TY  - JOUR
AU  - Ilić, Slavica B.
AU  - Konstantinović, Sandra S.
AU  - Ćirić, Jovan
AU  - Savić, Dragiša
AU  - Gojgić-Cvijović, Gordana
AU  - Veljković, Vlada B.
PY  - 2016
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/1994
AB  - The microorganisam Streptomyces hygroscopicus CH-7 produces antibiotics Hexaene, Nigericine and Elaiophyline. The yield of antibiotics can be increased by changing the fermentation conditions and the composition of the nutrient medium. Based on the previous research with this strain and the literature reviewed, the aim of this work was to study the possibility of using waste materials (whey with proteins in varying ammounts and crude glycerol from the biodiesel production) as a carbon and nitrogen source in order to increase the yeald of antibiotics produced by Streptomyces hygroscopicus CH-7. The maximum concentration of Hexaene (47,2 μg/ cm3) was achieved in the medium with whey containing 80% of protein and glycerol from sunflower oil, while the maximum concentration of Elaiophyline (24,3μg/cm3) was achived in the basal medium.
AB  - Mikroorganizam Streptomyces hygroscopicus CH-7 produkuje antibiotike Heksaen, Nigericin i Elaiofilin. Promenom uslova fermentacije i sastava hranljive podloge može se povećati produkcija antibiotika. Na osnovu dosadašnjih istraživanja sa ovim sojem i literaturnog pregleda, cilj ovog rada je bio da se ispita mogućnost primene otpadnih sirovina (surutke sa različitim procentom proteina i sirovog glicerola iz proizvodnje biodizela) kao izvora ugljenika i azota, kako bi se povećala produkcija antibiotika pomoću Streptomyces hygroscopicus CH-7. Maksimalna koncentracija Heksaena (47,2 μg/cm 3) postignuta je na podlozi sa surutkom (koja sadrži 80% proteina) i glicerolom iz suncokretovog ulja, dok je maksimalna koncentracija Elaiofilina (24,3μg/cm3) ostvarena na osnovnoj podlozi.
PB  - Tehnološki fakultet, Leskovac
T2  - Advanced Technologies
T1  - Crude glycerol and whey as carbon and nitrogen sources for the production of antibiotics
T1  - Sirovi glicerol i surutka kao izvori ugljenika i azota za produkciju antibiotika
VL  - 5
IS  - 1
SP  - 5
EP  - 9
DO  - 10.5937/savteh1601005I
ER  - 

@article{
author = "Ilić, Slavica B. and Konstantinović, Sandra S. and Ćirić, Jovan and Savić, Dragiša and Gojgić-Cvijović, Gordana and Veljković, Vlada B.",
year = "2016",
abstract = "The microorganisam Streptomyces hygroscopicus CH-7 produces antibiotics Hexaene, Nigericine and Elaiophyline. The yield of antibiotics can be increased by changing the fermentation conditions and the composition of the nutrient medium. Based on the previous research with this strain and the literature reviewed, the aim of this work was to study the possibility of using waste materials (whey with proteins in varying ammounts and crude glycerol from the biodiesel production) as a carbon and nitrogen source in order to increase the yeald of antibiotics produced by Streptomyces hygroscopicus CH-7. The maximum concentration of Hexaene (47,2 μg/ cm3) was achieved in the medium with whey containing 80% of protein and glycerol from sunflower oil, while the maximum concentration of Elaiophyline (24,3μg/cm3) was achived in the basal medium., Mikroorganizam Streptomyces hygroscopicus CH-7 produkuje antibiotike Heksaen, Nigericin i Elaiofilin. Promenom uslova fermentacije i sastava hranljive podloge može se povećati produkcija antibiotika. Na osnovu dosadašnjih istraživanja sa ovim sojem i literaturnog pregleda, cilj ovog rada je bio da se ispita mogućnost primene otpadnih sirovina (surutke sa različitim procentom proteina i sirovog glicerola iz proizvodnje biodizela) kao izvora ugljenika i azota, kako bi se povećala produkcija antibiotika pomoću Streptomyces hygroscopicus CH-7. Maksimalna koncentracija Heksaena (47,2 μg/cm 3) postignuta je na podlozi sa surutkom (koja sadrži 80% proteina) i glicerolom iz suncokretovog ulja, dok je maksimalna koncentracija Elaiofilina (24,3μg/cm3) ostvarena na osnovnoj podlozi.",
publisher = "Tehnološki fakultet, Leskovac",
journal = "Advanced Technologies",
title = "Crude glycerol and whey as carbon and nitrogen sources for the production of antibiotics, Sirovi glicerol i surutka kao izvori ugljenika i azota za produkciju antibiotika",
volume = "5",
number = "1",
pages = "5-9",
doi = "10.5937/savteh1601005I"
}

Ilić, S. B., Konstantinović, S. S., Ćirić, J., Savić, D., Gojgić-Cvijović, G.,& Veljković, V. B.. (2016). Crude glycerol and whey as carbon and nitrogen sources for the production of antibiotics. in Advanced Technologies
Tehnološki fakultet, Leskovac., 5(1), 5-9.
https://doi.org/10.5937/savteh1601005I

Ilić SB, Konstantinović SS, Ćirić J, Savić D, Gojgić-Cvijović G, Veljković VB. Crude glycerol and whey as carbon and nitrogen sources for the production of antibiotics. in Advanced Technologies. 2016;5(1):5-9.
doi:10.5937/savteh1601005I .

Ilić, Slavica B., Konstantinović, Sandra S., Ćirić, Jovan, Savić, Dragiša, Gojgić-Cvijović, Gordana, Veljković, Vlada B., "Crude glycerol and whey as carbon and nitrogen sources for the production of antibiotics" in Advanced Technologies, 5, no. 1 (2016):5-9,
https://doi.org/10.5937/savteh1601005I . .