TY  - JOUR
AU  - Asakawa, Yoshinori
AU  - Ludwiczuk, Agnieszka
AU  - Novaković, Miroslav
AU  - Bukvicki, Danka
AU  - Anchang, Kenneth Yongabi
PY  - 2022
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/5404
AB  - The Marchantiophyta (liverworts) are rich sources of phenolic substances, especially cyclic and acyclic bis-bibenzyls, which are rare natural products in the plant kingdom, together with bibenzyls and characteristic terpenoids. At present, more than 125 bis-bibenzyls have been found in liverworts. They are biosynthesized from the dimerization of lunularic acid via dihydrocoumaric acid and prelunularin. The structurally unusual cyclic and acyclic bis-bibenzyls show various biological activities such as antimicrobial, antifungal, cytotoxic, muscle relaxation, antioxidant, tubulin polymerization inhibitory, and antitrypanosomal activities, among others. The present review article deals with the distribution and structure of bis-bibenzyls, bibenzyls, and several characteristic ent-sesqui- and diterpenoids in liverworts. Furthermore, the biosynthesis and total syntheses and biological activities of bis-bibenzyls are also surveyed.
PB  - USA : American Chemical Society
T2  - Journal of Natural Products
T1  - Bis-bibenzyls, Bibenzyls, and Terpenoids in 33 Genera of the Marchantiophyta (Liverworts): Structures, Synthesis, and Bioactivity
VL  - 85
IS  - 3
SP  - 729
EP  - 762
DO  - 10.1021/acs.jnatprod.1c00302
ER  - 

@article{
author = "Asakawa, Yoshinori and Ludwiczuk, Agnieszka and Novaković, Miroslav and Bukvicki, Danka and Anchang, Kenneth Yongabi",
year = "2022",
abstract = "The Marchantiophyta (liverworts) are rich sources of phenolic substances, especially cyclic and acyclic bis-bibenzyls, which are rare natural products in the plant kingdom, together with bibenzyls and characteristic terpenoids. At present, more than 125 bis-bibenzyls have been found in liverworts. They are biosynthesized from the dimerization of lunularic acid via dihydrocoumaric acid and prelunularin. The structurally unusual cyclic and acyclic bis-bibenzyls show various biological activities such as antimicrobial, antifungal, cytotoxic, muscle relaxation, antioxidant, tubulin polymerization inhibitory, and antitrypanosomal activities, among others. The present review article deals with the distribution and structure of bis-bibenzyls, bibenzyls, and several characteristic ent-sesqui- and diterpenoids in liverworts. Furthermore, the biosynthesis and total syntheses and biological activities of bis-bibenzyls are also surveyed.",
publisher = "USA : American Chemical Society",
journal = "Journal of Natural Products",
title = "Bis-bibenzyls, Bibenzyls, and Terpenoids in 33 Genera of the Marchantiophyta (Liverworts): Structures, Synthesis, and Bioactivity",
volume = "85",
number = "3",
pages = "729-762",
doi = "10.1021/acs.jnatprod.1c00302"
}

Asakawa, Y., Ludwiczuk, A., Novaković, M., Bukvicki, D.,& Anchang, K. Y.. (2022). Bis-bibenzyls, Bibenzyls, and Terpenoids in 33 Genera of the Marchantiophyta (Liverworts): Structures, Synthesis, and Bioactivity. in Journal of Natural Products
USA : American Chemical Society., 85(3), 729-762.
https://doi.org/10.1021/acs.jnatprod.1c00302

Asakawa Y, Ludwiczuk A, Novaković M, Bukvicki D, Anchang KY. Bis-bibenzyls, Bibenzyls, and Terpenoids in 33 Genera of the Marchantiophyta (Liverworts): Structures, Synthesis, and Bioactivity. in Journal of Natural Products. 2022;85(3):729-762.
doi:10.1021/acs.jnatprod.1c00302 .

Asakawa, Yoshinori, Ludwiczuk, Agnieszka, Novaković, Miroslav, Bukvicki, Danka, Anchang, Kenneth Yongabi, "Bis-bibenzyls, Bibenzyls, and Terpenoids in 33 Genera of the Marchantiophyta (Liverworts): Structures, Synthesis, and Bioactivity" in Journal of Natural Products, 85, no. 3 (2022):729-762,
https://doi.org/10.1021/acs.jnatprod.1c00302 . .

