TY  - JOUR
AU  - Milenković, Mila
AU  - Ciasca, Gabriele
AU  - Bonasera, Aurelio
AU  - Scopelliti, Michelangelo
AU  - Marković, Olivera
AU  - Verbić, Tatjana
AU  - Todorović Marković, Biljana
AU  - Jovanović, Svetlana
PY  - 2024
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7093
AB  - The widespread abuse of traditional antibiotics has led to a global rise in antibiotic-resistant bacteria, which give in return unprecedented health risks. Therefore, there is a large and urgent need for the development of new, smart antibacterial agents able to efficiently kill or inhibit bacterial growth. In this study, we investigated the antibacterial activity of S, N-doped Graphene Quantum Dots (GQDs) as a light-triggered antibacterial agent. Gamma irradiation was employed as a tool to achieve one-step modification of GQDs in the presence of L-cysteine amino acid as a source of heteroatoms. X-ray Photoelectron Spectroscopy (XPS), nuclear magnetic 
resonance (NMR), and zeta potential measurements provided the necessary data to clarify the structure of modified dots and verify the introduction of both S- and N-atoms in GQDs structure, but also severe changes in the aromatic, sp2 domains. Namely, γ-irradiation caused a bonding of S atoms in 1.14 at.% mainly as thiol groups, and N in 1.81 at.% as amino groups, but sp2 contribution in GQD structure was lowered from 63.00 to 4.86 at.%, as measured in dots irradiated at a dose of 200 kGy. Fluorescence quenching measurements showed that L-cysteine-modified dots are able to bind to human serum albumin. The antibacterial activity of GQDs 
combined with 1 and 6 h of blue light (470 nm) irradiation was tested against 8 bacterial strains. GQD-cys-25 sample provided the best results, with minimum inhibitory concentration (MIC) as low as 125 μg/mL against S. aureus, E. faecalis, and E. coli after only 1 h of blue light exposure.
PB  - Elsevier
T2  - Journal of Photochemistry and Photobiology, B: Biology
T1  - Blue-light-driven photoactivity of L-cysteine-modified graphene quantum  dots and their antibacterial effects
VL  - 250
SP  - 112818
DO  - 10.1016/j.jphotobiol.2023.112818
ER  - 

@article{
author = "Milenković, Mila and Ciasca, Gabriele and Bonasera, Aurelio and Scopelliti, Michelangelo and Marković, Olivera and Verbić, Tatjana and Todorović Marković, Biljana and Jovanović, Svetlana",
year = "2024",
abstract = "The widespread abuse of traditional antibiotics has led to a global rise in antibiotic-resistant bacteria, which give in return unprecedented health risks. Therefore, there is a large and urgent need for the development of new, smart antibacterial agents able to efficiently kill or inhibit bacterial growth. In this study, we investigated the antibacterial activity of S, N-doped Graphene Quantum Dots (GQDs) as a light-triggered antibacterial agent. Gamma irradiation was employed as a tool to achieve one-step modification of GQDs in the presence of L-cysteine amino acid as a source of heteroatoms. X-ray Photoelectron Spectroscopy (XPS), nuclear magnetic 
resonance (NMR), and zeta potential measurements provided the necessary data to clarify the structure of modified dots and verify the introduction of both S- and N-atoms in GQDs structure, but also severe changes in the aromatic, sp2 domains. Namely, γ-irradiation caused a bonding of S atoms in 1.14 at.% mainly as thiol groups, and N in 1.81 at.% as amino groups, but sp2 contribution in GQD structure was lowered from 63.00 to 4.86 at.%, as measured in dots irradiated at a dose of 200 kGy. Fluorescence quenching measurements showed that L-cysteine-modified dots are able to bind to human serum albumin. The antibacterial activity of GQDs 
combined with 1 and 6 h of blue light (470 nm) irradiation was tested against 8 bacterial strains. GQD-cys-25 sample provided the best results, with minimum inhibitory concentration (MIC) as low as 125 μg/mL against S. aureus, E. faecalis, and E. coli after only 1 h of blue light exposure.",
publisher = "Elsevier",
journal = "Journal of Photochemistry and Photobiology, B: Biology",
title = "Blue-light-driven photoactivity of L-cysteine-modified graphene quantum  dots and their antibacterial effects",
volume = "250",
pages = "112818",
doi = "10.1016/j.jphotobiol.2023.112818"
}

Milenković, M., Ciasca, G., Bonasera, A., Scopelliti, M., Marković, O., Verbić, T., Todorović Marković, B.,& Jovanović, S.. (2024). Blue-light-driven photoactivity of L-cysteine-modified graphene quantum  dots and their antibacterial effects. in Journal of Photochemistry and Photobiology, B: Biology
Elsevier., 250, 112818.
https://doi.org/10.1016/j.jphotobiol.2023.112818

Milenković M, Ciasca G, Bonasera A, Scopelliti M, Marković O, Verbić T, Todorović Marković B, Jovanović S. Blue-light-driven photoactivity of L-cysteine-modified graphene quantum  dots and their antibacterial effects. in Journal of Photochemistry and Photobiology, B: Biology. 2024;250:112818.
doi:10.1016/j.jphotobiol.2023.112818 .

Milenković, Mila, Ciasca, Gabriele, Bonasera, Aurelio, Scopelliti, Michelangelo, Marković, Olivera, Verbić, Tatjana, Todorović Marković, Biljana, Jovanović, Svetlana, "Blue-light-driven photoactivity of L-cysteine-modified graphene quantum  dots and their antibacterial effects" in Journal of Photochemistry and Photobiology, B: Biology, 250 (2024):112818,
https://doi.org/10.1016/j.jphotobiol.2023.112818 . .

