir
AU  - Ignjatov, Maja
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4829
AB  - This paper is a study of the chemical composition of Hyssopus officinalis ssp. Officinalis grown during three years (2017-2019) at the Institute of Field and Vegetable Crops Novi Sad (Vojvodina Province, Serbia). Furthermore, comparisons with ISO standards during the years were also investigated, as well as a prediction model of retention indices of compounds from the essential oils. An essential oil obtained by hydrodistillation and analysed by GC-FID and GC-MS was isopinocamphone chemotype. The gathered information about the volatile compounds from H. officinalis was used to classify the samples using the unrooted cluster tree. The correlation analysis was applied to investigate the similarity of different samples, according to GC-MS data. The quantitative structure- retention relationship (QSRR) was also employed to predict the retention indices of the identified compounds. A total of 74 experimentally obtained retention indices were used to build a prediction model. The coefficient of determination for the training cycle was 0.910, indicating that this model could be used for the prediction of retention indices for H. officinalis essential oil compounds.
PB  - MDPI
T2  - Processes
T1  - Weather conditions influence on hyssop essential oil quality
VL  - 9
IS  - 7
SP  - 1152
DO  - 10.3390/pr9071152
ER  - 

@article{
author = "Aćimović, Milica and Pezo, Lato and Zeremski, Tijana and Lončar, Biljana and Marjanović  Jeromela, Ana and Stanković Jeremić, Jovana and Cvetković, Mirjana and Sikora, Vladimir and Ignjatov, Maja",
year = "2021",
abstract = "This paper is a study of the chemical composition of Hyssopus officinalis ssp. Officinalis grown during three years (2017-2019) at the Institute of Field and Vegetable Crops Novi Sad (Vojvodina Province, Serbia). Furthermore, comparisons with ISO standards during the years were also investigated, as well as a prediction model of retention indices of compounds from the essential oils. An essential oil obtained by hydrodistillation and analysed by GC-FID and GC-MS was isopinocamphone chemotype. The gathered information about the volatile compounds from H. officinalis was used to classify the samples using the unrooted cluster tree. The correlation analysis was applied to investigate the similarity of different samples, according to GC-MS data. The quantitative structure- retention relationship (QSRR) was also employed to predict the retention indices of the identified compounds. A total of 74 experimentally obtained retention indices were used to build a prediction model. The coefficient of determination for the training cycle was 0.910, indicating that this model could be used for the prediction of retention indices for H. officinalis essential oil compounds.",
publisher = "MDPI",
journal = "Processes",
title = "Weather conditions influence on hyssop essential oil quality",
volume = "9",
number = "7",
pages = "1152",
doi = "10.3390/pr9071152"
}

Aćimović, M., Pezo, L., Zeremski, T., Lončar, B., Marjanović  Jeromela, A., Stanković Jeremić, J., Cvetković, M., Sikora, V.,& Ignjatov, M.. (2021). Weather conditions influence on hyssop essential oil quality. in Processes
MDPI., 9(7), 1152.
https://doi.org/10.3390/pr9071152

Aćimović M, Pezo L, Zeremski T, Lončar B, Marjanović  Jeromela A, Stanković Jeremić J, Cvetković M, Sikora V, Ignjatov M. Weather conditions influence on hyssop essential oil quality. in Processes. 2021;9(7):1152.
doi:10.3390/pr9071152 .

Aćimović, Milica, Pezo, Lato, Zeremski, Tijana, Lončar, Biljana, Marjanović  Jeromela, Ana, Stanković Jeremić, Jovana, Cvetković, Mirjana, Sikora, Vladimir, Ignjatov, Maja, "Weather conditions influence on hyssop essential oil quality" in Processes, 9, no. 7 (2021):1152,
https://doi.org/10.3390/pr9071152 . .

TY  - JOUR
AU  - Sofrenić, Ivana
AU  - Ljujić, Jovana
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Stanković Jeremić, Jovana
AU  - Ćirić, Ana
AU  - Soković, Marina
AU  - Andjelković, Boban
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4909
AB  - The objective of this study was to test four-dimensional LC-ESI-MS/MS chromatography in analysis of complex mixture such as ethanol extracts of different propolis samples. In total more than 1200 picks were identified and only for 185 literature conformation was found. The given data represent the result of tentative identification, and summarized results are given in the text. Comparing the samples, from different altitudes, 96 components were detected as characteristic in high altitude samples and 18 in samples collected at low altitudes. Antimicrobial activity of ethanol extracts of propolis (EEP) and pro­pyl­ene glycol extracts of propolis (PGEP) were carried out on S. aureus, B. cereus, M. flavus, L. monocytogenes, P. aeruginosa, S. typhimurium, E. coli and E. cloacae bacterial strains and compared with broad-spectrum antibiotics, streptomycin and ampicillin. Anti-quorum sensing activity was performed on P. aeruginosa by testing the effect of representative propolis extracts on bio­film formation, twitching and motility activity and production of pyocyanin. We demonstrated that the majority of explored propolis extracts have greater or equal minimal inhibitory concentration and minimum bactericidal concen­tra­tion values compared to antibiotics, independently of the solvent used for the extraction. The samples collected from the highest altitude emerged as least active antimicrobial agents but with the greatest potential as anti-quorum sen­sing agents.
AB  - Циљ овог истраживања је билo тестирање четвородимензионалне LC–ESI-MS/MS хроматографије у анализи комплексних смеша, као што су етанолни екстракти различитих узорака прополиса. Укупно је идентификовано више од 1200 пикова, а самo за 185 смо нашли литературну потврду. Приказани подаци представљају тентативну идентификацију и сумирани резултат је дат у тексту. Поређењем узорака са различитих надморских висина, за 96 једињења је утврђено да се налазе само у узорцима са високе надморске висине и 18 само у узорцима прикупљеним на нижим надморским висинама. Антибактеријске активности етанолних и пропиленгликолних екстрактата прополиса (EEP и PGEP, редом) тестиране су на S. aureus, B. cereus, M. flavus, L. monocytogenes, P. aeruginosa, S. typhimurium, E. coli и E. cloacae бактеријским линијама и поређене са анти- биотицима широког спектра деловања, стрептомицином и ампицилином. Anti-quorum sensing активност је тестирана на P. aeruginosa испитивањем ефекта репрезентативних екстраката прополиса на формирање биофилма, тестовима покретљивости руба коло- није (twitching и mobility) и производње пиоцианина. Показали смо да највећи број, коришћених екстраката прополиса, има истe и/или мање MIC и MBC вредности, у поре- ђењу са атибиотицима, независно од растварача коришћеног за екстракцију. Узорци прикупљени на високим надморским висинама су се показали као најмање активни антибактерициди али имају велики anti-quorum sensing потенцијал.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Application of LC-MS/MS with ion mobility for chemical analysis of propolis extracts with antimicrobial potential
T1  - Примена lc–ms/ms технике са јонском покретљивошћу за хемијску анализу екстраката прополиса са антимикробним потенцијалом.
IS  - 12
SP  - 1205
EP  - 1218
DO  - 10.2298/JSC210812086S
ER  - 

@article{
author = "Sofrenić, Ivana and Ljujić, Jovana and Simić, Katarina and Ivanović, Stefan and Stanković Jeremić, Jovana and Ćirić, Ana and Soković, Marina and Andjelković, Boban",
year = "2021",
abstract = "The objective of this study was to test four-dimensional LC-ESI-MS/MS chromatography in analysis of complex mixture such as ethanol extracts of different propolis samples. In total more than 1200 picks were identified and only for 185 literature conformation was found. The given data represent the result of tentative identification, and summarized results are given in the text. Comparing the samples, from different altitudes, 96 components were detected as characteristic in high altitude samples and 18 in samples collected at low altitudes. Antimicrobial activity of ethanol extracts of propolis (EEP) and pro­pyl­ene glycol extracts of propolis (PGEP) were carried out on S. aureus, B. cereus, M. flavus, L. monocytogenes, P. aeruginosa, S. typhimurium, E. coli and E. cloacae bacterial strains and compared with broad-spectrum antibiotics, streptomycin and ampicillin. Anti-quorum sensing activity was performed on P. aeruginosa by testing the effect of representative propolis extracts on bio­film formation, twitching and motility activity and production of pyocyanin. We demonstrated that the majority of explored propolis extracts have greater or equal minimal inhibitory concentration and minimum bactericidal concen­tra­tion values compared to antibiotics, independently of the solvent used for the extraction. The samples collected from the highest altitude emerged as least active antimicrobial agents but with the greatest potential as anti-quorum sen­sing agents., Циљ овог истраживања је билo тестирање четвородимензионалне LC–ESI-MS/MS хроматографије у анализи комплексних смеша, као што су етанолни екстракти различитих узорака прополиса. Укупно је идентификовано више од 1200 пикова, а самo за 185 смо нашли литературну потврду. Приказани подаци представљају тентативну идентификацију и сумирани резултат је дат у тексту. Поређењем узорака са различитих надморских висина, за 96 једињења је утврђено да се налазе само у узорцима са високе надморске висине и 18 само у узорцима прикупљеним на нижим надморским висинама. Антибактеријске активности етанолних и пропиленгликолних екстрактата прополиса (EEP и PGEP, редом) тестиране су на S. aureus, B. cereus, M. flavus, L. monocytogenes, P. aeruginosa, S. typhimurium, E. coli и E. cloacae бактеријским линијама и поређене са анти- биотицима широког спектра деловања, стрептомицином и ампицилином. Anti-quorum sensing активност је тестирана на P. aeruginosa испитивањем ефекта репрезентативних екстраката прополиса на формирање биофилма, тестовима покретљивости руба коло- није (twitching и mobility) и производње пиоцианина. Показали смо да највећи број, коришћених екстраката прополиса, има истe и/или мање MIC и MBC вредности, у поре- ђењу са атибиотицима, независно од растварача коришћеног за екстракцију. Узорци прикупљени на високим надморским висинама су се показали као најмање активни антибактерициди али имају велики anti-quorum sensing потенцијал.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Application of LC-MS/MS with ion mobility for chemical analysis of propolis extracts with antimicrobial potential, Примена lc–ms/ms технике са јонском покретљивошћу за хемијску анализу екстраката прополиса са антимикробним потенцијалом.",
number = "12",
pages = "1205-1218",
doi = "10.2298/JSC210812086S"
}

Sofrenić, I., Ljujić, J., Simić, K., Ivanović, S., Stanković Jeremić, J., Ćirić, A., Soković, M.,& Andjelković, B.. (2021). Application of LC-MS/MS with ion mobility for chemical analysis of propolis extracts with antimicrobial potential. in Journal of the Serbian Chemical Society
Serbian Chemical Society.(12), 1205-1218.
https://doi.org/10.2298/JSC210812086S

Sofrenić I, Ljujić J, Simić K, Ivanović S, Stanković Jeremić J, Ćirić A, Soković M, Andjelković B. Application of LC-MS/MS with ion mobility for chemical analysis of propolis extracts with antimicrobial potential. in Journal of the Serbian Chemical Society. 2021;(12):1205-1218.
doi:10.2298/JSC210812086S .