TY  - JOUR
AU  - Novakovic, Miroslav
AU  - Ludwiczuk, Agnieszka
AU  - Bukvicki, Danka
AU  - Asakawa, Yoshinori
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4906
AB  - Little attention has been paid to the bryophytes as sources for human diet despite the presence of 23,000 species in the world. Some mosses contain Vitamin B1, tocopherols, prostaglandin-like highly unsaturated fatty acids and phenolic compounds. On the other hand, liverworts contain enantiomeric mono-, sesqui- and diterpenoids similar to those found in vascular plants. Additionally, they possess bibenzyls, bis-bibenzyls and polyketides, many of them showing various bioactivity, such as antimicrobial, antiviral, anti-inf­lam­matory, cytotoxicity against cancer cell lines, muscle relaxing, antioxidant and others. In this paper, the structures of phytochemicals from bryophytes and their biological activities are discussed.
AB  - На бриофите као изворе за људску исхрану се обраћа мала пажња иако их има преко 23000 врста. Неке маховине садрже витамин Б1, токофероле, простагландинима слична једињења, вишеструко незасићене масне киселине и фенолна једињења. С друге стране, јетрењаче садрже моно-, сескви- и дитерпеноиде енентиомерне онима пронађеним у васкуларним биљкама. Поред њих, оне садрже и бибензиле, бис-бибензиле и
поликетиде, од којих многи показују антимикробну, антивирусну, анти-инфламаторну, цитотоксичну на ћелије рака, миорекласантску, антиоксидативну и друге. У овом раду су продискутоване структуре и биолошка активност фитохемикалија из јетрењача.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Phytochemicals from bryophytes: Structures and biological activity
T1  - Фитохемикалије из бриофита: структура и биолошке активности
VL  - 86
IS  - 12
SP  - 1139
EP  - 1175
DO  - 10.2298/JSC211027100N
ER  - 

@article{
author = "Novakovic, Miroslav and Ludwiczuk, Agnieszka and Bukvicki, Danka and Asakawa, Yoshinori",
year = "2021",
abstract = "Little attention has been paid to the bryophytes as sources for human diet despite the presence of 23,000 species in the world. Some mosses contain Vitamin B1, tocopherols, prostaglandin-like highly unsaturated fatty acids and phenolic compounds. On the other hand, liverworts contain enantiomeric mono-, sesqui- and diterpenoids similar to those found in vascular plants. Additionally, they possess bibenzyls, bis-bibenzyls and polyketides, many of them showing various bioactivity, such as antimicrobial, antiviral, anti-inf­lam­matory, cytotoxicity against cancer cell lines, muscle relaxing, antioxidant and others. In this paper, the structures of phytochemicals from bryophytes and their biological activities are discussed., На бриофите као изворе за људску исхрану се обраћа мала пажња иако их има преко 23000 врста. Неке маховине садрже витамин Б1, токофероле, простагландинима слична једињења, вишеструко незасићене масне киселине и фенолна једињења. С друге стране, јетрењаче садрже моно-, сескви- и дитерпеноиде енентиомерне онима пронађеним у васкуларним биљкама. Поред њих, оне садрже и бибензиле, бис-бибензиле и
поликетиде, од којих многи показују антимикробну, антивирусну, анти-инфламаторну, цитотоксичну на ћелије рака, миорекласантску, антиоксидативну и друге. У овом раду су продискутоване структуре и биолошка активност фитохемикалија из јетрењача.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Phytochemicals from bryophytes: Structures and biological activity, Фитохемикалије из бриофита: структура и биолошке активности",
volume = "86",
number = "12",
pages = "1139-1175",
doi = "10.2298/JSC211027100N"
}

Novakovic, M., Ludwiczuk, A., Bukvicki, D.,& Asakawa, Y.. (2021). Phytochemicals from bryophytes: Structures and biological activity. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 86(12), 1139-1175.
https://doi.org/10.2298/JSC211027100N

Novakovic M, Ludwiczuk A, Bukvicki D, Asakawa Y. Phytochemicals from bryophytes: Structures and biological activity. in Journal of the Serbian Chemical Society. 2021;86(12):1139-1175.
doi:10.2298/JSC211027100N .

Novakovic, Miroslav, Ludwiczuk, Agnieszka, Bukvicki, Danka, Asakawa, Yoshinori, "Phytochemicals from bryophytes: Structures and biological activity" in Journal of the Serbian Chemical Society, 86, no. 12 (2021):1139-1175,
https://doi.org/10.2298/JSC211027100N . .