TY  - JOUR
AU  - Krunić, Matija
AU  - Ristić, Biljana
AU  - Bošnjak, Mihajlo
AU  - Paunović, Verica
AU  - Tovilović-Kovačević, Gordana
AU  - Zogović, Nevena
AU  - Mirčić, Aleksandar
AU  - Marković, Zoran
AU  - Todorović-Marković, Biljana
AU  - Jovanović, Svetlana
AU  - Kleut, Duška
AU  - Mojović, Miloš
AU  - Nakarada, Đura
AU  - Marković, Olivera
AU  - Vuković, Irena
AU  - Harhaji-Trajković, Ljubica
AU  - Trajković, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4812
AB  - We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuroblastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP).
GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (•OH), superoxide anion (O2•- ), and lipid peroxidation. Nonselective antioxidants, •OH scavenging, and iron chelators, but not superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagylimiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proautophagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early (wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •OH/NO scavenging and induction of cytoprotective autophagy.
PB  - Elsevier
T2  - Free Radical Biology and Medicine
T1  - Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death
VL  - 177
SP  - 167
EP  - 180
DO  - 10.1016/j.freeradbiomed.2021.10.025
ER  - 

@article{
author = "Krunić, Matija and Ristić, Biljana and Bošnjak, Mihajlo and Paunović, Verica and Tovilović-Kovačević, Gordana and Zogović, Nevena and Mirčić, Aleksandar and Marković, Zoran and Todorović-Marković, Biljana and Jovanović, Svetlana and Kleut, Duška and Mojović, Miloš and Nakarada, Đura and Marković, Olivera and Vuković, Irena and Harhaji-Trajković, Ljubica and Trajković, Vladimir",
year = "2021",
abstract = "We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuroblastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP).
GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (•OH), superoxide anion (O2•- ), and lipid peroxidation. Nonselective antioxidants, •OH scavenging, and iron chelators, but not superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagylimiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proautophagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early (wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •OH/NO scavenging and induction of cytoprotective autophagy.",
publisher = "Elsevier",
journal = "Free Radical Biology and Medicine",
title = "Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death",
volume = "177",
pages = "167-180",
doi = "10.1016/j.freeradbiomed.2021.10.025"
}

Krunić, M., Ristić, B., Bošnjak, M., Paunović, V., Tovilović-Kovačević, G., Zogović, N., Mirčić, A., Marković, Z., Todorović-Marković, B., Jovanović, S., Kleut, D., Mojović, M., Nakarada, Đ., Marković, O., Vuković, I., Harhaji-Trajković, L.,& Trajković, V.. (2021). Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death. in Free Radical Biology and Medicine
Elsevier., 177, 167-180.
https://doi.org/10.1016/j.freeradbiomed.2021.10.025

Krunić M, Ristić B, Bošnjak M, Paunović V, Tovilović-Kovačević G, Zogović N, Mirčić A, Marković Z, Todorović-Marković B, Jovanović S, Kleut D, Mojović M, Nakarada Đ, Marković O, Vuković I, Harhaji-Trajković L, Trajković V. Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death. in Free Radical Biology and Medicine. 2021;177:167-180.
doi:10.1016/j.freeradbiomed.2021.10.025 .

Krunić, Matija, Ristić, Biljana, Bošnjak, Mihajlo, Paunović, Verica, Tovilović-Kovačević, Gordana, Zogović, Nevena, Mirčić, Aleksandar, Marković, Zoran, Todorović-Marković, Biljana, Jovanović, Svetlana, Kleut, Duška, Mojović, Miloš, Nakarada, Đura, Marković, Olivera, Vuković, Irena, Harhaji-Trajković, Ljubica, Trajković, Vladimir, "Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death" in Free Radical Biology and Medicine, 177 (2021):167-180,
https://doi.org/10.1016/j.freeradbiomed.2021.10.025 . .

TY  - JOUR
AU  - Krunić, Matija
AU  - Ristić, Biljana
AU  - Bošnjak, Mihajlo
AU  - Paunović, Verica
AU  - Tovilović-Kovačević, Gordana
AU  - Zogović, Nevena
AU  - Mirčić, Aleksandar
AU  - Marković, Zoran
AU  - Todorović-Marković, Biljana
AU  - Jovanović, Svetlana
AU  - Kleut, Duška
AU  - Mojović, Miloš
AU  - Nakarada, Đura
AU  - Marković, Olivera
AU  - Vuković, Irena
AU  - Harhaji-Trajković, Ljubica
AU  - Trajković, Vladimir
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4818
AB  - We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuroblastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP).GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (•OH), superoxide anion (O2•- ), and lipid peroxidation. Nonselective antioxidants, •OH scavenging, and iron chelators, but not superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagylimiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proautophagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early (wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •OH/NO scavenging and induction of cytoprotective autophagy.
PB  - Elsevier
T2  - Free Radical Biology and Medicine
T1  - Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death
VL  - 177
SP  - 167
EP  - 180
DO  - 10.1016/j.freeradbiomed.2021.10.025
ER  - 