Sofrenić, Ivana, Ljujić, Jovana, Simić, Katarina, Ivanović, Stefan, Stanković Jeremić, Jovana, Ćirić, Ana, Soković, Marina, Andjelković, Boban, "Application of LC-MS/MS with ion mobility for chemical analysis of propolis extracts with antimicrobial potential" in Journal of the Serbian Chemical Society, no. 12 (2021):1205-1218,
https://doi.org/10.2298/JSC210812086S . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Stanković Jeremić, Jovana
AU  - Simić, Katarina
AU  - Ivanović, Stefan
AU  - Ljujić, Jovana
AU  - Čabarkapa, Ivana
AU  - Radojčin, Milivoj
AU  - Todosijević, Marina
AU  - Cvetković, Mirjana
PY  - 2021
UR  - http://letopisnaucnihradova.rs/wp-content/uploads/2021/09/Essential_oil_quality_of_chamomile_grown_in_Province_of_Vojvodina-Acimovic_et_al..pdf
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5167
AB  - Chamomile (Matricaria chamomilla L., Asteraceae) is one of the most popular medicinal plants used as a herb
infusion for treating numerous ailments, including sleep disorders, anxiety, digestion and intestinal conditions
etc. Chamomile essential oil is used in a wide variety of consumer goods such as detergents, soaps, toiletries,
cosmetics, pharmaceuticals, perfumes, confectionery food products, soft drinks, distilled alcoholic beverages
(hard liquor) and as insecticide. According to the European Pharmacopoeia, there are two types of essential
oils, one rich in bisabolol oxides and the other in α-bisabolol, which are preferred for tea brewing because of
its sweet, grassy, and slightly fruity aroma. From the other side, varieties rich in chamazulene and β-farnesene
have bitter taste, and because of that they are low valuable raw material. According to the results of the
essential oil composition obtained from three different chamomile samples grown in Province of Vojvodina, it
could be concluded that domestic cultivars “Banatska” and “Tetraploidna” contains β-farnesene as dominant
compound, while the content of bisabolol oxides and α-bisabolol was lower than required standards in
European Pharmacopoeia. Because of that they could not be classified as quality raw material. The German
cultivar “Mabamille” grown in agroecological conditions of Vojvodina region, with 37.5% of α-bisabolol can be
classified as a bisabolol rich type, and as high quality row material.
AB  - Kamilica (Matricaria chamomilla L., Asteraceae) je jedna od najpopularnijih lekovitih biljaka koja se 
upotrebljava u obliku infuza (čaja) za lečenje mnogih stanja i bolesti, uključujući poremećaje sna, napetost, probleme organa za varenje itd. Etarsko ulje kamilice se koristi u mnogim granama industrije: hemijskoj (kao dodatak deterdžentima), kozmetičkoj (u sapunima, sredstvima za ličnu higijenu), farmaceutskoj, parfimerijskoj i prehrambenoj industriji (u slatkišima, alkoholnim i bezalkoholnim pićima) i kao insekticid. Prema Evropskoj Farmakopeji, postoje dva tipa etarskog ulja kamilice, prvi koji je bogat bisabolol oksidima i drugi bogat α-bisabololom. Oba tipa su poželjna u industriji čajnih napitaka zbog njihovog slatkog, osvežavajućeg ukusa blago voćne arome. Sa druge strane, varijeteti bogati hamazulenom i β-farnezenom imaju gorak ukus i zbog toga predstavljaju manje vrednu biljnu sirovinu. Na osnovu rezultata hemijskog sastava etarskog ulja tri 
različita uzorka kamilice gajene u Pokrajini Vojvodini od strane individualnih poljoprivrednih proizvođača, može se zaključiti da domaće sorte “Banatska” i “Tetraploidna” sadrže β-farnezen kao dominantnu komponentu, dok je sadržaj bisabolol oksida i α-bisabolola niži nego što zahtevaju standardi u Evropskoj Farmakopeji, zbog čega se ne mogu kategorisati kao kvalitetni biljni materijal. Nemačka sorta “Mabamille” gajena u agroekološkim uslovima pokrajine Vojvodine, sa 37,5% α-bisabolola pripada bisabolol tipu kamilice i predstavlja visoko kvalitetnu sirovinu.
PB  - Novi Sad: Poljoprivredni fakultet
T2  - Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad
T1  - Essential oil quality of chamomile grown in Province of Vojvodina
VL  - 45
IS  - 1
SP  - 1
EP  - 8
UR  - https://hdl.handle.net/21.15107/rcub_cer_5167
ER  - 

@article{
author = "Aćimović, Milica and Stanković Jeremić, Jovana and Simić, Katarina and Ivanović, Stefan and Ljujić, Jovana and Čabarkapa, Ivana and Radojčin, Milivoj and Todosijević, Marina and Cvetković, Mirjana",
year = "2021",
abstract = "Chamomile (Matricaria chamomilla L., Asteraceae) is one of the most popular medicinal plants used as a herb
infusion for treating numerous ailments, including sleep disorders, anxiety, digestion and intestinal conditions
etc. Chamomile essential oil is used in a wide variety of consumer goods such as detergents, soaps, toiletries,
cosmetics, pharmaceuticals, perfumes, confectionery food products, soft drinks, distilled alcoholic beverages
(hard liquor) and as insecticide. According to the European Pharmacopoeia, there are two types of essential
oils, one rich in bisabolol oxides and the other in α-bisabolol, which are preferred for tea brewing because of
its sweet, grassy, and slightly fruity aroma. From the other side, varieties rich in chamazulene and β-farnesene
have bitter taste, and because of that they are low valuable raw material. According to the results of the
essential oil composition obtained from three different chamomile samples grown in Province of Vojvodina, it
could be concluded that domestic cultivars “Banatska” and “Tetraploidna” contains β-farnesene as dominant
compound, while the content of bisabolol oxides and α-bisabolol was lower than required standards in
European Pharmacopoeia. Because of that they could not be classified as quality raw material. The German
cultivar “Mabamille” grown in agroecological conditions of Vojvodina region, with 37.5% of α-bisabolol can be
classified as a bisabolol rich type, and as high quality row material., Kamilica (Matricaria chamomilla L., Asteraceae) je jedna od najpopularnijih lekovitih biljaka koja se 
upotrebljava u obliku infuza (čaja) za lečenje mnogih stanja i bolesti, uključujući poremećaje sna, napetost, probleme organa za varenje itd. Etarsko ulje kamilice se koristi u mnogim granama industrije: hemijskoj (kao dodatak deterdžentima), kozmetičkoj (u sapunima, sredstvima za ličnu higijenu), farmaceutskoj, parfimerijskoj i prehrambenoj industriji (u slatkišima, alkoholnim i bezalkoholnim pićima) i kao insekticid. Prema Evropskoj Farmakopeji, postoje dva tipa etarskog ulja kamilice, prvi koji je bogat bisabolol oksidima i drugi bogat α-bisabololom. Oba tipa su poželjna u industriji čajnih napitaka zbog njihovog slatkog, osvežavajućeg ukusa blago voćne arome. Sa druge strane, varijeteti bogati hamazulenom i β-farnezenom imaju gorak ukus i zbog toga predstavljaju manje vrednu biljnu sirovinu. Na osnovu rezultata hemijskog sastava etarskog ulja tri 
različita uzorka kamilice gajene u Pokrajini Vojvodini od strane individualnih poljoprivrednih proizvođača, može se zaključiti da domaće sorte “Banatska” i “Tetraploidna” sadrže β-farnezen kao dominantnu komponentu, dok je sadržaj bisabolol oksida i α-bisabolola niži nego što zahtevaju standardi u Evropskoj Farmakopeji, zbog čega se ne mogu kategorisati kao kvalitetni biljni materijal. Nemačka sorta “Mabamille” gajena u agroekološkim uslovima pokrajine Vojvodine, sa 37,5% α-bisabolola pripada bisabolol tipu kamilice i predstavlja visoko kvalitetnu sirovinu.",
publisher = "Novi Sad: Poljoprivredni fakultet",
journal = "Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad",
title = "Essential oil quality of chamomile grown in Province of Vojvodina",
volume = "45",
number = "1",
pages = "1-8",
url = "https://hdl.handle.net/21.15107/rcub_cer_5167"
}

Aćimović, M., Stanković Jeremić, J., Simić, K., Ivanović, S., Ljujić, J., Čabarkapa, I., Radojčin, M., Todosijević, M.,& Cvetković, M.. (2021). Essential oil quality of chamomile grown in Province of Vojvodina. in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad
Novi Sad: Poljoprivredni fakultet., 45(1), 1-8.
https://hdl.handle.net/21.15107/rcub_cer_5167

Aćimović M, Stanković Jeremić J, Simić K, Ivanović S, Ljujić J, Čabarkapa I, Radojčin M, Todosijević M, Cvetković M. Essential oil quality of chamomile grown in Province of Vojvodina. in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad. 2021;45(1):1-8.
https://hdl.handle.net/21.15107/rcub_cer_5167 .

Aćimović, Milica, Stanković Jeremić, Jovana, Simić, Katarina, Ivanović, Stefan, Ljujić, Jovana, Čabarkapa, Ivana, Radojčin, Milivoj, Todosijević, Marina, Cvetković, Mirjana, "Essential oil quality of chamomile grown in Province of Vojvodina" in Letopis naučnih radova Poljoprivrednog fakulteta, Novi Sad, 45, no. 1 (2021):1-8,
https://hdl.handle.net/21.15107/rcub_cer_5167 .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Stanković Jeremić, Jovana
AU  - Todosijević, Marina
AU  - Rat, Milica
AU  - Tešević, Vele
AU  - Cvetković, Mirjana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5291
AB  - In the essential oil of yarrow (Achillea millefolium L. sensu lato) collected from natural popula-
tion on Mt. Rtanj (Serbia) and distilled by Clevenger apparatus 104 compounds were detected, and

the most abundant were camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-

cineole (5.6%). The quantitative structure-retention relationship (QSRR) model was employed to pre-
dict the retention indices, using four molecular descriptors selected by factor analysis and a genetic

algorithm. The coefficients of determination reached the value of 0.862, demonstrating that this mo-
del could be used for prediction purposes.
PB  - Novi Sad : Faculty of Technology
T2  - Acta Periodica Technologica
T1  - The quantitative structure retention relationship of the gs ms profile of yarrow essential oil
IS  - 52
SP  - 123
EP  - 132
DO  - 10.2298/APT2152123A
ER  - 

@article{
author = "Aćimović, Milica and Pezo, Lato and Stanković Jeremić, Jovana and Todosijević, Marina and Rat, Milica and Tešević, Vele and Cvetković, Mirjana",
year = "2021",
abstract = "In the essential oil of yarrow (Achillea millefolium L. sensu lato) collected from natural popula-
tion on Mt. Rtanj (Serbia) and distilled by Clevenger apparatus 104 compounds were detected, and

the most abundant were camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-

cineole (5.6%). The quantitative structure-retention relationship (QSRR) model was employed to pre-
dict the retention indices, using four molecular descriptors selected by factor analysis and a genetic

algorithm. The coefficients of determination reached the value of 0.862, demonstrating that this mo-
del could be used for prediction purposes.",
publisher = "Novi Sad : Faculty of Technology",
journal = "Acta Periodica Technologica",
title = "The quantitative structure retention relationship of the gs ms profile of yarrow essential oil",
number = "52",
pages = "123-132",
doi = "10.2298/APT2152123A"
}

Aćimović, M., Pezo, L., Stanković Jeremić, J., Todosijević, M., Rat, M., Tešević, V.,& Cvetković, M.. (2021). The quantitative structure retention relationship of the gs ms profile of yarrow essential oil. in Acta Periodica Technologica
Novi Sad : Faculty of Technology.(52), 123-132.
https://doi.org/10.2298/APT2152123A

Aćimović M, Pezo L, Stanković Jeremić J, Todosijević M, Rat M, Tešević V, Cvetković M. The quantitative structure retention relationship of the gs ms profile of yarrow essential oil. in Acta Periodica Technologica. 2021;(52):123-132.
doi:10.2298/APT2152123A .

