TY  - JOUR
AU  - Milovanović, Stoja
AU  - Đuriš, Jelena
AU  - Dapčević, Aleksandra
AU  - Lučić-Škorić, Marija
AU  - Medarević, Đorđe
AU  - Pavlović, Stefan
AU  - Ibrić, Svetlana
PY  - 2021
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4198
AB  - This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa and temperature of 100 °C during 2 h) enabled preparation of stable porous valsartan formulations which was confirmed with FESEM and mercury intrusion porosimetry analysis. The bulk density of obtained formulations was lower than 550 kg/m3. FTIR, DSC, and PXRD analysis indicated that there was no chemical interaction between the drug and polymers and that amorphous solid dispersions were obtained. Formulations with Soluplus® and HPMCAS retained its buoyancy in 0.1 M HCl for longer than 24 h, while formulation with Eudragit® E100 retained its buoyancy up to 2 h. Controlled valsartan release was influenced by solubility of polymers in the tested release medium, which was confirmed by UV/VIS spectroscopy. The obtained results provided framework for further development of floating drug delivery system using an environmental friendly process.
PB  - Springer
T2  - Journal of Polymer Research
T1  - Preparation of floating polymer-valsartan delivery systems using supercritical CO2
VL  - 28
SP  - 74
DO  - 10.1007/s10965-021-02440-1
ER  - 

@article{
author = "Milovanović, Stoja and Đuriš, Jelena and Dapčević, Aleksandra and Lučić-Škorić, Marija and Medarević, Đorđe and Pavlović, Stefan and Ibrić, Svetlana",
year = "2021",
abstract = "This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa and temperature of 100 °C during 2 h) enabled preparation of stable porous valsartan formulations which was confirmed with FESEM and mercury intrusion porosimetry analysis. The bulk density of obtained formulations was lower than 550 kg/m3. FTIR, DSC, and PXRD analysis indicated that there was no chemical interaction between the drug and polymers and that amorphous solid dispersions were obtained. Formulations with Soluplus® and HPMCAS retained its buoyancy in 0.1 M HCl for longer than 24 h, while formulation with Eudragit® E100 retained its buoyancy up to 2 h. Controlled valsartan release was influenced by solubility of polymers in the tested release medium, which was confirmed by UV/VIS spectroscopy. The obtained results provided framework for further development of floating drug delivery system using an environmental friendly process.",
publisher = "Springer",
journal = "Journal of Polymer Research",
title = "Preparation of floating polymer-valsartan delivery systems using supercritical CO2",
volume = "28",
pages = "74",
doi = "10.1007/s10965-021-02440-1"
}

Milovanović, S., Đuriš, J., Dapčević, A., Lučić-Škorić, M., Medarević, Đ., Pavlović, S.,& Ibrić, S.. (2021). Preparation of floating polymer-valsartan delivery systems using supercritical CO2. in Journal of Polymer Research
Springer., 28, 74.
https://doi.org/10.1007/s10965-021-02440-1

Milovanović S, Đuriš J, Dapčević A, Lučić-Škorić M, Medarević Đ, Pavlović S, Ibrić S. Preparation of floating polymer-valsartan delivery systems using supercritical CO2. in Journal of Polymer Research. 2021;28:74.
doi:10.1007/s10965-021-02440-1 .

Milovanović, Stoja, Đuriš, Jelena, Dapčević, Aleksandra, Lučić-Škorić, Marija, Medarević, Đorđe, Pavlović, Stefan, Ibrić, Svetlana, "Preparation of floating polymer-valsartan delivery systems using supercritical CO2" in Journal of Polymer Research, 28 (2021):74,
https://doi.org/10.1007/s10965-021-02440-1 . .