@article{
author = "Krunić, Matija and Ristić, Biljana and Bošnjak, Mihajlo and Paunović, Verica and Tovilović-Kovačević, Gordana and Zogović, Nevena and Mirčić, Aleksandar and Marković, Zoran and Todorović-Marković, Biljana and Jovanović, Svetlana and Kleut, Duška and Mojović, Miloš and Nakarada, Đura and Marković, Olivera and Vuković, Irena and Harhaji-Trajković, Ljubica and Trajković, Vladimir",
year = "2021",
abstract = "We investigated the ability of graphene quantum dot (GQD) nanoparticles to protect SH-SY5Y human neuroblastoma cells from oxidative/nitrosative stress induced by iron-nitrosyl complex sodium nitroprusside (SNP).GQD reduced SNP cytotoxicity by preventing mitochondrial depolarization, caspase-2 activation, and subsequent apoptotic death. Although GQD diminished the levels of nitric oxide (NO) in SNP-exposed cells, NO scavengers displayed only a slight protective effect, suggesting that NO quenching was not the main protective mechanism of GQD. GQD also reduced SNP-triggered increase in the intracellular levels of hydroxyl radical (•OH), superoxide anion (O2•- ), and lipid peroxidation. Nonselective antioxidants, •OH scavenging, and iron chelators, but not superoxide dismutase, mimicked GQD cytoprotective activity, indicating that GQD protect cells by neutralizing •OH generated in the presence of SNP-released iron. Cellular internalization of GQD was required for optimal protection, since a removal of extracellular GQD by extensive washing only partly diminished their protective effect. Moreover, GQD cooperated with SNP to induce autophagy, as confirmed by the inhibition of autophagylimiting Akt/PRAS40/mTOR signaling and increase in autophagy gene transcription, protein levels of proautophagic beclin-1 and LC3-II, formation of autophagic vesicles, and degradation of autophagic target p62. The antioxidant activity of GQD was not involved in autophagy induction, as antioxidants N-acetylcysteine and dimethyl sulfoxide failed to stimulate autophagy in SNP-exposed cells. Pharmacological inhibitors of early (wortmannin, 3-methyladenine) or late stages of autophagy (NH4Cl) efficiently reduced the protective effect of GQD. Therefore, the ability of GQD to prevent the in vitro neurotoxicity of SNP depends on both •OH/NO scavenging and induction of cytoprotective autophagy.",
publisher = "Elsevier",
journal = "Free Radical Biology and Medicine",
title = "Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death",
volume = "177",
pages = "167-180",
doi = "10.1016/j.freeradbiomed.2021.10.025"
}

Krunić, M., Ristić, B., Bošnjak, M., Paunović, V., Tovilović-Kovačević, G., Zogović, N., Mirčić, A., Marković, Z., Todorović-Marković, B., Jovanović, S., Kleut, D., Mojović, M., Nakarada, Đ., Marković, O., Vuković, I., Harhaji-Trajković, L.,& Trajković, V.. (2021). Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death. in Free Radical Biology and Medicine
Elsevier., 177, 167-180.
https://doi.org/10.1016/j.freeradbiomed.2021.10.025

Krunić M, Ristić B, Bošnjak M, Paunović V, Tovilović-Kovačević G, Zogović N, Mirčić A, Marković Z, Todorović-Marković B, Jovanović S, Kleut D, Mojović M, Nakarada Đ, Marković O, Vuković I, Harhaji-Trajković L, Trajković V. Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death. in Free Radical Biology and Medicine. 2021;177:167-180.
doi:10.1016/j.freeradbiomed.2021.10.025 .

Krunić, Matija, Ristić, Biljana, Bošnjak, Mihajlo, Paunović, Verica, Tovilović-Kovačević, Gordana, Zogović, Nevena, Mirčić, Aleksandar, Marković, Zoran, Todorović-Marković, Biljana, Jovanović, Svetlana, Kleut, Duška, Mojović, Miloš, Nakarada, Đura, Marković, Olivera, Vuković, Irena, Harhaji-Trajković, Ljubica, Trajković, Vladimir, "Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death" in Free Radical Biology and Medicine, 177 (2021):167-180,
https://doi.org/10.1016/j.freeradbiomed.2021.10.025 . .

TY  - JOUR
AU  - Jovanović, Svetlana
AU  - Dorontić, Slađana
AU  - Jovanović, Dragana
AU  - Ciasca, Gabriele
AU  - Budimir, Milica
AU  - Bonasera, Aurelio
AU  - Scopelliti, Michelangelo
AU  - Marković, Olivera
AU  - Todorović Marković, Biljana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3593
AB  - Due to the low consumption of chemicals, the absence of toxic residual side products, the procedure simplicity and time-saving aspects, gamma irradiation offers advantages over the classical chemical protocols. We successfully employed gamma irradiation in order to introduce N-atoms in Graphene Quantum Dots (GQDs). By irradiating GQDs water dispersions in the presence of isopropyl alcohol and ethylenediamine, at doses of 25, 50 and 200 kGy, we attached amino groups onto GQDs in a single synthetic step. At the same time, a chemical reduction is achieved, too. Selected conditions induced incorporation of N-atoms within GDQs atomic lattice (around 3 at%), at all applied doses. Additionally, the C-atoms percentage was highly increased, from 63 to 79 at % or higher. The zeta potential of dots changed from −34.6 to +9.1 mV, due to the modification of functionalizing groups localized at the surface. Produced chemical changes lead to the desired alteration of the GQDs optical properties, such as an increased photoluminescence intensity, a higher photoluminescence quantum yields (from 2.07 to 18.40%) and a narrowing of the spectral features in the emission spectra. The ability of gamma-irradiated GQDs to quench free radical species was investigated and positively assessed; additionally, non-enzymatic optical detection of Cu(II) ions using GQDs as a sensor was studied and the detection limits are
herein reported. These results suggest that GQDs can be potentially applied as smart photoluminescent sensors for metal cations.
PB  - Elsevier
T2  - Ceramics International
T1  - Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing
VL  - 46
IS  - 15
SP  - 23611
EP  - 23622
DO  - 10.1016/j.ceramint.2020.06.133
ER  - 

@article{
author = "Jovanović, Svetlana and Dorontić, Slađana and Jovanović, Dragana and Ciasca, Gabriele and Budimir, Milica and Bonasera, Aurelio and Scopelliti, Michelangelo and Marković, Olivera and Todorović Marković, Biljana",
year = "2020",
abstract = "Due to the low consumption of chemicals, the absence of toxic residual side products, the procedure simplicity and time-saving aspects, gamma irradiation offers advantages over the classical chemical protocols. We successfully employed gamma irradiation in order to introduce N-atoms in Graphene Quantum Dots (GQDs). By irradiating GQDs water dispersions in the presence of isopropyl alcohol and ethylenediamine, at doses of 25, 50 and 200 kGy, we attached amino groups onto GQDs in a single synthetic step. At the same time, a chemical reduction is achieved, too. Selected conditions induced incorporation of N-atoms within GDQs atomic lattice (around 3 at%), at all applied doses. Additionally, the C-atoms percentage was highly increased, from 63 to 79 at % or higher. The zeta potential of dots changed from −34.6 to +9.1 mV, due to the modification of functionalizing groups localized at the surface. Produced chemical changes lead to the desired alteration of the GQDs optical properties, such as an increased photoluminescence intensity, a higher photoluminescence quantum yields (from 2.07 to 18.40%) and a narrowing of the spectral features in the emission spectra. The ability of gamma-irradiated GQDs to quench free radical species was investigated and positively assessed; additionally, non-enzymatic optical detection of Cu(II) ions using GQDs as a sensor was studied and the detection limits are
herein reported. These results suggest that GQDs can be potentially applied as smart photoluminescent sensors for metal cations.",
publisher = "Elsevier",
journal = "Ceramics International",
title = "Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing",
volume = "46",
number = "15",
pages = "23611-23622",
doi = "10.1016/j.ceramint.2020.06.133"
}