Aćimović, Milica, Pezo, Lato, Stanković Jeremić, Jovana, Todosijević, Marina, Rat, Milica, Tešević, Vele, Cvetković, Mirjana, "The quantitative structure retention relationship of the gs ms profile of yarrow essential oil" in Acta Periodica Technologica, no. 52 (2021):123-132,
https://doi.org/10.2298/APT2152123A . .

TY  - CONF
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Cvetković, Mirjana
AU  - Tešević, Vele
AU  - Sofrenić, Ivana
AU  - Ivanović, Stefan
AU  - Novaković, Miroslav
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5527
AB  - A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-D-glucuronopyranosyl-(1→2)-β-Dglucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-
D-glucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-L-arabinopyranoside-30-alolean-12-en-28-
oate (2), named atriplexogenin I, β-D glucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-Larabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-D-glucopyranosyl-3-
O-(β-D-glucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→2)-α-L-arabinopyranoside)-30-alolean-12-en-28-oate
(4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography
from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary
metabolites, patuletin 3-O-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (5) and patuletin 3-O-5‴-Oferuloyl-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (6), were isolated for the first time from A. tatarica.
The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data.
Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed.
The best activity against Micrococcus flavus and Pseudomonas aeruginosa showed compound 1, while against
Listeria monocytogenes and Escherichia coli the strongest activity was shown by compound 5. Isolated
saponins (2-4) exhibited a more pronounced biofilm inhibition activity than flavonoid glycosides (1, 5-6). The
best anti-biofilm activity showed compound 2.
PB  - Portugal : PROTEOMASS Scientific Society
C3  - Book of abstracts - 5th International Caparica Christmas Conference on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal
T1  - Antibacterial	 and	 Antibiofilm	 Activity	 of	 Flavonoid	 and	 Saponin	 Derivatives	 from	 Atriplex	 tatarica against	 Pseudomonas	 aeruginosa
SP  - 150
EP  - 150
UR  - https://hdl.handle.net/21.15107/rcub_cer_5527
ER  - 

@conference{
author = "Stanković, Jovana and Gođevac, Dejan and Cvetković, Mirjana and Tešević, Vele and Sofrenić, Ivana and Ivanović, Stefan and Novaković, Miroslav",
year = "2021",
abstract = "A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-D-glucuronopyranosyl-(1→2)-β-Dglucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-
D-glucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-L-arabinopyranoside-30-alolean-12-en-28-
oate (2), named atriplexogenin I, β-D glucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-Larabinopyranoside)-30-hydroxyolean-12-en-28-oate (3), named atriplexogenin II, and β-D-glucopyranosyl-3-
O-(β-D-glucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→2)-α-L-arabinopyranoside)-30-alolean-12-en-28-oate
(4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography
from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary
metabolites, patuletin 3-O-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (5) and patuletin 3-O-5‴-Oferuloyl-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (6), were isolated for the first time from A. tatarica.
The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data.
Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed.
The best activity against Micrococcus flavus and Pseudomonas aeruginosa showed compound 1, while against
Listeria monocytogenes and Escherichia coli the strongest activity was shown by compound 5. Isolated
saponins (2-4) exhibited a more pronounced biofilm inhibition activity than flavonoid glycosides (1, 5-6). The
best anti-biofilm activity showed compound 2.",
publisher = "Portugal : PROTEOMASS Scientific Society",
journal = "Book of abstracts - 5th International Caparica Christmas Conference on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal",
title = "Antibacterial	 and	 Antibiofilm	 Activity	 of	 Flavonoid	 and	 Saponin	 Derivatives	 from	 Atriplex	 tatarica against	 Pseudomonas	 aeruginosa",
pages = "150-150",
url = "https://hdl.handle.net/21.15107/rcub_cer_5527"
}

Stanković, J., Gođevac, D., Cvetković, M., Tešević, V., Sofrenić, I., Ivanović, S.,& Novaković, M.. (2021). Antibacterial	 and	 Antibiofilm	 Activity	 of	 Flavonoid	 and	 Saponin	 Derivatives	 from	 Atriplex	 tatarica against	 Pseudomonas	 aeruginosa. in Book of abstracts - 5th International Caparica Christmas Conference on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal
Portugal : PROTEOMASS Scientific Society., 150-150.
https://hdl.handle.net/21.15107/rcub_cer_5527

Stanković J, Gođevac D, Cvetković M, Tešević V, Sofrenić I, Ivanović S, Novaković M. Antibacterial	 and	 Antibiofilm	 Activity	 of	 Flavonoid	 and	 Saponin	 Derivatives	 from	 Atriplex	 tatarica against	 Pseudomonas	 aeruginosa. in Book of abstracts - 5th International Caparica Christmas Conference on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal. 2021;:150-150.
https://hdl.handle.net/21.15107/rcub_cer_5527 .

Stanković, Jovana, Gođevac, Dejan, Cvetković, Mirjana, Tešević, Vele, Sofrenić, Ivana, Ivanović, Stefan, Novaković, Miroslav, "Antibacterial	 and	 Antibiofilm	 Activity	 of	 Flavonoid	 and	 Saponin	 Derivatives	 from	 Atriplex	 tatarica against	 Pseudomonas	 aeruginosa" in Book of abstracts - 5th International Caparica Christmas Conference on Sample Treatment (ST 2021), 15th – 18th November 2021, Caparica, Portugal (2021):150-150,
https://hdl.handle.net/21.15107/rcub_cer_5527 .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Pezo, Lato L.
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Čabarkapa, Ivana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4710
AB  - The aim of this study was the prediction model of retention indices of compounds from the aboveground parts of Achillea clypeolata Sibth. & Sm. essential oil, obtained by hydrodistillation and analysed by GC-MS. The quantitative structure-retention relationship analysis was applied in order to anticipate the retention time of the obtained compounds. The selection of the seven molecular descriptors was done by a genetic algorithm. The chosen descriptors were uncorrelated and were used to construct an artificial neural network. A total of 40 experimentally obtained retention indices was used to build this prediction model. The coefficient of determination for the training, testing and validation cycles were: 0.950, 0.825 and 1.000, respectively, indicating that this model could be used for prediction of retention indices for A.
AB  - Циљ ове студије био је израда модела за предвиђања ретенционог времена хемијских једињења из есенцијалног уља надземних делова биљке Achillea clypeolata Sibth. & Sm., добијеног хидродистилацијом и анализираног GC–MS техником. Квантитативна анализа хемијске структуре и предвиђања ретенционог времена (quantitative structure– retention relationship – QSRR) је примењена да би се предвидело време задржавања хемијских једињења добијених коришћењем GC–MS анализе. Избор седам молекулских дескриптора извршен је коришћењем факторске анализе и генетског алгоритма. Примећено је да изабрани дескриптори нису били у међусобној корелацији, па су коришћени као улазни подаци при изградњи вештачке неуронске мреже. У изградњи модела предвиђања ретенционих времена коришћено је укупно 40 експериментално добијених ретенционих времена. Коефицијент детерминације током циклуса припреме, тестирања и i валидације достигао је вредности 0,950; 0,825 и 1,000, редом, што указује на то да се овај модел може користити за предвиђање ретенционих времена хемијских једињења добијених из есенцијалног уља A. clypeolata
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices
T1  - Hemijski sastav etarskog ulja Achillea clypeolata Sibth. & Sm. И QSRR model za predviđanje retencionog vremena
VL  - 86
IS  - 4
SP  - 355
EP  - 366
DO  - 10.2298/JSC200524008A
ER  - 

@article{
author = "Aćimović, Milica G. and Pezo, Lato L. and Cvetković, Mirjana and Stanković, Jovana and Čabarkapa, Ivana",
year = "2021",
abstract = "The aim of this study was the prediction model of retention indices of compounds from the aboveground parts of Achillea clypeolata Sibth. & Sm. essential oil, obtained by hydrodistillation and analysed by GC-MS. The quantitative structure-retention relationship analysis was applied in order to anticipate the retention time of the obtained compounds. The selection of the seven molecular descriptors was done by a genetic algorithm. The chosen descriptors were uncorrelated and were used to construct an artificial neural network. A total of 40 experimentally obtained retention indices was used to build this prediction model. The coefficient of determination for the training, testing and validation cycles were: 0.950, 0.825 and 1.000, respectively, indicating that this model could be used for prediction of retention indices for A., Циљ ове студије био је израда модела за предвиђања ретенционог времена хемијских једињења из есенцијалног уља надземних делова биљке Achillea clypeolata Sibth. & Sm., добијеног хидродистилацијом и анализираног GC–MS техником. Квантитативна анализа хемијске структуре и предвиђања ретенционог времена (quantitative structure– retention relationship – QSRR) је примењена да би се предвидело време задржавања хемијских једињења добијених коришћењем GC–MS анализе. Избор седам молекулских дескриптора извршен је коришћењем факторске анализе и генетског алгоритма. Примећено је да изабрани дескриптори нису били у међусобној корелацији, па су коришћени као улазни подаци при изградњи вештачке неуронске мреже. У изградњи модела предвиђања ретенционих времена коришћено је укупно 40 експериментално добијених ретенционих времена. Коефицијент детерминације током циклуса припреме, тестирања и i валидације достигао је вредности 0,950; 0,825 и 1,000, редом, што указује на то да се овај модел може користити за предвиђање ретенционих времена хемијских једињења добијених из есенцијалног уља A. clypeolata",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices, Hemijski sastav etarskog ulja Achillea clypeolata Sibth. & Sm. И QSRR model za predviđanje retencionog vremena",
volume = "86",
number = "4",
pages = "355-366",
doi = "10.2298/JSC200524008A"
}

Aćimović, M. G., Pezo, L. L., Cvetković, M., Stanković, J.,& Čabarkapa, I.. (2021). Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 86(4), 355-366.
https://doi.org/10.2298/JSC200524008A

Aćimović MG, Pezo LL, Cvetković M, Stanković J, Čabarkapa I. Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices. in Journal of the Serbian Chemical Society. 2021;86(4):355-366.
doi:10.2298/JSC200524008A .