TY  - CONF
AU  - Milošević, Ksenija
AU  - Janjić, Ognjen
AU  - Lučić Škorić, Marija
AU  - Kalagasidis Krušić, Melina
PY  - 2019
UR  - https://www.shd.org.rs/index.php/abstracts-56
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3300
AB  - Textile industry wastewater represents a serious environmental problem because it contains different dyes and toxic substances used during the production and dyeing of textile. Thus, it is necessary to investigate the removal of dyes from wastewater using a simple method such as sorption. Since different salts are used during the dyeing of textile, anions and cations are present in wastewaters and they can affect the process of dye removal. In this paper, the influence of several anions on the removal of textile dyes was investigated. Chitosan and methacrylic acid-based hydrogels obtained by free-radical polymerization and cross-linked with N,N'-methylenebisacrylamide were used as sorbents. Removal of two textile dyes was investigated (anionic dye C.I. Acid Orange 7 and cationic dye C.I. Basic Red 1) at two different temperatures (25 and 50 ° C). The influence of anions on the removal was evaluated using sodium compounds dissolved in dye solutions (NaCl, CH3COONa, Na2CO3, Na2HPO4, NaH2PO4, NaNO3, NaOH). It has been found that hydrogel degree of swelling increased significantly with the increase of pH of the dye solution. The presence of different ions affected the sorption capacity of hydrogels and the best results were obtained when NaH2PO4 and NaNO3 were present.
AB  - Otpadne vode tekstilne industrije predstavljaju ozbiljan ekološki problem, jer u sebi sadrže različite boje i toksične supstance koje se upotrebljavaju tokom proizvodnje i bojenja tekstila. Stoga, potrebno je da se ispita mogućnost uklanjanja boja iz otpadnih voda tekstilne industrije jednostavnom metodom sorpcije. Kako se u procesu bojenja tekstila koriste različite soli, u ovim otpadnim vodama često su prisutni anjoni i katjoni koji mogu da utiču na sam proces uklanjanja boja. U ovom radu analiziran je uticaj nekoliko anjona na uklanjanje boja za tekstil pomoću hidrogelova na bazi hitozana. Korišćeni hidrogelovi su kopolimeri hitozana i metakrilne kiseline dobijeni slobodno-radikalskom polimerizacijom, a kao umreživač je upotrebljen N,N’-metilenbisakrilamid. Anjonska boja C.I. Acid Orange 7 i katjonska boja C.I. Basic Red 1 su korišćene u model vodama, a uklanjanje boja je izvedeno na dve različite temperature (25 i 50 C). Uticaj anjona je ispitan dodatkom natrijumovih jedinjenja u rastvore boja (NaCl, CH3COONa, Na2CO3, Na2HPO4, NaH2PO4, NaNO3, NaOH). Utvrđeno je da hidrogelovi izrazito bubre sa povećanjem pH rastvora. Prisustvo različitih jona utiče na kapacitet sorpcije, a najbolji rezultati su dobijeni kada su u rastvoru prisutne soli NaH2PO4 i NaNO3.
PB  - Serbian Chemical Society, Belgrade / Srpsko hemijsko društvo, Beograd
C3  - 56th Meeting of the Serbian chemical Society - Book of Abstracts / 56. Savetovanje Srpskog hemijskog društva - Kratki izvodi radova, Niš 7-8.9. 2019.
T1  - The effect of anions on the removal of dyes from textile industry wastewater
T1  - Uticaj anjona na uklanjanje boja iz otpadnih voda tekstilne industrije
SP  - 76
UR  - https://hdl.handle.net/21.15107/rcub_cer_3300
ER  - 