Jovanović, S., Dorontić, S., Jovanović, D., Ciasca, G., Budimir, M., Bonasera, A., Scopelliti, M., Marković, O.,& Todorović Marković, B.. (2020). Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing. in Ceramics International
Elsevier., 46(15), 23611-23622.
https://doi.org/10.1016/j.ceramint.2020.06.133

Jovanović S, Dorontić S, Jovanović D, Ciasca G, Budimir M, Bonasera A, Scopelliti M, Marković O, Todorović Marković B. Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing. in Ceramics International. 2020;46(15):23611-23622.
doi:10.1016/j.ceramint.2020.06.133 .

Jovanović, Svetlana, Dorontić, Slađana, Jovanović, Dragana, Ciasca, Gabriele, Budimir, Milica, Bonasera, Aurelio, Scopelliti, Michelangelo, Marković, Olivera, Todorović Marković, Biljana, "Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing" in Ceramics International, 46, no. 15 (2020):23611-23622,
https://doi.org/10.1016/j.ceramint.2020.06.133 . .

TY  - JOUR
AU  - Jovanović, Svetlana
AU  - Dorontić, Slađana
AU  - Jovanović, Dragana
AU  - Ciasca, Gabriele
AU  - Budimir, Milica
AU  - Bonasera, Aurelio
AU  - Scopelliti, Michelangelo
AU  - Marković, Olivera
AU  - Todorović Marković, Biljana
PY  - 2020
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3621
AB  - Due to the low consumption of chemicals, the absence of toxic residual side products, the procedure simplicity and time-saving aspects, gamma irradiation offers advantages over the classical chemical protocols. We successfully employed gamma irradiation in order to introduce N-atoms in Graphene Quantum Dots (GQDs). By irradiating GQDs water dispersions in the presence of isopropyl alcohol and ethylenediamine, at doses of 25, 50 and 200 kGy, we attached amino groups onto GQDs in a single synthetic step. At the same time, a chemical reduction is achieved, too. Selected conditions induced incorporation of N-atoms within GDQs atomic lattice (around 3 at%), at all applied doses. Additionally, the C-atoms percentage was highly increased, from 63 to 79 at % or higher. The zeta potential of dots changed from −34.6 to +9.1 mV, due to the modification of functionalizing groups localized at the surface. Produced chemical changes lead to the desired alteration of the GQDs optical properties, such as an increased photoluminescence intensity, a higher photoluminescence quantum yields (from 2.07 to 18.40%) and a narrowing of the spectral features in the emission spectra. The ability of gamma-irradiated GQDs to quench free radical species was investigated and positively assessed; additionally, non-enzymatic optical detection of Cu(II) ions using GQDs as a sensor was studied and the detection limits areherein reported. These results suggest that GQDs can be potentially applied as smart photoluminescent sensors for metal cations.
PB  - Elsevier
T2  - Ceramics International
T1  - Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing
VL  - 46
IS  - 15
SP  - 23611
EP  - 23622
DO  - 10.1016/j.ceramint.2020.06.133
ER  - 

@article{
author = "Jovanović, Svetlana and Dorontić, Slađana and Jovanović, Dragana and Ciasca, Gabriele and Budimir, Milica and Bonasera, Aurelio and Scopelliti, Michelangelo and Marković, Olivera and Todorović Marković, Biljana",
year = "2020",
abstract = "Due to the low consumption of chemicals, the absence of toxic residual side products, the procedure simplicity and time-saving aspects, gamma irradiation offers advantages over the classical chemical protocols. We successfully employed gamma irradiation in order to introduce N-atoms in Graphene Quantum Dots (GQDs). By irradiating GQDs water dispersions in the presence of isopropyl alcohol and ethylenediamine, at doses of 25, 50 and 200 kGy, we attached amino groups onto GQDs in a single synthetic step. At the same time, a chemical reduction is achieved, too. Selected conditions induced incorporation of N-atoms within GDQs atomic lattice (around 3 at%), at all applied doses. Additionally, the C-atoms percentage was highly increased, from 63 to 79 at % or higher. The zeta potential of dots changed from −34.6 to +9.1 mV, due to the modification of functionalizing groups localized at the surface. Produced chemical changes lead to the desired alteration of the GQDs optical properties, such as an increased photoluminescence intensity, a higher photoluminescence quantum yields (from 2.07 to 18.40%) and a narrowing of the spectral features in the emission spectra. The ability of gamma-irradiated GQDs to quench free radical species was investigated and positively assessed; additionally, non-enzymatic optical detection of Cu(II) ions using GQDs as a sensor was studied and the detection limits areherein reported. These results suggest that GQDs can be potentially applied as smart photoluminescent sensors for metal cations.",
publisher = "Elsevier",
journal = "Ceramics International",
title = "Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing",
volume = "46",
number = "15",
pages = "23611-23622",
doi = "10.1016/j.ceramint.2020.06.133"
}

Jovanović, S., Dorontić, S., Jovanović, D., Ciasca, G., Budimir, M., Bonasera, A., Scopelliti, M., Marković, O.,& Todorović Marković, B.. (2020). Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing. in Ceramics International
Elsevier., 46(15), 23611-23622.
https://doi.org/10.1016/j.ceramint.2020.06.133

Jovanović S, Dorontić S, Jovanović D, Ciasca G, Budimir M, Bonasera A, Scopelliti M, Marković O, Todorović Marković B. Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing. in Ceramics International. 2020;46(15):23611-23622.
doi:10.1016/j.ceramint.2020.06.133 .