Aćimović, Milica G., Pezo, Lato L., Cvetković, Mirjana, Stanković, Jovana, Čabarkapa, Ivana, "Achillea clypeolata sibth. & sm. essential oil composition and qsrr model for predicting retention indices" in Journal of the Serbian Chemical Society, 86, no. 4 (2021):355-366,
https://doi.org/10.2298/JSC200524008A . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Zorić, Miroslav
AU  - Zheljazkov, Valtcho
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Stanković Jeremić, Jovana
AU  - Cvetković, Mirjana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3952
AB  - The objective of this study was to evaluate wild growing Satureja kitaibelii, Thymus serpyllum,
Origanum vulgare, Achillea millefolium and Achillea clypeolata with respect to their essential oil (EO)
content, composition and antimicrobial activity. The five species were collected at Mt. Rtanj and the
village of Sesalac, Eastern Serbia. The main EO constituents of Lamiaceae plants were p-cymene
(24.4%), geraniol (63.4%) and germacrene D (21.5%) in Satureja kitaibelii, Thymus serpyllum and
Origanum vulgare ssp. vulgare, respectively. A. millefolium EO had multiple constituents with major
ones being camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-cineole (5.6%),
while the main EO constituents of A. clypeolata were 1,8-cineole (45.1%) and camphor (18.2%).
Antimicrobial testing of the EO showed that Staphylococcus aureus (Gram-positive) was more sensitive
to all of the tested EOs than Escherichia coli (Gram-negative). S. kitaibelii EO showed the highest
antimicrobial activity against both tested bacterial strains. This is the first study to characterize
the EO composition and antimicrobial activity of these five medicinal species from Eastern Serbia
in comparison with comprehensive literature data. The results can be utilized by the perfumery,
cosmetics, food and pharmaceutical industries, but also for healing purposes in self-medication.
PB  - MDPI
T2  - Molecules
T1  - Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia
VL  - 25
IS  - 22
SP  - 5482
DO  - 10.3390/molecules25225482
ER  - 

@article{
author = "Aćimović, Milica and Zorić, Miroslav and Zheljazkov, Valtcho and Pezo, Lato and Čabarkapa, Ivana and Stanković Jeremić, Jovana and Cvetković, Mirjana",
year = "2020",
abstract = "The objective of this study was to evaluate wild growing Satureja kitaibelii, Thymus serpyllum,
Origanum vulgare, Achillea millefolium and Achillea clypeolata with respect to their essential oil (EO)
content, composition and antimicrobial activity. The five species were collected at Mt. Rtanj and the
village of Sesalac, Eastern Serbia. The main EO constituents of Lamiaceae plants were p-cymene
(24.4%), geraniol (63.4%) and germacrene D (21.5%) in Satureja kitaibelii, Thymus serpyllum and
Origanum vulgare ssp. vulgare, respectively. A. millefolium EO had multiple constituents with major
ones being camphor (9.8%), caryophyllene oxide (6.5%), terpinen-4-ol (6.3%) and 1,8-cineole (5.6%),
while the main EO constituents of A. clypeolata were 1,8-cineole (45.1%) and camphor (18.2%).
Antimicrobial testing of the EO showed that Staphylococcus aureus (Gram-positive) was more sensitive
to all of the tested EOs than Escherichia coli (Gram-negative). S. kitaibelii EO showed the highest
antimicrobial activity against both tested bacterial strains. This is the first study to characterize
the EO composition and antimicrobial activity of these five medicinal species from Eastern Serbia
in comparison with comprehensive literature data. The results can be utilized by the perfumery,
cosmetics, food and pharmaceutical industries, but also for healing purposes in self-medication.",
publisher = "MDPI",
journal = "Molecules",
title = "Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia",
volume = "25",
number = "22",
pages = "5482",
doi = "10.3390/molecules25225482"
}

Aćimović, M., Zorić, M., Zheljazkov, V., Pezo, L., Čabarkapa, I., Stanković Jeremić, J.,& Cvetković, M.. (2020). Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia. in Molecules
MDPI., 25(22), 5482.
https://doi.org/10.3390/molecules25225482

Aćimović M, Zorić M, Zheljazkov V, Pezo L, Čabarkapa I, Stanković Jeremić J, Cvetković M. Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia. in Molecules. 2020;25(22):5482.
doi:10.3390/molecules25225482 .

Aćimović, Milica, Zorić, Miroslav, Zheljazkov, Valtcho, Pezo, Lato, Čabarkapa, Ivana, Stanković Jeremić, Jovana, Cvetković, Mirjana, "Chemical characterization and antibacterial activity of essential oil of medicinal plants from Eastern Serbia" in Molecules, 25, no. 22 (2020):5482,
https://doi.org/10.3390/molecules25225482 . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Todosijević, Marina
AU  - Đorđević, Iris
AU  - Stanković, Jovana
AU  - Mitić, Zorica S.
AU  - Tešević, Vele
AU  - Marin, Petar D.
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3620
AB  - In needle cuticular wax of Pinus halepensis, nonacosan-10-ol
is high (77.08% on average). n-Alkanes
ranged from C18 to C35 with the
most dominant C27 and C29 (32.4% and 25.8%, respectively). The carbon preference index ranged from 3.2 to 5.4 (3.4 on average),
while the average chain length ranged from 14.0 to 18.0 (17.2 on average). Long-chain
n-alkanes
strongly dominated (95.1%).
PB  - SAGE Publications Inc.
T2  - Natural Product Communications
T1  - Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis
VL  - 15
IS  - 5
SP  - 1
EP  - 4
DO  - 10.1177/1934578X20920970
ER  - 

@article{
author = "Nikolić, Biljana and Todosijević, Marina and Đorđević, Iris and Stanković, Jovana and Mitić, Zorica S. and Tešević, Vele and Marin, Petar D.",
year = "2020",
abstract = "In needle cuticular wax of Pinus halepensis, nonacosan-10-ol
is high (77.08% on average). n-Alkanes
ranged from C18 to C35 with the
most dominant C27 and C29 (32.4% and 25.8%, respectively). The carbon preference index ranged from 3.2 to 5.4 (3.4 on average),
while the average chain length ranged from 14.0 to 18.0 (17.2 on average). Long-chain
n-alkanes
strongly dominated (95.1%).",
publisher = "SAGE Publications Inc.",
journal = "Natural Product Communications",
title = "Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis",
volume = "15",
number = "5",
pages = "1-4",
doi = "10.1177/1934578X20920970"
}

Nikolić, B., Todosijević, M., Đorđević, I., Stanković, J., Mitić, Z. S., Tešević, V.,& Marin, P. D.. (2020). Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis. in Natural Product Communications
SAGE Publications Inc.., 15(5), 1-4.
https://doi.org/10.1177/1934578X20920970

Nikolić B, Todosijević M, Đorđević I, Stanković J, Mitić ZS, Tešević V, Marin PD. Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis. in Natural Product Communications. 2020;15(5):1-4.
doi:10.1177/1934578X20920970 .

Nikolić, Biljana, Todosijević, Marina, Đorđević, Iris, Stanković, Jovana, Mitić, Zorica S., Tešević, Vele, Marin, Petar D., "Nonacosan-10-ol and n-Alkanes in Needles of Pinus halepensis" in Natural Product Communications, 15, no. 5 (2020):1-4,
https://doi.org/10.1177/1934578X20920970 . .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Todosijević, Marina
AU  - Đorđević, Iris
AU  - Stanković, Jovana
AU  - Mitić, Zorica S.
AU  - Marin, Petar D.
AU  - Tešević, Vele
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3953
AB  - In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35
with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the
average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated
(80.1%) over middle-chain (n-C21-24 = 18.9%) and short-chain (n-C18-20 = 0.9%) n-alkanes.
PB  - SAGE Publications Inc.
T2  - Natural Product Communications
T1  - Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster
VL  - 15
IS  - 5
SP  - 1
EP  - 4
DO  - 10.1177/1934578X20926073
ER  - 

@article{
author = "Nikolić, Biljana and Todosijević, Marina and Đorđević, Iris and Stanković, Jovana and Mitić, Zorica S. and Marin, Petar D. and Tešević, Vele",
year = "2020",
abstract = "In leaf cuticular wax of Pinus pinaster, content of nonacosan-10-ol is high (77.1% on average). n-Alkanes ranged from C18 to C35
with the most dominant C29 (24.8%). The carbon preference index (CPItotal) ranged from 3.1 to 5.6 (4.0 on average), while the
average chain length (ACLtotal) ranged from 14.0 to 17.0 (14.8 on average). Long-chain n-alkanes (n-C25-35) strongly dominated
(80.1%) over middle-chain (n-C21-24 = 18.9%) and short-chain (n-C18-20 = 0.9%) n-alkanes.",
publisher = "SAGE Publications Inc.",
journal = "Natural Product Communications",
title = "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster",
volume = "15",
number = "5",
pages = "1-4",
doi = "10.1177/1934578X20926073"
}

Nikolić, B., Todosijević, M., Đorđević, I., Stanković, J., Mitić, Z. S., Marin, P. D.,& Tešević, V.. (2020). Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications
SAGE Publications Inc.., 15(5), 1-4.
https://doi.org/10.1177/1934578X20926073

Nikolić B, Todosijević M, Đorđević I, Stanković J, Mitić ZS, Marin PD, Tešević V. Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster. in Natural Product Communications. 2020;15(5):1-4.
doi:10.1177/1934578X20926073 .

Nikolić, Biljana, Todosijević, Marina, Đorđević, Iris, Stanković, Jovana, Mitić, Zorica S., Marin, Petar D., Tešević, Vele, "Nonacosan-10-ol and n-Alkanes in Leaves of Pinus pinaster" in Natural Product Communications, 15, no. 5 (2020):1-4,
https://doi.org/10.1177/1934578X20926073 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Pezo, Lato
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Rat, Milica
AU  - Čabarkapa, Ivana
AU  - Tešević, Vele
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3951
AB  - A total of 26 experimentally obtained retention indices on a logarithmic scale (log RI) from
Thymus serpyllum essential oil were used to build a robust predictive model. The selected descriptors were
used as inputs of an artificial neural network model to build a predictive quantitative structure-retention time
relationship model. The coefficient of determination for the training cycle was 0.977, indicating that this model
could be used for the prediction of retention indices for T. serpyllum essential oil compounds. These 26
compounds comprise about 99.8 % of the total oil, but among them only 6 compounds had the average relative
concentration over 1 percent: geraniol (63.4 %), nerol (or cis-geraniol) (18.9 %), geranyl acetate (4.7 %), transcaryophyllene (4.6 %), β-bisabolene (2.0 %) and geranial (1.2 %). According to these results, it can be concluded
that T. serpyllum from village Sesalac (Serbia) belongs to geraniol chemotype, in total 82.3 % in both, trans and
cis forms (63.4 % and 18.9 %, respectively).
PB  - Taylor & Francis
T2  - Essential Oil Bearing Plants
T1  - QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil
VL  - 23
IS  - 3
SP  - 464
EP  - 473
DO  - 10.1080/0972060X.2020.1790428
ER  - 

@article{
author = "Aćimović, Milica and Pezo, Lato and Stanković, Jovana and Cvetković, Mirjana and Rat, Milica and Čabarkapa, Ivana and Tešević, Vele",
year = "2020",
abstract = "A total of 26 experimentally obtained retention indices on a logarithmic scale (log RI) from
Thymus serpyllum essential oil were used to build a robust predictive model. The selected descriptors were
used as inputs of an artificial neural network model to build a predictive quantitative structure-retention time
relationship model. The coefficient of determination for the training cycle was 0.977, indicating that this model
could be used for the prediction of retention indices for T. serpyllum essential oil compounds. These 26
compounds comprise about 99.8 % of the total oil, but among them only 6 compounds had the average relative
concentration over 1 percent: geraniol (63.4 %), nerol (or cis-geraniol) (18.9 %), geranyl acetate (4.7 %), transcaryophyllene (4.6 %), β-bisabolene (2.0 %) and geranial (1.2 %). According to these results, it can be concluded
that T. serpyllum from village Sesalac (Serbia) belongs to geraniol chemotype, in total 82.3 % in both, trans and
cis forms (63.4 % and 18.9 %, respectively).",
publisher = "Taylor & Francis",
journal = "Essential Oil Bearing Plants",
title = "QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil",
volume = "23",
number = "3",
pages = "464-473",
doi = "10.1080/0972060X.2020.1790428"
}

Aćimović, M., Pezo, L., Stanković, J., Cvetković, M., Rat, M., Čabarkapa, I.,& Tešević, V.. (2020). QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil. in Essential Oil Bearing Plants
Taylor & Francis., 23(3), 464-473.
https://doi.org/10.1080/0972060X.2020.1790428

Aćimović M, Pezo L, Stanković J, Cvetković M, Rat M, Čabarkapa I, Tešević V. QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil. in Essential Oil Bearing Plants. 2020;23(3):464-473.
doi:10.1080/0972060X.2020.1790428 .