@conference{
author = "Milošević, Ksenija and Janjić, Ognjen and Lučić Škorić, Marija and Kalagasidis Krušić, Melina",
year = "2019",
abstract = "Textile industry wastewater represents a serious environmental problem because it contains different dyes and toxic substances used during the production and dyeing of textile. Thus, it is necessary to investigate the removal of dyes from wastewater using a simple method such as sorption. Since different salts are used during the dyeing of textile, anions and cations are present in wastewaters and they can affect the process of dye removal. In this paper, the influence of several anions on the removal of textile dyes was investigated. Chitosan and methacrylic acid-based hydrogels obtained by free-radical polymerization and cross-linked with N,N'-methylenebisacrylamide were used as sorbents. Removal of two textile dyes was investigated (anionic dye C.I. Acid Orange 7 and cationic dye C.I. Basic Red 1) at two different temperatures (25 and 50 ° C). The influence of anions on the removal was evaluated using sodium compounds dissolved in dye solutions (NaCl, CH3COONa, Na2CO3, Na2HPO4, NaH2PO4, NaNO3, NaOH). It has been found that hydrogel degree of swelling increased significantly with the increase of pH of the dye solution. The presence of different ions affected the sorption capacity of hydrogels and the best results were obtained when NaH2PO4 and NaNO3 were present., Otpadne vode tekstilne industrije predstavljaju ozbiljan ekološki problem, jer u sebi sadrže različite boje i toksične supstance koje se upotrebljavaju tokom proizvodnje i bojenja tekstila. Stoga, potrebno je da se ispita mogućnost uklanjanja boja iz otpadnih voda tekstilne industrije jednostavnom metodom sorpcije. Kako se u procesu bojenja tekstila koriste različite soli, u ovim otpadnim vodama često su prisutni anjoni i katjoni koji mogu da utiču na sam proces uklanjanja boja. U ovom radu analiziran je uticaj nekoliko anjona na uklanjanje boja za tekstil pomoću hidrogelova na bazi hitozana. Korišćeni hidrogelovi su kopolimeri hitozana i metakrilne kiseline dobijeni slobodno-radikalskom polimerizacijom, a kao umreživač je upotrebljen N,N’-metilenbisakrilamid. Anjonska boja C.I. Acid Orange 7 i katjonska boja C.I. Basic Red 1 su korišćene u model vodama, a uklanjanje boja je izvedeno na dve različite temperature (25 i 50 C). Uticaj anjona je ispitan dodatkom natrijumovih jedinjenja u rastvore boja (NaCl, CH3COONa, Na2CO3, Na2HPO4, NaH2PO4, NaNO3, NaOH). Utvrđeno je da hidrogelovi izrazito bubre sa povećanjem pH rastvora. Prisustvo različitih jona utiče na kapacitet sorpcije, a najbolji rezultati su dobijeni kada su u rastvoru prisutne soli NaH2PO4 i NaNO3.",
publisher = "Serbian Chemical Society, Belgrade / Srpsko hemijsko društvo, Beograd",
journal = "56th Meeting of the Serbian chemical Society - Book of Abstracts / 56. Savetovanje Srpskog hemijskog društva - Kratki izvodi radova, Niš 7-8.9. 2019.",
title = "The effect of anions on the removal of dyes from textile industry wastewater, Uticaj anjona na uklanjanje boja iz otpadnih voda tekstilne industrije",
pages = "76",
url = "https://hdl.handle.net/21.15107/rcub_cer_3300"
}

Milošević, K., Janjić, O., Lučić Škorić, M.,& Kalagasidis Krušić, M.. (2019). The effect of anions on the removal of dyes from textile industry wastewater. in 56th Meeting of the Serbian chemical Society - Book of Abstracts / 56. Savetovanje Srpskog hemijskog društva - Kratki izvodi radova, Niš 7-8.9. 2019.
Serbian Chemical Society, Belgrade / Srpsko hemijsko društvo, Beograd., 76.
https://hdl.handle.net/21.15107/rcub_cer_3300

Milošević K, Janjić O, Lučić Škorić M, Kalagasidis Krušić M. The effect of anions on the removal of dyes from textile industry wastewater. in 56th Meeting of the Serbian chemical Society - Book of Abstracts / 56. Savetovanje Srpskog hemijskog društva - Kratki izvodi radova, Niš 7-8.9. 2019.. 2019;:76.
https://hdl.handle.net/21.15107/rcub_cer_3300 .