Jovanović, Svetlana, Dorontić, Slađana, Jovanović, Dragana, Ciasca, Gabriele, Budimir, Milica, Bonasera, Aurelio, Scopelliti, Michelangelo, Marković, Olivera, Todorović Marković, Biljana, "Gamma irradiation of graphene quantum dots with ethylenediamine: Antioxidant for ion sensing" in Ceramics International, 46, no. 15 (2020):23611-23622,
https://doi.org/10.1016/j.ceramint.2020.06.133 . .

TY  - JOUR
AU  - Todorović-Marković, Biljana
AU  - Draganić, Ilija N.
AU  - Vasiljević-Radović, Dana
AU  - Romčević, Nebojša
AU  - Romčević, Maja
AU  - Dramićanin, Miroslav D.
AU  - Marković, Zoran
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/7483
AB  - In this paper, results of structural modification of fullerene thin films by single and multiple charged boron ions (B+, B3+) are presented. The applied ion energies were in the range of 15–45 keV. The characterization of as-deposited and irradiated specimens has been performed by atomic force microscopy, Raman and Fourier transform infrared spectroscopy and UV/vis spectrophotometry. The results of Raman analysis have shown the formation of amorphous layer after irradiation of fullerene thin films. Fourier transform infrared spectroscopy has confirmed the formation of new B–C bonds in irradiated films at higher fluences (2 × 1016 cm−2). The morphology of bombarded films has been changed significantly. The optical band gap was found to be reduced from 1.7 to 1.06 eV for irradiated films by B3+ ions and 0.7 eV for irradiated films by B+ ions.
PB  - Elsevier
T2  - Applied Surface Science
T1  - Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films
VL  - 253
IS  - 8
SP  - 4029
EP  - 4035
DO  - 10.1016/j.apsusc.2006.08.035
ER  - 

@article{
author = "Todorović-Marković, Biljana and Draganić, Ilija N. and Vasiljević-Radović, Dana and Romčević, Nebojša and Romčević, Maja and Dramićanin, Miroslav D. and Marković, Zoran",
year = "2007",
abstract = "In this paper, results of structural modification of fullerene thin films by single and multiple charged boron ions (B+, B3+) are presented. The applied ion energies were in the range of 15–45 keV. The characterization of as-deposited and irradiated specimens has been performed by atomic force microscopy, Raman and Fourier transform infrared spectroscopy and UV/vis spectrophotometry. The results of Raman analysis have shown the formation of amorphous layer after irradiation of fullerene thin films. Fourier transform infrared spectroscopy has confirmed the formation of new B–C bonds in irradiated films at higher fluences (2 × 1016 cm−2). The morphology of bombarded films has been changed significantly. The optical band gap was found to be reduced from 1.7 to 1.06 eV for irradiated films by B3+ ions and 0.7 eV for irradiated films by B+ ions.",
publisher = "Elsevier",
journal = "Applied Surface Science",
title = "Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films",
volume = "253",
number = "8",
pages = "4029-4035",
doi = "10.1016/j.apsusc.2006.08.035"
}

Todorović-Marković, B., Draganić, I. N., Vasiljević-Radović, D., Romčević, N., Romčević, M., Dramićanin, M. D.,& Marković, Z.. (2007). Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films. in Applied Surface Science
Elsevier., 253(8), 4029-4035.
https://doi.org/10.1016/j.apsusc.2006.08.035

Todorović-Marković B, Draganić IN, Vasiljević-Radović D, Romčević N, Romčević M, Dramićanin MD, Marković Z. Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films. in Applied Surface Science. 2007;253(8):4029-4035.
doi:10.1016/j.apsusc.2006.08.035 .

Todorović-Marković, Biljana, Draganić, Ilija N., Vasiljević-Radović, Dana, Romčević, Nebojša, Romčević, Maja, Dramićanin, Miroslav D., Marković, Zoran, "Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films" in Applied Surface Science, 253, no. 8 (2007):4029-4035,
https://doi.org/10.1016/j.apsusc.2006.08.035 . .

TY  - JOUR
AU  - Todorović-Marković, Biljana
AU  - Draganić, I.
AU  - Vasiljević-Radović, Dana
AU  - Romčević, N.
AU  - Blanuša, J.
AU  - Dramićanin, Miroslav
AU  - Marković, Zoran M.
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/338
AB  - In this paper, the results of structural modification of fullerene thin films bombarded by highly charged iron ions (Fe6+) have been presented. The properties of as-deposited and irradiated fullerene thin films have been investigated by Raman spectroscopy, UV/Vis spectrophotometry and atomic force microscopy (AFM). Results of Raman spectroscopy have indicated structural changes of irradiated thin films depending on fluences. It was found that iron doped fullerene films are dominated by sp3 rather than sp2 bonds after bombardment which might be due to formation of nano-diamond structures. AFM analysis showed that ion beam had destroyed the surface ordering. The optical band gap was found to be in the range of 0.6 to 1.4 eV for irradiated films by Fe6+ ions at the highest fluences.
AB  - U radu su prikazani rezultati strukturne modifikacije tankih slojeva fulerena koji su bombardovani višestruko naelektrisanim jonima gvožđa (Fe6+). Osobine deponovanih i bombardovanih tankih slojeva fulerena su ispitivane Ramanovom spektroskopijom, mikroskopom atomske sile (AFM), kao i UV/Vis spektrometrijom. Na osnovu rezultata dobijenih Ramanovom analizom može se zaključiti da dolazi do strukturnih promena u bombardovanim fulerenskim slojevima u zavisnosti od doze zračenja. Utvrđeno je da u tankim slojevima koji su bombardovani višestruko naelektrisanim jonima gvožđa dominiraju sp3 veze u odnosu na broj sp2 veza. Dominantno prisustvo sp3 veza u bombardovanim slojevima ukazuje na moguće formiranje dijamantu slične strukture. AFM analiza je pokazala da je promenjena morfologija bombardovanih uzoraka. Utvrđeno je da je energetski procep ozračenih slojeva u opsegu od 0.6 do 1.4 eV u zavisnosti od primenjene doze zračenja.
T2  - Tehnika - Novi materijali
T1  - Structural modification of fullerene thin films by highly charged iron ions
T1  - Strukturne modifikacije tankih slojeva fulerena pri bombardovanju višestruko naelektrisanim jonima gvožđa
VL  - 16
IS  - 3
SP  - 9
EP  - 14
UR  - https://hdl.handle.net/21.15107/rcub_cer_338
ER  - 