Aćimović, Milica, Pezo, Lato, Stanković, Jovana, Cvetković, Mirjana, Rat, Milica, Čabarkapa, Ivana, Tešević, Vele, "QSRR model for predicting retention indices of geraniol chemotype of Thymus serpyllum essential oil" in Essential Oil Bearing Plants, 23, no. 3 (2020):464-473,
https://doi.org/10.1080/0972060X.2020.1790428 . .

TY  - CONF
AU  - Aćimović, Milica
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Simin, Nataša
AU  - Beara, Ivana
AU  - Lesjak, Marija
AU  - Popović, Vera
PY  - 2020
UR  - uri:http://www.gea.ucg.ac.me
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3954
AB  - Most of the Origanum species are locally distributed within the Mediterranean region
where they grow in the mountainous areas on the islands. Due to this, the rate of endemism is high,
as in case of dittany of Crete (O. dictamnus). O. vulgare possesses the largest distribution area and can
be found throughout the Mediterranean region, however, the yield and quality of the essential oil is
controlled genetically and strongly affected by the environmental influences. Origanum essential oils
predominantly containing carvacrol, are generally of superior quality and highly valuable raw
material for food as well as in pharmaceutical industry. Essential oil of O. dictimus contains 70.8% of
carvacrol, while O. vulgare ssp. hirtum essential oil contains 78.5%. This study indicates the high
quality of investigated Origanum species from Greece, and indicates it to be highly valuable raw
material for food and in pharmaceutical industry.
PB  - Faculty of Architecture – University of Montenegro
PB  - Faculty of Philosophy - University of Montenegro
PB  - Biotecnical faculty - University of Montenegro
C3  - Book of Proceedings - GEA (Geo Eco-Eco Agro) International Conference
T1  - Chemical composition of Origanum dictamnus and Origanum vulgare ssp. hirtum from Greece
VL  - 1
SP  - 244
EP  - 249
UR  - https://hdl.handle.net/21.15107/rcub_cer_3954
ER  - 

@conference{
author = "Aćimović, Milica and Stanković, Jovana and Cvetković, Mirjana and Simin, Nataša and Beara, Ivana and Lesjak, Marija and Popović, Vera",
year = "2020",
abstract = "Most of the Origanum species are locally distributed within the Mediterranean region
where they grow in the mountainous areas on the islands. Due to this, the rate of endemism is high,
as in case of dittany of Crete (O. dictamnus). O. vulgare possesses the largest distribution area and can
be found throughout the Mediterranean region, however, the yield and quality of the essential oil is
controlled genetically and strongly affected by the environmental influences. Origanum essential oils
predominantly containing carvacrol, are generally of superior quality and highly valuable raw
material for food as well as in pharmaceutical industry. Essential oil of O. dictimus contains 70.8% of
carvacrol, while O. vulgare ssp. hirtum essential oil contains 78.5%. This study indicates the high
quality of investigated Origanum species from Greece, and indicates it to be highly valuable raw
material for food and in pharmaceutical industry.",
publisher = "Faculty of Architecture – University of Montenegro, Faculty of Philosophy - University of Montenegro, Biotecnical faculty - University of Montenegro",
journal = "Book of Proceedings - GEA (Geo Eco-Eco Agro) International Conference",
title = "Chemical composition of Origanum dictamnus and Origanum vulgare ssp. hirtum from Greece",
volume = "1",
pages = "244-249",
url = "https://hdl.handle.net/21.15107/rcub_cer_3954"
}

Aćimović, M., Stanković, J., Cvetković, M., Simin, N., Beara, I., Lesjak, M.,& Popović, V.. (2020). Chemical composition of Origanum dictamnus and Origanum vulgare ssp. hirtum from Greece. in Book of Proceedings - GEA (Geo Eco-Eco Agro) International Conference
Faculty of Architecture – University of Montenegro., 1, 244-249.
https://hdl.handle.net/21.15107/rcub_cer_3954

Aćimović M, Stanković J, Cvetković M, Simin N, Beara I, Lesjak M, Popović V. Chemical composition of Origanum dictamnus and Origanum vulgare ssp. hirtum from Greece. in Book of Proceedings - GEA (Geo Eco-Eco Agro) International Conference. 2020;1:244-249.
https://hdl.handle.net/21.15107/rcub_cer_3954 .

Aćimović, Milica, Stanković, Jovana, Cvetković, Mirjana, Simin, Nataša, Beara, Ivana, Lesjak, Marija, Popović, Vera, "Chemical composition of Origanum dictamnus and Origanum vulgare ssp. hirtum from Greece" in Book of Proceedings - GEA (Geo Eco-Eco Agro) International Conference, 1 (2020):244-249,
https://hdl.handle.net/21.15107/rcub_cer_3954 .

TY  - JOUR
AU  - Krstić, Gordana
AU  - Aljančić, Ivana
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Marin, Petar D.
AU  - Janaćković, Peđa T.
AU  - Tešević, Vele
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2923
AB  - The presence of n-alkanes, free alcohols and free acids in leaf epicuticular wax extracts of 22 samples of 11 Euphorbia L. species belonging to the sections Paralias, Esula, Myrsiniteae and Helioscopia, 10 of which were never examined before, were analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS), and n-alkane C27 was detected as the principal component of leaf epicuticular waxes in the majority of the examined species, while the most abundant free alcohol was C26. Three Euphorbia species belonging to section Helioscopia were characterized by a predominance of alcohol C28. Free acid (C16) was the major component in 21 investigated samples. The usefulness of n-alkanes and free alcohols and free acids as potential chemotaxonomic markers is briefly discussed.
T2  - Archives of Biological Sciences
T1  - Leaf epicuticular waxes of eleven Euphorbia species (Euphorbiaceae) from the central Balkans: Impact on chemotaxonomy
VL  - 71
IS  - 1
SP  - 21
EP  - 26
DO  - 10.2298/ABS180608041K
ER  - 

@article{
author = "Krstić, Gordana and Aljančić, Ivana and Stanković, Jovana and Cvetković, Mirjana and Marin, Petar D. and Janaćković, Peđa T. and Tešević, Vele",
year = "2019",
abstract = "The presence of n-alkanes, free alcohols and free acids in leaf epicuticular wax extracts of 22 samples of 11 Euphorbia L. species belonging to the sections Paralias, Esula, Myrsiniteae and Helioscopia, 10 of which were never examined before, were analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS), and n-alkane C27 was detected as the principal component of leaf epicuticular waxes in the majority of the examined species, while the most abundant free alcohol was C26. Three Euphorbia species belonging to section Helioscopia were characterized by a predominance of alcohol C28. Free acid (C16) was the major component in 21 investigated samples. The usefulness of n-alkanes and free alcohols and free acids as potential chemotaxonomic markers is briefly discussed.",
journal = "Archives of Biological Sciences",
title = "Leaf epicuticular waxes of eleven Euphorbia species (Euphorbiaceae) from the central Balkans: Impact on chemotaxonomy",
volume = "71",
number = "1",
pages = "21-26",
doi = "10.2298/ABS180608041K"
}

Krstić, G., Aljančić, I., Stanković, J., Cvetković, M., Marin, P. D., Janaćković, P. T.,& Tešević, V.. (2019). Leaf epicuticular waxes of eleven Euphorbia species (Euphorbiaceae) from the central Balkans: Impact on chemotaxonomy. in Archives of Biological Sciences, 71(1), 21-26.
https://doi.org/10.2298/ABS180608041K

Krstić G, Aljančić I, Stanković J, Cvetković M, Marin PD, Janaćković PT, Tešević V. Leaf epicuticular waxes of eleven Euphorbia species (Euphorbiaceae) from the central Balkans: Impact on chemotaxonomy. in Archives of Biological Sciences. 2019;71(1):21-26.
doi:10.2298/ABS180608041K .

Krstić, Gordana, Aljančić, Ivana, Stanković, Jovana, Cvetković, Mirjana, Marin, Petar D., Janaćković, Peđa T., Tešević, Vele, "Leaf epicuticular waxes of eleven Euphorbia species (Euphorbiaceae) from the central Balkans: Impact on chemotaxonomy" in Archives of Biological Sciences, 71, no. 1 (2019):21-26,
https://doi.org/10.2298/ABS180608041K . .

TY  - THES
AU  - Stanković, Jovana
PY  - 2019
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=7015
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:20623/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=51738383
UR  - http://nardus.mpn.gov.rs/123456789/11672
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3425
AB  - Predmet proučavanja ove doktorske disertacije su sekundarni metaboliti halofita(biljaka koje naseljavaju staništa sa visokim sadržajem soli). U Srbiji se zaslanjenastaništa uglavnom javljaju na teritoriji Vojvodine. U ovom radu izolovani su i hemijskiokarakterisani flavonoidni glikozidi i saponini iz halofitnih vrsta roda Atriplex (A.littoralis, A. tatarica i A. prostrata) i određena je njihova različita biološka aktivnost.Pored biljaka iz roda Atriplex ispitivana je halofitna biljna vrsta Artemisia santonicum izkoje je izolovano etarsko ulje, određen hemijski sastav i ispitana biološka aktivnost.Halofitne biljne vrste se u tradicionalnoj medicini koriste u brojne svrhe kaoantiseptici, diuretici, antiparazitici, antipiretici, purgativi, laksativi, za lečenjedijabetesa, visokog krvnog pritiska, astme, gihta i reumatizma. Ekstrakti i jedinjenjaizolovana iz vrsta roda Atriplex pokazuju antioksidativnu, antimikrobnu, citotoksičnu,antiparazitsku, i insekticidnu aktivnost. Etarska ulja vrsta roda Artemisia su pokazalaantioksidativnu, antibakterijsku, antifungalnu, antiparazitsku, hepatoprotektivnu,neuroprotektivnu i antimalarijsku aktivnost.Vrste roda Atriplex su bogat izvor sekundarnih metabolita prvenstvenoflavonoida, saponina i alkaloida. U okviru ove disertacije izolovano je i okarakterisanoukupno 13 jedinjenja, od kojih je 7 novih prirodnih proizvoda (43-45, 51-54). Iz vrste A.littoralis izolovano je 6 jedinjenja, četiri flavonoidna glikozida (43-46) i dva fenolnajedinjenja (47, 48). Iz A. tatarica izolovano je 6 jedinjenja, tri flavonoidna glikozida(49-51) i tri triterpenska saponina oleanolnog tipa (52-54). Iz etarskog ulja Artemisiasantonicum izolovan je oksigenovani monoterpen (55)...
AB  - The subject of this doctoral dissertation are the secondary metabolites ofhalophytes (plants wild growing at saline habitats). In Serbia such habitats are mainlyfound in Vojvodina. Flavonoid glycosides and saponins from halophytic speciesAtriplex (A. littoralis, A. tatarica and A. prostrata) were isolated, chemicallycharacterized and their various biological activities were determined. In addition, ahalophyte species from the genus Artemisia (A. santonicum) was examined. Its essentialoil was isolated, the chemical composition determined and various biological activitiesof this were tested.Several halophytic plant species are used in many traditional formulations asantiseptics, diuretics, antiparasitics, antipyretics, purgatives, laxatives, for the treatmentof diabetes, high blood pressure, asthma, gout and rheumatism. Extracts and compoundsisolated from the genus Atriplex show antiparasitic, insecticidal, antimicrobial,cytotoxic and antioxidant activity. Essential oils of the genus Artemisia have shownantioxidant, antibacterial, antifungal, antiparasitic, hepatoprotective, neuroprotectiveand antimalarial activity.Atriplex species are a rich source of secondary metabolites, primarily flavonoids,saponins and alkaloids. In this study, a total of 13 compounds were isolated andcharacterized by means of spectroscopic techniques (1D and 2D NMR, IR and MS).Among them seven (43-45, 51-54) were the new compounds. At the same time, in theextract of A. littoralis, six compounds, four flavonoid glycosides (43-46) and twophenolic compounds (47, 48) were identified. From A. tatarica six compounds, threeflavonoid glycosides (49-51) and three triterpene saponins of an oleanane type (52-54)were isolated. An oxygenated monoterpene (55) was isolated from Artemisiasantonicum essential oil...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita
UR  - https://hdl.handle.net/21.15107/rcub_nardus_11672
ER  - 

