Foršek, J.

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New approach to the aromatization of ring B in 19-norsteroids and to the synthesis of equilenin-type compounds

Mihailović, Milhailo Lj.; Foršek, J.; Lorenc, Ljubinka

(Royal Society of Chemistry, 1978)

TY  - JOUR
AU  - Mihailović, Milhailo Lj.
AU  - Foršek, J.
AU  - Lorenc, Ljubinka
PY  - 1978
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2761
AB  - When 7α-acetoxy-3,3 : 17,17-bis(ethylenedioxy)-5,10-epoxy-5β, 10β-oestran-6-one (2), formed by lead tetra-acetate acetoxylation of the parent compound (1), is heated with alkali, it undergoes ring B aromatization to give 3,3: 17,17-bis(ethylenedioxy)-5(10),6,8-oestratriene-6,7-diol (3), without configurational change at C(14); deacetalization of the corresponding diacetate (4), followed by lead tetra-acetate aromatization of ring A in the resulting diketone (5), produces 6,7-diacetoxy-equilenin (6), which is finally converted into its 3-acetate (7).
PB  - Royal Society of Chemistry
T2  - Journal of the Chemical Society, Chemical Communications
T1  - New approach to the aromatization of ring B in 19-norsteroids and to the synthesis of equilenin-type compounds
IS  - 21
SP  - 916
EP  - 918
DO  - 10.1039/C39780000916
ER  - 
@article{
author = "Mihailović, Milhailo Lj. and Foršek, J. and Lorenc, Ljubinka",
year = "1978",
abstract = "When 7α-acetoxy-3,3 : 17,17-bis(ethylenedioxy)-5,10-epoxy-5β, 10β-oestran-6-one (2), formed by lead tetra-acetate acetoxylation of the parent compound (1), is heated with alkali, it undergoes ring B aromatization to give 3,3: 17,17-bis(ethylenedioxy)-5(10),6,8-oestratriene-6,7-diol (3), without configurational change at C(14); deacetalization of the corresponding diacetate (4), followed by lead tetra-acetate aromatization of ring A in the resulting diketone (5), produces 6,7-diacetoxy-equilenin (6), which is finally converted into its 3-acetate (7).",
publisher = "Royal Society of Chemistry",
journal = "Journal of the Chemical Society, Chemical Communications",
title = "New approach to the aromatization of ring B in 19-norsteroids and to the synthesis of equilenin-type compounds",
number = "21",
pages = "916-918",
doi = "10.1039/C39780000916"
}
Mihailović, M. Lj., Foršek, J.,& Lorenc, L.. (1978). New approach to the aromatization of ring B in 19-norsteroids and to the synthesis of equilenin-type compounds. in Journal of the Chemical Society, Chemical Communications
Royal Society of Chemistry.(21), 916-918.
https://doi.org/10.1039/C39780000916
Mihailović ML, Foršek J, Lorenc L. New approach to the aromatization of ring B in 19-norsteroids and to the synthesis of equilenin-type compounds. in Journal of the Chemical Society, Chemical Communications. 1978;(21):916-918.
doi:10.1039/C39780000916 .
Mihailović, Milhailo Lj., Foršek, J., Lorenc, Ljubinka, "New approach to the aromatization of ring B in 19-norsteroids and to the synthesis of equilenin-type compounds" in Journal of the Chemical Society, Chemical Communications, no. 21 (1978):916-918,
https://doi.org/10.1039/C39780000916 . .
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