@article{
author = "Todorović-Marković, Biljana and Draganić, I. and Vasiljević-Radović, Dana and Romčević, N. and Blanuša, J. and Dramićanin, Miroslav and Marković, Zoran M.",
year = "2007",
abstract = "In this paper, the results of structural modification of fullerene thin films bombarded by highly charged iron ions (Fe6+) have been presented. The properties of as-deposited and irradiated fullerene thin films have been investigated by Raman spectroscopy, UV/Vis spectrophotometry and atomic force microscopy (AFM). Results of Raman spectroscopy have indicated structural changes of irradiated thin films depending on fluences. It was found that iron doped fullerene films are dominated by sp3 rather than sp2 bonds after bombardment which might be due to formation of nano-diamond structures. AFM analysis showed that ion beam had destroyed the surface ordering. The optical band gap was found to be in the range of 0.6 to 1.4 eV for irradiated films by Fe6+ ions at the highest fluences., U radu su prikazani rezultati strukturne modifikacije tankih slojeva fulerena koji su bombardovani višestruko naelektrisanim jonima gvožđa (Fe6+). Osobine deponovanih i bombardovanih tankih slojeva fulerena su ispitivane Ramanovom spektroskopijom, mikroskopom atomske sile (AFM), kao i UV/Vis spektrometrijom. Na osnovu rezultata dobijenih Ramanovom analizom može se zaključiti da dolazi do strukturnih promena u bombardovanim fulerenskim slojevima u zavisnosti od doze zračenja. Utvrđeno je da u tankim slojevima koji su bombardovani višestruko naelektrisanim jonima gvožđa dominiraju sp3 veze u odnosu na broj sp2 veza. Dominantno prisustvo sp3 veza u bombardovanim slojevima ukazuje na moguće formiranje dijamantu slične strukture. AFM analiza je pokazala da je promenjena morfologija bombardovanih uzoraka. Utvrđeno je da je energetski procep ozračenih slojeva u opsegu od 0.6 do 1.4 eV u zavisnosti od primenjene doze zračenja.",
journal = "Tehnika - Novi materijali",
title = "Structural modification of fullerene thin films by highly charged iron ions, Strukturne modifikacije tankih slojeva fulerena pri bombardovanju višestruko naelektrisanim jonima gvožđa",
volume = "16",
number = "3",
pages = "9-14",
url = "https://hdl.handle.net/21.15107/rcub_cer_338"
}

Todorović-Marković, B., Draganić, I., Vasiljević-Radović, D., Romčević, N., Blanuša, J., Dramićanin, M.,& Marković, Z. M.. (2007). Structural modification of fullerene thin films by highly charged iron ions. in Tehnika - Novi materijali, 16(3), 9-14.
https://hdl.handle.net/21.15107/rcub_cer_338

Todorović-Marković B, Draganić I, Vasiljević-Radović D, Romčević N, Blanuša J, Dramićanin M, Marković ZM. Structural modification of fullerene thin films by highly charged iron ions. in Tehnika - Novi materijali. 2007;16(3):9-14.
https://hdl.handle.net/21.15107/rcub_cer_338 .

Todorović-Marković, Biljana, Draganić, I., Vasiljević-Radović, Dana, Romčević, N., Blanuša, J., Dramićanin, Miroslav, Marković, Zoran M., "Structural modification of fullerene thin films by highly charged iron ions" in Tehnika - Novi materijali, 16, no. 3 (2007):9-14,
https://hdl.handle.net/21.15107/rcub_cer_338 .

TY  - JOUR
AU  - Todorović-Marković, Biljana
AU  - Draganić, I.
AU  - Vasiljević-Radović, Dana
AU  - Romčević, N.
AU  - Blanuša, J.
AU  - Dramićanin, Miroslav
AU  - Marković, Zoran M.
PY  - 2007
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3188
AB  - In this paper, the results of structural modification of fullerene thin films bombarded by highly charged iron ions (Fe6+) are presented. The properties of as-deposited and irradiated fullerene thin films have been investigated by Raman spectroscopy, UV/Vis spectrophotometry and atomic force microscopy (AFM). The results of Raman spectroscopy have indicated structural changes of irradiated thin films depending on fluences. It was found that iron doped fullerene films are dominated by sp3 rather than sp2 after bombardment which might be due to formation of nanodiamond structures. AFM analysis showed that the ion beam had destroyed the surface ordering. The optical band gap was found to be in the range of 0.6 to 1.4 eV for irradiated films by Fe6+ ions at the highest fluences.
PB  - Springer
T2  - Applied Physics A: Materials Science and Processing
T1  - Structural modification of fullerene thin films by highly charged iron ions
VL  - 89
SP  - 749
EP  - 754
DO  - 10.1007/s00339-007-4162-y
ER  - 