@phdthesis{
author = "Stanković, Jovana",
year = "2019",
abstract = "Predmet proučavanja ove doktorske disertacije su sekundarni metaboliti halofita(biljaka koje naseljavaju staništa sa visokim sadržajem soli). U Srbiji se zaslanjenastaništa uglavnom javljaju na teritoriji Vojvodine. U ovom radu izolovani su i hemijskiokarakterisani flavonoidni glikozidi i saponini iz halofitnih vrsta roda Atriplex (A.littoralis, A. tatarica i A. prostrata) i određena je njihova različita biološka aktivnost.Pored biljaka iz roda Atriplex ispitivana je halofitna biljna vrsta Artemisia santonicum izkoje je izolovano etarsko ulje, određen hemijski sastav i ispitana biološka aktivnost.Halofitne biljne vrste se u tradicionalnoj medicini koriste u brojne svrhe kaoantiseptici, diuretici, antiparazitici, antipiretici, purgativi, laksativi, za lečenjedijabetesa, visokog krvnog pritiska, astme, gihta i reumatizma. Ekstrakti i jedinjenjaizolovana iz vrsta roda Atriplex pokazuju antioksidativnu, antimikrobnu, citotoksičnu,antiparazitsku, i insekticidnu aktivnost. Etarska ulja vrsta roda Artemisia su pokazalaantioksidativnu, antibakterijsku, antifungalnu, antiparazitsku, hepatoprotektivnu,neuroprotektivnu i antimalarijsku aktivnost.Vrste roda Atriplex su bogat izvor sekundarnih metabolita prvenstvenoflavonoida, saponina i alkaloida. U okviru ove disertacije izolovano je i okarakterisanoukupno 13 jedinjenja, od kojih je 7 novih prirodnih proizvoda (43-45, 51-54). Iz vrste A.littoralis izolovano je 6 jedinjenja, četiri flavonoidna glikozida (43-46) i dva fenolnajedinjenja (47, 48). Iz A. tatarica izolovano je 6 jedinjenja, tri flavonoidna glikozida(49-51) i tri triterpenska saponina oleanolnog tipa (52-54). Iz etarskog ulja Artemisiasantonicum izolovan je oksigenovani monoterpen (55)..., The subject of this doctoral dissertation are the secondary metabolites ofhalophytes (plants wild growing at saline habitats). In Serbia such habitats are mainlyfound in Vojvodina. Flavonoid glycosides and saponins from halophytic speciesAtriplex (A. littoralis, A. tatarica and A. prostrata) were isolated, chemicallycharacterized and their various biological activities were determined. In addition, ahalophyte species from the genus Artemisia (A. santonicum) was examined. Its essentialoil was isolated, the chemical composition determined and various biological activitiesof this were tested.Several halophytic plant species are used in many traditional formulations asantiseptics, diuretics, antiparasitics, antipyretics, purgatives, laxatives, for the treatmentof diabetes, high blood pressure, asthma, gout and rheumatism. Extracts and compoundsisolated from the genus Atriplex show antiparasitic, insecticidal, antimicrobial,cytotoxic and antioxidant activity. Essential oils of the genus Artemisia have shownantioxidant, antibacterial, antifungal, antiparasitic, hepatoprotective, neuroprotectiveand antimalarial activity.Atriplex species are a rich source of secondary metabolites, primarily flavonoids,saponins and alkaloids. In this study, a total of 13 compounds were isolated andcharacterized by means of spectroscopic techniques (1D and 2D NMR, IR and MS).Among them seven (43-45, 51-54) were the new compounds. At the same time, in theextract of A. littoralis, six compounds, four flavonoid glycosides (43-46) and twophenolic compounds (47, 48) were identified. From A. tatarica six compounds, threeflavonoid glycosides (49-51) and three triterpene saponins of an oleanane type (52-54)were isolated. An oxygenated monoterpene (55) was isolated from Artemisiasantonicum essential oil...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita",
url = "https://hdl.handle.net/21.15107/rcub_nardus_11672"
}

Stanković, J.. (2019). Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_11672

Stanković J. Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita. in Универзитет у Београду. 2019;.
https://hdl.handle.net/21.15107/rcub_nardus_11672 .

Stanković, Jovana, "Halofitne biljne vrste - izolovanje i karakterizacija sekundarnih metabolita" in Универзитет у Београду (2019),
https://hdl.handle.net/21.15107/rcub_nardus_11672 .

TY  - JOUR
AU  - Stanković, Jovana
AU  - Novaković, Miroslav
AU  - Tešević, Vele
AU  - Ćiric, Ana
AU  - Soković, Marina
AU  - Zdunić, Gordana
AU  - Dajić-Stevanović, Zora
AU  - Gođevac, Dejan
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3433
AB  - This study was performed to determine the main antibacterial compounds of the essential oil (ЕО) of saltmarsh plant Artemisia santonicum (Asteraceae). The combination of HPTLC and direct bioautography was used for the activity guided isolation of isogeranic acid as the main antibacterial constituent with remarkable antimicrobial activity, although it was the minor component of the EO, present only in 0.2 %, as calculated from GC/FID. Its structure was determined by 1D- and 2D-NMR and GC–MS techniques. Antibacterial activity of isogeranic acid against all tested bacteria was significantly higher than EO and even than both controls streptomycin and ampicillin. In further investigation of antibiofilm and antiquorum sensing activity EO exhibited the best inhibition of the biofilm formation at 1/8 minimal inhibitory concentration (MIC) and isogeranic acid at 1/2 MIC. Both EO and isogeranic acid possessed pyocyanin inhibitory activity showing the reduction of pigment at 60.6 and 62.8 %, respectively, at 1/2 MIC concentrations.
AB  - Ово истраживање је спроведено у циљу одређивања главних антибактеријских компоненти етарског уља слатинске биљне врсте Artemisia santonicum (Asteraceae). Комбинација HPTLC методе и методе директне биоаутографије је коришћена за активношћу вођено изоловање изогеранилне киселине као главне компоненте са значајном антимикробном, антибиофилм и антикворум активношћу иако је била присутна у етарском уљу са само 0,2 %, израчунато из GC/FID. Њена структура је одређена 1D и 2D NMR и GC–MS техникама. Антибактеријска активност изогеранилне киселине на све тестиране бактерије је била значајно боља од етарског уља, и од обе контроле, стрептомицина и ампицилина. Етарско уље је показало најбољу инхибицију формирања биофилма у концентрацији 1/8 минималне инфибиторске концнетрације (MIC вредности), а изогеранилна киселина у концентрацији 1/2 MIC вредности. И етарско уље и изогеранилна киселина су имале пиоцијанин инхибиторну активност показавши смањење пигмента на 60,6 и 62,8 %, у концентрацији 1/2 MIC вредности, редом.
PB  - Serbian Chemical Society: Belgrade
T2  - Journal of the Serbian Chemical Society
T1  - HPTLC-direct bioautography-guided isolation of isogeranic acid as the main antibacterial constituent of Artemisia santonicum essential oil
T1  - HPTLC директно-биоаутографски вођено изоловање изогеранилне киселине као главне антибактеријске компоненте етарског уља
VL  - 84
IS  - 12
SP  - 1355
EP  - 1365
DO  - 10.2298/JSC190513106S
ER  - 

@article{
author = "Stanković, Jovana and Novaković, Miroslav and Tešević, Vele and Ćiric, Ana and Soković, Marina and Zdunić, Gordana and Dajić-Stevanović, Zora and Gođevac, Dejan",
year = "2019",
abstract = "This study was performed to determine the main antibacterial compounds of the essential oil (ЕО) of saltmarsh plant Artemisia santonicum (Asteraceae). The combination of HPTLC and direct bioautography was used for the activity guided isolation of isogeranic acid as the main antibacterial constituent with remarkable antimicrobial activity, although it was the minor component of the EO, present only in 0.2 %, as calculated from GC/FID. Its structure was determined by 1D- and 2D-NMR and GC–MS techniques. Antibacterial activity of isogeranic acid against all tested bacteria was significantly higher than EO and even than both controls streptomycin and ampicillin. In further investigation of antibiofilm and antiquorum sensing activity EO exhibited the best inhibition of the biofilm formation at 1/8 minimal inhibitory concentration (MIC) and isogeranic acid at 1/2 MIC. Both EO and isogeranic acid possessed pyocyanin inhibitory activity showing the reduction of pigment at 60.6 and 62.8 %, respectively, at 1/2 MIC concentrations., Ово истраживање је спроведено у циљу одређивања главних антибактеријских компоненти етарског уља слатинске биљне врсте Artemisia santonicum (Asteraceae). Комбинација HPTLC методе и методе директне биоаутографије је коришћена за активношћу вођено изоловање изогеранилне киселине као главне компоненте са значајном антимикробном, антибиофилм и антикворум активношћу иако је била присутна у етарском уљу са само 0,2 %, израчунато из GC/FID. Њена структура је одређена 1D и 2D NMR и GC–MS техникама. Антибактеријска активност изогеранилне киселине на све тестиране бактерије је била значајно боља од етарског уља, и од обе контроле, стрептомицина и ампицилина. Етарско уље је показало најбољу инхибицију формирања биофилма у концентрацији 1/8 минималне инфибиторске концнетрације (MIC вредности), а изогеранилна киселина у концентрацији 1/2 MIC вредности. И етарско уље и изогеранилна киселина су имале пиоцијанин инхибиторну активност показавши смањење пигмента на 60,6 и 62,8 %, у концентрацији 1/2 MIC вредности, редом.",
publisher = "Serbian Chemical Society: Belgrade",
journal = "Journal of the Serbian Chemical Society",
title = "HPTLC-direct bioautography-guided isolation of isogeranic acid as the main antibacterial constituent of Artemisia santonicum essential oil, HPTLC директно-биоаутографски вођено изоловање изогеранилне киселине као главне антибактеријске компоненте етарског уља",
volume = "84",
number = "12",
pages = "1355-1365",
doi = "10.2298/JSC190513106S"
}

Stanković, J., Novaković, M., Tešević, V., Ćiric, A., Soković, M., Zdunić, G., Dajić-Stevanović, Z.,& Gođevac, D.. (2019). HPTLC-direct bioautography-guided isolation of isogeranic acid as the main antibacterial constituent of Artemisia santonicum essential oil. in Journal of the Serbian Chemical Society
Serbian Chemical Society: Belgrade., 84(12), 1355-1365.
https://doi.org/10.2298/JSC190513106S

Stanković J, Novaković M, Tešević V, Ćiric A, Soković M, Zdunić G, Dajić-Stevanović Z, Gođevac D. HPTLC-direct bioautography-guided isolation of isogeranic acid as the main antibacterial constituent of Artemisia santonicum essential oil. in Journal of the Serbian Chemical Society. 2019;84(12):1355-1365.
doi:10.2298/JSC190513106S .