Milošević, Ksenija, Janjić, Ognjen, Lučić Škorić, Marija, Kalagasidis Krušić, Melina, "The effect of anions on the removal of dyes from textile industry wastewater" in 56th Meeting of the Serbian chemical Society - Book of Abstracts / 56. Savetovanje Srpskog hemijskog društva - Kratki izvodi radova, Niš 7-8.9. 2019. (2019):76,
https://hdl.handle.net/21.15107/rcub_cer_3300 .

TY  - CONF
AU  - Šešlija, Sanja
AU  - Nešić, Aleksandra
AU  - Lučić Škorić, Marija
AU  - Kalagasidis Krušić, Melina
AU  - Santagata, G.
AU  - Malinconico, M.
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/2406
AB  - The present paper reports on pectin based films modified with carboxymethyl cellulose intended for food packaging. The films are prepared by solvent-casting method with different carboxymethyl cellulose content and cross-linker concentration (Ca2+ ions) in the presence of glycerol as a plasticizer. FT-IR spectra of the prepared films propose that carboxyl group from pectin are mainly involved in interactions with CMC, whereas −OH groups are mainly involved in self-associated hydrogen bonding of neat polymers. Further, an addition of carboxymethyl cellulose improved mechanical properties compared to pure pectin films, while TGA analysis confirmed satisfying thermal stability regarding their potential application as packaging material. Finally, water vapor permeability values are in the range of 1.32 × 10−7 up to 2.03 × 10−7 g/m h Pa.
PB  - Wiley-VCH Verlag
C3  - Macromolecular Symposia
T1  - Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material
VL  - 378
IS  - 1
SP  - 1600163
DO  - 10.1002/masy.201600163
ER  - 

@conference{
author = "Šešlija, Sanja and Nešić, Aleksandra and Lučić Škorić, Marija and Kalagasidis Krušić, Melina and Santagata, G. and Malinconico, M.",
year = "2018",
abstract = "The present paper reports on pectin based films modified with carboxymethyl cellulose intended for food packaging. The films are prepared by solvent-casting method with different carboxymethyl cellulose content and cross-linker concentration (Ca2+ ions) in the presence of glycerol as a plasticizer. FT-IR spectra of the prepared films propose that carboxyl group from pectin are mainly involved in interactions with CMC, whereas −OH groups are mainly involved in self-associated hydrogen bonding of neat polymers. Further, an addition of carboxymethyl cellulose improved mechanical properties compared to pure pectin films, while TGA analysis confirmed satisfying thermal stability regarding their potential application as packaging material. Finally, water vapor permeability values are in the range of 1.32 × 10−7 up to 2.03 × 10−7 g/m h Pa.",
publisher = "Wiley-VCH Verlag",
journal = "Macromolecular Symposia",
title = "Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material",
volume = "378",
number = "1",
pages = "1600163",
doi = "10.1002/masy.201600163"
}

Šešlija, S., Nešić, A., Lučić Škorić, M., Kalagasidis Krušić, M., Santagata, G.,& Malinconico, M.. (2018). Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material. in Macromolecular Symposia
Wiley-VCH Verlag., 378(1), 1600163.
https://doi.org/10.1002/masy.201600163

Šešlija S, Nešić A, Lučić Škorić M, Kalagasidis Krušić M, Santagata G, Malinconico M. Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material. in Macromolecular Symposia. 2018;378(1):1600163.
doi:10.1002/masy.201600163 .

Šešlija, Sanja, Nešić, Aleksandra, Lučić Škorić, Marija, Kalagasidis Krušić, Melina, Santagata, G., Malinconico, M., "Pectin/Carboxymethylcellulose Films as a Potential Food Packaging Material" in Macromolecular Symposia, 378, no. 1 (2018):1600163,
https://doi.org/10.1002/masy.201600163 . .