@article{
author = "Todorović-Marković, Biljana and Draganić, I. and Vasiljević-Radović, Dana and Romčević, N. and Blanuša, J. and Dramićanin, Miroslav and Marković, Zoran M.",
year = "2007",
abstract = "In this paper, the results of structural modification of fullerene thin films bombarded by highly charged iron ions (Fe6+) are presented. The properties of as-deposited and irradiated fullerene thin films have been investigated by Raman spectroscopy, UV/Vis spectrophotometry and atomic force microscopy (AFM). The results of Raman spectroscopy have indicated structural changes of irradiated thin films depending on fluences. It was found that iron doped fullerene films are dominated by sp3 rather than sp2 after bombardment which might be due to formation of nanodiamond structures. AFM analysis showed that the ion beam had destroyed the surface ordering. The optical band gap was found to be in the range of 0.6 to 1.4 eV for irradiated films by Fe6+ ions at the highest fluences.",
publisher = "Springer",
journal = "Applied Physics A: Materials Science and Processing",
title = "Structural modification of fullerene thin films by highly charged iron ions",
volume = "89",
pages = "749-754",
doi = "10.1007/s00339-007-4162-y"
}

Todorović-Marković, B., Draganić, I., Vasiljević-Radović, D., Romčević, N., Blanuša, J., Dramićanin, M.,& Marković, Z. M.. (2007). Structural modification of fullerene thin films by highly charged iron ions. in Applied Physics A: Materials Science and Processing
Springer., 89, 749-754.
https://doi.org/10.1007/s00339-007-4162-y

Todorović-Marković B, Draganić I, Vasiljević-Radović D, Romčević N, Blanuša J, Dramićanin M, Marković ZM. Structural modification of fullerene thin films by highly charged iron ions. in Applied Physics A: Materials Science and Processing. 2007;89:749-754.
doi:10.1007/s00339-007-4162-y .

Todorović-Marković, Biljana, Draganić, I., Vasiljević-Radović, Dana, Romčević, N., Blanuša, J., Dramićanin, Miroslav, Marković, Zoran M., "Structural modification of fullerene thin films by highly charged iron ions" in Applied Physics A: Materials Science and Processing, 89 (2007):749-754,
https://doi.org/10.1007/s00339-007-4162-y . .

TY  - JOUR
AU  - Todorović-Marković, Biljana
AU  - Draganić, Ilija
AU  - Vasiljević-Radović, Dana
AU  - Romčević, Nebojša
AU  - Romčević, Maja
AU  - Dramićanin, Miroslav
AU  - Marković, Zoran M.
PY  - 2006
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/272
AB  - In this paper, results of structural modification of fullerene thin films by single and multiple charged boron ions (B+, B3+) are presented. The applied ion energies were in the range of 15 to 45 keV. The characterization of as-deposited and irradiated specimens has been performed by atomic force microscopy, Raman and Fourier transform infrared spectroscopy and UV/VIS spectrophotometry. The results of Raman analysis have shown the formation of amorphous layer after irradiation of fullerene thin films. Fourier transform infrared spectroscopy has confirmed the formation of new B-C bonds in irradiated films at higher fluences (2x1016 cm-2). The morphology of bombarded films has been changed significantly. The optical band gap was found to be reduced from 1.7 to 1.06 eV for irradiated films by B3+ ions and 0.7 eV for irradiated films by B+ ions.
AB  - U radu su prikazani rezultati strukturne modifikacije tankih slojeva fulerena bombardovanjem jednostruko i višestruko naelektrisanim jonima bora (B+, B3+). Energije korišćenih jona su bile u opsegu od 15 do 45 keV. Osobine deponovanih i ozračenih fulerenskih slojeva su proučavane pomoću mikroskopa atomske snage (AFM), Ramanovom i Furijeovom infracrvenom spektroskopijom (FTIR) i UV/VIS spektrometrijom. Rezultati koji su dobijeni na osnovu Ramanove spektroskopije su pokazali da se posle ozračivanja formirao sloj amorfnog ugljenika na površini uzorka. Furijeova infracrvena spektroskopija je pokazala da su se unutar ozračenog sloja formirale veze bora i ugljenika. Morfologija fulerenskih slojeva se značajno promenila posle bombardovanja jonima bora. Utvrđeno je da se energetski procep ozračenih slojeva smanjio sa 1.7 eV na 1.06 eV za slojeve bombardovane trostruko naelektrisanim jonima bora, i na 0.7 eV za slojeve bombardovane B+ jonima.
T2  - Tehnika - Novi materijali
T1  - Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films
T1  - Sinteza amorfnog bor karbida bombardovanjem tankih slojeva fulerena jonima bora
VL  - 15
IS  - 6
SP  - 7
EP  - 13
UR  - https://hdl.handle.net/21.15107/rcub_cer_272
ER  - 

@article{
author = "Todorović-Marković, Biljana and Draganić, Ilija and Vasiljević-Radović, Dana and Romčević, Nebojša and Romčević, Maja and Dramićanin, Miroslav and Marković, Zoran M.",
year = "2006",
abstract = "In this paper, results of structural modification of fullerene thin films by single and multiple charged boron ions (B+, B3+) are presented. The applied ion energies were in the range of 15 to 45 keV. The characterization of as-deposited and irradiated specimens has been performed by atomic force microscopy, Raman and Fourier transform infrared spectroscopy and UV/VIS spectrophotometry. The results of Raman analysis have shown the formation of amorphous layer after irradiation of fullerene thin films. Fourier transform infrared spectroscopy has confirmed the formation of new B-C bonds in irradiated films at higher fluences (2x1016 cm-2). The morphology of bombarded films has been changed significantly. The optical band gap was found to be reduced from 1.7 to 1.06 eV for irradiated films by B3+ ions and 0.7 eV for irradiated films by B+ ions., U radu su prikazani rezultati strukturne modifikacije tankih slojeva fulerena bombardovanjem jednostruko i višestruko naelektrisanim jonima bora (B+, B3+). Energije korišćenih jona su bile u opsegu od 15 do 45 keV. Osobine deponovanih i ozračenih fulerenskih slojeva su proučavane pomoću mikroskopa atomske snage (AFM), Ramanovom i Furijeovom infracrvenom spektroskopijom (FTIR) i UV/VIS spektrometrijom. Rezultati koji su dobijeni na osnovu Ramanove spektroskopije su pokazali da se posle ozračivanja formirao sloj amorfnog ugljenika na površini uzorka. Furijeova infracrvena spektroskopija je pokazala da su se unutar ozračenog sloja formirale veze bora i ugljenika. Morfologija fulerenskih slojeva se značajno promenila posle bombardovanja jonima bora. Utvrđeno je da se energetski procep ozračenih slojeva smanjio sa 1.7 eV na 1.06 eV za slojeve bombardovane trostruko naelektrisanim jonima bora, i na 0.7 eV za slojeve bombardovane B+ jonima.",
journal = "Tehnika - Novi materijali",
title = "Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films, Sinteza amorfnog bor karbida bombardovanjem tankih slojeva fulerena jonima bora",
volume = "15",
number = "6",
pages = "7-13",
url = "https://hdl.handle.net/21.15107/rcub_cer_272"
}