Stanković, Jovana, Novaković, Miroslav, Tešević, Vele, Ćiric, Ana, Soković, Marina, Zdunić, Gordana, Dajić-Stevanović, Zora, Gođevac, Dejan, "HPTLC-direct bioautography-guided isolation of isogeranic acid as the main antibacterial constituent of Artemisia santonicum essential oil" in Journal of the Serbian Chemical Society, 84, no. 12 (2019):1355-1365,
https://doi.org/10.2298/JSC190513106S . .

TY  - JOUR
AU  - Stanković, Jovana
AU  - Gođevac, Dejan
AU  - Tešević, Vele
AU  - Dajić-Stevanović, Zora
AU  - Ćirić, Ana
AU  - Soković, Marina
AU  - Novaković, Miroslav
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2995
AB  - A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-D-glucuronopyranosyl-(1→2)-β-Dglucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-Dglucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-L arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-D-glucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-L-arabinopyranoside)-30-hydroxyolean-12-en-
28-oate (3), named atriplexogenin II, and β-D-glucopyranosyl-3-O-(β-D-glucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→2)-α-L-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (5) and patuletin 3-O-5‴-Oferuloyl-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant
antibacterial activity, while the most potent antibiofilm agent is compound 2.
PB  - American Chemical Society (ACS)
T2  - Journal of Natural Products
T1  - Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa
VL  - 82
SP  - 1487
EP  - 1495
DO  - 10.1021/acs.jnatprod.8b00970
ER  - 

@article{
author = "Stanković, Jovana and Gođevac, Dejan and Tešević, Vele and Dajić-Stevanović, Zora and Ćirić, Ana and Soković, Marina and Novaković, Miroslav",
year = "2019",
abstract = "A new flavonoid glucoside derivative, patuletin 3-O-(2-O-feruloyl)-β-D-glucuronopyranosyl-(1→2)-β-Dglucopyranoside, named atriplexin IV (1), and three new triterpenoid saponin derivatives, two sulfonylated, β-Dglucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-L arabinopyranoside-30-alolean-12-en-28-oate (2), named atriplexogenin I, β-D-glucopyranosyl-3-O-(2-O-sulfo-β-D-galactopyranosyl)-(1→2)-α-L-arabinopyranoside)-30-hydroxyolean-12-en-
28-oate (3), named atriplexogenin II, and β-D-glucopyranosyl-3-O-(β-D-glucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→2)-α-L-arabinopyranoside)-30-alolean-12-en-28-oate (4), named atriplexogenin III, were isolated by silica gel column and semipreparative HPLC chromatography from the n-butanol extract of the salt marsh plant Atriplex tatarica. In addition, two known secondary metabolites, patuletin3-O-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (5) and patuletin 3-O-5‴-Oferuloyl-β-D-apiofuranosyl-(1‴→2″)-β-D-glucopyranoside (6), were isolated for the first time from A. tatarica. The structures of the isolated compounds were elucidated by 1D and 2D NMR, HRESIMS, IR, and UV data. Antibacterial activity by the microdilution method and antibiofilm activity against P. aeruginosa were assessed. Compound 5 possesses significant
antibacterial activity, while the most potent antibiofilm agent is compound 2.",
publisher = "American Chemical Society (ACS)",
journal = "Journal of Natural Products",
title = "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa",
volume = "82",
pages = "1487-1495",
doi = "10.1021/acs.jnatprod.8b00970"
}

Stanković, J., Gođevac, D., Tešević, V., Dajić-Stevanović, Z., Ćirić, A., Soković, M.,& Novaković, M.. (2019). Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products
American Chemical Society (ACS)., 82, 1487-1495.
https://doi.org/10.1021/acs.jnatprod.8b00970

Stanković J, Gođevac D, Tešević V, Dajić-Stevanović Z, Ćirić A, Soković M, Novaković M. Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. in Journal of Natural Products. 2019;82:1487-1495.
doi:10.1021/acs.jnatprod.8b00970 .

Stanković, Jovana, Gođevac, Dejan, Tešević, Vele, Dajić-Stevanović, Zora, Ćirić, Ana, Soković, Marina, Novaković, Miroslav, "Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa" in Journal of Natural Products, 82 (2019):1487-1495,
https://doi.org/10.1021/acs.jnatprod.8b00970 . .

TY  - JOUR
AU  - Ljekočević, Marko
AU  - Jadranin, Milka
AU  - Stanković, Jovana
AU  - Popović, Branko
AU  - Nikićević, Ninoslav
AU  - Petrović, Aleksandar
AU  - Tešević, Vele
PY  - 2019
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2924
AB  - Plum wines made from two cultivars of Prunus domestica L. (Požegača and Crvena ranka) and one cultivar of Prunus insititia L. (Trnovača) were evaluated for their total phenolic and anthocyanin contents. LC–MS/MS analysis based on specific MS transitions in the multiple reaction monitoring (MRM) mode was used for the identification and quantification of selected phenolic compounds. Catechin, chlorogenic and caffeic acids, as well as quercetin, were identified as the main polyphenols in plum wines. The total amount of phenolic compounds ranged from 1.24 to 1.58 g gallic acid equivalent per L. Among the examined wines, the Crvena ranka wine had a higher content of anthocyanins (12.31 mg cyanidin-3-glucoside equivalent per L). The antioxidant capacity of the wines was determined using the DPPH assay. The variations in the physicochemical characteristics, phenolic composition and DPPH radical scavenging activity of these wines are related to differences due to the different plum cultivars used in the preparation of each wine
T2  - Journal of the Serbian Chemical Society
T1  - Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars
VL  - 84
IS  - 2
SP  - 141
EP  - 151
DO  - 10.2298/JSC180710096L
ER  - 

@article{
author = "Ljekočević, Marko and Jadranin, Milka and Stanković, Jovana and Popović, Branko and Nikićević, Ninoslav and Petrović, Aleksandar and Tešević, Vele",
year = "2019",
abstract = "Plum wines made from two cultivars of Prunus domestica L. (Požegača and Crvena ranka) and one cultivar of Prunus insititia L. (Trnovača) were evaluated for their total phenolic and anthocyanin contents. LC–MS/MS analysis based on specific MS transitions in the multiple reaction monitoring (MRM) mode was used for the identification and quantification of selected phenolic compounds. Catechin, chlorogenic and caffeic acids, as well as quercetin, were identified as the main polyphenols in plum wines. The total amount of phenolic compounds ranged from 1.24 to 1.58 g gallic acid equivalent per L. Among the examined wines, the Crvena ranka wine had a higher content of anthocyanins (12.31 mg cyanidin-3-glucoside equivalent per L). The antioxidant capacity of the wines was determined using the DPPH assay. The variations in the physicochemical characteristics, phenolic composition and DPPH radical scavenging activity of these wines are related to differences due to the different plum cultivars used in the preparation of each wine",
journal = "Journal of the Serbian Chemical Society",
title = "Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars",
volume = "84",
number = "2",
pages = "141-151",
doi = "10.2298/JSC180710096L"
}

Ljekočević, M., Jadranin, M., Stanković, J., Popović, B., Nikićević, N., Petrović, A.,& Tešević, V.. (2019). Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars. in Journal of the Serbian Chemical Society, 84(2), 141-151.
https://doi.org/10.2298/JSC180710096L

Ljekočević M, Jadranin M, Stanković J, Popović B, Nikićević N, Petrović A, Tešević V. Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars. in Journal of the Serbian Chemical Society. 2019;84(2):141-151.
doi:10.2298/JSC180710096L .

Ljekočević, Marko, Jadranin, Milka, Stanković, Jovana, Popović, Branko, Nikićević, Ninoslav, Petrović, Aleksandar, Tešević, Vele, "Phenolic composition and DPPH radical scavenging activity of plum wine produced from three plum cultivars" in Journal of the Serbian Chemical Society, 84, no. 2 (2019):141-151,
https://doi.org/10.2298/JSC180710096L . .

TY  - CONF
AU  - Stupar, Sofija
AU  - Tešević, Vele
AU  - Stanković, Jovana
AU  - Ćosić, Tatjana
AU  - Devrnja, Nina
AU  - Tubić, Ljiljana
AU  - Cingel, Aleksandar
AU  - Ninković, Slavica
AU  - Vinterhalter, Branka
AU  - Savić, Jelena
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7514
AB  - When attacked, plants activate defense mechanisms including volatile emission. Besides havinga pest repellent effect, volatiles can induce defense response in surrounding unharmed plants.French marigold (Tagetes patula L.) essential oil (EO) was isolated from the above-ground partsof plants collected from nature by hydrodistillation using Clevenger apparatus. GC/MS analysisrevealed the presence of 42 compounds, of which 97% (32 compounds) have been identified.The monoterpene fraction was dominant (76.9%) with terpinolene (32.4%) and limonene (14.7%)as the most abundant compounds. In order to investigate the potential of marigold EO to inducethe defense of potato, we analyzed 3 genes related to the induced resistance (IR): pathogenesisrelated PR-2 and PR-5 genes, and proteinase inhibitor Pin2. The potato plants were exposed to EOvolatiles during 4, 8 and 12 h. Two leaves of EO-treated or untreated control plants were collected,and plants were then additionally injured by mechanically wounding leaves across the leaf surface.After 24 h of wounding, another two leaves from each plant were collected and expressionof the IR related genes was analyzed by qPCR method. EO induced altered expression of PR genes,while Pin2 wasn’t affected by the treatment. Mechanical wounding increased the expression ofall genes after 4 and 8 h of EO treatment, with up to 4-fold change in PR-2. However, in plantsexposed to EO for 12 h before wounding, the level of transcription in PR-2 and Pin2 was similar tothat detected in untreated controls. These findings support the efforts for environmentally-safepest control in crops by using natural compounds.
PB  - Belgrade: Serbian Plant Physiology Society
C3  - 3rd International Conference on Plant Biology and 22nd Symposium of the Serbian Plant Physiology Society, Belgrade, Serbia, Book of abstracts
T1  - Induction of potato (Solanum tuberosum L.) defense genes by French marigold (Tagetes patula L.) essential oil
SP  - 58
EP  - 58
UR  - https://hdl.handle.net/21.15107/rcub_cer_7514
ER  - 

@conference{
author = "Stupar, Sofija and Tešević, Vele and Stanković, Jovana and Ćosić, Tatjana and Devrnja, Nina and Tubić, Ljiljana and Cingel, Aleksandar and Ninković, Slavica and Vinterhalter, Branka and Savić, Jelena",
year = "2018",
abstract = "When attacked, plants activate defense mechanisms including volatile emission. Besides havinga pest repellent effect, volatiles can induce defense response in surrounding unharmed plants.French marigold (Tagetes patula L.) essential oil (EO) was isolated from the above-ground partsof plants collected from nature by hydrodistillation using Clevenger apparatus. GC/MS analysisrevealed the presence of 42 compounds, of which 97% (32 compounds) have been identified.The monoterpene fraction was dominant (76.9%) with terpinolene (32.4%) and limonene (14.7%)as the most abundant compounds. In order to investigate the potential of marigold EO to inducethe defense of potato, we analyzed 3 genes related to the induced resistance (IR): pathogenesisrelated PR-2 and PR-5 genes, and proteinase inhibitor Pin2. The potato plants were exposed to EOvolatiles during 4, 8 and 12 h. Two leaves of EO-treated or untreated control plants were collected,and plants were then additionally injured by mechanically wounding leaves across the leaf surface.After 24 h of wounding, another two leaves from each plant were collected and expressionof the IR related genes was analyzed by qPCR method. EO induced altered expression of PR genes,while Pin2 wasn’t affected by the treatment. Mechanical wounding increased the expression ofall genes after 4 and 8 h of EO treatment, with up to 4-fold change in PR-2. However, in plantsexposed to EO for 12 h before wounding, the level of transcription in PR-2 and Pin2 was similar tothat detected in untreated controls. These findings support the efforts for environmentally-safepest control in crops by using natural compounds.",
publisher = "Belgrade: Serbian Plant Physiology Society",
journal = "3rd International Conference on Plant Biology and 22nd Symposium of the Serbian Plant Physiology Society, Belgrade, Serbia, Book of abstracts",
title = "Induction of potato (Solanum tuberosum L.) defense genes by French marigold (Tagetes patula L.) essential oil",
pages = "58-58",
url = "https://hdl.handle.net/21.15107/rcub_cer_7514"
}

Stupar, S., Tešević, V., Stanković, J., Ćosić, T., Devrnja, N., Tubić, L., Cingel, A., Ninković, S., Vinterhalter, B.,& Savić, J.. (2018). Induction of potato (Solanum tuberosum L.) defense genes by French marigold (Tagetes patula L.) essential oil. in 3rd International Conference on Plant Biology and 22nd Symposium of the Serbian Plant Physiology Society, Belgrade, Serbia, Book of abstracts
Belgrade: Serbian Plant Physiology Society., 58-58.
https://hdl.handle.net/21.15107/rcub_cer_7514

Stupar S, Tešević V, Stanković J, Ćosić T, Devrnja N, Tubić L, Cingel A, Ninković S, Vinterhalter B, Savić J. Induction of potato (Solanum tuberosum L.) defense genes by French marigold (Tagetes patula L.) essential oil. in 3rd International Conference on Plant Biology and 22nd Symposium of the Serbian Plant Physiology Society, Belgrade, Serbia, Book of abstracts. 2018;:58-58.
https://hdl.handle.net/21.15107/rcub_cer_7514 .

Stupar, Sofija, Tešević, Vele, Stanković, Jovana, Ćosić, Tatjana, Devrnja, Nina, Tubić, Ljiljana, Cingel, Aleksandar, Ninković, Slavica, Vinterhalter, Branka, Savić, Jelena, "Induction of potato (Solanum tuberosum L.) defense genes by French marigold (Tagetes patula L.) essential oil" in 3rd International Conference on Plant Biology and 22nd Symposium of the Serbian Plant Physiology Society, Belgrade, Serbia, Book of abstracts (2018):58-58,
https://hdl.handle.net/21.15107/rcub_cer_7514 .

TY  - JOUR
AU  - Paykovic-Lucic, S.
AU  - Todosijević, Marina
AU  - Savić, Tatjana T.
AU  - Trajković, Jelena
AU  - Cvetković, Mirjana
AU  - Stanković, Jovana
AU  - Miličić, Dragana M.
AU  - Lučić, Luka
AU  - Tornic, Vladimir T.
AU  - Makarov, Slobodan E.
AU  - Vujisić, Ljubodrag V.
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2356
AB  - In insects, cuticular hydrocarbon (CHC) profile is involved in many important biological functions and may vary in different conditions. Among fruit fly species, Drosophila subobscura is one of the most frequently used in genetic, ecological and evolutionary research, because of its rich chromosomal polymorphism, specific behavioral repertoires and habitat preferences. In this work, we identified and quantified cuticular chemoprofile of D. subobscura. Using gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC-MS), 25 chemical compounds were found in males and 23 compounds were found in females. Further, ANOVA confirmed significant sexual dimorphism in cuticular chemoprofile amounts. Knowledge of cuticular chemistry could contribute to further research in D. subobscura, starting from behavioral, up to ecological, since this species is recognized as an important model system for the study and monitoring of global climate changes.
PB  - Pakistan Agricultural Scientists Forum
T2  - Journal of Animal and Plant Sciences
T1  - Cuticular chemoprofile of the fruit fly drosophila subobscura (diptera, drosophilidae)
VL  - 28
IS  - 6
SP  - 1881
EP  - 1886
UR  - https://hdl.handle.net/21.15107/rcub_cer_2356
ER  - 

@article{
author = "Paykovic-Lucic, S. and Todosijević, Marina and Savić, Tatjana T. and Trajković, Jelena and Cvetković, Mirjana and Stanković, Jovana and Miličić, Dragana M. and Lučić, Luka and Tornic, Vladimir T. and Makarov, Slobodan E. and Vujisić, Ljubodrag V.",
year = "2018",
abstract = "In insects, cuticular hydrocarbon (CHC) profile is involved in many important biological functions and may vary in different conditions. Among fruit fly species, Drosophila subobscura is one of the most frequently used in genetic, ecological and evolutionary research, because of its rich chromosomal polymorphism, specific behavioral repertoires and habitat preferences. In this work, we identified and quantified cuticular chemoprofile of D. subobscura. Using gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC-MS), 25 chemical compounds were found in males and 23 compounds were found in females. Further, ANOVA confirmed significant sexual dimorphism in cuticular chemoprofile amounts. Knowledge of cuticular chemistry could contribute to further research in D. subobscura, starting from behavioral, up to ecological, since this species is recognized as an important model system for the study and monitoring of global climate changes.",
publisher = "Pakistan Agricultural Scientists Forum",
journal = "Journal of Animal and Plant Sciences",
title = "Cuticular chemoprofile of the fruit fly drosophila subobscura (diptera, drosophilidae)",
volume = "28",
number = "6",
pages = "1881-1886",
url = "https://hdl.handle.net/21.15107/rcub_cer_2356"
}

Paykovic-Lucic, S., Todosijević, M., Savić, T. T., Trajković, J., Cvetković, M., Stanković, J., Miličić, D. M., Lučić, L., Tornic, V. T., Makarov, S. E.,& Vujisić, L. V.. (2018). Cuticular chemoprofile of the fruit fly drosophila subobscura (diptera, drosophilidae). in Journal of Animal and Plant Sciences
Pakistan Agricultural Scientists Forum., 28(6), 1881-1886.
https://hdl.handle.net/21.15107/rcub_cer_2356

Paykovic-Lucic S, Todosijević M, Savić TT, Trajković J, Cvetković M, Stanković J, Miličić DM, Lučić L, Tornic VT, Makarov SE, Vujisić LV. Cuticular chemoprofile of the fruit fly drosophila subobscura (diptera, drosophilidae). in Journal of Animal and Plant Sciences. 2018;28(6):1881-1886.
https://hdl.handle.net/21.15107/rcub_cer_2356 .

Paykovic-Lucic, S., Todosijević, Marina, Savić, Tatjana T., Trajković, Jelena, Cvetković, Mirjana, Stanković, Jovana, Miličić, Dragana M., Lučić, Luka, Tornic, Vladimir T., Makarov, Slobodan E., Vujisić, Ljubodrag V., "Cuticular chemoprofile of the fruit fly drosophila subobscura (diptera, drosophilidae)" in Journal of Animal and Plant Sciences, 28, no. 6 (2018):1881-1886,
https://hdl.handle.net/21.15107/rcub_cer_2356 .

TY  - JOUR
AU  - Nikolić, Biljana
AU  - Matovic, Milie
AU  - Todosijević, Marina
AU  - Stanković, Jovana
AU  - Cvetković, Mirjana
AU  - Marin, Petar D.
AU  - Tešević, Vele
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2439
AB  - Terpene compounds of Tanacetum macrophyllum as 1) essential oils, obtained by hydrodistillation (HD), 2) essential oil extracts, obtained by simultaneous' hydrodistillation and extraction (SDE) and 3) volatiles, obtained by Static Headspace GC-MS analysis (HS) were processed. Monoterpenes were the most dominant (49.2%, 49.5% and 90.4%, respectively). Profiles of essential oils obtained by HD and SD were quite similar, with oxygenated monoterpenes (39.3% and 39.4%) being the most abundant. In HS volatiles oxygenated monoterpenes also dominated (57.4%). Total sesquiterpenes were abundant in HD and SDE volatiles (38.2% and 39.2%, resp.), where sesquiterpene hydrocarbons were prevalent (27.3% and 28.7%, resp.). Germacrene D was dominant in HD and SDE oils (22.0% and 23.3%, resp.) and 1,8-cineole in HS volatiles (34.3%). To our knowledge, this is the first use of Headspace technique on T macrophyllum. Furthermore, this is the first comparison of different techniques of volatile extraction in T. macrophyllum.
PB  - Natural Products Inc, Westerville
T2  - Natural Product Communications
T1  - Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods
VL  - 13
IS  - 7
SP  - 891
EP  - 893
UR  - https://hdl.handle.net/21.15107/rcub_cer_2439
ER  - 

@article{
author = "Nikolić, Biljana and Matovic, Milie and Todosijević, Marina and Stanković, Jovana and Cvetković, Mirjana and Marin, Petar D. and Tešević, Vele",
year = "2018",
abstract = "Terpene compounds of Tanacetum macrophyllum as 1) essential oils, obtained by hydrodistillation (HD), 2) essential oil extracts, obtained by simultaneous' hydrodistillation and extraction (SDE) and 3) volatiles, obtained by Static Headspace GC-MS analysis (HS) were processed. Monoterpenes were the most dominant (49.2%, 49.5% and 90.4%, respectively). Profiles of essential oils obtained by HD and SD were quite similar, with oxygenated monoterpenes (39.3% and 39.4%) being the most abundant. In HS volatiles oxygenated monoterpenes also dominated (57.4%). Total sesquiterpenes were abundant in HD and SDE volatiles (38.2% and 39.2%, resp.), where sesquiterpene hydrocarbons were prevalent (27.3% and 28.7%, resp.). Germacrene D was dominant in HD and SDE oils (22.0% and 23.3%, resp.) and 1,8-cineole in HS volatiles (34.3%). To our knowledge, this is the first use of Headspace technique on T macrophyllum. Furthermore, this is the first comparison of different techniques of volatile extraction in T. macrophyllum.",
publisher = "Natural Products Inc, Westerville",
journal = "Natural Product Communications",
title = "Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods",
volume = "13",
number = "7",
pages = "891-893",
url = "https://hdl.handle.net/21.15107/rcub_cer_2439"
}

Nikolić, B., Matovic, M., Todosijević, M., Stanković, J., Cvetković, M., Marin, P. D.,& Tešević, V.. (2018). Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods. in Natural Product Communications
Natural Products Inc, Westerville., 13(7), 891-893.
https://hdl.handle.net/21.15107/rcub_cer_2439

Nikolić B, Matovic M, Todosijević M, Stanković J, Cvetković M, Marin PD, Tešević V. Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods. in Natural Product Communications. 2018;13(7):891-893.
https://hdl.handle.net/21.15107/rcub_cer_2439 .

Nikolić, Biljana, Matovic, Milie, Todosijević, Marina, Stanković, Jovana, Cvetković, Mirjana, Marin, Petar D., Tešević, Vele, "Volatiles of Tanacetum macrophyllum Obtained by Different Extraction Methods" in Natural Product Communications, 13, no. 7 (2018):891-893,
https://hdl.handle.net/21.15107/rcub_cer_2439 .