Todorović-Marković, B., Draganić, I., Vasiljević-Radović, D., Romčević, N., Romčević, M., Dramićanin, M.,& Marković, Z. M.. (2006). Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films. in Tehnika - Novi materijali, 15(6), 7-13.
https://hdl.handle.net/21.15107/rcub_cer_272

Todorović-Marković B, Draganić I, Vasiljević-Radović D, Romčević N, Romčević M, Dramićanin M, Marković ZM. Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films. in Tehnika - Novi materijali. 2006;15(6):7-13.
https://hdl.handle.net/21.15107/rcub_cer_272 .

Todorović-Marković, Biljana, Draganić, Ilija, Vasiljević-Radović, Dana, Romčević, Nebojša, Romčević, Maja, Dramićanin, Miroslav, Marković, Zoran M., "Synthesis of amorphous boron carbide by single and multiple charged boron ions bombardment of fullerene thin films" in Tehnika - Novi materijali, 15, no. 6 (2006):7-13,
https://hdl.handle.net/21.15107/rcub_cer_272 .

TY  - JOUR
AU  - Isaković, Aleksandra
AU  - Marković, Zoran M.
AU  - Nikolić, Nadežda
AU  - Todorović-Marković, Biljana
AU  - Vranješ-Đurić, Sanja
AU  - Harhaji, Ljubica
AU  - Raičević, Nevena
AU  - Romčević, Nebojša
AU  - Vasiljević-Radović, Dana
AU  - Dramićanin, Miroslav
AU  - Trajković, Vladimir
PY  - 2006
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4120
AB  - We investigated the effect of γ-irradiation on the cytotoxicity of pure C 60 solubilized in water by using tetrahydrofuran (THF/n-C 60 or THF/n-C 60 ). In contrast to THF/n-C 60 , its γ-irradiated counterpart failed to generate oxygen radicals and cause extracellular signal-regulated kinase (ERK)-dependent necrotic cell death in various types of mammalian cells. Moreover, γ-irradiated THF/n-C 60 protected cells from the oxidative stress induced by native THF/n-C 60 or hydrogen peroxide. The observed biological effects were associated with γ-irradiation-mediated decomposition of THF and subsequent derivatization of the n-C 60 surface. These results for the first time demonstrate γ-irradiation-mediated changes in the physico-chemical properties of THF-prepared nanocrystalline C 60 , resulting in a complete loss of its cytotoxic effect and its conversion to a cytoprotective agent.
PB  - Elsevier
T2  - Biomaterials
T1  - Inactivation of nanocrystalline C60 cytotoxicity by γ-irradiation
VL  - 27
IS  - 29
SP  - 5049
EP  - 5058
DO  - 10.1016/j.biomaterials.2006.05.047
ER  - 

@article{
author = "Isaković, Aleksandra and Marković, Zoran M. and Nikolić, Nadežda and Todorović-Marković, Biljana and Vranješ-Đurić, Sanja and Harhaji, Ljubica and Raičević, Nevena and Romčević, Nebojša and Vasiljević-Radović, Dana and Dramićanin, Miroslav and Trajković, Vladimir",
year = "2006",
abstract = "We investigated the effect of γ-irradiation on the cytotoxicity of pure C 60 solubilized in water by using tetrahydrofuran (THF/n-C 60 or THF/n-C 60 ). In contrast to THF/n-C 60 , its γ-irradiated counterpart failed to generate oxygen radicals and cause extracellular signal-regulated kinase (ERK)-dependent necrotic cell death in various types of mammalian cells. Moreover, γ-irradiated THF/n-C 60 protected cells from the oxidative stress induced by native THF/n-C 60 or hydrogen peroxide. The observed biological effects were associated with γ-irradiation-mediated decomposition of THF and subsequent derivatization of the n-C 60 surface. These results for the first time demonstrate γ-irradiation-mediated changes in the physico-chemical properties of THF-prepared nanocrystalline C 60 , resulting in a complete loss of its cytotoxic effect and its conversion to a cytoprotective agent.",
publisher = "Elsevier",
journal = "Biomaterials",
title = "Inactivation of nanocrystalline C60 cytotoxicity by γ-irradiation",
volume = "27",
number = "29",
pages = "5049-5058",
doi = "10.1016/j.biomaterials.2006.05.047"
}

Isaković, A., Marković, Z. M., Nikolić, N., Todorović-Marković, B., Vranješ-Đurić, S., Harhaji, L., Raičević, N., Romčević, N., Vasiljević-Radović, D., Dramićanin, M.,& Trajković, V.. (2006). Inactivation of nanocrystalline C60 cytotoxicity by γ-irradiation. in Biomaterials
Elsevier., 27(29), 5049-5058.
https://doi.org/10.1016/j.biomaterials.2006.05.047

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